Now It’s In The Air We Breathe
When I started practicing medicine, I made a discovery that changed my view of the world forever. It was something few understood at the time. I’m talking about an “alien molecule” that gets into your blood and reprograms your cells to become more “feminine.” When this happens to women, it throws off their natural cycles, makes them gain weight, and pushes them emotionally into a very anxious and frustrated state. For men, this “invader” makes them soft, fat, depressed, and unable to perform. When I first started testing for this back in the 1990s, other physicians thought I was off my rocker. Twenty five years later, I’m not alone in my concern. I’m talking about a chemical toxin that looks and acts like the hormone estrogen. If you’re a regular reader, you know I’ve talked to you about this before. And I’ll keep saying it, because we have new evidence it’s getting worse. The problem is that these chemical estrogens are in just about everything we come in contact with during our daily lives. It’s no longer a matter of trying to avoid plastic bottles made with bisphenol-A or BPA, one of the more popular forms of this chemical. These chemicals are such a problem; they are literally in the air we breathe.1 Researchers from the University of Missouri recently discovered that factories and industrial sites release BPA into the air and water, causing BPA to circulate in the atmosphere as well as ou...
The Pallimed community is invited to participate in the #hpm Tweet Chat this week which help inform and shape a comparative effectiveness research proposal being designed by the Brain Cancer Quality of Life Collaborative, an initiative led by a team of patients, care partners, advocates, neuro-oncologists, and palliative care professionals.The #hpm Tweet Chat is this Wednesday, April 25th, 6-7p PST/9-10p ET.Topics for the chatare available here, in the #hpm chat ’s blog post,How might we introduce palliative care to people with complex neurological conditions, by Liz Salmi and Bethany Kwan, P...
This study included all patients with non-metastatic primary T1 UBC reported to the Swedish National Register of Urinary Bladder Cancer (SNRUBC) from 1997 to 2014, excluding those treated with primary cystectomy. Differences between groups were evaluated using chi-squared tests and logistic regression, and survival was investigated using Kaplan-Meier and log-rank tests and Cox proportional hazards analysis. RESULTS: In all, 7681 patients with T1 UBC (77% male, 23% female) were included. Females were older than males at the time of diagnosis (median age at presentation 76 and 74 years, respectively; p
If the lack of control in the ED, the unfairness &unrealistic expectations by administration, and the chaotic circadian rhythm disruption has depressed your attitude, self confidence and hope for the future and burned you out, I'm here to tell you, there is a better way. Maybe it's a new EM job, or simply cutting work hours. Maybe for someone else, it's another residency, a fellowship, leaving Medicine altogether or something entirely different. What it is for any specific individual, I... Go from burnout to recharged &energized
CONCLUSION: This first national survey revealed a high prevalence of mental disorders. Considering the importance of mental disorders in the general population, it is important to train and involve more nurses and general practitioners in the identification and management of these disorders as there are very few specialists in the field at present. PMID: 29673721 [PubMed - as supplied by publisher]
Conclusion: Significant changes in oxidative stress indicators were observed in this study, confirming previous studies. Increased levels of oxidants were shown with increased disease severity rather than with the number of manic episodes. Systematic studies, including of each period of the disorder, are needed for using the findings indicating deterioration of oxidative parameters. PMID: 29674601 [PubMed - as supplied by publisher]
Conclusion: An adolescent psychological autopsy study using the K-PAC-A is expected to provide useful evidence for suicide prevention policies and intervention plans for Korean youths in the future. PMID: 29674599 [PubMed - as supplied by publisher]
It appears the prescribing of Subsys in non-cancer patients is now considered a crime by the federal government. Las Vegas pain physician arrested for illegal fentanyl distribution: 5 things to know Written by Brian Zimmerman | February 19, 2018 www.beckershospitalreview.com Police arrested a Las Vegas pain management physician Feb. 13 for charges related to the unlawful distribution of fentanyl and healthcare fraud. Here... Subsys Rx for Non-cancer Patients Is Considered a Criminal Act
Authors: Gao Y, Xu Y, Wang J, Yang X, Wen L, Feng J Abstract Long noncoding RNAs (lncRNAs) have been acknowledged as important regulators in various human cancers. LncRNA MNX1-AS1has been shown to be an oncogene in epithelial ovarian cancer. However, the function of MNX1-AS1 in glioblastoma (GBM) remains largely unknown. Here, we found that the expression of MNX1-AS1 was significantly upregulated in GBM tissues and cell lines. Knockdown of MNX1-AS1 significantly inhibited the proliferation, migration and invasion of GBM cells. In terms of mechanism, we found that MNX1-AS1 could bind to miR-4443 in GBM cells. Overex...
This study also identified cordycepin derivatives with promising pharmacological and pharmacokinetic properties for further investigation in the development of new treatments for endometrial cancer. PMID: 29673423 [PubMed - as supplied by publisher]
Authors: Wang L, Li Q, Ye Z, Qiao B Abstract Renal carcinoma greatly threatens human health, but the involved molecular mechanisms are far from complete understanding. As a master oncogene driving the initiation of many other cancers, Pokemon has not been established to be associated with renal cancer. Our data revealed that Pokemon is highly expressed in renal carcinoma specimen and cell lines, compared with normal cells. The silencing of Pokemon suppressed the proliferation and invasion of renal cancer cells. Pokemon overexpression rendered normal cells with higher proliferation rates and invasiveness. Animal stu...
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