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Condition: Ataxia

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Total 492 results found since Jan 2013.

Creutzfeldt-Jakob and Vascular Brain Diseases: Their Overlap and Relationships
In conclusion, a complex of clinical, radiological, and laboratory manifestations of stroke-like onset of CJD is outlined. The clinical relationships between CJD and stroke are considered, in an attempt to highlight this rare presentation of an uncommon disease.
Source: Frontiers in Neurology - February 25, 2021 Category: Neurology Source Type: research

Severe heat stroke complicated by multiple cerebral infarctions: a case report
ConclusionsEarly management of heat stroke using anti-DIC, anti-bacterial, and fluid resuscitation therapy can help prevent complications such as intracranial hemorrhaging.
Source: Journal of Medical Case Reports - January 28, 2021 Category: General Medicine Source Type: research

Predictive Validity of the Scale for the Assessment and Rating of Ataxia for Medium-Term Functional Status in Acute Ataxic Stroke
This study examines the prognostic validity of the Scale for the Assessment and Rating of Ataxia for patients with acute stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - January 25, 2021 Category: Neurology Authors: Kota Yamauchi, Kenichi Kumagae, Kei Goto, Risa Hagiwara, Yoshiko Uchida, Eisei Harayama, Shota Tanaka, Sota Kuroyama, Yasuhiro Koyanagi, Shuji Arakawa Source Type: research

Who is really blind in the time of coronavirus: the patient or the doctor? A rare case of Balint ’s syndrome
ConclusionDuring SARS-CoV2 pandemic, Italian physicians were forced to work with less instrumental diagnostic resources, relying on their clinical knowledge mostly. The aim of this case report is to highlight the importance of performing a precise neurological evaluation, particularly during these challenging times: it might avoid incorrect diagnosis and favour the discovery of rare clinical diseases.
Source: Neurological Sciences - January 5, 2021 Category: Neurology Source Type: research

COVID-19 may also invade the central nervous system, cause neurological illnesses
(Cleveland Clinic) COVID-19 is known primarily as a respiratory disease, with symptoms that include cough, shortness of breath, and, in severe cases, acute respiratory distress syndrome and pneumonia. Now, Cleveland Clinic researchers note in a recent review that infection with the coronavirus may also affect the central nervous system and cause corresponding neurological disorders, including ischemic stroke, encephalitis, encephalopathy and epileptic seizures.According to the review published in Cells, the symptoms of COVID-19-related neurological manifestations include dizziness, headache, a loss of consciousness and ataxia.
Source: EurekAlert! - Infectious and Emerging Diseases - December 10, 2020 Category: Infectious Diseases Source Type: news

The impact of body mass index on functional rehabilitation outcomes of working-age inpatients with stroke.
CONCLUSIONS: FIM outcomes were not associated to BMI, nevertheless each BMI category when individually considered (normal weight, overweight or obese) was characterized by different associations involving FIM outcomes and clinical factors. CLINICAL REHABILITATION IMPACT: In sub-acute post-stroke working-age patients undergoing rehabilitation, BMI was not associated to FIM outcomes (no obesity paradox was reported in this sample). Distinctive significant associations emerged within each BMI category, (supporting their characterization) such as length of stay and TFIM effectiveness were associated for normal weight and ...
Source: European Journal of Physical and Rehabilitation Medicine - December 2, 2020 Category: Rehabilitation Authors: Garcia-Rudolph A, Kelleher JD, Cegarra B, Saurí Ruiz J, Nedumpozhimana V, Opisso E, Tormos JM, Bernabeu M Tags: Eur J Phys Rehabil Med Source Type: research

Gasperini Syndrome: A Case Report and Systematic Review and Proposing a New Definition
We report a new case and reviewed the clinical features of this syndrome from all published reports to propose a new definition. A 57-year-old man with acute br ainstem stroke had right CN V–VIII and XII palsies, left body hypoesthesia and ataxia. Brain MRI showed an acute stroke in the right caudal pons and bilateral cerebellum. After a systematic review, we classified the clinical manifestations into core and associate features based on the frequencies of occurring neurological deficits. We propose that a definitive GS requires the presence of ipsilateral CN VI and VII palsies, plus one or more of the other three core ...
Source: Case Reports in Neurology - November 13, 2020 Category: Neurology Source Type: research

The role of Nrf2 in Neural stem/Progenitors cells: from maintaining stemness and self-renewal to promoting differentiation capability and facilitating therapeutic application in neurodegenerative disease.
Abstract Neurodegenerative diseases (NDs) cause progressive loss of neurons in nervous system. NDs are categorized as acute NDs such as stroke and head injury, besides chronic NDs including Alzheimer's, Parkinson's, Huntington's diseases, Friedreich's Ataxia, Multiple Sclerosis. The exact etiology of NDs is not understood but oxidative stress, inflammation and synaptic dysfunction are main hallmarks. Oxidative stress leads to free radical attack on neural cells which contributes to protein misfolding, glia cell activation, mitochondrial dysfunction, impairment of DNA repair system and subsequently cellular death. ...
Source: Ageing Research Reviews - November 10, 2020 Category: Genetics & Stem Cells Authors: Kahroba H, Ramezani B, Maadi H, Sadeghi MR, Jaberie H, Ramezani F Tags: Ageing Res Rev Source Type: research

A unique finding of the basilar artery
AbstractVariants of the posterior intracranial circulation are important for surgeon, interventionalists and radiologists. Herein, a unique configuration of the basilar artery is reported. A 54-year-old man with a history of COPD, hypothyroidism, smoking, and hyperlipidemia presented to an outside institution with nausea, confusion, altered mental status, and ataxia. The patient was evaluated for stroke. Imaging revealed rotation of the basilar apex of 180 degrees, fetal configuration of the posterior communicating artery, right posterior cerebral artery filling from the left vertebral artery, and duplication of the left a...
Source: Surgical and Radiologic Anatomy - November 1, 2020 Category: Anatomy Source Type: research

Clinical Manifestations of Copper Deficiency: A Case Report and Review of the Literature.
CONCLUSIONS: Our patient presented with copper deficiency secondary to malabsoprtion. This case highlights the importance of copper testing in the bariatric surgery population and in patients with short-bowel syndrome. Given the irreversible nature of neurological symptoms when compared with the expense of nutrition supplements, routine copper testing should be considered in patients with malabsorptive states or altered anatomy, regardless of initial presentation. PMID: 33037701 [PubMed - as supplied by publisher]
Source: Nutrition in Clinical Practice - October 9, 2020 Category: Nutrition Authors: Moon N, Aryan M, Westerveld D, Nathoo S, Glover S, Kamel AY Tags: Nutr Clin Pract Source Type: research

Clinical observation of acupuncture plus Frenkel exercises for ataxia after cerebral stroke
ConclusionMind-refreshing and balance-restoring needling can effectively improve the lower-limb ataxic symptoms and ADL after stroke; when combined with Fenkel exercises, this needling method can produce more significant efficacy.
Source: Journal of Acupuncture and Tuina Science - October 1, 2020 Category: Complementary Medicine Source Type: research

Progressive ataxia and cognitive decline in a 67-year-old male: a diagnostic challenge.
We report the case of a 67-year-old male who presented with a six-week history of progressive unsteadiness, cognitive impairment and weight loss, in the context of a recent bereavement. Magnetic resonance imaging (MRI) performed several weeks earlier excluded acute stroke. Examination revealed gross bilateral ataxia, bradyphrenia and physical manifestations of depression. Collateral history suggested rapidly progressing symptoms over three months. Repeat MRI head showed features suggestive of Creutzfeldt-Jakob disease (CJD) including T2 hyperintensities in the basal ganglia. Cerebrospinal ˜fluid (CSF) samples were positiv...
Source: Journal of the Royal College of Physicians of Edinburgh - September 17, 2020 Category: General Medicine Tags: J R Coll Physicians Edinb Source Type: research

CADASIL vs. Multiple Sclerosis: Is It Misdiagnosis or Concomitant? A Case Series
Conclusion: Since CADASIL is a rare disease, it is imperative to raise awareness of its unique clinical condition as well as variation in its clinical presentations. It is crucial that the overlapping symptoms between MS and CADASIL be thoroughly examined to avoid misdiagnosis and treatment complications. The involvement of autoimmune mechanisms in CADASIL and the role of NOTCH3 gene mutations in provoking an autoimmune process should be further investigated.
Source: Frontiers in Neurology - September 3, 2020 Category: Neurology Source Type: research

Predicting independence of gait by assessing sitting balance through sitting posturography in patients with subacute hemiplegic stroke.
CONCLUSIONS: Sitting posturography parameters is clinically useful because they can quantitatively assess post-stroke balance and neurological impairment and predict post-stroke independence of gait even when patients cannot reach their arms forward or stand upright. PMID: 32783510 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - August 11, 2020 Category: Neurology Authors: Lee HH, Lee JW, Kim BR, Jung HJ, Choi DH, Lee J Tags: Top Stroke Rehabil Source Type: research

Ataxia Associated with CADASIL: a Pathology-Confirmed Case Report and Literature Review
AbstractCerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is primarily characterized by migraine, stroke, mood disturbances, and cognitive decline. Ataxia has seldom been reported as a presenting symptom. Here, we review reports of CADASIL presenting as ataxia and compare these to the first pathologically confirmed case of CADASIL presenting with progressive ataxia. A 50-year-old woman presented with progressive truncal ataxia. Brain magnetic resonance imaging (MRI) revealed white matter hyperintensities in the bilateral anterior temporal lobes, external capsules, and peri...
Source: The Cerebellum - July 29, 2020 Category: Neurology Source Type: research