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Condition: Ataxia

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Total 492 results found since Jan 2013.

Wall-Eyed Bilateral Internuclear Ophthalmoplegia by Ischemic Stroke: Case Report and Literature Review
Conclusion: Gaze-evoked upward nystagmus on upward gaze and bilateral limb ataxia accompanied by WEBINO due to a small brainstem lesion were the characteristic findings of our case.
Source: The Neurologist - May 1, 2020 Category: Neurology Tags: Case Report/Case Series Source Type: research

A middle-aged man presenting with progressive ataxia and pendular nystagmus: a delayed onset post-stroke movement disorder
Source: Acta Neurologica Belgica - April 19, 2020 Category: Neurology Source Type: research

Dupilumab for Atopic Dermatitis, a Possible Risk Factor of Juvenile Ischemic Stroke: A Case Report
We report the case of a 20-year-old man with atopic dermatitis treated with dupilumab for half a year, who presented with sudden onset of dizziness, nausea, and slight cerebellar ataxia. Brain magnetic resonance imaging revealed acute infarction in the bicerebellar hemispheres.
Source: Journal of Stroke and Cerebrovascular Diseases - April 3, 2020 Category: Neurology Authors: Ryo Iwase, Taro Ishiguro, Kyohei Fujita, Satoru Ishibashi, Takanori Yokota Source Type: research

A Case of Creutzfeldt-Jakob Disease with Stroke-Like Onset
Creutzfeldt-Jakob disease (CJD) is a prion disease characterized by rapidly progressive dementia that is often followed by behavioral disturbances, ataxia, myoclonus, and akinetic mutism. The initial symptoms of CJD reportedly vary, but the onset is usually gradual. Here, we report a case of CJD with a sudden, stroke-like onset of right hemiparesis to alert readers that CJD can mimic a stroke during its early stage.
Source: Journal of Stroke and Cerebrovascular Diseases - March 27, 2020 Category: Neurology Authors: Kosuke Okamoto, Takato Abe, Yoshiaki Itoh Tags: Case Report Source Type: research

Can emergency physicians accurately rule out a central cause of vertigo using the HINTS exam? A systematic review and meta-analysis.
CONCLUSIONS: The HINTS exam when used in isolation by emergency physicians has not been shown to be sufficiently accurate to rule out a stroke in those presenting with AVS. PMID: 32167642 [PubMed - as supplied by publisher]
Source: Accident and Emergency Nursing - March 12, 2020 Category: Emergency Medicine Authors: Ohle R, Montpellier RA, Marchadier V, Wharton A, McIsaac S, Anderson M, Savage D Tags: Acad Emerg Med Source Type: research

WEBINO syndrome (wall-eyed bilateral internuclear ophthalmoplegia) secondary to ischemic stroke, about a case.
We present the case of a 68 year-old man who was initially attended in emergency department with sudden onset diplopia. Neurological exploration revealed WEBINO and gait ataxia. Relevant medical history included liver transplantation and subsequent tacrolimus prescription. Complementary exams revealed ischemic lesion in mesencephalic tegmentum, involving medial longitudinal fasciculus and pretectal area. WEBINO syndrome is unfrequent. Among its etiologies, ischemic and demyelinating are the most frequent. In our case, iatrogenic etiology was also considered. Clinical recognition of this syndrome is required to perform adeq...
Source: Archivos de la Sociedad Espanola de Oftalmologia - February 24, 2020 Category: Opthalmology Tags: Arch Soc Esp Oftalmol Source Type: research

Miller Fisher syndrome with bilateral vocal cord paralysis: a case report
ConclusionThe occurrence of acute or subacute descending paralysis with involvement of bulbar muscles and respiratory failure can often divert clinicians to a diagnosis of neuromuscular junction disorders (such as botulism or myasthenia gravis), vascular causes like stroke, or electrolyte and metabolic abnormalities. Early identification of Miller Fisher syndrome with appropriate testing is essential to prompt treatment and prevention of further, potentially fatal, deterioration.
Source: Journal of Medical Case Reports - February 17, 2020 Category: General Medicine Source Type: research

Relationship between ataxia and inferior cerebellar peduncle injury in patients with cerebral infarct
In this study, using diffusion tensor tractography (DTT), we investigated the relationship between ataxia and ICP injury in patients with cerebral infarct. Methods: We recruited 14 stroke patients with ataxia after the onset of stroke and 12 normal subjects. The Score of Assessment and Rating of Ataxia (SARA) was used to evaluate ataxia. The values of fractional anisotropy (FA), apparent diffusion coefficient, and fiber number (FN) of the ICP were measured for the diffusion tensor imaging parameters. Results: Significant differences were observed in the FA and FN values of the ICP in the affected hemisphere between t...
Source: Medicine - February 1, 2020 Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research

Patient-Friendly Summary of the ACR Appropriateness Criteria: Ataxia
Ataxia is the loss of control of bodily movement due to impairment in the nervous system. The patient may have a wide-based, unsteady walk or poor coordination of the arms and legs. Ataxia may be caused by a problem in the cerebellum (the part of the brain that controls coordination), the spinal cord and nerves (which control body movement), or the inner ear vestibular system (which maintains balance). Ataxia can also be caused by a stroke. The appropriate imaging of ataxia depends on the suspected cause.
Source: Journal of the American College of Radiology : JACR - January 29, 2020 Category: Radiology Authors: Susan Anemone, Nina S. Vincoff Tags: Appropriate use criteria Source Type: research

Stroke-like episodes in OPA1 carriers require comprehensive work-up and therapeutic considerations
AbstractThis is a letter to the Editor concerning the recently published article by Zerem et al. The paper described a 12yo female with multisystem mitochondrial disorder (MID) due to the compound heterozygous variants c.1963_1964dupAT and p.Ile382Met inOPA1 manifesting phenotypically with congenital nystagmus, developmental delay, visual impairment, gait ataxia, epilepsy, a stroke-like episode (SLE) with encephalopathy and vomiting, and hearing impairment. This interesting case could be more meaningful by providing more information about the treatment of the SLE/stroke-like lesion (SLL), about the morphological characteri...
Source: Metabolic Brain Disease - January 23, 2020 Category: Neurology Source Type: research

Metabolic Stroke: A Novel Presentation in a Child with Succinic Semialdehyde Dehydrogenase Deficiency
Sangeetha Yoganathan, Gautham Arunachal, Lisa Kratz, Mugil Varman, Maya Thomas, Sniya Valsa Sudhakar, Samuel Philip Oommen, Sumita DandaAnnals of Indian Academy of Neurology 2020 23(1):113-117 Succinic semialdehyde dehydrogenase (SSADH) deficiency is an autosomal recessive disorder of gamma-aminobutyric acid metabolism. Children with SSADH deficiency usually manifest with developmental delay, behavioral symptoms, language dysfunction, seizures, hypotonia, extrapyramidal symptoms, and ataxia. Diagnosis of SSADH deficiency is established by an abnormal urine organic acid pattern, including increased excretion of 4-hydroxybu...
Source: Annals of Indian Academy of Neurology - January 20, 2020 Category: Neurology Authors: Sangeetha Yoganathan Gautham Arunachal Lisa Kratz Mugil Varman Maya Thomas Sniya Valsa Sudhakar Samuel Philip Oommen Sumita Danda Source Type: research

Cervical Posterior Spinal Artery Syndrome Caused By Spontaneous Vertebral Artery Dissection: Two Case Reports and Literature Review
Herein, we described 2 patients with posterior spinal artery syndrome (PSAS) caused by vertebral artery dissection. The patients complained of sudden neck pain or walking instability. Neurological examination revealed sensory loss, muscle weakness, and sensory ataxia. Angiography showed double lumen sign or intimal flap in the vertebral artery. T2-weighted imaging and diffusion-weighted imaging of MRI showed a hyperintense lesion in the dorsal side of the cervical spinal cord at different times after onset.
Source: Journal of Stroke and Cerebrovascular Diseases - January 12, 2020 Category: Neurology Authors: Futao Chen, Xuemeng Liu, Tiantian Qiu, Chunxue Jia, Min Liu, Qianxiu Jin, Peihong Gao, Xiaodong Li Tags: Case Report Source Type: research

Multitarget deep brain stimulation for clinically complex movement disorders.
Abstract Deep brain stimulation (DBS) of single-target nuclei has produced remarkable functional outcomes in a number of movement disorders such as Parkinson's disease, essential tremor, and dystonia. While these benefits are well established, DBS efficacy and strategy for unusual, unclassified movement disorder syndromes is less clear. A strategy of dual pallidal and thalamic electrode placement is a rational approach in such cases where there is profound, medically refractory functional impairment. The authors report a series of such cases: midbrain cavernoma hemorrhage with olivary hypertrophy, spinocerebellar ...
Source: Journal of Neurosurgery - January 2, 2020 Category: Neurosurgery Authors: Parker T, Raghu ALB, FitzGerald JJ, Green AL, Aziz TZ Tags: J Neurosurg Source Type: research

Intravenous Thrombolysis at 3.5 Hours From Onset of Pediatric Acute Ischemic Stroke
We report the case of a 14-year-old girl who presented with right-sided weakness and ataxia, loss of sensation, and altered mental status. Magnetic resonance imaging with diffusion-weighted imaging showed an acute lesion in the distribution of the left posterior cerebral artery, and magnetic resonance angiogram demonstrated occlusion of the third branch of the left posterior cerebral artery. With parental consent, clinicians decided to infuse an adult dose of weight-adjusted intravenous alteplase at 3.5 hours from onset of symptoms, with subsequent improvement in National Institutes of Health Stroke Scale score from 11 to ...
Source: Pediatric Emergency Care - January 1, 2020 Category: Emergency Medicine Tags: Illustrative Cases Source Type: research

Normal Pressure Hydrocephalus: Clinical Symptoms, Cerebrospinal Fluid Flow Metrics and White Matter Changes
Conclusions Patients with NPH, regardless of stages of the diseases, have increased ASV values and could benefit from shunting. Decreasing ASV values of patients with FG 3 comparing with those with FG 2 support the hypothesis of decreasing compliance of brain with aging and increasing severity of small-vessel disease.
Source: Journal of Computer Assisted Tomography - January 1, 2020 Category: Radiology Tags: Neuroradiology Source Type: research