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Condition: Ataxia

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Total 492 results found since Jan 2013.

Sex Equitable Prehospital Stroke Triage Using Symptom Severity and Teleconsultation
Conclusions: The SSTS had equal predictive performance for LAO and EVT among men and women, despite minor sex differences in the clinical characteristics in patients undergoing ambulance transport for suspected stroke.
Source: Frontiers in Neurology - November 29, 2021 Category: Neurology Source Type: research

Dorsal Midbrain Syndrome: Clinical and Imaging Features in 75 Cases
Conclusions: This large series expands on the clinical profile of DMS. Neoplasms and strokes were the most common causes. Obstructive hydrocephalus alone, identified as a major cause in the largest previously published series, was uncommon. At least 3 neuro-ophthalmic signs were present in nearly all patients, with upgaze deficit as predominant. Unlike an earlier report, this study found no correlation between brain imaging and clinical signs. Neuro-ophthalmic signs persisted even after neoplasms were successfully treated and improved only slightly after stroke. Telephone interviews with patients revealed that diplopia...
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

Vertebral artery thrombosis in a 7-year-old child
We present the case history of a 7-year-old boy who was admitted to the pediatric intensive care unit of a county hospital with symptoms of facial palsy, progrediating ataxia and somnolence. Contrast-enhanced angiographic MR images of the skull revealed acute ischemic lesions and suggested stenosis of the left vertebral artery, then it was confirmed by TOF (time of flight) angiography of vessels of the neck and cervical ultrasound examination. The arterial thrombus causing ischaemia was eliminated by drug treatment and the rehabilitation process could be started. The patient's condition improved considerably following that...
Source: Orvosi Hetilap - November 21, 2021 Category: General Medicine Authors: Alexandra Viczei Istv án Lapis Ádám Marián Brzózka Gy örgy Szeifert Source Type: research

Arteria vertebralis thrombosis egy 7 éves gyermekben
We present the case history of a 7-year-old boy who was admitted to the pediatric intensive care unit of a county hospital with symptoms of facial palsy, progrediating ataxia and somnolence. Contrast-enhanced angiographic MR images of the skull revealed acute ischemic lesions and suggested stenosis of the left vertebral artery, then it was confirmed by TOF (time of flight) angiography of vessels of the neck and cervical ultrasound examination. The arterial thrombus causing ischaemia was eliminated by drug treatment and the rehabilitation process could be started. The patient's condition improved considerably following that...
Source: Orvosi Hetilap - November 21, 2021 Category: General Medicine Authors: Alexandra Viczei Istv án Lapis Ádám Marián Brzózka Gy örgy Szeifert Source Type: research

Vertebral artery thrombosis in a 7-year-old child
We present the case history of a 7-year-old boy who was admitted to the pediatric intensive care unit of a county hospital with symptoms of facial palsy, progrediating ataxia and somnolence. Contrast-enhanced angiographic MR images of the skull revealed acute ischemic lesions and suggested stenosis of the left vertebral artery, then it was confirmed by TOF (time of flight) angiography of vessels of the neck and cervical ultrasound examination. The arterial thrombus causing ischaemia was eliminated by drug treatment and the rehabilitation process could be started. The patient's condition improved considerably following that...
Source: Orvosi Hetilap - November 21, 2021 Category: General Medicine Authors: Alexandra Viczei Istv án Lapis Ádám Marián Brzózka Gy örgy Szeifert Source Type: research

Stroke-like lesions in mitochondrial disease may resemble ischemic stroke
J Family Med Prim Care. 2021 Aug;10(8):3151-3153. doi: 10.4103/jfmpc.jfmpc_2314_20. Epub 2021 Aug 27.ABSTRACTThe patient is a 73-y-male who was referred after a fall without losing consciousness or secessus. Clinical exam revealed disorientation, ophthalmoparesis, hemianopia to the left, left hemineglect, hypoacusis, quadruparesis, general wasting, generally reduced tendon reflexes, mild rigor, occasional myoclonic jerks of the right lower limb, and ataxia of the left lower limb. Cerebral magnetic resonance imaging (MRI) showed a stroke-like lesion (SLL), generalized atrophy, white matter lesions, and ponsgliosis. The prev...
Source: Primary Care - October 18, 2021 Category: Primary Care Authors: Josef Finsterer Source Type: research

Gene Therapy Approach with an Emphasis on Growth Factors: Theoretical and Clinical Outcomes in Neurodegenerative Diseases
This article mainly focuses on the delivering modes of genetic materials in the CNS, which includes viral and non-viral vectors and their application in gene therapy. Despite the many clinical trials conducted so far, data have shown disappointing outcomes. The efforts done to improve outcomes, efficacy, and safety in the identification of targets in various neurological disorders are also discussed here. Adapting gene therapy as a new therapeutic approach for treating neurological disorders seems to be promising, with early detection and delivery of therapy before the neuron is lost, helping a lot the development of new t...
Source: Molecular Medicine - October 16, 2021 Category: Molecular Biology Authors: Della Grace Thomas Parambi Khalid Saad Alharbi Rajesh Kumar Seetha Harilal Gaber El-Saber Batiha Nat ália Cruz-Martins Omnia Magdy Arafa Musa Dibya Sundar Panda Bijo Mathew Source Type: research

Severe chickenpox disease and seroprevalence in Sweden – implications for general vaccination
Chickenpox is the clinical manifestation of primary infection with varicella zoster virus (VZV) and a mild disease in the vast majority of cases. However, complications occur, primarily bacterial infections of vesicles, sometimes with deeper infection and sepsis, as well as neurological complications; e.g. encephalitis, meningitis, or classically acute cerebellitis with ataxia. Rare complications such as pneumonitis, hepatitis and haemorrhagic complications may occur (Gershon et al., 2018). There is even an increased risk of stroke in the time period 6 months after a chickenpox episode (Thomas et al., 2014).
Source: International Journal of Infectious Diseases - August 8, 2021 Category: Infectious Diseases Authors: K Widgren, L Persson Berg, A M örner, L Lindquist, A Tegnell, J Giesecke, M Studahl Source Type: research

Progressive Ataxia and Downbeat Nystagmus in an Adult
A 63-year-old man presented with a history of vomiting, hypertension, dyslipidemia, type 2 diabetes, dilated ischemic cardiomyopathy, alcohol use, and stroke; physical examination found appendicular dysmetria with truncal ataxia and downbeat nystagmus. Brain magnetic resonance imaging revealed a hyperintensity on T2-weighted and fluid-attenuated inversion recovery sequences without reduced diffusion in the cerebellar nodule. What is your diagnosis?
Source: JAMA Neurology - August 1, 2021 Category: Neurology Source Type: research

Stroke-like episodes with cerebellar ataxia as presenting manifestation of adult-onset anti-N-methyl d-aspartate receptor encephalitis: an unusual presentation
Source: Acta Neurologica Belgica - July 3, 2021 Category: Neurology Source Type: research