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Green synthesis and characterization of bisphosphonate conjugated gold nanoparticle with < em > Asparagus racemosus < /em > root extract
Bioinformation. 2022 Mar 31;18(3):160-164. doi: 10.6026/97320630018160. eCollection 2022.ABSTRACTBisphosphonates improve orthodontic anchorage. More targeted action of this drug can be achieved through its conjugation with gold nanoparticles. Asparagus racemosus is a green edible medicinal plant used in Ayurvedic preparations to treat aging, vigor, immunity, longevity, and skeletal issues. Therefore, it is of interest to report the green synthesized Bisphosphonate conjugated gold nanoparticles with Asparagus racemosus extract and to characterize them.PMID:36518141 | PMC:PMC9722419 | DOI:10.6026/97320630018160 (Source: Bioinformation)
Source: Bioinformation - December 15, 2022 Category: Bioinformatics Authors: Sruthi Harikrishnan Navaneethan Ramasamy Rajeshkumar Shanmugam Source Type: research

[ASAP] Distinct Quality Changes of Asparagus during Growth by Widely Targeted Metabolomics Analysis
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.2c05743 (Source: Journal of Agricultural and Food Chemistry)
Source: Journal of Agricultural and Food Chemistry - December 8, 2022 Category: Food Science Authors: Pingxiang Liu, Rui Gao, Lei Gao, Jingxiu Bi, Yuying Jiang, Xiao Zhang, and Yutao Wang Source Type: research

Asparagus cochinchinensis: A review of its botany, traditional uses, phytochemistry, pharmacology, and applications
Asparagus cochinchinensis (Lour.) Merr. (A. cochinchinensis) is a traditional herbal medicine that is used to treat constipation, fever, pneumonia, stomachache, tracheitis, rhinitis, cataract, acne, urticaria. More than 90 compounds have been identified from different structural types in A. cochinchinensis, including steroidal saponins, C21-steroides, lignans, polysaccharides, amino acids, etc. These bioactive ingredients make A. cochinchinensis remarkable for its pharmacological effects on anti-asthma, anti-inflammatory, anti-oxidation, anti-tumor, improving Alzheimer’s disease, neuroprotection, gut health-promoting and...
Source: Frontiers in Pharmacology - November 30, 2022 Category: Drugs & Pharmacology Source Type: research

Sensors, Vol. 22, Pages 9270: Detection of Green Asparagus Using Improved Mask R-CNN for Automatic Harvesting
ngjin Qin Advancements in deep learning and computer vision have led to the discovery of numerous effective solutions to challenging problems in the field of agricultural automation. With the aim to improve the detection precision in the autonomous harvesting process of green asparagus, in this article, we proposed the DA-Mask RCNN model, which utilizes the depth information in the region proposal network. Firstly, the deep residual network and feature pyramid network were combined to form the backbone network. Secondly, the DA-Mask RCNN model added a depth filter to aid the softmax function in anchor classification. A...
Source: Sensors - November 28, 2022 Category: Biotechnology Authors: Xiangpeng Liu Danning Wang Yani Li Xiqiang Guan Chengjin Qin Tags: Article Source Type: research

Molecules, Vol. 27, Pages 8181: Yamogenin-Induced Cell Cycle Arrest, Oxidative Stress, and Apoptosis in Human Ovarian Cancer Cell Line
In this study, we evaluated the effect of yamogenin on human ovarian cancer SKOV-3 cells in vitro by determining the cellular factors that trigger cell death. The viability of the cells was assessed with a Real-Time xCELLigence system and the cell cycle arrest with flow cytometry. The activity of initiator and executioner caspases (-8, -9, and -3/7) was estimated with luminometry and flow cytometry, respectively. The mitochondrial membrane depolarization, the level of oxidative stress, and DNA damage in the yamogenin-treated cells were also evaluated by flow cytometry. Genes expression analysis at the mRNA level was conduc...
Source: Molecules - November 24, 2022 Category: Chemistry Authors: Justyna Stefanowicz-Hajduk Anna Hering Magdalena Gucwa Monika Czerwi ńska J. Renata Ochocka Tags: Article Source Type: research

Molecules, Vol. 27, Pages 7676: Phenylpropanoid Derivatives from the Tuber of Asparagus cochinchinensis with Anti-Inflammatory Activities
i Yang Yu Three undescribed phenylpropanoid derivatives, including two new bibenzyl constituents (1&ndash;2), one new stilbene constituent (3), together with five known compounds stilbostemin F (4), dihydropinosylvin (5), 2-(4-hydroxyphenyl)ethyl benzoate (6), 1-(4-hydroxybenzoyl)ethanone (7), and 4-hydroxy-3-prenylbenzoic acid (8), were isolated from the tuber of Asparagus cochinchinensis. The structures of 1&ndash;8 were elucidated according to UV, IR, HRMS, 1D and 2D-NMR methods together with the published literature. All of the isolated compounds were assessed for anti-inflammatory activity by act...
Source: Molecules - November 8, 2022 Category: Chemistry Authors: Jingyi Yue Nan Zhang Tao Xu Jutao Wang Baixiang Cai Yang Yu Tags: Article Source Type: research

Asparagus cochinchinensis alleviates disturbances of lipid metabolism and gut microbiota in high-fat diet-induced obesity mice
Asparagus cochinchinensis is a valuable traditional Chinese medicine that has anti-inflammatory ability and effectively regulates the dysbiosis within the body. Obesity is usually characterized by chronic low-grade inflammation with aberrant gut microbiota. However, the role of Asparagus cochinchinensis against obesity remains unknown. Therefore, a high-fat diet (HFD)-induced obese mouse model with or without aqueous extract from Asparagus cochinchinensis root (ACE) treatment was established herein to determine whether ACE alleviated obesity and its involved mechanisms. Our results showed that ACE root administration signi...
Source: Frontiers in Pharmacology - October 12, 2022 Category: Drugs & Pharmacology Source Type: research

Protective effects of Asparagus officinalis (asparagus) against lead toxicity in mice
Environ Sci Pollut Res Int. 2022 Oct 11. doi: 10.1007/s11356-022-23540-5. Online ahead of print.ABSTRACTOne of the most prevalent harmful heavy metals is lead (Pb). It is generally recognized to be harmful to the testicles. Asparagus officinalis has many saponins, flavonoids, and other phenolics with strong antioxidant and anti-inflammatory effects. The effects of A. officinalis (asparagus) aqueous extract (AOAE) on testicular damage caused by lead acetate (PbAc) were investigated in this study. In this way, 20 mg/kg PbAc was injected intraperitoneally 2 h after mice were administered 400 mg/kg AOAE orally for 14 days. In ...
Source: Environmental Science and Pollution Research International - October 11, 2022 Category: Environmental Health Authors: Nouf M Alyami Rafa Almeer Hanadi M Alyami Source Type: research