Minimally invasive keyhole approach for supramaximal frontal glioma resections: technical note
CONCLUSIONS: Keyhole approaches enabled successful SMR of frontal gliomas without added risks. Robust anatomical knowledge and meticulous surgical technique are paramount for obtaining successful resections.PMID:38564815 | DOI:10.3171/2023.7.JNS231363 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 2, 2024 Category: Neurosurgery Authors: Mart ín A Merenzon Mynor J Mendez Valdez Jay Chandar Victor M Lu Francisco Marco Del Pont Alexis A Morell Daniel G Eichberg Lekhaj Daggubati Carolina G Benjamin Ashish H Shah Michael E Ivan Ricardo J Komotar Source Type: research
neuroGPT-X: toward a clinic-ready large language model
CONCLUSIONS: The present study, with its subspecialist-level performance in generating written responses to complex neurosurgical problems for which evidence-based consensus for management is lacking, suggests that context-enriched LLMs show promise as a point-of-care medical resource. The authors anticipate that this work will be a springboard for expansion into more medical specialties, incorporating evidence-based clinical information and developing expert-level dialogue surrounding LLMs in healthcare.PMID:38564804 | DOI:10.3171/2023.7.JNS23573 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 2, 2024 Category: Neurosurgery Authors: Edward Guo Mehul Gupta Sarthak Sinha Karl R össler Marcos Tatagiba Ryojo Akagami Ossama Al-Mefty Taku Sugiyama Philip E Stieg Gwynedd E Pickett Madeleine de Lotbiniere-Bassett Rahul Singh Sanju Lama Garnette R Sutherland Source Type: research
Association of persistent postoperative hyperglycemia with mortality after elective craniotomy
CONCLUSIONS: In patients undergoing an elective craniotomy, moderate and severe persistent postoperative hyperglycemia were associated with an increased risk of mortality compared with normoglycemia, regardless of preoperative hyperglycemia.PMID:38564805 | DOI:10.3171/2023.7.JNS23777 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 2, 2024 Category: Neurosurgery Authors: Jialing He Yu Zhang Lu Jia Xin Cheng Yixin Tian Pengfei Hao Tiangui Li Yangchun Xiao Liyuan Peng Yuning Feng Haidong Deng Peng Wang Weelic Chong Yang Hai Lvlin Chen Chao You Fang Fang Source Type: research
Risk Analysis Index as a preoperative frailty tool for elective ventriculoperitoneal shunt surgery for idiopathic normal pressure hydrocephalus
CONCLUSIONS: In a nationwide database analysis, increasing frailty, as measured by RAI, was associated with NHD, 30-day mortality, unplanned readmission, eLOS, and postoperative complications. Although the RAI outperformed the mFI-5, it is essential to account for the potentially reversible clinical issues related to the underlying disease process, as these factors may inflate frailty scores, assign undue risk, and diminish their utility. This knowledge may enhance provider understanding of the impact of frailty on postoperative outcomes for patients with iNPH, while highlighting the potential constraints associated with f...
Source: Journal of Neurosurgery - April 2, 2024 Category: Neurosurgery Authors: Evan Courville Kavelin Rumalla Syed Faraz Kazim Alis J Dicpinigaitis Meic Schmidt Timothy M Robinson Christian A Bowers Source Type: research
Sanford Larson, MD, PhD: a pioneering neurosurgeon, scientist, and educator
J Neurosurg. 2023 Oct 6;140(4):1177-1182. doi: 10.3171/2023.7.JNS23256. Print 2024 Apr 1.ABSTRACTDr. Sanford Larson, MD, PhD (1929-2012), was an influential figure in spinal neurosurgery. Dr. Larson played a pivotal role in establishing neurosurgery's foothold in spinal surgery by serving as the inaugural chair of the Joint Section on Disorders of the Spine and Peripheral Nerves and as a president of the Cervical Spine Research Society. He made many advances in spine care, most notably the modification and popularization of the lateral extracavitary approach to the thoracolumbar spine. Dr. Larson established the neurosurge...
Source: Journal of Neurosurgery - April 2, 2024 Category: Neurosurgery Authors: Andrew L Waack Jason L Schroeder Alastair T Hoyt Source Type: research
Quantitative noninvasive measurement of cerebrospinal fluid flow in shunted hydrocephalus
CONCLUSIONS: The PC-MRI sequence provided accurate and reliable clinical measurements of CSF flow in shunt-treated patients. This work provides the necessary framework to include PC-MRI as an immediate addition to the clinical setting in the noninvasive evaluation of shunt function and in future clinical investigations of CSF physiology.PMID:38564811 | DOI:10.3171/2023.7.JNS231326 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 2, 2024 Category: Neurosurgery Authors: Joseph H Ha Matthew T Borzage Erik B Vanstrum Eamon K Doyle Meenakshi Upreti Benita Tamrazi Marvin Nelson Stefan Bl üml Malkiat S Johal J Gordon McComb Jason Chu Susan Durham Mark D Krieger Rex A Moats Peter A Chiarelli Source Type: research
Monopolar stereoelectroencephalography-guided radiofrequency thermocoagulation
CONCLUSIONS: The use of monopolar SEEG-guided RFTC provides more freedom in terms of choosing the SEEG contacts for thermocoagulation and a larger thermolesion volume. Monopolar thermocoagulation seems particularly beneficial in cases with an insular EZ, in which vascular constraints could be partially avoided by making noncontiguous lesions within the EZ.PMID:38564812 | DOI:10.3171/2023.7.JNS23319 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 2, 2024 Category: Neurosurgery Authors: Krasimir T Minkin Kaloyan R Gabrovski Yoana T Milenova Petar A Karazapryanov Stanimir S Sirakov Petia S Dimova Source Type: research
Resection of the quadrangular lobule of the cerebellum to increase exposure of the cerebellomesencephalic fissure: an anatomical study with clinical correlation
CONCLUSIONS: QLC resection significantly increased the exposure area, mainly in the anteroposterior axis. This surgical strategy appears to be safe and may help the neurosurgeon when operating on the lateral aspect of the cerebellomesencephalic fissure.PMID:38564813 | DOI:10.3171/2023.7.JNS222838 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 2, 2024 Category: Neurosurgery Authors: Juan Leonardo Serrato-Avila Juan Alberto Paz Archila Alejandro Monroy-Sosa Sebastian An íbal Alejandro Marcos Devanir Silva da Costa Sergio Cavalheiro Kaan Yagmurlu Michael T Lawton Feres Chaddad-Neto Source Type: research
Minimally invasive keyhole approach for supramaximal frontal glioma resections: technical note
CONCLUSIONS: Keyhole approaches enabled successful SMR of frontal gliomas without added risks. Robust anatomical knowledge and meticulous surgical technique are paramount for obtaining successful resections.PMID:38564815 | DOI:10.3171/2023.7.JNS231363 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 2, 2024 Category: Neurosurgery Authors: Mart ín A Merenzon Mynor J Mendez Valdez Jay Chandar Victor M Lu Francisco Marco Del Pont Alexis A Morell Daniel G Eichberg Lekhaj Daggubati Carolina G Benjamin Ashish H Shah Michael E Ivan Ricardo J Komotar Source Type: research
Periprocedural intravenous heparin in patients with acute ischemic stroke treated with endovascular thrombectomy after intravenous thrombolysis
CONCLUSIONS: The results showed that periprocedural heparin is associated with an increased risk of unfavorable outcomes and SICH in patients treated with EVT after IVT. Further studies are warranted to evaluate the utility and safety of periprocedural heparin.PMID:38552231 | DOI:10.3171/2024.1.JNS232584 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Hao Wang Kang Yuan Xianjun Huang Yi Zhong Mengdi Xie Ruidong Ye Yunfei Han Qiushi Lv Qingshi Zhao Rui Liu Source Type: research
Epidemiology of moderate traumatic brain injury and factors associated with poor neurological outcome
CONCLUSIONS: Almost half of the patients with moderate TBI had poor neurological outcome at hospital discharge. Several factors including older age, higher CCI, GCS scores of 9 or 10, severe trauma, and mechanical ventilation or craniotomy were found to be associated with poor neurological outcome in patients with moderate TBI. Additionally, these data suggest that tranexamic acid administration and admission to the ICU might be important for improving prognosis. Further investigations are warranted to elucidate the appropriate management for patients with moderate TBI.PMID:38552232 | DOI:10.3171/2024.1.JNS232627 (Source: ...
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Shu Utsumi Shingo Ohki Nobuaki Shime Source Type: research
Are hemodynamics responsible for inflammatory changes in venous vessel walls? A quantitative study of wall-enhancing intracranial arteriovenous malformation draining veins
CONCLUSIONS: This novel multimodal investigation of hemodynamics in AVM draining veins allows for precise prediction of occurring shear- and flow-related phenomena in enhanced vessel walls. These findings may suggest low shear to be a local predisposing factor for venous stenosis in AVMs.PMID:38552234 | DOI:10.3171/2024.1.JNS232625 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Janneck Stahl Laura Stone McGuire Mark Rizko Sylvia Saalfeld Philipp Berg Ali Alaraj Source Type: research
Association of frequent NF2 mutations with spinal location predominance and worse outcomes in psammomatous meningiomas
CONCLUSIONS: Female sex and spinal location predominance were statistically significant in PMs. NF2 mutation was an independent predictor for worse PFS of PMs. Of note, NF2 mutation was detected in all SPMs but in only 38.46% of CPMs, revealing a significant difference.PMID:38552238 | DOI:10.3171/2024.1.JNS232450 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Leihao Ren Qing Xie Jiaojiao Deng Jiawei Chen Jinxiu Yu Daijun Wang Hiroaki Wakimoto Ye Gong Lingyang Hua Source Type: research
Molecularly targeted protease-activated probes for visualization of glioblastoma: a comparison with 5-ALA
CONCLUSIONS: The cysteine cathepsin-cleavable probe 6QC-ICG is activated by glioma cells and tumor-associated macrophages, leading to a high contrast between tumor and nontumorous brain tissue that is superior to that of the current standard, 5-ALA. In addition to a well-defined mechanism of action, protease-activated probes that use NIR fluorophores (e.g., indocyanine green) have the advantage of low absorption and scattering of the NIR light and lower tissue autofluorescence. These results suggest that 6QC-ICG has the potential to become the targeted agent in intraoperative detection of GBM tissue using fluorescence imag...
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Dora Kone čná Petr V ýmola Nikola Ternerov á Barbora V ýmolová Elena Garcia-Borja Rosana Mateu Filip Šroubek Jan Pankr ác John C Widen Matthew Bogyo David Netuka Petr Bu šek Aleksi Šedo Source Type: research
Deep learning-based quantification of total bleeding volume and its association with complications, disability, and death in patients with aneurysmal subarachnoid hemorrhage
CONCLUSIONS: Elevated TBV is associated with a greater risk of hydrocephalus, rebleeding, death, and poor prognosis.PMID:38552240 | DOI:10.3171/2024.1.JNS232280 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 29, 2024 Category: Neurosurgery Authors: Ping Hu Yanze Wu Tengfeng Yan Lei Shu Feng Liu Bing Xiao Minhua Ye Miaojing Wu Shigang Lv Xingen Zhu Source Type: research
