Critical role of platelet-derived growth factor- α in angiogenesis after indirect bypass in a murine moyamoya disease model.
CONCLUSIONS: This is the first study that denotes the role of a specific growth factor in angiogenesis after EMS for moyamoya disease by inactivating its gene in mice. The findings strongly suggest that PDGFRα signal may play an important role in developing spontaneous angiogenesis between the temporal muscle and neocortex after EMS in moyamoya disease. PMID: 32442967 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 22, 2020 Category: Neurosurgery Authors: Hayashi T, Yamamoto S, Hamashima T, Mori H, Sasahara M, Kuroda S Tags: J Neurosurg Source Type: research

Effects of implantation of a deep brain stimulation device on patient weight in Parkinson's disease and essential tremor.
Abstract OBJECTIVE: Deep brain stimulation (DBS) is a well-established therapy for treating neurological movement disorders. Some patients who have received DBS therapy have noticed significant weight gain. Further investigation into correlations between patient characteristics and weight gain following DBS device implantation, which the authors here have done, will provide physicians with useful clinical information. METHODS: The authors performed a retrospective study of patients with Parkinson's disease (PD) and essential tremor (ET) who had received DBS therapy in the period from 2012 to 2017. Patient wei...
Source: Journal of Neurosurgery - May 22, 2020 Category: Neurosurgery Authors: Monteferrante NR, Wilhelmi BG, Lambert M, Ponce FA Tags: J Neurosurg Source Type: research

Efficacy of intraarterial superselective indocyanine green videoangiography in cerebral arteriovenous malformation surgery in a hybrid operating room.
CONCLUSIONS: The results showed that intraarterial ICG videoangiography was more useful than intravenous ICG videoangiography in cerebral AVM surgery. This was especially effective in the identification of the feeder, nidus, and drainer and in the assessment of the flow dynamics of the nidus. Use of Flow 800 made it simpler and easier to evaluate these findings. PMID: 32442970 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 22, 2020 Category: Neurosurgery Authors: Shimada K, Yamaguchi T, Miyamoto T, Sogabe S, Korai M, Okazaki T, Kanematsu Y, Satomi J, Nagahiro S, Takagi Y Tags: J Neurosurg Source Type: research

Thick and diffuse cisternal clot independently predicts vasospasm-related morbidity and poor outcome after aneurysmal subarachnoid hemorrhage.
CONCLUSIONS: In a large, centrally adjudicated population of patients with aSAH, WFNS grade at admission and thick, diffuse SAH independently predicted vasospasm-related morbidity and poor 12-week clinical outcome. Patients with thick, diffuse cisternal SAH may be an important cohort to target in future clinical trials of treatment for vasospasm. PMID: 32442971 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 22, 2020 Category: Neurosurgery Authors: Aldrich EF, Higashida R, Hmissi A, Le EJ, Macdonald RL, Marr A, Mayer SA, Roux S, Bruder N Tags: J Neurosurg Source Type: research

Validation of a scoring system to evaluate the risk of rapid growth of intracranial meningiomas in neurofibromatosis type 2 patients.
Abstract OBJECTIVE: Intracranial meningiomas occur in about half of neurofibromatosis type 2 (NF2) patients and are very frequently multiple. Thus, estimating individual meningiomas' growth rates is of great interest to tailor therapeutic interventions. The Asan Intracranial Meningioma Scoring System (AIMSS) has recently been published to estimate the risk of tumor growth in sporadic meningiomas. The current study aimed to determine predictors of rapid meningioma growth in NF2 patients and to evaluate the AIMSS score in a specific NF2 cohort. METHODS: The authors performed a retrospective analysis of 92 NF2 p...
Source: Journal of Neurosurgery - May 22, 2020 Category: Neurosurgery Authors: Abi Jaoude S, Peyre M, Degos V, Goutagny S, Parfait B, Kalamarides M Tags: J Neurosurg Source Type: research

Comparative efficacy of autologous versus cadaveric saphenous vein grafts in cerebral revascularization surgery.
CONCLUSIONS: Cadaveric SVGs are a reasonable interposition graft option in cerebral revascularization surgery when autologous grafts are not available. PMID: 32442978 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 22, 2020 Category: Neurosurgery Authors: Stapleton CJ, Hussein AE, Behbahani M, Alaraj A, Amin-Hanjani S, Charbel FT Tags: J Neurosurg Source Type: research

Analysis of risk factors and clinical sequelae of direct electrical cortical stimulation-induced seizures and afterdischarges in patients undergoing awake mapping.
CONCLUSIONS: ISs and ADs, while commonly observed during intraoperative stimulation for brain mapping, do not negatively affect patient outcomes. PMID: 32442979 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 22, 2020 Category: Neurosurgery Authors: Abecassis ZA, Ayer AB, Templer JW, Yerneni K, Murthy NK, Tate MC Tags: J Neurosurg Source Type: research

Predictors of visual functional outcome following treatment for cavernous sinus meningioma.
CONCLUSIONS: Pretreatment visual functional assessment predicts visual outcomes in patients with CSM and can be used to identify patients at greater risk for vision loss. PMID: 32413851 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 15, 2020 Category: Neurosurgery Authors: Fatima N, Ding VY, Han SS, Chang SD, Meola A Tags: J Neurosurg Source Type: research

Thrombin-induced miRNA-24-1-5p upregulation promotes angiogenesis by targeting prolyl hydroxylase domain 1 in intracerebral hemorrhagic rats.
This study aimed to determine if miRNAs might be involved in thrombin-induced angiogenesis after ICH by targeting HIF-1α or its upstream prolyl hydroxylase domains (PHDs). METHODS: The study was divided into two parts. In part 1, rats received an injection of thrombin into the right globus pallidus. An miRNA array combined with miRNA target prediction, luciferase activity assay, and miRNA mimic/inhibitor transfection were used to identify candidate miRNAs and target genes. Part 2 included experiments 1 and 2. In experiment 1, rats were randomly divided into the sham group, ICH group, and ICH+hirudin-treated (thr...
Source: Journal of Neurosurgery - May 15, 2020 Category: Neurosurgery Authors: Cui H, Yang A, Zhou H, Wang Y, Luo J, Zhou J, Liu T, Li P, Zhou J, Hu E, He Z, Hu W, Tang T Tags: J Neurosurg Source Type: research

A matched-pair analysis of clinical outcomes after intracavitary cesium-131 brachytherapy versus stereotactic radiosurgery for resected brain metastases.
CONCLUSIONS: Postresection patients with BM treated with Cs-131 brachytherapy were more likely to achieve local control compared to SRS-treated patients. This study provides preliminary evidence of the potential of Cs-131 to reduce LR following gross-total resection of single BM, with minimal toxicity, and suggests the need for a prospective study to address this question. PMID: 32413856 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 15, 2020 Category: Neurosurgery Authors: Julie DA, Lazow SP, Vanderbilt DB, Taube S, Yondorf MZ, Sabbas A, Pannullo S, Schwartz TH, Wernicke AG Tags: J Neurosurg Source Type: research

Temporopolar amygdalohippocampectomy: seizure control and postoperative outcomes.
The objective of this study was to evaluate the efficacy and safety of a modified surgical approach for the treatment of temporal lobe epilepsy secondary to hippocampal sclerosis (HS). This modified approach, called temporopolar amygdalohippocampectomy (TP-AH), includes a transsylvian resection of the temporal pole and subsequent amygdalohippocampectomy utilizing the limen insula as an anatomical landmark. METHODS: A total of 61 patients who were diagnosed with HS and underwent TP-AH between 2013 and 2017 were enrolled. Patients performed pre- and postoperative diffusion tensor imaging and were classified according to...
Source: Journal of Neurosurgery - May 15, 2020 Category: Neurosurgery Authors: de Souza JPSAS, Ayub G, Nogueira M, Zanao T, Lopes TM, Pimentel-Silva LR, Domene V, Marquez G, Yasuda CL, Ribeiro LF, Campos BM, Vasconcellos J, Rogerio F, Joaquim AF, Cendes F, Tedeschi H, Ghizoni E Tags: J Neurosurg Source Type: research

Preoperative localization of seizure onset zones by magnetic source imaging, EEG-correlated functional MRI, and their combination.
CONCLUSIONS: Both MSI and EEG-fMRI can assist in the presurgical evaluation of patients with refractory epilepsy. The additive use of both tests confers a high identification rate in finding the SL. This combination can help in focusing implantation of icEEG electrodes targeting the SOZ. PMID: 32413858 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 15, 2020 Category: Neurosurgery Authors: Berger A, Cohen N, Fahoum F, Medvedovsky M, Meller A, Ekstein D, Benifla M, Aizenstein O, Fried I, Gazit T, Strauss I Tags: J Neurosurg Source Type: research

Invasive neuromonitoring with an extended definition of delayed cerebral ischemia is associated with improved outcome after poor-grade subarachnoid hemorrhage.
CONCLUSIONS: In this cohort analysis of poor-grade SAH patients, the introduction of INM and the extension of the classic DCI definition toward a functional dimension resulted in an earlier detection and treatment of DCI events. This led to an overall decrease in DCI-related infarctions and an improvement in outcome. PMID: 32413866 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 15, 2020 Category: Neurosurgery Authors: Veldeman M, Albanna W, Weiss M, Conzen C, Schmidt TP, Schulze-Steinen H, Wiesmann M, Clusmann H, Schubert GA Tags: J Neurosurg Source Type: research

Omega-3 fatty acid supplementation in severe brain trauma: case for a large multicenter trial.
PMID: 32413868 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 15, 2020 Category: Neurosurgery Authors: Bailes JE, Abusuwwa R, Arshad M, Chowdhry SA, Schleicher D, Hempeck N, Gandhi YN, Jaffa Z, Bokhari F, Karahalios D, Barkley J, Patel V, Sears B Tags: J Neurosurg Source Type: research

Letter to the Editor. Double-crescent sign and superficial subarachnoid CSF space expansion.
PMID: 32384265 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 8, 2020 Category: Neurosurgery Authors: Tosaka M Tags: J Neurosurg Source Type: research

Development and validation of a risk scoring model for postoperative adult moyamoya disease.
CONCLUSIONS: The authors' scoring system is readily adoptable to predict the postoperative outcome for MMD. Their data revealed the importance of smoking and hyperlipidemia, which were the only modifiable factors included in the scoring system. The authors validated their scoring system both internally and externally and maintained good performance, highlighting the system's generalizability and reliability. PMID: 32384266 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 8, 2020 Category: Neurosurgery Authors: Kim M, Park W, Chung Y, Lee SU, Park JC, Kwon DH, Ahn JS, Lee S Tags: J Neurosurg Source Type: research

Letter to the Editor. Healthy competition.
PMID: 32384267 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 8, 2020 Category: Neurosurgery Authors: Zhang JJY, Lee KS Tags: J Neurosurg Source Type: research

Global neurosurgery: a scoping review detailing the current state of international neurosurgical outreach.
CONCLUSIONS: This review provides a detailed overview of current global neurosurgery efforts, elucidates gaps in the existing literature, and identifies the LMICs that may benefit from further efforts to improve accessibility to essential neurosurgical care worldwide. PMID: 32384268 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 8, 2020 Category: Neurosurgery Authors: Fuller AT, Barkley A, Du R, Elahi C, MScGH, Tafreshi AR, Von Isenburg M, Haglund MM Tags: J Neurosurg Source Type: research

Near-complete regression 19 years after Gamma Knife radiosurgery of vestibular schwannoma with massive pseudoprogression: case report.
Abstract Gamma Knife radiosurgery (GKRS) is a frequent treatment choice for patients with small- to moderate-sized vestibular schwannoma (VS). However, pseudoprogression after GKRS is commonly observed, with a reported incidence ranging from 7% to 77%. The wide range of the reported incidence of pseudoprogression reflects the fact that there is no consensus on how it should be diagnosed.The authors present the case of a 66-year-old woman who had a 2.5-cm right-sided VS treated with GKRS in 1997. The first posttreatment MRI obtained 5 months later showed that the tumor volume had increased to 9.7 cm3. The tumor vol...
Source: Journal of Neurosurgery - May 8, 2020 Category: Neurosurgery Authors: Li LF, Yu CP, Tsang AC, Taw BB, Lui WM Tags: J Neurosurg Source Type: research

Extent of resection, molecular signature, and survival in 1p19q-codeleted gliomas.
The objectives of the present study were twofold: 1) to assess the association between EOR and survival for patients with oligodendrogliomas in the National Cancer Database (NCDB), which includes information on mutation status, and 2) to demonstrate the same effect for all patients with 1p/19q codeleted gliomas in the NCDB. METHODS: The NCDB was queried for all cases of oligodendroglioma between 2004 and 2014, with follow-up dates through 2016. The authors found 2514 cases of histologically confirmed oligodendrogliomas for the final analysis of the effect of EOR on survival. Upon further query, 1067 1p/19q-codeleted t...
Source: Journal of Neurosurgery - May 8, 2020 Category: Neurosurgery Authors: Garton ALA, Kinslow CJ, Rae AI, Mehta A, Pannullo SC, Magge RS, Ramakrishna R, McKhann GM, Sisti MB, Bruce JN, Canoll P, Cheng SK, Sonabend AM, Wang TJC Tags: J Neurosurg Source Type: research

Defining the optimal target for anterior thalamic deep brain stimulation in patients with drug-refractory epilepsy.
Abstract OBJECTIVE: The anterior thalamic nucleus (ATN) is a common target for deep brain stimulation (DBS) for the treatment of drug-refractory epilepsy. However, no atlas-based optimal DBS (active contacts) target within the ATN has been definitively identified. The object of this retrospective study was to analyze the relationship between the active contact location and seizure reduction to establish an atlas-based optimal target for ATN DBS. METHODS: From among 25 patients who had undergone ATN DBS surgery for drug-resistant epilepsy between 2016 and 2018, those who had follow-up evaluations for more than...
Source: Journal of Neurosurgery - May 8, 2020 Category: Neurosurgery Authors: Guo W, Koo BB, Kim JH, Bhadelia RA, Seo DW, Hong SB, Joo EY, Lee S, Lee JI, Cho KR, Shon YM Tags: J Neurosurg Source Type: research

Clinical dose profile of Gamma Knife stereotactic radiosurgery for extensive brain metastases.
Abstract OBJECTIVE: The use of Gamma Knife stereotactic radiosurgery (GKSRS) for the treatment of extensive intracranial metastases has been expanding due to its superior dosimetry and efficacy. However, there remains a dearth of data regarding the dose parameters in actual clinical scenarios. The authors endeavored to calculate the radiation dose to the brain when treating ≥ 15 brain metastases with GKSRS. METHODS: This retrospective analysis reviewed dosage characteristics for patients requiring single-session GKSRS for the treatment of ≥ 15 brain metastases. Forty-two patients met the inclusion crite...
Source: Journal of Neurosurgery - May 8, 2020 Category: Neurosurgery Authors: Bowden GN, Kim JO, Faramand A, Fallon K, Flickinger J, Lunsford LD Tags: J Neurosurg Source Type: research

A simple and cost-effective model for ventricular catheter placement training: technical note.
CONCLUSIONS: The presented brain model is easy to replicate, inexpensive, anatomically accurate, and provides a medium for neurosurgeons to teach and practice ventricular catheter placement in a risk-free environment. PMID: 32357317 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 1, 2020 Category: Neurosurgery Authors: Todnem N, Nguyen KD, Reddy V, Grogan D, Waitt T, Alleyne CH Tags: J Neurosurg Source Type: research

What factors impact the clinical outcome of magnetic resonance imaging-guided focused ultrasound thalamotomy for essential tremor?
CONCLUSIONS: Younger age and lower baseline CRST score were favorable outcome factors. It is important to assess predictive factors when applying MRgFUS. PMID: 32357330 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 1, 2020 Category: Neurosurgery Authors: Fukutome K, Kuga Y, Ohnishi H, Hirabayashi H, Nakase H Tags: J Neurosurg Source Type: research

External validation of current prediction systems of improvement after decompression surgery in Chiari malformation type I patients: can we do better?
CONCLUSIONS: Previously published algorithms failed to provide prediction value with regard to clinically meaningful improvement following suboccipital decompression in adult CM-I patients. Future models and practical scoring systems are still required to improve the decision-making process. PMID: 32357331 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 1, 2020 Category: Neurosurgery Authors: Feghali J, Xie Y, Chen Y, Li S, Huang J Tags: J Neurosurg Source Type: research

Letter to the Editor. Radiosurgery is a valuable alternative to microvascular decompression for glossopharyngeal neuralgia.
PMID: 32357332 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 1, 2020 Category: Neurosurgery Authors: Peciu-Florianu I, Vermandel M, Reyns N, Tuleasca C Tags: J Neurosurg Source Type: research

Predictors of 30-day hospital readmission after mechanical thrombectomy for acute ischemic stroke.
CONCLUSIONS: The study data demonstrate that hypertension, length of hospital stay, and hemorrhagic conversion were predictors of 30-day hospital readmission in stroke patients after mechanical thrombectomy. Infection was the most common cause of 30-day readmission, followed by cardiac and cerebrovascular diagnoses. These results therefore may serve to identify patients within the stroke population who require increased surveillance following discharge to reduce complications and unplanned readmissions. PMID: 32357335 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 1, 2020 Category: Neurosurgery Authors: Mouchtouris N, Al Saiegh F, Valcarcel B, Andrews CE, Fitchett E, Nauheim D, Moskal D, Herial N, Jabbour P, Tjoumakaris SI, Sharan AD, Rosenwasser RH, Gooch MR Tags: J Neurosurg Source Type: research

Levels of caspase-1 in cerebrospinal fluid of patients with traumatic brain injury: correlation with intracranial pressure and outcome.
CONCLUSIONS: In this cohort of patients with TBI who were admitted to the neurosurgical ICU, the inflammasome protein caspase-1 is increased in the CSF of patients with high ICP, especially on days 2 and 3 after TBI. Also the protein levels of caspase-1 in CSF were higher in patients with poor outcome during the first 96 hours after TBI. Moreover, not only the absolute value of caspase-1 in CSF but also its trend is associated with poor outcomes. PMID: 32357337 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 1, 2020 Category: Neurosurgery Authors: Pérez-Bárcena J, Crespí C, Frontera G, Llompart-Pou JA, Salazar O, Goliney V, Ibáñez J, Bullock MR, de Rivero Vaccari JP Tags: J Neurosurg Source Type: research

Altered corticospinal microstructure and motor cortex excitability in gliomas: an advanced tractography and transcranial magnetic stimulation study.
CONCLUSIONS: SD tractography can demonstrate microstructural abnormality within the CST of patients with IDH1-mutant gliomas that correlates to the functional abnormality measured with nTMS. PMID: 32357341 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 1, 2020 Category: Neurosurgery Authors: Mirchandani AS, Beyh A, Lavrador JP, Howells H, Dell'Acqua F, Vergani F Tags: J Neurosurg Source Type: research

Correlation between localization of supratentorial glioma to the precentral gyrus and difficulty in identification of the motor area during awake craniotomy.
CONCLUSIONS: Identification of the motor area can be difficult when a supratentorial glioma is localized to the precentral gyrus. The authors' findings are important when performing awake craniotomy for glioma located within or close to the motor area or the pyramidal tract. A combination of transcortical motor evoked potential monitoring and awake craniotomy including subcortical motor mapping may be needed for removal of gliomas showing negative responses in the motor area to preserve the motor-related subcortical fibers. PMID: 32357342 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - May 1, 2020 Category: Neurosurgery Authors: Saito T, Muragaki Y, Tamura M, Maruyama T, Nitta M, Tsuzuki S, Fukui A, Kawamata T Tags: J Neurosurg Source Type: research

An altered posterior question-mark incision is associated with a reduced infection rate of cranioplasty after decompressive hemicraniectomy.
n H Abstract OBJECTIVE: Performing a cranioplasty (CP) after decompressive craniotomy is a straightforward neurosurgical procedure, but it remains associated with a high complication rate. Surgical site infection (SSI), aseptic bone resorption (aBR), and need for a secondary CP are the most common complications. This observational study aimed to identify modifiable risk factors to prevent CP failure. METHODS: A retrospective analysis was performed of all patients who underwent CP following decompressive hemicraniectomy (DHC) between 2010 and 2018 at a single institution. Predictors of SSI, aBR, and need for a...
Source: Journal of Neurosurgery - April 24, 2020 Category: Neurosurgery Authors: Veldeman M, Daleiden L, Hamou H, Höllig A, Clusmann H Tags: J Neurosurg Source Type: research

How safe are elective craniotomies in elderly patients in neurosurgery today? A prospective cohort study of 1452 consecutive cases.
Raabe A Abstract OBJECTIVE: With global aging, elective craniotomies are increasingly being performed in elderly patients. There is a paucity of prospective studies evaluating the impact of these procedures on the geriatric population. The goal of this study was to assess the safety of elective craniotomies for elderly patients in modern neurosurgery. METHODS: For this cohort study, adult patients, who underwent elective craniotomies between November 1, 2011, and October 31, 2018, were allocated to 3 age groups (group 1,
Source: Journal of Neurosurgery - April 24, 2020 Category: Neurosurgery Authors: Schär RT, Tashi S, Branca M, Söll N, Cipriani D, Schwarz C, Pollo C, Schucht P, Ulrich CT, Beck J, Z'Graggen WJ, Raabe A Tags: J Neurosurg Source Type: research

Clip retraction of the tentorium: application of a novel technique for tentorial retraction during supracerebellar transtentorial approaches.
Abstract Supracerebellar transtentorial (SCTT) approaches have become a popular option for treatment of a variety of pathologies in the medial and basal temporal and occipital lobes and thalamus. Transtentorial approaches provide numerous advantages over transcortical approaches, including obviating the need to traverse eloquent cortex, not requiring parenchymal retraction, and circumventing critical vascular structures. All of these approaches require a tentorial opening, and numerous techniques for retraction of the incised tentorium have been described, including sutures, fixed retractors, and electrocautery. H...
Source: Journal of Neurosurgery - April 24, 2020 Category: Neurosurgery Authors: Baranoski JF, Bajaj A, Przybylowski CJ, Catapano JS, Frisoli FA, Lang MJ, Lawton MT Tags: J Neurosurg Source Type: research

Predicting final lesion characteristics during MR-guided focused ultrasound pallidotomy for treatment of Parkinson's disease.
CONCLUSIONS: The authors' acoustic simulations accurately depicted the characteristics of thermal lesions encountered following MRgFUS pallidotomy. MR thermometry data can predict postprocedure day 1 GPi lesion characteristics using a 48°C threshold model. Finally, the lower treatment efficiency of pallidotomy may make GPi lesioning challenging in patients with a low SDR. PMID: 32330882 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 24, 2020 Category: Neurosurgery Authors: Miller TR, Guo S, Melhem ER, Eisenberg HM, Zhuo J, Kelm N, Dayan M, Gullapalli RP, Gandhi D Tags: J Neurosurg Source Type: research

Relationship between direct cortical stimulation and induced high-frequency activity for language mapping during SEEG recording.
CONCLUSIONS: DCS language mapping appears to be more appropriate for an extensive temporal mapping than induced HFA mapping. Furthermore, induced HFA should be used as a complement to DCS to preselect the number of stimulated sites during DCS, by omitting those reported as HFA-. This may be a considerable advantage because it allows a reduction in the duration of the stimulation procedure. Several parameters to be used for each method are discussed and the results are interpreted in relation to previous results reported in ECOG studies. PMID: 32330883 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 24, 2020 Category: Neurosurgery Authors: Cuisenier P, Testud B, Minotti L, El Bouzaïdi Tiali S, Martineau L, Job AS, Trébuchon A, Deman P, Bhattacharjee M, Hoffmann D, Lachaux JP, Baciu M, Kahane P, Perrone-Bertolotti M Tags: J Neurosurg Source Type: research

Neuromodulation of the lingual nerve: a novel technique.
Abstract Acute injury of the trigeminal nerve or its branches can result in posttraumatic trigeminal neuropathy (PTTN). Affected patients suffer from chronic debilitating symptoms long after they have recovered from the inciting trauma. Symptoms vary but usually consist of paresthesia, allodynia, dysesthesia, hyperalgesia, or a combination of these symptoms. PTTN of the trigeminal nerve can result from a variety of traumas, including iatrogenic injury from various dental and maxillofacial procedures. Treatments include medications, pulsed radiofrequency modulation, and microsurgical repair. Although trigeminal ner...
Source: Journal of Neurosurgery - April 24, 2020 Category: Neurosurgery Authors: Talbot CE, Zhao K, Ward M, Kandinov A, Mammis A, Paskhover B Tags: J Neurosurg Source Type: research

Dissecting the default mode network: direct structural evidence on the morphology and axonal connectivity of the fifth component of the cingulum bundle.
CONCLUSIONS: Through the fiber microdissection technique, the authors were able to provide original, direct structural evidence on the existence, morphology, axonal connectivity, and correlative anatomy of what proved to be a discrete white matter pathway, previously described as the CB-V, connecting the precuneus and medial temporal lobe. PMID: 32330886 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 24, 2020 Category: Neurosurgery Authors: Skandalakis GP, Komaitis S, Kalyvas A, Lani E, Kontrafouri C, Drosos E, Liakos F, Piagkou M, Placantonakis DG, Golfinos JG, Fountas KN, Kapsalaki EZ, Hadjipanayis CG, Stranjalis G, Koutsarnakis C Tags: J Neurosurg Source Type: research

Results of a third Gamma Knife radiosurgery for trigeminal neuralgia.
CONCLUSIONS: A third GKRS is an effective treatment option for TN patients who have pain relapse after repeat GKRS. Pain outcomes of a third GKRS are similar to those following a first or second GKRS. Toxicity is tolerable in patients with a distally placed shot at the third GKRS. PMID: 32330887 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 24, 2020 Category: Neurosurgery Authors: Helis CA, Hughes RT, Munley MT, Bourland JD, Jacobson T, Lucas JT, Cramer CK, Tatter SB, Laxton AW, Chan MD Tags: J Neurosurg Source Type: research

Letter to the Editor. Pupillometry and neurotrauma: point-of-care technologies versus point-of-care techniques.
PMID: 32330889 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 24, 2020 Category: Neurosurgery Authors: Pavlov O, Martinez-Perez R, Agrawal A, Garcia-Ballestas E, Moscote-Salazar LR Tags: J Neurosurg Source Type: research

Letter to the Editor. Cognitive performance of patients with low-grade glioma.
PMID: 32330890 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 24, 2020 Category: Neurosurgery Authors: de Vries F Tags: J Neurosurg Source Type: research

Editorial. Lessons learned: special precautions for performing emergency cerebrovascular procedures amid the COVID-19 pandemic.
PMID: 32330897 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 24, 2020 Category: Neurosurgery Authors: Tong X, Yang Y Tags: J Neurosurg Source Type: research

Editorial. Community practice in the time of COVID-19.
PMID: 32330898 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 24, 2020 Category: Neurosurgery Authors: Prall JA, Davis JD, Jenkins NR Tags: J Neurosurg Source Type: research

Editorial. Impact of COVID-19 on neurosurgery resident research training.
PMID: 32330899 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 24, 2020 Category: Neurosurgery Authors: Clark VE Tags: J Neurosurg Source Type: research

Editorial. COVID-19 and neurosurgical practice: an interim report.
PMID: 32330900 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 24, 2020 Category: Neurosurgery Authors: Amin-Hanjani S, Bambakidis NC, Barker FG, Carter BS, Cockroft KM, Du R, Fraser JF, Hamilton MG, Huang J, Jane JA, Jensen RL, Kaplitt MG, Kaufmann AM, Pilitsis JG, Riina HA, Schulder M, Vogelbaum MA, Yang LJS, Zada G Tags: J Neurosurg Source Type: research

Stereotactic radiofrequency thermocoagulation and resective surgery for patients with hypothalamic hamartoma.
CONCLUSIONS: For patients with small HHs, SRT provides similar seizure outcomes to RS with a less invasive procedure. Patients who underwent SRT experienced fewer and lighter adverse effects than patients who had RS. Patients with giant HHs were more likely to undergo multiple HH resections. PMID: 32302977 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 17, 2020 Category: Neurosurgery Authors: Wang S, Zhao M, Li T, Zhang C, Zhou J, Wang M, Wang X, Liu Z, Ma K, Luan G, Guan Y Tags: J Neurosurg Source Type: research

Echolucent carotid plaque is associated with restenosis after carotid endarterectomy.
CONCLUSIONS: Predominantly echolucent carotid plaques, as measured by GSM, had a higher restenosis risk at 1 year than echogenic plaques. PMID: 32302982 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 17, 2020 Category: Neurosurgery Authors: Li Q, Liu B, Zhao Y, Liu Y, Gao M, Jia L, Jiao L, Hua Y Tags: J Neurosurg Source Type: research

Expression of additional transcription factors is of prognostic value for aggressive behavior of pituitary adenomas.
CONCLUSIONS: These data suggest a more aggressive behavior of TFGA-positive adenomas if an additional TF is expressed within the tumor cells. Shorter radiographic surveillance and earlier consideration for retreatment should be recommended in these adenoma types. PMID: 32302984 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 17, 2020 Category: Neurosurgery Authors: Micko A, Rötzer T, Hoftberger R, Vila G, Oberndorfer J, Frischer JM, Knosp E, Wolfsberger S Tags: J Neurosurg Source Type: research

Delayed hospital admission of patients with aneurysmal subarachnoid hemorrhage: clinical presentation, treatment strategies, and outcome.
Abstract OBJECTIVE: Timely aneurysm occlusion and neurointensive care treatment are key principles in the management of aneurysmal subarachnoid hemorrhage (aSAH) to prevent secondary brain injury. Patients with early (EHA) and delayed hospital admission (DHA) were compared in terms of clinical presentation, treatment strategies, aSAH-related complications, and outcome. METHODS: In this retrospective study, consecutive aSAH patients were treated at a single neurovascular center between 2009 and 2019. Propensity score matching was performed to account for divergent baseline characteristics. RESULTS: Among ...
Source: Journal of Neurosurgery - April 17, 2020 Category: Neurosurgery Authors: Goertz L, Pflaeging M, Hamisch C, Kabbasch C, Pennig L, von Spreckelsen N, Laukamp K, Timmer M, Goldbrunner R, Brinker G, Krischek B Tags: J Neurosurg Source Type: research

Predictors of an academic career among fellowship-trained open vascular and endovascular neurosurgeons.
CONCLUSIONS: The authors report that an h-index of ≥ 2 during residency predicts pursuit of an academic career among vascular and endovascular neurosurgeons. Additionally, attendance of a residency program affiliated with a top research medical school independently predicts an academic career trajectory among endovascular neurosurgeons. This result may be useful to identify and mentor residents interested in academic vascular neurosurgery. PMID: 32302986 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 17, 2020 Category: Neurosurgery Authors: Khalafallah AM, Jimenez AE, Caplan JM, McDougall CG, Huang J, Mukherjee D, Tamargo RJ Tags: J Neurosurg Source Type: research

Editorial. Impact of COVID-19 on neurosurgery resident training and education.
PMID: 32302990 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 17, 2020 Category: Neurosurgery Authors: Bambakidis NC, Tomei KL Tags: J Neurosurg Source Type: research