The yield of routine laboratory examination in osteoporosis evaluation in primary care
ConclusionsWe identified a low prevalence of laboratory abnormalities in a primary care population of older women and the majority of these findings had no medical consequences. (Source: Osteoporosis International)
Source: Osteoporosis International - April 19, 2024 Category: Orthopaedics Source Type: research
The role of vitamin D against COVID-19 infection, progression and severity
CONCLUSION: People hospitalized for COVID-19 should be checked for vitamin D status and supplemented, and high-dose-in testing should be considered in the recovery trial. More importantly, screening for malnutrition and the administration of the best nutritional supplements are essential for the immune system of the human body to function as it should be. Thus, nutritional supplementation is crucial for people with risk factors as well as older adults with compromised immune systems.PMID:38640148 | DOI:10.3233/HAB-240009 (Source: Human Antibodies)
Source: Human Antibodies - April 19, 2024 Category: Biochemistry Authors: Hiba Sh Ahmed Hind Sh Ahmed Haylim N Abud Source Type: research
VDR is a potential prognostic biomarker and positively correlated with immune infiltration: a comprehensive pan-cancer analysis with experimental verification
In conclusion, VDR is a potential prognostic biomarker and positively correlated with immune infiltration as well as stromal or immune components in TME in multiple human cancers.PMID:38639057 | DOI:10.1042/BSR20231845 (Source: Bioscience Reports)
Source: Bioscience Reports - April 19, 2024 Category: Biomedical Science Authors: Xuedi Xia Feng Xu Dexing Dai An Xiong Ruoman Sun Yali Ling Lei Qiu Rui Wang Ya Ding Miaoying Lin Haibo Li Zhongjian Xie Source Type: research
The role of vitamin D against COVID-19 infection, progression and severity
CONCLUSION: People hospitalized for COVID-19 should be checked for vitamin D status and supplemented, and high-dose-in testing should be considered in the recovery trial. More importantly, screening for malnutrition and the administration of the best nutritional supplements are essential for the immune system of the human body to function as it should be. Thus, nutritional supplementation is crucial for people with risk factors as well as older adults with compromised immune systems.PMID:38640148 | DOI:10.3233/HAB-240009 (Source: Human Antibodies)
Source: Human Antibodies - April 19, 2024 Category: Biochemistry Authors: Hiba Sh Ahmed Hind Sh Ahmed Haylim N Abud Source Type: research
VDR is a potential prognostic biomarker and positively correlated with immune infiltration: a comprehensive pan-cancer analysis with experimental verification
In conclusion, VDR is a potential prognostic biomarker and positively correlated with immune infiltration as well as stromal or immune components in TME in multiple human cancers.PMID:38639057 | DOI:10.1042/BSR20231845 (Source: Bioscience Reports)
Source: Bioscience Reports - April 19, 2024 Category: Biomedical Science Authors: Xuedi Xia Feng Xu Dexing Dai An Xiong Ruoman Sun Yali Ling Lei Qiu Rui Wang Ya Ding Miaoying Lin Haibo Li Zhongjian Xie Source Type: research
The role of vitamin D against COVID-19 infection, progression and severity
CONCLUSION: People hospitalized for COVID-19 should be checked for vitamin D status and supplemented, and high-dose-in testing should be considered in the recovery trial. More importantly, screening for malnutrition and the administration of the best nutritional supplements are essential for the immune system of the human body to function as it should be. Thus, nutritional supplementation is crucial for people with risk factors as well as older adults with compromised immune systems.PMID:38640148 | DOI:10.3233/HAB-240009 (Source: Human Antibodies)
Source: Human Antibodies - April 19, 2024 Category: Biochemistry Authors: Hiba Sh Ahmed Hind Sh Ahmed Haylim N Abud Source Type: research
Vitamin D3 among neonates born after in vitro fertilization compared with neonates from the general population
ConclusionsIn this study, children born after in vitro fertilization have a higher vitamin D3 than a random sample of neonates in Denmark. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - April 19, 2024 Category: OBGYN Authors: Karen Christina Walker,
Sofie Gry Pristed,
Fanney Thorsteinsdottir,
Ina Olmer Specht,
Arieh Cohen,
Berit Lilienthal Heitmann,
Ulrik Schi øler Kesmodel Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Viruses, Vol. 16, Pages 639: Vitamin D Levels and SARS-CoV-2 Infection among Medically Underserved Populations in the Minority and Rural Coronavirus Insights Study
Conclusion: Vitamin D levels were associated with an increased risk of SARS-CoV-2 infection. Hispanic/Latino and Black, non-Hispanic compared to White, non-Hispanic participants were at increased odds for infection, after adjusting for race/ethnicity and age. (Source: Viruses)
Source: Viruses - April 19, 2024 Category: Virology Authors: Makella S. Coudray Shantoy Hansel Salvatore Alesci William A. Meyer Robert H. Christenson Latrice G. Landry Christina Edwards Gary Puckrein Derrick J. Forney Ola Akinboboye Tags: Article Source Type: research
Vitamin D status of pregnant women with obesity in the United Kingdom and its association with pregnancy outcomes: a secondary analysis of the UPBEAT study
Br J Nutr. 2024 Apr 18:1-28. doi: 10.1017/S0007114524000862. Online ahead of print.ABSTRACTPrenatal vitamin D deficiency is widely reported and may affect perinatal outcomes. In this secondary analysis of the UK Pregnancies Better Eating and Activity Trial (UPBEAT), we examined vitamin D status and its relationship with selected pregnancy outcomes in women with obesity (BMI≥30kg/m2) from multi-ethnic inner-city settings in the UK. Determinants of vitamin D status at a mean of 17±1 weeks' gestation were assessed using multivariable linear regression and reported as percent differences in serum hydroxyvitamin D (25(OH)D)....
Source: The British Journal of Nutrition - April 18, 2024 Category: Nutrition Authors: Karen M O'Callaghan Katarzyna G Nowak Kathryn V Dalrymple Lucilla Poston Jessica Rigutto-Farebrother Ola F Quotah Sara L White Angela C Flynn UPBEAT Consortium Source Type: research
The effects of cholecalciferol and afamelanotide on vitamin D levels in erythropoietic protoporphyria; a multicentre cohort study
CONCLUSION: Cholecalciferol remains essential for treatment of vitamin D deficiency in EPP, irrespective of new treatment options like afamelanotide. Afamelanotide treatment did not affect vitamin D levels. We suggest that future guidelines include continuous monitoring of vitamin D and prescription of cholecalciferol in all patients with EPP, including those treated with afamelanotide.PMID:38634774 | DOI:10.1093/bjd/ljae148 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 18, 2024 Category: Dermatology Authors: Louisa G Kluijver Mitra Nekouei Shahraki Margreet A E M Wagenmakers Bettina E Hanssen Viola Kuerten Kathrin Schelonke Bernhard Homey Janneke G Langendonk Source Type: research
The Role of Blood Testing in Prevention, Diagnosis, and Management of Chronic Diseases: A Review
Am J Med Sci. 2024 Apr 16:S0002-9629(24)01169-8. doi: 10.1016/j.amjms.2024.04.009. Online ahead of print.ABSTRACTBlood tests are vital to prevention, diagnosis, and management of chronic diseases. Despite this, it can be challenging to construct a comprehensive view of the clinical importance of blood testing because relevant literature is typically fragmented across different disease areas and patient populations. This lack of collated evidence can also make it difficult for primary care providers to adhere to best practices for blood testing across different diseases and guidelines. Thus, this review article synthesizes ...
Source: The American Journal of the Medical Sciences - April 18, 2024 Category: General Medicine Authors: Imelda Cabalar Thu H Le Abigail Silber Matthew O'Hara Bilal Abdallah Monisha Parikh Robert Busch Source Type: research
Vitamin D status of pregnant women with obesity in the United Kingdom and its association with pregnancy outcomes: a secondary analysis of the UPBEAT study
Br J Nutr. 2024 Apr 18:1-28. doi: 10.1017/S0007114524000862. Online ahead of print.ABSTRACTPrenatal vitamin D deficiency is widely reported and may affect perinatal outcomes. In this secondary analysis of the UK Pregnancies Better Eating and Activity Trial (UPBEAT), we examined vitamin D status and its relationship with selected pregnancy outcomes in women with obesity (BMI≥30kg/m2) from multi-ethnic inner-city settings in the UK. Determinants of vitamin D status at a mean of 17±1 weeks' gestation were assessed using multivariable linear regression and reported as percent differences in serum hydroxyvitamin D (25(OH)D)....
Source: The British Journal of Nutrition - April 18, 2024 Category: Nutrition Authors: Karen M O'Callaghan Katarzyna G Nowak Kathryn V Dalrymple Lucilla Poston Jessica Rigutto-Farebrother Ola F Quotah Sara L White Angela C Flynn UPBEAT Consortium Source Type: research
The association between vitamin D levels and psoriasis in people aged 40-79 years
Br J Dermatol. 2024 Apr 17;190(5):e54. doi: 10.1093/bjd/ljae120.NO ABSTRACTPMID:38630933 | DOI:10.1093/bjd/ljae120 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - April 17, 2024 Category: Dermatology Source Type: research
Low skeletal muscle mass index is independently associated with low bone mineral density in kidney transplant recipients: a retrospective observational cohort study
CONCLUSIONS: In kidney transplant recipients, an independent association between lower bone mineral density and skeletal muscle mass index was observed in both sexes.PMID:38630339 | DOI:10.1007/s40620-024-01931-w (Source: Journal of Nephrology)
Source: Journal of Nephrology - April 17, 2024 Category: Urology & Nephrology Authors: Morikuni Nishihira Yutaka Matsuoka Mayuko Hori Makoto Tsujita Kaoru Yasuda Satoshi Ashimine Kohei Ishiyama Kazuharu Uchida Kunio Morozumi Takaaki Kobayashi Source Type: research
Gene expression profiling of vitamin D metabolism enzymes in leukemia and lymphoma patients: molecular aspect interplay of VDR, CYP2R1, and CYP24A1
CONCLUSION: The study revealed a noteworthy difference in VDR protein levels between men and women. The highest mean CYP24A1 protein levels were observed in the age group > 60 years. This study found a significant, moderately positive correlation between VDR protein levels and CYP24A1 protein levels in the male and vitamin D sufficiency groups. In addition, a significant positive correlation was found between VDR mRNA levels and CYP2R1 mRNA levels, VDR mRNA levels and CYP2R1 mRNA levels, and CYP2R1 mRNA levels and CYP24A1 mRNA levels. However, the expression of these genes does not correlate with the protein levels of i...
Source: Molecular Biology Reports - April 17, 2024 Category: Molecular Biology Authors: Anggraini Iriani Andhika Rachman Marsya Kaila Fatina Rizka Kurnia Gemilang Andi Trisnandi Media Fitri Isma Nugraha Source Type: research
