Vitamin D status in children
J Pediatr (Rio J). 2024 Apr 8:S0021-7557(24)00037-8. doi: 10.1016/j.jped.2024.04.001. Online ahead of print.NO ABSTRACTPMID:38604241 | DOI:10.1016/j.jped.2024.04.001 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - April 11, 2024 Category: Pediatrics Authors: Roger Bouillon Leen Antonio Nick Narinx Source Type: research

Modulatory interactions of T-2 and deoxynivalenol mycotoxins on murine femoral development and osteological integrity
In this study, we conducted a systematic assessment of the effectsof Deoxynivalenol (DON) and T-2 mycotoxins on the developmental processes and structural integrity of murine femurs, considering both the isolated and synergistic effects of these toxins. To this end, we divided 72 male mice into nine groups, each subjected to varying dosages of T-2, DON, or their combinations. Over a four-week experimental period, meticulous monitoring was undertaken regarding the mice's body weight, biochemical markers of bone formation and resorption, and the activity of relevant cells. To comprehensively evaluate alterations in bone stru...
Source: Food and Chemical Toxicology - April 11, 2024 Category: Food Science Authors: Cong Yao Shuichu Hao Chun Zhang Li Liu Yumeng Jia Peilin Meng Cuiyan Wu Xiong Guo Source Type: research

Vitamin D status in children
J Pediatr (Rio J). 2024 Apr 8:S0021-7557(24)00037-8. doi: 10.1016/j.jped.2024.04.001. Online ahead of print.NO ABSTRACTPMID:38604241 | DOI:10.1016/j.jped.2024.04.001 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - April 11, 2024 Category: Pediatrics Authors: Roger Bouillon Leen Antonio Nick Narinx Source Type: research

Dilated cardiomyopathy due to hypocalcaemia: a case report
ConclusionThis adds to literature of this rare cause of reversible cardiomyopathy secondary to hypocalcemia reported from the South Asian region of the world. This case highlights the impact of proper treatment improving the heart failure in patients with hypocalcemic cardiomyopathy. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - April 11, 2024 Category: General Medicine Source Type: research

Ambient ultraviolet-B radiation, supplements and other factors interact to impact vitamin D status differently depending on ethnicity: a cross-sectional study
Many determinants of vitamin D status have been well-described, yet supplementation guidelines largely follow a one-size-for-all model and deficiency remains common. We hypothesised that accounting accurately for ultraviolet-B (UVB) radiation and considering interactions could advance understanding of vitamin D status. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 11, 2024 Category: Nutrition Authors: Margaret M. Brennan, Jos van Geffen, Michiel van Weele, Lina Zgaga, Rasha Shraim Source Type: research

Vitamin D as an intervention for improving quadriceps muscle strength in patients after anterior cruciate ligament reconstruction: study protocol for a randomized double-blinded, placebo-controlled clinical trial
The goal of anterior cruciate ligament reconstruction (ACLR) is to restore the preinjury level of knee function to return to play (RTP). However, even after completing the rehabilitation programme, some patien... (Source: Trials)
Source: Trials - April 11, 2024 Category: General Medicine Authors: Michael Tim-yun Ong, Xiaomin Lu, Ben Chi-yin Choi, Siu-Wai Wan, Qianwen Wang, Gene Chi-wai Man, Pauline Po-yee Lui, Daniel Tik-Pui Fong, Daniel Kam-wah Mok and Patrick Shu-hang Yung Tags: Study protocol Source Type: research

Biophysical insight into the binding mechanism of epigallocatechin-3-gallate and cholecalciferol to albumin and its preventive effect against AGEs formation: An in vitro and in silico approach
This article focusses on the interaction and antiglycating potential of (-)-Epigallocatechin-3-gallate (EGCG) and vitamin D in combination using various techniques. The formation of the HSA-EGCG and HSA-vitamin D complex was confirmed by UV and fluorescence spectroscopy. Thermodynamic analysis verified the spontaneity of reaction, and presence of hydrogen bonds and van der Waals interactions. FRET confirms high possibility of energy transfer. Cumulative antiglycation resulted in almost 60 % prevention in AGEs formation, decreased alterations at lysine and arginine, and reduced protein carbonylation. Secondary and tertiary ...
Source: International Journal of Biological Macromolecules - April 10, 2024 Category: Biochemistry Authors: Sana Siddiqui Rizwan Ahmad Yusra Ahmad Abul Faiz Faizy Shagufta Moin Source Type: research

Systematic Review of the roles of Inositol and Vitamin D in improving fertility among patients with Polycystic Ovary Syndrome
Clin Exp Reprod Med. 2024 Apr 11. doi: 10.5653/cerm.2023.06485. Online ahead of print.ABSTRACTPolycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder among reproductive-age women. As a leading cause of anovulatory infertility, it complicates fertility treatments, including in vitro fertilization. The widely accepted 2003 Rotterdam diagnostic criteria for PCOS include sub-phenotypes based on variations in androgen excess, ovulatory dysfunction, and polycystic ovarian morphology. In this systematic review, we examined the impacts of inositol and vitamin D on fertility in PCOS. Adhering to the Preferred ...
Source: Clinical and Experimental Reproductive Medicine - April 10, 2024 Category: Reproduction Medicine Authors: Gitika Katyal Gursharan Kaur Hafsa Ashraf Adiprasad Bodapati Ayesha Hanif Donatus Kaine Okafor Safeera Khan Source Type: research

Biophysical insight into the binding mechanism of epigallocatechin-3-gallate and cholecalciferol to albumin and its preventive effect against AGEs formation: An in vitro and in silico approach
This article focusses on the interaction and antiglycating potential of (-)-Epigallocatechin-3-gallate (EGCG) and vitamin D in combination using various techniques. The formation of the HSA-EGCG and HSA-vitamin D complex was confirmed by UV and fluorescence spectroscopy. Thermodynamic analysis verified the spontaneity of reaction, and presence of hydrogen bonds and van der Waals interactions. FRET confirms high possibility of energy transfer. Cumulative antiglycation resulted in almost 60 % prevention in AGEs formation, decreased alterations at lysine and arginine, and reduced protein carbonylation. Secondary and tertiary ...
Source: International Journal of Biological Macromolecules - April 10, 2024 Category: Biochemistry Authors: Sana Siddiqui Rizwan Ahmad Yusra Ahmad Abul Faiz Faizy Shagufta Moin Source Type: research

Systematic Review of the roles of Inositol and Vitamin D in improving fertility among patients with Polycystic Ovary Syndrome
Clin Exp Reprod Med. 2024 Apr 11. doi: 10.5653/cerm.2023.06485. Online ahead of print.ABSTRACTPolycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder among reproductive-age women. As a leading cause of anovulatory infertility, it complicates fertility treatments, including in vitro fertilization. The widely accepted 2003 Rotterdam diagnostic criteria for PCOS include sub-phenotypes based on variations in androgen excess, ovulatory dysfunction, and polycystic ovarian morphology. In this systematic review, we examined the impacts of inositol and vitamin D on fertility in PCOS. Adhering to the Preferred ...
Source: Clinical and Experimental Reproductive Medicine - April 10, 2024 Category: Reproduction Medicine Authors: Gitika Katyal Gursharan Kaur Hafsa Ashraf Adiprasad Bodapati Ayesha Hanif Donatus Kaine Okafor Safeera Khan Source Type: research