Periprocedural intravenous heparin in patients with acute ischemic stroke treated with endovascular thrombectomy after intravenous thrombolysis
CONCLUSIONS: The results showed that periprocedural heparin is associated with an increased risk of unfavorable outcomes and SICH in patients treated with EVT after IVT. Further studies are warranted to evaluate the utility and safety of periprocedural heparin.PMID:38552231 | DOI:10.3171/2024.1.JNS232584 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Hao Wang Kang Yuan Xianjun Huang Yi Zhong Mengdi Xie Ruidong Ye Yunfei Han Qiushi Lv Qingshi Zhao Rui Liu Source Type: research
Epidemiology of moderate traumatic brain injury and factors associated with poor neurological outcome
CONCLUSIONS: Almost half of the patients with moderate TBI had poor neurological outcome at hospital discharge. Several factors including older age, higher CCI, GCS scores of 9 or 10, severe trauma, and mechanical ventilation or craniotomy were found to be associated with poor neurological outcome in patients with moderate TBI. Additionally, these data suggest that tranexamic acid administration and admission to the ICU might be important for improving prognosis. Further investigations are warranted to elucidate the appropriate management for patients with moderate TBI.PMID:38552232 | DOI:10.3171/2024.1.JNS232627 (Source: ...
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Shu Utsumi Shingo Ohki Nobuaki Shime Source Type: research
Are hemodynamics responsible for inflammatory changes in venous vessel walls? A quantitative study of wall-enhancing intracranial arteriovenous malformation draining veins
CONCLUSIONS: This novel multimodal investigation of hemodynamics in AVM draining veins allows for precise prediction of occurring shear- and flow-related phenomena in enhanced vessel walls. These findings may suggest low shear to be a local predisposing factor for venous stenosis in AVMs.PMID:38552234 | DOI:10.3171/2024.1.JNS232625 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Janneck Stahl Laura Stone McGuire Mark Rizko Sylvia Saalfeld Philipp Berg Ali Alaraj Source Type: research
Association of frequent NF2 mutations with spinal location predominance and worse outcomes in psammomatous meningiomas
CONCLUSIONS: Female sex and spinal location predominance were statistically significant in PMs. NF2 mutation was an independent predictor for worse PFS of PMs. Of note, NF2 mutation was detected in all SPMs but in only 38.46% of CPMs, revealing a significant difference.PMID:38552238 | DOI:10.3171/2024.1.JNS232450 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Leihao Ren Qing Xie Jiaojiao Deng Jiawei Chen Jinxiu Yu Daijun Wang Hiroaki Wakimoto Ye Gong Lingyang Hua Source Type: research
Molecularly targeted protease-activated probes for visualization of glioblastoma: a comparison with 5-ALA
CONCLUSIONS: The cysteine cathepsin-cleavable probe 6QC-ICG is activated by glioma cells and tumor-associated macrophages, leading to a high contrast between tumor and nontumorous brain tissue that is superior to that of the current standard, 5-ALA. In addition to a well-defined mechanism of action, protease-activated probes that use NIR fluorophores (e.g., indocyanine green) have the advantage of low absorption and scattering of the NIR light and lower tissue autofluorescence. These results suggest that 6QC-ICG has the potential to become the targeted agent in intraoperative detection of GBM tissue using fluorescence imag...
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Dora Kone čná Petr V ýmola Nikola Ternerov á Barbora V ýmolová Elena Garcia-Borja Rosana Mateu Filip Šroubek Jan Pankr ác John C Widen Matthew Bogyo David Netuka Petr Bu šek Aleksi Šedo Source Type: research
Deep learning-based quantification of total bleeding volume and its association with complications, disability, and death in patients with aneurysmal subarachnoid hemorrhage
CONCLUSIONS: Elevated TBV is associated with a greater risk of hydrocephalus, rebleeding, death, and poor prognosis.PMID:38552240 | DOI:10.3171/2024.1.JNS232280 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Ping Hu Yanze Wu Tengfeng Yan Lei Shu Feng Liu Bing Xiao Minhua Ye Miaojing Wu Shigang Lv Xingen Zhu Source Type: research
Benefits of stereotactic radiosurgical anterior capsulotomy for obsessive-compulsive disorder: a meta-analysis
CONCLUSIONS: Stereotactic radiosurgical AC is an effective technique for treating OCD. Its efficacy is similar to that of AC performed via other lesioning techniques.PMID:38552242 | DOI:10.3171/2024.1.JNS231537 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Rishabh Gupta Jeffrey W Chen Natasha C Hughes Mohammad Hamo Samuel Jean-Baptiste Danika L Paulo Hani Chanbour Run Fan Fei Ye Abhiram Vadali Anthony Cmelak Sarah K Bick Source Type: research
Erratum. Grade 3 meningioma survival and recurrence outcomes in an international multicenter cohort
J Neurosurg. 2024 Mar 29:1. doi: 10.3171/2024.2.JNS23465a. Online ahead of print.NO ABSTRACTPMID:38552244 | DOI:10.3171/2024.2.JNS23465a (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Serge Makarenko Source Type: research
Periprocedural intravenous heparin in patients with acute ischemic stroke treated with endovascular thrombectomy after intravenous thrombolysis
CONCLUSIONS: The results showed that periprocedural heparin is associated with an increased risk of unfavorable outcomes and SICH in patients treated with EVT after IVT. Further studies are warranted to evaluate the utility and safety of periprocedural heparin.PMID:38552231 | DOI:10.3171/2024.1.JNS232584 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Hao Wang Kang Yuan Xianjun Huang Yi Zhong Mengdi Xie Ruidong Ye Yunfei Han Qiushi Lv Qingshi Zhao Rui Liu Source Type: research
Epidemiology of moderate traumatic brain injury and factors associated with poor neurological outcome
CONCLUSIONS: Almost half of the patients with moderate TBI had poor neurological outcome at hospital discharge. Several factors including older age, higher CCI, GCS scores of 9 or 10, severe trauma, and mechanical ventilation or craniotomy were found to be associated with poor neurological outcome in patients with moderate TBI. Additionally, these data suggest that tranexamic acid administration and admission to the ICU might be important for improving prognosis. Further investigations are warranted to elucidate the appropriate management for patients with moderate TBI.PMID:38552232 | DOI:10.3171/2024.1.JNS232627 (Source: ...
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Shu Utsumi Shingo Ohki Nobuaki Shime Source Type: research
Are hemodynamics responsible for inflammatory changes in venous vessel walls? A quantitative study of wall-enhancing intracranial arteriovenous malformation draining veins
CONCLUSIONS: This novel multimodal investigation of hemodynamics in AVM draining veins allows for precise prediction of occurring shear- and flow-related phenomena in enhanced vessel walls. These findings may suggest low shear to be a local predisposing factor for venous stenosis in AVMs.PMID:38552234 | DOI:10.3171/2024.1.JNS232625 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Janneck Stahl Laura Stone McGuire Mark Rizko Sylvia Saalfeld Philipp Berg Ali Alaraj Source Type: research
Association of frequent NF2 mutations with spinal location predominance and worse outcomes in psammomatous meningiomas
CONCLUSIONS: Female sex and spinal location predominance were statistically significant in PMs. NF2 mutation was an independent predictor for worse PFS of PMs. Of note, NF2 mutation was detected in all SPMs but in only 38.46% of CPMs, revealing a significant difference.PMID:38552238 | DOI:10.3171/2024.1.JNS232450 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Leihao Ren Qing Xie Jiaojiao Deng Jiawei Chen Jinxiu Yu Daijun Wang Hiroaki Wakimoto Ye Gong Lingyang Hua Source Type: research
Molecularly targeted protease-activated probes for visualization of glioblastoma: a comparison with 5-ALA
CONCLUSIONS: The cysteine cathepsin-cleavable probe 6QC-ICG is activated by glioma cells and tumor-associated macrophages, leading to a high contrast between tumor and nontumorous brain tissue that is superior to that of the current standard, 5-ALA. In addition to a well-defined mechanism of action, protease-activated probes that use NIR fluorophores (e.g., indocyanine green) have the advantage of low absorption and scattering of the NIR light and lower tissue autofluorescence. These results suggest that 6QC-ICG has the potential to become the targeted agent in intraoperative detection of GBM tissue using fluorescence imag...
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Dora Kone čná Petr V ýmola Nikola Ternerov á Barbora V ýmolová Elena Garcia-Borja Rosana Mateu Filip Šroubek Jan Pankr ác John C Widen Matthew Bogyo David Netuka Petr Bu šek Aleksi Šedo Source Type: research
Deep learning-based quantification of total bleeding volume and its association with complications, disability, and death in patients with aneurysmal subarachnoid hemorrhage
CONCLUSIONS: Elevated TBV is associated with a greater risk of hydrocephalus, rebleeding, death, and poor prognosis.PMID:38552240 | DOI:10.3171/2024.1.JNS232280 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Ping Hu Yanze Wu Tengfeng Yan Lei Shu Feng Liu Bing Xiao Minhua Ye Miaojing Wu Shigang Lv Xingen Zhu Source Type: research
Benefits of stereotactic radiosurgical anterior capsulotomy for obsessive-compulsive disorder: a meta-analysis
CONCLUSIONS: Stereotactic radiosurgical AC is an effective technique for treating OCD. Its efficacy is similar to that of AC performed via other lesioning techniques.PMID:38552242 | DOI:10.3171/2024.1.JNS231537 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Rishabh Gupta Jeffrey W Chen Natasha C Hughes Mohammad Hamo Samuel Jean-Baptiste Danika L Paulo Hani Chanbour Run Fan Fei Ye Abhiram Vadali Anthony Cmelak Sarah K Bick Source Type: research
