Composition and organization of the sagittal stratum in the human brain: a fiber dissection study.
CONCLUSIONS: A general model of sagittal stratum organization in layers is possible, but the composition of the external layer is much more complex than is mentioned in classic descriptions. A small contribution of the inferior longitudinal fasciculus is the main difference between the present results and the classic descriptions in which this bundle was considered to entirely correspond to the stratum sagittale externum. This subject has important implications both for fundamental research and neurosurgery, as well as for the development of surgical approaches for the cerebral parenchyma and ventricular system. PMID:...
Source: Journal of Neurosurgery - January 8, 2021 Category: Neurosurgery Authors: Maldonado IL, Destrieux C, Ribas EC, Siqueira de Abreu Brito Guimarães B, Cruz PP, Duffau H Tags: J Neurosurg Source Type: research

Effects of ventricular entry on patient outcome during glioblastoma resection.
Abstract OBJECTIVE: Tumor proximity to the ventricle and ventricular entry (VE) during surgery have both been associated with worse prognoses; however, the interaction between these two factors is poorly understood. Given the benefit of maximal tumor resection, it is imperative for surgical planning and technique to know if VE has negative consequences for patient survival and tumor dissemination. METHODS: The University of California, San Francisco tumor registry was searched for patients with newly diagnosed and recurrent supratentorial glioblastoma (GBM) who underwent resection by the senior author between...
Source: Journal of Neurosurgery - January 8, 2021 Category: Neurosurgery Authors: Young JS, Gogos AJ, Pereira MP, Morshed RA, Li J, Barkovich MJ, Hervey-Jumper SL, Berger MS Tags: J Neurosurg Source Type: research

Letter to the Editor. The COVID-19 crisis and return to the Hippocratic Corpus.
PMID: 33418532 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - January 8, 2021 Category: Neurosurgery Authors: Kurimoto M Tags: J Neurosurg Source Type: research

The role of cell-free DNA in fibrinolysis for intraventricular hemorrhage.
Abstract OBJECTIVE: Tissue plasminogen activator (tPA) fibrinolysis did not improve functional outcomes of patients with intraventricular hemorrhage (IVH), largely because of the unsatisfactory clot clearance. The presence of neutrophil extracellular traps (NETs) within the clot has been confirmed to impair tPA fibrinolysis, but the mechanism has been unclear. The authors hypothesized that cell-free DNA (cfDNA), the main framework of NETs, might be the important reason for the fibrinolysis resistance, and they validated the hypothesis, hoping to provide a new target to promote intraventricular fibrinolysis. M...
Source: Journal of Neurosurgery - January 8, 2021 Category: Neurosurgery Authors: Xie F, Tan Q, Yu A, Guo P, Wang L, Zeng Z, Liang L, Xian J, Feng H, Chen Z Tags: J Neurosurg Source Type: research

Deciphering the frontostriatal circuitry through the fiber dissection technique: direct structural evidence on the morphology and axonal connectivity of the fronto-caudate tract.
CONCLUSIONS: By using the fiber microdissection technique, the authors provide sound structural evidence on the topography, morphology, and connectional anatomy of the FCT as a distinct part of a wider frontostriatal circuitry. The findings are in line with the tract's putative functional implications in high-order motor and behavioral processes and can potentially inform current surgical practice in the fields of neuro-oncology and functional neurosurgery. PMID: 33385993 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - January 1, 2021 Category: Neurosurgery Authors: Komaitis S, Koutsarnakis C, Lani E, Kalamatianos T, Drosos E, Skandalakis GP, Liakos F, Liouta E, Kalyvas AV, Stranjalis G Tags: J Neurosurg Source Type: research

Postoperative recurrence of chronic subdural hematoma is more frequent in patients with blood type A.
CONCLUSIONS: The study results showed that blood type A is an independent risk factor for the postoperative recurrence of CSDH and that careful follow-up in these patients may be needed. PMID: 33385994 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - January 1, 2021 Category: Neurosurgery Authors: Hirai S, Yagi K, Hara K, Kanda E, Matsubara S, Uno M Tags: J Neurosurg Source Type: research

Stereotactic radiosurgery for treatment of radiation-induced meningiomas: a multiinstitutional study.
CONCLUSIONS: SRS is associated with durable local control of RIMs in the majority of patients and has an acceptable safety profile. SRS can be considered for patients and tumors that are deemed suboptimal, poor surgical candidates, and those whose tumor again progresses after removal. PMID: 33385995 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - January 1, 2021 Category: Neurosurgery Authors: Bunevicius A, Suleiman M, Patel S, Martínez Álvarez R, Martinez Moreno NE, Liscak R, Hanuska J, Langlois AM, Mathieu D, Mau C, Caldwell C, Tuanquin LC, Zacharia BE, McInerney J, Lee CC, Yang HC, Peterson JL, Trifiletti DM, Ogino A, Kano H, Warnick RE, S Tags: J Neurosurg Source Type: research

Basal ganglia cavernous malformations: case series and systematic review of surgical management and long-term outcomes.
Abstract OBJECTIVE: Reports on basal ganglia cavernous malformations (BGCMs) are rare. Here, the authors report on their experience in resecting these malformations to offer insight into this infrequent disease subtype. METHODS: The authors retrospectively reviewed a prospectively managed departmental database of all deep-seated cerebral cavernous malformations (CCMs) treated at Stanford between 1987 and 2019 and included for further analysis those with a radiographic diagnosis of BGCM. Moreover, a systematic literature review was undertaken using the PubMed and Web of Science databases. RESULTS: The dep...
Source: Journal of Neurosurgery - January 1, 2021 Category: Neurosurgery Authors: Li Y, Khahera A, Kim J, Mandel M, Han SS, Steinberg GK Tags: J Neurosurg Source Type: research

Genetic and heritable considerations in patients or families with both intracranial and extracranial aneurysms.
PMID: 33386011 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - January 1, 2021 Category: Neurosurgery Authors: Huguenard AL, Gupta VP, Braverman AC, Dacey RG Tags: J Neurosurg Source Type: research

Development of cerebral microbleeds in patients with cerebral hyperperfusion following carotid endarterectomy and its relation to postoperative cognitive decline.
Abstract OBJECTIVE: A primary cause of cognitive decline after carotid endarterectomy (CEA) is cerebral injury due to cerebral hyperperfusion. However, the mechanisms of how cerebral hyperperfusion induces cerebral cortex and white matter injury are not known. The presence of cerebral microbleeds (CMBs) on susceptibility-weighted imaging (SWI) is independently associated with a decline in global cognitive function. The purpose of this prospective observational study was to determine whether cerebral hyperperfusion following CEA leads to the development of CMBs and if postoperative cognitive decline is related to t...
Source: Journal of Neurosurgery - January 1, 2021 Category: Neurosurgery Authors: Igarashi S, Ando T, Takahashi T, Yoshida J, Kobayashi M, Yoshida K, Terasaki K, Fujiwara S, Kubo Y, Ogasawara K Tags: J Neurosurg Source Type: research

Association between flat-panel computed tomography hyperattenuation and clinical outcome after successful recanalization by endovascular treatment.
Abstract OBJECTIVE: Hyperattenuation on CT scanning performed immediately after endovascular treatment (EVT) is known to be associated with the final infarct. As flat-panel CT (FPCT) scanning is readily accessible within their angiography suite, the authors evaluated the ability of the extent of hyperattenuation on FPCT to predict clinical outcomes after EVT. METHODS: Patients with successful recanalization (modified Thrombolysis in Cerebral Infarction grade 2b or 3) were reviewed retrospectively. The extent of hyperattenuation was assessed by the Alberta Stroke Program Early CT Score on FPCT (FPCT-ASPECTS). ...
Source: Journal of Neurosurgery - December 25, 2020 Category: Neurosurgery Authors: Baek JH, Kim BM, Heo JH, Kim DJ, Nam HS, Kim YD, Choi HS, Kim JH, Kim JW Tags: J Neurosurg Source Type: research

Letter to the Editor. Zero complications in SEEG: a goal to pursue.
PMID: 33361478 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - December 25, 2020 Category: Neurosurgery Authors: Rizzi M, Castana L, d'Orio P, Cardinale F Tags: J Neurosurg Source Type: research

Outcomes following surgical management of vagus nerve stimulator-related infection: a retrospective multi-institutional study.
CONCLUSIONS: Removal of the VNS including electrode leads combined with antibiotic administration is the definitive treatment but has a risk of causing dysphagia. If the surgeon finds dense scarring around the vagus nerve, the prudent approach is to snip the electrode close to the nerve as opposed to attempting to unwind the lead completely. PMID: 33339002 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - December 18, 2020 Category: Neurosurgery Authors: Hasegawa H, Van Gompel JJ, Marsh WR, Wharen RE, Zimmerman RS, Burkholder DB, Lundstrom BN, Britton JW, Meyer FB Tags: J Neurosurg Source Type: research

Intracranial EEG and laser interstitial thermal therapy in MRI-negative insular and/or cingulate epilepsy: case series.
CONCLUSIONS: sEEG can be safely used to localize seizures originating from insular and cingulate cortex. LITT can successfully treat seizures arising from these deep-seated structures. The insula and cingulum should be evaluated more frequently for seizure onset zones. PMID: 33307521 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - December 11, 2020 Category: Neurosurgery Authors: Gireesh ED, Lee K, Skinner H, Seo J, Chen PC, Westerveld M, Beegle RD, Castillo E, Baumgartner J Tags: J Neurosurg Source Type: research

Resident evaluations in the age of competency-based medical education: faculty perspectives on minimizing burdens.
CONCLUSIONS: To facilitate the successful implementation of CBME into a neurosurgical training curriculum, resident EPA assessment forms should take 3 minutes or less to complete and be accessible through a mobile application. PMID: 33307525 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - December 11, 2020 Category: Neurosurgery Authors: Rabski JE, Saha A, Cusimano MD Tags: J Neurosurg Source Type: research

Optimal access route for pontine cavernous malformation resection with preservation of abducens and facial nerve function.
CONCLUSIONS: The authors' results suggest favoring a posterolateral over a posteromedial access route to PCMs in patients in whom a lesion is encountered that can be removed via either surgical approach. In the present series, the authors have found such a constellation in 57% of all patients. This retrospective analysis confirms their hypothesis in a large patient cohort. Additionally, the authors demonstrated that 4 types of PCMs can be distinguished by preoperatively evaluating whether only one reasonable or two alternative surgical approaches are available to access a specific lesion. The rates of postoperative sixth a...
Source: Journal of Neurosurgery - December 11, 2020 Category: Neurosurgery Authors: Bertalanffy H, Ichimura S, Kar S, Tsuji Y, Huang C Tags: J Neurosurg Source Type: research

Stereotactic radiosurgery with versus without prior Onyx embolization for brain arteriovenous malformations.
CONCLUSIONS: Pre-SRS AVM embolization with Onyx does not appear to negatively influence outcomes after SRS. These analyses, based on de novo nidal characteristics, thereby refute previous studies that found detrimental effects of Onyx embolization on SRS-induced AVM obliteration. However, given the risks incurred by nidal embolization using Onyx, this neoadjuvant intervention should be used judiciously in multimodal treatment strategies involving SRS for appropriately selected large-volume or angioarchitecturally high-risk AVMs. PMID: 33307527 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - December 11, 2020 Category: Neurosurgery Authors: Chen CJ, Ding D, Lee CC, Kearns KN, Pomeraniec IJ, Cifarelli CP, Arsanious DE, Liscak R, Hanuska J, Williams BJ, Yusuf MB, Woo SY, Ironside N, Burke RM, Warnick RE, Trifiletti DM, Mathieu D, Mureb M, Benjamin C, Kondziolka D, Feliciano CE, Rodriguez-Merca Tags: J Neurosurg Source Type: research

Internal dose escalation associated with increased local control for melanoma brain metastases treated with stereotactic radiosurgery.
Abstract OBJECTIVE: The internal high-dose volume varies widely for a given prescribed dose during stereotactic radiosurgery (SRS) to treat brain metastases (BMs). This may be altered during treatment planning, and the authors have previously shown that this improves local control (LC) for non-small cell lung cancer BMs without increasing toxicity. Here, they seek to identify potentially actionable dosimetric predictors of LC after SRS for melanoma BM. METHODS: The records of patients with unresected melanoma BM treated with single-fraction Gamma Knife RS between 2006 and 2017 were reviewed. LC was assessed o...
Source: Journal of Neurosurgery - December 11, 2020 Category: Neurosurgery Authors: Kennedy WR, DeWees TA, Acharya S, Mahmood M, Knutson NC, Goddu SM, Kavanaugh JA, Mitchell TJ, Rich KM, Kim AH, Leuthardt EC, Dowling JL, Dunn GP, Chicoine MR, Perkins SM, Huang J, Tsien CI, Robinson CG, Abraham CD Tags: J Neurosurg Source Type: research

Efficacy of decitabine in malignant meningioma cells: relation to promoter demethylation of distinct tumor suppressor and oncogenes and independence from TERT.
CONCLUSIONS: Decitabine decreases proliferation and viability in high-grade but not in benign meningioma cell lines. The effects of decitabine are TERT independent but related to DNA methylation changes of promoters of distinct tumor suppressor genes and oncogenes. PMID: 33307532 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - December 11, 2020 Category: Neurosurgery Authors: Stögbauer L, Thomas C, Wagner A, Warneke N, Bunk EC, Grauer O, Canisius J, Paulus W, Stummer W, Senner V, Brokinkel B Tags: J Neurosurg Source Type: research

Holmes tremor: a delayed complication after resection of brainstem cavernomas.
Abstract OBJECTIVE: In this paper, the authors aimed to illustrate how Holmes tremor (HT) can occur as a delayed complication after brainstem cavernoma resection despite strict adherence to the safe entry zones (SEZs). METHODS: After operating on 2 patients with brainstem cavernoma at the Great Metropolitan Hospital Niguarda in Milan and noticing a similar pathological pattern postoperatively, the authors asked 10 different neurosurgery centers around the world to identify similar cases, and a total of 20 were gathered from among 1274 cases of brainstem cavernomas. They evaluated the tremor, cavernoma locatio...
Source: Journal of Neurosurgery - December 11, 2020 Category: Neurosurgery Authors: Cenzato M, Colistra D, Iacopino G, Raftopoulos C, Sure U, Tatagiba M, Spetzler RF, Konovalov AN, Smolanka A, Smolanka V, Stefini R, Bortolotti C, Ferroli P, Pinna G, Franzini A, Dammann P, Naros G, Boeris D, Mantovani P, Lizio D, Piano M, Fava E Tags: J Neurosurg Source Type: research

Neuropsychological assessments before and after awake surgery for incidental low-grade gliomas.
Abstract OBJECTIVE: Early surgery in presumed asymptomatic patients with incidental low-grade glioma (ILGG) has been suggested to improve maximal resection rates and overall survival. However, no study has reported on the impact of such preventive treatment on cognitive functioning. The aim of this study was to investigate neuropsychological outcomes in patients with ILGG who underwent preventive surgery. METHODS: This was a retrospective analysis of a consecutive series of patients with ILGG who underwent awake surgery and who had presurgical and 3-month postsurgical neuropsychological assessments. Data were...
Source: Journal of Neurosurgery - December 4, 2020 Category: Neurosurgery Authors: Ng S, Herbet G, Lemaitre AL, Cochereau J, Moritz-Gasser S, Duffau H Tags: J Neurosurg Source Type: research

Letter to the Editor. The COVID-19 pandemic and the inequities of the neurosurgery match.
PMID: 33276334 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - December 4, 2020 Category: Neurosurgery Authors: White MD, Fox BM, Agarwal N Tags: J Neurosurg Source Type: research

Letter to the Editor. Intracranial pressure monitoring: challenge beyond the threshold numerical value.
eri G PMID: 33276335 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - December 4, 2020 Category: Neurosurgery Authors: Nunes Rabelo N, Gonçalves de Sena Barbosa M, Pereira Silva Lemos M, Brasil S, Frigieri G Tags: J Neurosurg Source Type: research

Outcomes of stereotactic radiosurgery for hemorrhagic arteriovenous malformations with or without prior resection or embolization.
In this study, the authors aimed to clarify the role of SRS for rAVM as a stand-alone modality and an adjunct for a remnant nidus after surgery or embolization. METHODS: Data on 410 consecutive patients with rAVMs treated with SRS were analyzed. The patients were classified into groups, according to prior interventions: SRS-alone, surgery and SRS (Surg-SRS), and embolization and SRS (Embol-SRS) groups. The outcomes of the SRS-alone group were analyzed in comparison with those of the other two groups. RESULTS: The obliteration rate was higher in the Surg-SRS group than in the SRS-alone group (5-year cumulative rate 97% vs 79%, p
Source: Journal of Neurosurgery - December 4, 2020 Category: Neurosurgery Authors: Kawashima M, Hasegawa H, Shin M, Shinya Y, Ishikawa O, Koizumi S, Katano A, Nakatomi H, Saito N Tags: J Neurosurg Source Type: research

Clinical and genomic factors associated with seizures in meningiomas.
Abstract OBJECTIVE: The association of seizures with meningiomas is poorly understood. Moreover, any relationship between seizures and the underlying meningioma genomic subgroup has not been studied. Herein, the authors report on their experience with identifying clinical and genomic factors associated with preoperative and postoperative seizure presentation in meningioma patients. METHODS: Clinical and genomic sequencing data on 394 patients surgically treated for meningioma at Yale New Haven Hospital were reviewed. Correlations between clinical, histological, or genomic variables and the occurrence of preop...
Source: Journal of Neurosurgery - December 4, 2020 Category: Neurosurgery Authors: Gupte TP, Li C, Jin L, Yalcin K, Youngblood MW, Miyagishima DF, Mishra-Gorur K, Zhao AY, Antonios J, Huttner A, McGuone D, Blondin NA, Contessa JN, Zhang Y, Fulbright RK, Gunel M, Erson-Omay Z, Moliterno J Tags: J Neurosurg Source Type: research

The mediums of dissemination of knowledge and illustration in neurosurgery: unraveling the evolution.
Abstract The earliest evidence of man's attempts in communicating ideas and emotions can be seen on cave walls and ceilings from the prehistoric era. Ingenuity, as well as the development of tools, allowed clay tablets to become the preferred method of documentation, then papyrus and eventually the codex. As civilizations advanced to develop structured systems of writing, knowledge became a power available to only those who were literate. As the search to understand the intricacies of the human brain moved forward, so did the demand for teaching the next generation of physicians. The different methods of distribut...
Source: Journal of Neurosurgery - December 4, 2020 Category: Neurosurgery Authors: Raju B, Jumah F, Narayan V, Sonig A, Sun H, Nanda A Tags: J Neurosurg Source Type: research

Erratum. Triple motor mapping: transcranial, bipolar, and monopolar mapping for supratentorial glioma resection adjacent to motor pathways.
PMID: 33254131 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 27, 2020 Category: Neurosurgery Authors: Gogos AJ Tags: J Neurosurg Source Type: research

The surgical history of head injury in motor vehicle collision.
Abstract Motor vehicle collisions (MVCs) are a significant cause of head injuries today, but efforts to manage and prevent these injuries extend as far back as the beginning of modern neurosurgery itself. Head trauma in MVCs occurred as far back as 1899, and the surgical literature of the time mentions several cases of children being struck by passing automobiles. By the 1930s, Dr. Claire L. Straith, a Detroit plastic surgeon, recommended changes to automobile design after seeing facial injuries and depressed skull fractures that resulted from automobile accidents. During World War II, Sir Hugh Cairns, a British n...
Source: Journal of Neurosurgery - November 27, 2020 Category: Neurosurgery Authors: Matur AV, Ngwenya LB, Prestigiacomo CJ Tags: J Neurosurg Source Type: research

Recurrent brainstem cavernous malformations following primary resection: blind spots, fine lines, and the right-angle method.
CONCLUSIONS: The 6.6% rate of BSCM recurrence requiring reoperation reflects the fine lines between complete resection and recurrence and between safe and harmful surgery. The detection of remnants is difficult postoperatively and remains so even at 6 months when the resection bed has healed. The 5.9% annual hemorrhage risk associated with recurrent BSCM in this experience is consistent with that reported for unoperated BSCMs. The right-angle method helps to anticipate blind spots and meticulously inspect the resection cavity for residual BSCM during surgery. A low percentage of recurrent BSCM (5%-10%) ensures ongoing effo...
Source: Journal of Neurosurgery - November 20, 2020 Category: Neurosurgery Authors: Garcia RM, Oh T, Cole TS, Hendricks BK, Lawton MT Tags: J Neurosurg Source Type: research

Divergence in the epidemiological estimates of traumatic brain injury in the United States: comparison of two national databases.
CONCLUSIONS: The databases disagreed widely in their weighted estimates of TBI incidence: CDC estimates were consistently higher than NTDB NSP estimates, by an average of 448%. Although such a discrepancy may be intuitive, this is the first study to quantify the magnitude of disagreement between these databases. Given that research, funding, and policy decisions are made based on these estimates, there is a need for a more accurate estimate of the true national incidence of TBI. PMID: 33254146 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 20, 2020 Category: Neurosurgery Authors: Stopa BM, Harary M, Jhun R, Job A, Izzy S, Smith TR, Gormley WB Tags: J Neurosurg Source Type: research

Does double-blind peer review impact gender authorship trends? An evaluation of two leading neurosurgical journals from 2010 to 2019.
CONCLUSIONS: This is the first report of female authorship in the neurosurgical literature. The authors found that single- versus double-blind peer review did not impact female authorship rates at two top neurosurgical journals. PMID: 33186905 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2020 Category: Neurosurgery Authors: Mahajan UV, Wadhwa H, Fatemi P, Xu S, Shan J, Benzil DL, Zygourakis CC Tags: J Neurosurg Source Type: research

The role of indocyanine green fluorescence in endoscopic endonasal skull base surgery and its imaging correlations.
CONCLUSIONS: Defining the indications and understanding the limitations are critical for the effective use of E-ICG. Tumor fluorescence seems to correlate with preoperative MRI contrast enhancement. PMID: 33186906 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2020 Category: Neurosurgery Authors: Shahein M, Prevedello DM, Beaumont TL, Ismail K, Nouby R, Palettas M, Prevedello LM, Otto BA, Carrau RL Tags: J Neurosurg Source Type: research

Predicting the consistency of intracranial meningiomas using apparent diffusion coefficient maps derived from preoperative diffusion-weighted imaging.
Abstract OBJECTIVE: The consistency of meningiomas is a critical factor affecting the difficulty of resection, operative complications, and operative time. The apparent diffusion coefficient (ADC) is derived from diffusion-weighted imaging (DWI) and is calculated using two optimized b values. While the results of comparisons between the standard ADC and the consistency of meningiomas vary, the shifted ADC has been reported to be strongly correlated with liver stiffness. The purpose of the present prospective cohort study was to determine whether preoperative standard and shifted ADC maps predict the consistency of...
Source: Journal of Neurosurgery - November 13, 2020 Category: Neurosurgery Authors: Miyoshi K, Wada T, Uwano I, Sasaki M, Saura H, Fujiwara S, Takahashi F, Tsushima E, Ogasawara K Tags: J Neurosurg Source Type: research

Superselective pseudocontinuous arterial spin labeling in patients with meningioma: utility in prediction of feeding arteries and preoperative embolization feasibility.
CONCLUSIONS: In patients with meningiomas, feeding vessels are reliably predicted by ss-pCASL. This noninvasive approach, involving no iodinated contrast or radiation exposure, is particularly beneficial if there are no prospects of embolization. PMID: 33186908 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2020 Category: Neurosurgery Authors: Yoo DH, Sohn CH, Cho YD, Kang HS, Park CK, Kim JW, Kim JH Tags: J Neurosurg Source Type: research

A comparison of radial versus femoral artery access for acute stroke interventions.
CONCLUSIONS: Acute stroke intervention performed via transradial access is feasible and effective, with no significant difference in procedural and clinical outcomes compared with traditional transfemoral access. Larger studies are required to further validate the efficacy and limitations of transradial access for neurointerventional procedures. PMID: 33186909 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2020 Category: Neurosurgery Authors: Khanna O, Velagapudi L, Das S, Sweid A, Mouchtouris N, Al Saiegh F, Avery MB, Chalouhi N, Schmidt RF, Sajja K, Gooch MR, Tjoumakaris S, Rosenwasser RH, Jabbour PM Tags: J Neurosurg Source Type: research

Letter to the Editor. The Frazier Scholar Program at Penn Neurosurgery: an adaptable model for nurturing early interest in neurosurgery for current and aspiring medical students.
PMID: 33186910 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2020 Category: Neurosurgery Authors: Detchou DK, Glauser G, Dimentberg R, Maloney Wilensky E, Yoshor D, Malhotra NR Tags: J Neurosurg Source Type: research

Letter to the Editor. Validating the 5-factor modified frailty index.
PMID: 33186911 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2020 Category: Neurosurgery Authors: Poon MTC Tags: J Neurosurg Source Type: research

Letters to the Editor. Philosophical underpinnings of neurosurgical decision-making in the time of the coronavirus pandemic.
PMID: 33186912 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2020 Category: Neurosurgery Authors: Tata N, Dahdaleh NS Tags: J Neurosurg Source Type: research

Letter to the Editor. Earlier radiosurgery is related to better outcome in trigeminal neuralgia.
PMID: 33186913 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 13, 2020 Category: Neurosurgery Authors: Spina A, Boari N, Mortini P Tags: J Neurosurg Source Type: research

Endoscopic endonasal transsphenoidal direct access and Onyx embolization of a dural arteriovenous fistula mimicking a carotid-cavernous fistula: case report.
Abstract The classic presentation of a carotid-cavernous fistula (CCF) is unilateral painful proptosis, chemosis, and vision loss. Just as the goal of treatment for a dural arteriovenous fistula (dAVF) is obliteration of the entire fistulous connection and the proximal draining vein, the modern treatment of CCF is endovascular occlusion of the cavernous sinus via a transvenous or transarterial route. Here, the authors present the case of a woman with a paracavernous dAVF mimicking the clinical and radiographic presentation of a CCF. Without any endovascular route available to access the fistulous connection and ve...
Source: Journal of Neurosurgery - November 13, 2020 Category: Neurosurgery Authors: Karas PJ, North RY, Srinivasan VM, Lindquist NR, Gallagher KK, Burkhardt JK, Yoshor D, Kan P Tags: J Neurosurg Source Type: research

Cerebral venous drainage in patients with dural arteriovenous fistulas: correlation with clinical presentation.
Abstract OBJECTIVE: Dural arteriovenous fistulas (DAVFs) are abnormal, acquired arteriovenous connections within the dural leaflets. Their associated symptoms may be mild or severe and are related to the patient's venous anatomy. With the hypothesis that the patient's venous anatomy determines the development of symptoms, the authors aimed to identify which venous anatomy elements are important in the development of major symptoms in patients with a DAVF. METHODS: A multicenter study was performed based on the retrospective analysis of cerebral angiographies with systematic assessment of brain drainage pathwa...
Source: Journal of Neurosurgery - November 13, 2020 Category: Neurosurgery Authors: Melo Neto JF, Pelinca da Costa EE, Pinheiro Junior N, Batista AL, Rodesch G, Bracard S, Oliveira AG Tags: J Neurosurg Source Type: research

Editorial. Sexual harassment in neurosurgery: #UsToo.
PMID: 33171437 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 10, 2020 Category: Neurosurgery Authors: Kondziolka D, Liau LM Tags: J Neurosurg Source Type: research

Toward an understanding of sexual harassment in neurosurgery.
CONCLUSIONS: This study demonstrates that neurosurgeons report significant sexual harassment across all ages and practice settings. Sexual harassment impacts both men and women, with more than half personally subjected to this behavior and two-thirds having witnessed it. Male dominance, a hierarchical environment, and a permissive environment remain prevalent within the neurosurgical community. This is not just a historical problem, but it continues today. A change of culture will be required for neurosurgery to shed this mantle, which must include zero tolerance of this behavior, new policies, awareness of unconscious bia...
Source: Journal of Neurosurgery - November 10, 2020 Category: Neurosurgery Authors: Benzil DL, Muraszko KM, Soni P, Air EL, Orrico KO, Rutka JT Tags: J Neurosurg Source Type: research

Editorial. The quintessential nerve injury model.
PMID: 33157528 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 6, 2020 Category: Neurosurgery Authors: Umansky D, Midha R Tags: J Neurosurg Source Type: research

Readmission following extracranial-intracranial bypass surgery in the United States: nationwide rates, causes, risk factors, and volume-driven outcomes.
CONCLUSIONS: Readmission rates for patients after EC-IC bypass are comparable with those after other common cranial procedures and are primarily driven by preexisting comorbidities, socioeconomic status, and treatment at low-volume centers. Periprocedural complications, including stroke, graft failure, and wound complications, occurred at the expected rates, consistent with those in prior clinical series. The centralization of care may significantly reduce perioperative complications, readmissions, and hospital resource utilization. PMID: 33157529 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 6, 2020 Category: Neurosurgery Authors: Rumalla K, Srinivasan VM, Gaddis M, Kan P, Lawton MT, Burkhardt JK Tags: J Neurosurg Source Type: research

Femoral nerve decompression and sartorius-to-quadriceps nerve transfers for partial femoral nerve injury: a cadaveric study and early case series.
CONCLUSIONS: Femoral nerve decompression and nerve transfer using sartorius branches are a viable tool for restoring function in partial femoral nerve injuries. Sartorius branches serve as ideal donors in quadriceps nerve transfers because they are expendable, are close to their recipients, and have an adequate supply of nerve fibers. PMID: 33157531 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 6, 2020 Category: Neurosurgery Authors: McInnes CW, Ha AY, Power HA, Tung TH, Moore AM Tags: J Neurosurg Source Type: research

Incidence and characteristics of cerebral hypoxia after craniectomy in brain-injured patients: a cohort study.
CONCLUSIONS: Cerebral hypoxia is common after craniectomy, despite ICP being controlled. ET secretion and patient mobilization are common causes that are easily treatable and often not identified by standard monitoring. These results suggest that monitoring should be pursued even if ICP is controlled. The authors' findings might provide a hypothesis to explain the poor functional outcome in the recent randomized controlled trials on craniectomy after traumatic brain injury where in which brain tissue oxygen pressure was not measured. PMID: 33157533 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 6, 2020 Category: Neurosurgery Authors: Gagnon A, Laroche M, Williamson D, Giroux M, Giguère JF, Bernard F Tags: J Neurosurg Source Type: research

Rapid-stretch injury to peripheral nerves: comparison of injury models.
Abstract OBJECTIVE: Traditional animal models of nerve injury use controlled crush or transection injuries to investigate nerve regeneration; however, a more common and challenging clinical problem involves closed traction nerve injuries. The authors have produced a precise traction injury model and sought to examine how the pathophysiology of stretch injuries compares with that of crush and transection injuries. METHODS: Ninety-five late-adolescent (8-week-old) male mice underwent 1 of 7 injury grades or a sham injury (n> 10 per group): elastic stretch, inelastic stretch, stretch rupture, crush, primary c...
Source: Journal of Neurosurgery - November 6, 2020 Category: Neurosurgery Authors: Yeoh S, Warner WS, Eli I, Mahan MA Tags: J Neurosurg Source Type: research

Letter to the Editor. How to reduce unsolicited patient complaints to neurosurgeons.
PMID: 33157536 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - November 6, 2020 Category: Neurosurgery Authors: Ogiwara T, Horiuchi T Tags: J Neurosurg Source Type: research

Ballistic lobar trajectory outcomes in civilian firearm penetrating brain injury.
Abstract OBJECTIVE: Penetrating brain injury (PBI) is the most lethal of all firearm injuries, with reported survival rates of less than 20%. The projectile trajectory (PT) has been shown to impact mortality, but the significant lobar tracks have not been defined. The aim of this retrospective case-control study was to test for associations between distinct ballistic trajectories, missile types, and patient outcomes. METHODS: A total of 243 patients who presented with a PBI to the Saint Louis University emergency department from 2008 through 2019 were identified from the hospital registry. Conventional CT sca...
Source: Journal of Neurosurgery - November 6, 2020 Category: Neurosurgery Authors: Alexopoulos G, Quadri N, Khan M, Bazai H, Formoso Pico C, Fraser C, Kulkarni N, Kemp J, Coppens J, Bucholz R, Mercier P Tags: J Neurosurg Source Type: research