Phytochemical screening and anti-implantation activity of Asparagus africanus root extract in female Sprague–Dawley rats

In conclusion, the aqueous extract A. africanus has anti-implantation effect in female rats and is safe up to 2000 mg/kg bw. In addition, it contains some potential steroidal saponins, which could be used to explain its an ti-implantation activity, however this finding needs further pharmacological studies to confirm the antifertility activities.
Source: Revista Brasileira de Farmacognosia - Category: Drugs & Pharmacology Source Type: research

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Publication date: February 2020Source: The Lancet Global Health, Volume 8, Issue 2Author(s): Louise Kuhn, Rakiya Saidu, Rosalind Boa, Ana Tergas, Jennifer Moodley, David Persing, Scott Campbell, Wei-Yann Tsai, Thomas C Wright, Lynette DennySummaryBackgroundHPV-based screen and treat is the recommended approach for cervical cancer screening in low-resource settings, but quite low specificity of human papillomavirus (HPV) testing, particularly in women living with HIV, leads to overtreatment. We evaluated whether HPV type restriction and more stringent cutoffs on Xpert HPV optimise performance characteristics of this assay f...
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
In conclusion, our diagnostic prediction model uses easily obtainable information to identify children at increased risk of high blood pressure, offering an opportunity for targeted screening. This model enables to detect a higher proportion of children with high blood pressure than a strategy based on child overweight only.
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Authors: Yang L, Li M, Liu X, Wu M, Zhang J, Zhao L, Ding G, Yang X Abstract BACKGROUND: Remarkable achievements have been made for over two decades by implementing a universal salt iodization policy in China. However, changes in the standards and manufacturing of iodized salt have made it necessary to regularly monitor iodine intake and thyroid function in the population. Therefore, we aimed to evaluate iodine nutritional status using thyroid function and urinary iodine levels in pregnant women via a national survey. METHODS: Participants included pregnant women enrolled in the 2015 National Nutrition and Heal...
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
Conclusions deriving from these studies, for example that prevention is cost saving, need to be carefully interpreted as they rely on many assumptions. PMID: 31964247 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
Researchers at the Laboratory of Bionanophotonic Systems (BIOS) at EPFL's School of Engineering have developed an optical biosensor that slashes the sepsis diagnosis time from several days to just a few minutes. Their approach draws on recent developments in nanotechnology and on light effects at a nanoscale to create a highly portable, easy-to-use device that can rapidly detect sepsis biomarkers in a patient's bloodstream. And their device takes just a few minutes to deliver a result, like a pregnancy test. Because the biosensor uses a plasmonics technology, it can be built from small, inexpensive components, yet it can a...
Source: MDDI - Category: Medical Devices Authors: Tags: IVD Source Type: news
Authors: Johansen SL, Stenhaug BA, Robakis TK, Williams KE, Cullen MR Abstract OBJECTIVE: To compare risk for postpartum depression across prior psychiatric diagnoses. METHODS: The deidentified Optum© Clinformatics Data Mart of national commercial insurance claims was used to identify 1,166,577 women of reproductive age with first-observed incidence of pregnancy across all 50 United States from 2003 to 2016. Women with insurance coverage for at least 6 months prior to conception and following delivery were eligible (n = 336,522). Psychiatric diagnoses prior to pregnancy were identified by ICD-9-CM and ICD-...
Source: Journal of Clinical Psychiatry - Category: Psychiatry Tags: J Clin Psychiatry Source Type: research
This study aimed to decipher the lipidomics pathways involved in pathophysiology of sPTB.MethodsBlood samples were taken from SCreening fOr Pregnancy Endpoints (SCOPE), an international study that recruited 5628 nulliparous women, with a singleton low-risk pregnancy. Our analysis focused on plasma from SCOPE in Cork. Discovery profiling of the samples was undertaken using liquid chromatography-mass spectrometry Lipidomics, and features significantly altered between sPTB (n  = 16) and Control (n = 32) groups were identified using empirical Bayes testing, adjusting for multiple comparisons.Results...
Source: Metabolomics - Category: Biology Source Type: research
DiscussionMainly in the early first trimester, larger placental volumetric parameters are associated with lower pressure and more FMVD in the fetoplacental vasculature after delivery. This may suggest that larger and/or more vascularized placentas in early pregnancy have better adaptive mechanisms and possibly lead to better pregnancy outcomes.
Source: Frontiers in Physiology - Category: Physiology Source Type: research
The Trump administration granted visa officers more power to block pregnant women from visiting the United States if applicants were believed to be traveling to give birth.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Visas Immigration and Emigration Pregnancy and Childbirth United States Politics and Government Citizenship and Naturalization Diplomatic Service, Embassies and Consulates State Department Trump, Donald J Source Type: news
Publication date: Available online 22 January 2020Source: Revista Española de Cardiología (English Edition)Author(s): Ernesto Valero, Jessika González-D’Gregorio, Nieves Carbonell, Mónica García-Simón, José Ferreres, Juan Sanchis
Source: Revista Espanola de Cardiologia - Category: Cardiology Source Type: research
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