Secretome of adipose derived-mesenchymal stem cells reduces the < em > Vibrio cholerae < /em > attachment to Caco-2 cells and subsequent inflammatory responses
CONCLUSION: The secretome of AD-MSCs can play a critical role in inhibiting bacterial colonization, and subsequent inflammatory responses, and maintaining the integrity of the epithelial barrier. The secretome may be effective in the prevention of hypovolemic shock.PMID:38682070 | PMC:PMC11055443 | DOI:10.18502/ijm.v16i1.14875 (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - April 29, 2024 Category: Microbiology Authors: Alireza Moulazade Sara Soudi Bita Bakhshi Source Type: research
Efficacy of SARS-CoV-2 Vaccine Doses in Allogeneic Hemopoietic Stem Cell Recipients: Concerns
Asian Pac J Cancer Prev. 2024 Apr 1;25(4):1111. doi: 10.31557/APJCP.2024.25.4.1111.NO ABSTRACTPMID:38679969 | DOI:10.31557/APJCP.2024.25.4.1111 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Hinpetch Daungsupawong Viroj Wiwanitkit Source Type: research
CAVIN1-Mediated hERG Dynamics: A Novel Mechanism Underlying the Interindividual Variability in Drug-Induced Long QT
CONCLUSIONS: Our study identifies unbridled turnover of the potassium channel hERG as a mechanism supporting the interindividual susceptibility underlying diLQT development and demonstrates how this phenomenon is finely tuned by CAVIN1.PMID:38682330 | DOI:10.1161/CIRCULATIONAHA.123.063917 (Source: Circulation)
Source: Circulation - April 29, 2024 Category: Cardiology Authors: Zeina R Al Sayed C éline Pereira R émi Le Borgne Christine Viaris de Lesegno Charl ène Jouve Esthel P énard Adeline Mallet Nihar Masurkar Gildas Loussouarn Jean-Marc Verbavatz Christophe Lamaze David-Alexandre Tr égouët Jean-S ébastien Hulot Source Type: research
The Effect of Tumor Resection and Radiotherapy on the Expression of Stem Cell Markers (CD44 and CD133) in Patients with Squamous Cell Carcinoma
Conclusion: The results also indicated that the expression of CD44 significantly decreased after tumor resection and radiotherapy. The upregulation of mRNA level of Bcl-2 and ALDH, and the downregulation of Bax and Bak gene expression were noted in these cases when compared to the healthy control group.PMID:38680713 | PMC:PMC11055418 | DOI:10.18502/ijhoscr.v18i1.14748 (Source: Cancer Control)
Source: Cancer Control - April 29, 2024 Category: Cancer & Oncology Authors: Ladan Paya Ali Rafat Mehdi Talebi Amirala Aghbali Nikzad Shahidi Babak Nejati Parya Emamverdizadeh Hojjatollah Nozad Charoudeh Source Type: research
Plasma Circulating Terminal Differentiation-Induced Non-Coding RNA Serves as a Biomarker in Breast Cancer
Conclusion: A low level of plasma TINCR could discriminate breast cancer patients from healthy control subjects.PMID:38680708 | PMC:PMC11055416 | DOI:10.18502/ijhoscr.v18i1.14739 (Source: Cancer Control)
Source: Cancer Control - April 29, 2024 Category: Cancer & Oncology Authors: Zeynab Shaghaghi Torkdari Mohammad Khalaj-Kondori Mohammad Ali Hosseinpour Feizi Source Type: research
Role of cancer stem cell ecosystem on breast cancer metastasis and related mouse models
Zool Res. 2024 May 18;45(3):506-517. doi: 10.24272/j.issn.2095-8137.2023.411.ABSTRACTBreast cancer metastasis is responsible for most breast cancer-related deaths and is influenced by many factors within the tumor ecosystem, including tumor cells and microenvironment. Breast cancer stem cells (BCSCs) constitute a small population of cancer cells with unique characteristics, including their capacity for self-renewal and differentiation. Studies have shown that BCSCs not only drive tumorigenesis but also play a crucial role in promoting metastasis in breast cancer. The tumor microenvironment (TME), composed of stromal cells,...
Source: Cell Research - April 29, 2024 Category: Cytology Authors: Xilei Peng Haonan Dong Lixing Zhang Suling Liu Source Type: research
Evaluation of Central Nervous System Relapse in Adults with Acute Lymphoblastic Leukemia (ALL) Receiving Hyper-CVAD Treatment in Seyyed Al-Shohada Hospital: Isfahan, 2014-2019
Conclusion: This study shows that the prognosis of CNS relapse in adults with ALL has not improved much. Limited studies have been conducted on the recurrence of the central nervous system in adults with acute lymphoblastic leukemia. Therefore, further studies on CNS relapse after complete remission of ALL are required to clarify more details.PMID:38680719 | PMC:PMC11055424 | DOI:10.18502/ijhoscr.v18i1.14743 (Source: Cell Research)
Source: Cell Research - April 29, 2024 Category: Cytology Authors: Alireza Sadeghi Reyhane Gardashti Farzaneh Ashrafi Valiollah Mehrzad Source Type: research
Rate, Risk Factors, and Outcomes of Invasive Fungal Infections in Patients with Hematologic Malignancies
Conclusion: IFI represents a frequent complication for HM patients with high mortality. Aspergillus species are the predominant etiology in these settings. Considering our results, in high-risk patients, manifestations of warning signs in the sinus and lungs, which would not be cleared despite receiving antibiotics, should raise the possibility of IFIs.PMID:38680718 | PMC:PMC11055423 | DOI:10.18502/ijhoscr.v18i1.14746 (Source: Cell Research)
Source: Cell Research - April 29, 2024 Category: Cytology Authors: Shirin Afhami Alireza Adibimehr Seyed Asadollah Mousavi Mohammad Vaezi Mahnaz Montazeri Mohammadreza Salehi Mohsen Meidani Mahshid Saleh Kazem Ahmadikia Emmanuel Roilides Johan Maertens Neda Alijani Source Type: research
Lymphocyte Level at Diagnosis in Hodgkin lymphoma: Could It be an Indicator of the Stage at Initial Diagnosis?
Conclusion: This result can be improved in combination with conventional imaging methods used for staging purposes. Further studies may shed light on staging and especially the diagnosis of advanced-stage disease with high sensitivity.PMID:38680717 | PMC:PMC11055420 | DOI:10.18502/ijhoscr.v18i1.14741 (Source: Cell Research)
Source: Cell Research - April 29, 2024 Category: Cytology Authors: Hasan Goze Tahir Alper Cinli Kursad Nuri Baydilli Istemi Serin Source Type: research
Kinetics of Recovery of Naive and Memory T Cells in Acute Leukemia Patients after Allogeneic Stem Cell Transplantation Depending on Different GVHD Prophylaxis Regimens
Conclusion: These experimental outcomes contribute to providing the best understanding of immunological events that occur early after transplantation and help in the rational choice of GVHD prophylaxis in patients who will undergo allogeneic transplantation. Our study demonstrated the comparable immunological effects of posttransplant cyclophosphamide and ex vivo T cell depletion and immunological inefficiency of horse ATG for GVHD prevention.PMID:38680716 | PMC:PMC11055426 | DOI:10.18502/ijhoscr.v18i1.14742 (Source: Cell Research)
Source: Cell Research - April 29, 2024 Category: Cytology Authors: Natalia Popova Mikhail Drokov Yulia Davydova Nikolay Kapranov Vera Vasilieva Irina Galtseva Larisa Kuzmina Elena Parovichnikova Source Type: research
Fludarabine-Based Reduced-Intensity Conditioning Regimen for Hematopoietic Stem Cell Transplantation in a Pediatric Patient with Sickle Cell Disease: A Case Report
Int J Hematol Oncol Stem Cell Res. 2024 Jan 1;18(1):104-109. doi: 10.18502/ijhoscr.v18i1.14750.ABSTRACTReduced-intensity conditioning (RIC) regimens have the potential to decrease toxicities related to hematopoietic stem cell transplantation (HCT) in patients with sickle cell disease (SCD). While initial results may have been acceptable in adults and young adults, there are no well-established strategies in children with SCD. Here, it is described the clinical course of two children with symptomatic SCD who have successfully undergone HSCT using Fludarabin-based conditioning.PMID:38680715 | PMC:PMC11055425 | DOI:10.18502/i...
Source: Cell Research - April 29, 2024 Category: Cytology Authors: Natalia Builes Source Type: research
Plasma Circulating Terminal Differentiation-Induced Non-Coding RNA Serves as a Biomarker in Breast Cancer
Conclusion: A low level of plasma TINCR could discriminate breast cancer patients from healthy control subjects.PMID:38680708 | PMC:PMC11055416 | DOI:10.18502/ijhoscr.v18i1.14739 (Source: Cell Research)
Source: Cell Research - April 29, 2024 Category: Cytology Authors: Zeynab Shaghaghi Torkdari Mohammad Khalaj-Kondori Mohammad Ali Hosseinpour Feizi Source Type: research
The Importance of Pseudo Thrombocytopenia Due to Platelet Cold Agglutination before Surgery, What Should We Do? A Case Report
Int J Hematol Oncol Stem Cell Res. 2024 Jan 1;18(1):100-103. doi: 10.18502/ijhoscr.v18i1.14749.ABSTRACTPlatelet cold agglutination (PCA) is a rare in-vitro phenomenon caused by Immunoglobulin M (IgM) autoantibodies, which results in Ethylenediaminetetraacetic Acid (EDTA) independent pseudo thrombocytopenia (PTCP). Its diagnosis is made based on the peripheral blood smear (PBS) examination and pre-test warming blood sample. Here, a case of PTCP secondary to PCA is presented. He was first admitted for pre-surgical tests but his platelet count was low. His blood was taken with EDTA and sodium citrate anticoagulant to rule pre...
Source: Cell Research - April 29, 2024 Category: Cytology Authors: Mohammad Ghorbani Amin Solouki Farhang Soltani Amir Moayedpour Zahra Khoshnegah Source Type: research
Thrombocytopenia Secondary to COVID-19: Outcomes Analysis in Terms of Thrombotic Microangiopathy, Acute Kidney Injury, and Mortality
Conclusion: We outlined TMA in COVID-19 patients, which could be responsible for kidney injury and mortality in critically COVID-19 patients.PMID:38680710 | PMC:PMC11055419 | DOI:10.18502/ijhoscr.v18i1.14740 (Source: Cell Research)
Source: Cell Research - April 29, 2024 Category: Cytology Authors: Bahareh Gheiasi Fakhredin Taghinezhad Darshik Kumar Patel Ebrahim Salimi Mashallah Babashahi Aliashraf Mozafari Source Type: research
Results of Autologous Hematopoietic Stem Cell Transplantation in Patients with Multiple Myeloma(MM) and Renal Impairment: A Retrospective Single-Center Study
Conclusion: Auto-HSCT is a safe and effective treatment for patients with MM complicated by acute kidney injury. Fourteen of 23 (61%) patients became dialysis-independent.PMID:38680711 | PMC:PMC11055427 | DOI:10.18502/ijhoscr.v18i1.14745 (Source: Cell Research)
Source: Cell Research - April 29, 2024 Category: Cytology Authors: Maiia Soloveva Maxim Solovev Daria Mironova Larisa Mendeleeva Source Type: research
