Etidronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women
CONCLUSIONS: This update echoes the key findings of our previous review that etidronate probably makes or may make little to no difference to vertebral and non-vertebral fractures for both primary and secondary prevention.PMID:38591743 | PMC:PMC11003221 | DOI:10.1002/14651858.CD003376.pub4 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - April 9, 2024 Category: General Medicine Authors: George A Wells Shu-Ching Hsieh Joan Peterson Carine Zheng Shannon E Kelly Beverley Shea Peter Tugwell Source Type: research

Short-term effects of Roux-en-Y gastric bypass or gastric sleeve on bone mineral density and calciotropic hormones: a systematic review and meta-analysis
Surg Obes Relat Dis. 2024 Mar 12:S1550-7289(24)00114-X. doi: 10.1016/j.soard.2024.03.007. Online ahead of print.ABSTRACTRoux-en-Y gastric bypass (RYGB) and gastric sleeve (GS) have been associated with significant reductions in bone mineral density (BMD) and fluctuations in serum levels of calciotropic hormones. These changes pose a risk to bone health. The study assessed the short-term (12 and 24 months) effects of RYGB and GS on BMD and calciotropic hormones. PubMed, Embase, and Cochrane Library databases were searched. Analyses considered follow-up (12 and 24 months) with BMD as main outcome at three sites (femoral neck...
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - April 9, 2024 Category: Surgery Authors: Paula Caroline de Almeida Thiago da Rosa Lima Eudes Thiago Pereira Avila Am ílcar Sabino Damazo Source Type: research

Revisiting the association between vitamin D deficiency and active tuberculosis: A prospective case-control study in Taiwan
CONCLUSIONS: VDD is an independent risk factor for incident active TB. Future randomized trials examining the effect of vitamin D supplementation on TB incidence should focus on people with a low BMI or other risk factors to maximize the statistical power.PMID:38594108 | DOI:10.1016/j.jmii.2024.03.005 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - April 9, 2024 Category: Microbiology Authors: Meng-Shiuan Hsu Tzu-Chien Chung Ping-Huai Wang Shih-Lung Cheng Yen-Wen Wu Jung-Cheng Hsu Bing-Hsiean Tzeng Heng-Hsu Lin Chung-Ming Tu Fang-Yeh Chu Chi-Tai Fang Source Type: research

Analysis of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios as inflammatory biomarkers in chronic kidney disease: impact of parathyroidectomy
CONCLUSION: N/L and P/L ratios are not reliable biomarkers of inflammation in SHPT patients undergoing PTX. Uremia, which induces a state of chronic inflammation in dialysis patients, and the use of immunosuppression in kidney transplant recipients are some of the confounding factors that prevent the use of this tool in clinical practice.PMID:38591824 | DOI:10.1590/2175-8239-JBN-2023-0175en (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - April 9, 2024 Category: Urology & Nephrology Authors: Andre Kakinoki Teng Eduardo Jorge Duque Shirley Ferraz Crispilho Wagner Domingues Vanda Jorgetti Luciene M Dos Reis Rosilene M Elias Rosa Maria Affonso Moys és Source Type: research

Revisiting the association between vitamin D deficiency and active tuberculosis: A prospective case-control study in Taiwan
CONCLUSIONS: VDD is an independent risk factor for incident active TB. Future randomized trials examining the effect of vitamin D supplementation on TB incidence should focus on people with a low BMI or other risk factors to maximize the statistical power.PMID:38594108 | DOI:10.1016/j.jmii.2024.03.005 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - April 9, 2024 Category: Microbiology Authors: Meng-Shiuan Hsu Tzu-Chien Chung Ping-Huai Wang Shih-Lung Cheng Yen-Wen Wu Jung-Cheng Hsu Bing-Hsiean Tzeng Heng-Hsu Lin Chung-Ming Tu Fang-Yeh Chu Chi-Tai Fang Source Type: research

Analysis of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios as inflammatory biomarkers in chronic kidney disease: impact of parathyroidectomy
CONCLUSION: N/L and P/L ratios are not reliable biomarkers of inflammation in SHPT patients undergoing PTX. Uremia, which induces a state of chronic inflammation in dialysis patients, and the use of immunosuppression in kidney transplant recipients are some of the confounding factors that prevent the use of this tool in clinical practice.PMID:38591824 | DOI:10.1590/2175-8239-JBN-2023-0175en (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - April 9, 2024 Category: Urology & Nephrology Authors: Andre Kakinoki Teng Eduardo Jorge Duque Shirley Ferraz Crispilho Wagner Domingues Vanda Jorgetti Luciene M Dos Reis Rosilene M Elias Rosa Maria Affonso Moys és Source Type: research

Revisiting the association between vitamin D deficiency and active tuberculosis: A prospective case-control study in Taiwan
CONCLUSIONS: VDD is an independent risk factor for incident active TB. Future randomized trials examining the effect of vitamin D supplementation on TB incidence should focus on people with a low BMI or other risk factors to maximize the statistical power.PMID:38594108 | DOI:10.1016/j.jmii.2024.03.005 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - April 9, 2024 Category: Microbiology Authors: Meng-Shiuan Hsu Tzu-Chien Chung Ping-Huai Wang Shih-Lung Cheng Yen-Wen Wu Jung-Cheng Hsu Bing-Hsiean Tzeng Heng-Hsu Lin Chung-Ming Tu Fang-Yeh Chu Chi-Tai Fang Source Type: research

Analysis of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios as inflammatory biomarkers in chronic kidney disease: impact of parathyroidectomy
CONCLUSION: N/L and P/L ratios are not reliable biomarkers of inflammation in SHPT patients undergoing PTX. Uremia, which induces a state of chronic inflammation in dialysis patients, and the use of immunosuppression in kidney transplant recipients are some of the confounding factors that prevent the use of this tool in clinical practice.PMID:38591824 | DOI:10.1590/2175-8239-JBN-2023-0175en (Source: Jornal Brasileiro de Nefrologia)
Source: Jornal Brasileiro de Nefrologia - April 9, 2024 Category: Urology & Nephrology Authors: Andre Kakinoki Teng Eduardo Jorge Duque Shirley Ferraz Crispilho Wagner Domingues Vanda Jorgetti Luciene M Dos Reis Rosilene M Elias Rosa Maria Affonso Moys és Source Type: research

Safety of cinacalcet in children and adolescents with chronic kidney disease-mineral bone disorder: systematic review and proportional meta-analysis of case series
Conclusions and implications of key findingsIf used in the pediatric population, the calcimimetic cinacalcet should be carefully monitored for serum calcium levels and attention to possible adverse events, especially in children under 50  months.Systematic review registration number (PROSPERO register)CRD42019132809. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - April 9, 2024 Category: Urology & Nephrology Source Type: research

Epidemiological analysis to identify predictors of X-linked hypophosphatemia (XLH) diagnosis in an Italian pediatric population: the EPIX project
ConclusionFindings showed that data-driven machine learning models may play a prominent role for the prediction of the diagnosis of rare diseases such as XLH. (Source: Endocrine)
Source: Endocrine - April 9, 2024 Category: Endocrinology Source Type: research