A Surgical Approach to Orbitotomy Using the Bone Scalpel: A Case Report
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Surgeons' Corner Source Type: research

Dizziness and Vertigo: The Skillful Examination
Conclusion: By applying a methodical approach to examination of patients with dizziness and vertigo, localization of the offending lesion, management, and even elucidation of the underlying diagnosis is feasible. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Trainees' Corner Source Type: research

Neuro-Ophthalmic Manifestations of Intracranial Malignancies
Conclusion: Intracranial malignancies can present with neuro-ophthalmic symptoms or signs depending on topographical localization. Specific neuro-ophthalmic presentations are associated with different malignant intracranial tumors. Clinicians should be aware of the common malignant intracranial tumors and their associated clinical presentations in neuro-ophthalmology. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Trainees' Corner Source Type: research

The 2020 Update to North American Neuro-Ophthalmology Society's (NANOS) Neuro-Ophthalmology Curriculum
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Neuro-Ophthalmology News Source Type: research

The 46th Annual Meeting of the North American Neuro-Ophthalmology Society in Amelia Island, Florida
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Neuro-Ophthalmology News Source Type: research

Drs. Richard John Leigh and David Zee
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Great Conversations Source Type: research

In Memoriam: Richard “Dick” Mills, MD, MPH
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: In Memoriam Source Type: research

Should a Hypercoagulable Workup Be Performed on Young Patients with Nonarteritic Anterior Ischemic Optic Neuropathy?: Response
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Prothrombin G20210A Mutation Causing Nonarteritic Anterior Ischemic Optic Neuropathy in a Young Patient
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Going Back One Car in the Train: Evaluation of the Relative Afferent Pupillary Defect in the Era of Tele–Neuro-Ophthalmology
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Literature Commentary
In this issue of Journal of Neuro-Ophthalmology, M. Tariq Bhatti, MD, and Mark L. Moster, MD will discuss the following 6 articles: (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Literature Commentary Source Type: research

Should Aspirin Be Prescribed to Prevent Recurrence in Nonarteritic Anterior Ischemic Optic Neuropathy?
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Point Counter-Point Source Type: research

Clinicopathological Correlates: Chronic Arsenic Toxicity Causing Bilateral Symmetric Progressive Optic Neuropathy
Abstract: A 70 year-old man presented with insidiously progressing central visual acuity loss in both eyes over several years. Objectively the only abnormality identified on the exam was questionable granularity in the fovea in each eye. Extensive work up which included neuro-imaging, screening blood work for toxic and nutritional causes of optic neuropathy as well as electroretinogram and fluorescein angiography to rule out subtle maculopathy was all unrevealing. When vision continued to deteriorate over the next several years investigations were repeated and again did not yield any positive results. Levels of heavy met...
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Clinical-Pathological Case Study Source Type: research

Rapidly Sequential Vision Loss From Posterior Ischemic Optic Neuropathy Due to Methicillin-Susceptible Staphylococcus Aureus Bacteremia
Abstract: A 63-year-old man with a history of high-grade bladder cancer was admitted to the intensive care unit (ICU) with renal failure and methicillin-susceptible Staphylococcus aureus bacteremia originating from his nephrostomy tube. While in the ICU, he had painless, severe loss of vision in the right eye followed by his left eye 12 hours later. Visual acuity was no light perception in each eye. He was anemic, and before each eye lost vision, there was a significant decrease in blood pressure. Dilated fundus examination was normal, and MRI showed hyperintense signal in the bilateral intracanalicular optic nerves on d...
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Photo Essay Source Type: research

Remote Pontine Hemorrhage After Left Frontal Lobe Meningioma Resection Presenting as Bilateral Internuclear Ophthalmoplegia
We describe a bilateral internuclear ophthalmoplegia due to an RPH after otherwise uncomplicated resection of a frontal meningioma. Clinicians should be aware that neuro-ophthalmic findings can occur from hemorrhages remote from the operative site. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Photo Essay Source Type: research

Fourth Nerve Palsy Due to Neurocysticercosis
We describe a patient with a unilateral fourth nerve palsy, a rare presentation of neurocyticercosis. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Photo Essay Source Type: research

A Rare Mutation Associated With Probable Late-Onset Leber's Hereditary Optic Neuropathy
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Novel Mitochondrial Translation Optimizer-1 Mutations as a Cause of Hereditary Optic Neuropathy
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Severe Bilateral Vision Loss in 2 Patients With Coronavirus Disease 2019
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Myelin Oligodendrocyte Glycoprotein Antibody–Associated Optic Neuritis and Myelitis in COVID-19
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Neuro-Ophthalmic Features of Autoimmune Encephalitides
Conclusions: The novel cell-surface protein-directed autoimmune encephalitis group can present with a wide range of afferent and efferent neuro-ophthalmic manifestations. Neuro-ophthalmologists should be familiar with these antibody-associated syndromes, which are treatable and often require a high index of suspicion for diagnosis. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: State-of-the-Art Review Source Type: research

Tele–Neuro-Ophthalmology: Vision for 20/20 and Beyond
Conclusions: Telehealth is an increasingly recognized means of health care delivery. Tele–Neuro-Ophthalmology adoption is necessary for the sake of our patients, the survival of our subspecialty, and the education of our trainees and students. Telehealth does not supplant but supplements and complements in-person neuro-ophthalmologic care. Innovations in digital optical fundus photography, mobile vision testing applications, artificial intelligence, and principles of channel management will facilitate further adoption of tele–neuro-ophthalmology and bring the specialty to the leading edge of health care deliv...
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: State-of-the-Art Review Source Type: research

Neurocognitive Assessment and Retinal Thickness Alterations in Alzheimer Disease: Is There a Correlation?
Background: The relation of retinal thickness to neuropsychological indexes of cognitive impairment in patients with Alzheimer disease (AD) remains an area of investigation. The scope of this investigation was to compare volume and thickness changes of neuronal retinal layers in subjects with AD with those of age-matched healthy controls and to estimate the relation between cognitive functioning evaluated by neuropsychological assessment and thickness changes of the retina. Methods: This was a prospective single-site study where we evaluated 25 subjects with probable AD matched for age, sex, and education to 17 health...
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Original Contribution Source Type: research

Causes of Horner Syndrome: A Study of 318 Patients
Conclusions: The prevalence of causes of Horner syndrome depends on the accrual method. Among pharmacologically-confirmed cases, the cause was often undetermined or due to a preceding neck or chest procedure. Among pharmacologically-unconfirmed cases, a substantial proportion had also been caused by neck and chest procedures, but tumors in that region were also common. When a cause of Horner syndrome was found in both cohorts, it was usually known before Horner syndrome was discovered, making Horner syndrome an afterthought. However, in an important minority of cases where the cause was not yet known, the identification ...
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Original Contribution Source Type: research

Optic Disc Drusen Associated Anterior Ischemic Optic Neuropathy: Prevalence of Comorbidities and Vascular Risk Factors
Conclusions: In this cross-sectional study, the ODD-AION patients more often had no vascular risk factors as compared to NA-AION patients, which supports the hypothesis that ODD are an independent risk factor for AION. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Original Contribution Source Type: research

Survey of Telehealth Adoption by Neuro-ophthalmologists During the COVID-19 Pandemic: Benefits, Barriers, and Utility
Background: During the COVID-19 pandemic, telehealth modalities have come to prominence as a strategy for providing patient care when in-person care provision opportunities are limited. The degree of adoption by neuro-ophthalmologists has not been quantified. Methods: Telehealth utilization pre–COVID-19 and peri–COVID-19 was surveyed among practicing neuro-ophthalmologists in and outside the United States using an online platform. Demographics, perceived benefits, barriers, and utility for different neuro-ophthalmic conditions were collected. Data collection occurred over a 2-week period in May 2020. Resu...
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Original Contribution Source Type: research

Thrombolysis for Central Retinal Artery Occlusion in 2020: Time Is Vision!
Conclusions: In 2020, nonarteritic CRAO patients should theoretically receive the same thrombolytic therapies, in the same time window, as patients with acute cerebral ischemia. Eye stroke and teleeye stroke code encounters must include an expert ophthalmologic evaluation to confirm the correct diagnosis and to evaluate for ocular signs that may help guide IV tPA administration or IA management. Future research should focus on developing feasible retinal penumbra imaging studies that, similar to cerebral tissue viability or perfusion imaging, can be incorporated into the thrombolysis decision-making algorithm. (Source: J...
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Disease of the Year: Cerebrovascular Disorders Source Type: research

Stroke Rate, Subtype, and Cardiovascular Risk Factors in Nonarteritic Anterior Ischemic Optic Neuropathy: A Population-Based Study
Conclusions: NAION does not confer an increased risk of symptomatic stroke beyond the risk posed by age and existing vascular risk factors. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Clinical Research: Epidemiology Meets Neuro-Ophthalmology Source Type: research

Neuro-Ophthalmic Injuries With Systemic Neurologic Injury or Traumatic Brain Injury in Operation Iraqi Freedom and Operation Enduring Freedom
Background: To analyze the final visual acuity (VA) of neuro-ophthalmologic injuries (NOI) in combat ocular trauma and to study the association of NOI with systemic neurologic injury (SNI) and traumatic brain injury (TBI). Methods: The Walter Reed Ocular Trauma Database was reviewed. Inclusion criteria were any US service member and Department of Defense civilians who suffered NOI, SNI, or TBI in Operation Iraqi Freedom or Operation Enduring Freedom. The primary outcome measure was the rate of poor final VA in patients with an NOI with secondary outcome measures the rate of SNI and TBI. in patients with NOI. Results:...
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Clinical Research: Epidemiology Meets Neuro-Ophthalmology Source Type: research

Progression Over 5 Years of Prelaminar Hyperreflective Lines to Optic Disc Drusen in the Copenhagen Child Cohort 2000 Eye Study
Background: The purpose of the study was to examine 5-year changes in eyes with optic disc drusen at baseline on optical coherence tomography (OCT) scans and the relation of incident drusen to hyperreflective prelaminar lines. Methods: The study included children who presented at baseline, when participants were aged 11–12 years, and again 5 years later. Grading for optic disc drusen was made in all. Grading for prelaminar lines was made in all children at follow-up and in eyes with optic disc drusen at baseline. Analyses included associations with scleral canal diameter at baseline in all children with optic di...
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Clinical Research: Epidemiology Meets Neuro-Ophthalmology Source Type: research

Considerations for the Treatment of Inflammatory Neuro-Ophthalmologic Disorders During the COVID-19 Pandemic
Abstract: The initiation and continuation of immune-based therapies to treat and prevent complications of inflammatory neuro-ophthalmologic disorders during the 2019 novel coronavirus (COVID-19) pandemic is the subject of considerable debate. In each case, a treatment decision must be reached based on best clinical practices for the disorder, patient comorbidities, the current state of knowledge about the pathogenesis and infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and the utilization of hospital and community resources. Unfortunately, the evidence needed to standardize the decision-makin...
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Perspective Source Type: research

Tele-Neuro-Ophthalmology During the Age of COVID-19
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Perspective Source Type: research

Review of Cohort Studies: A Companion Article to Malmqvist et al “Progression Over 5 Years of Prelaminar Hyperreflective Lines to Optic Disc Drusen in the Copenhagen Child Cohort 2000 Eye Study”
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Editorial Source Type: research

New Initiatives at Journal of Neuro-Ophthalmology: Highlighting Technology, Social Media, and Content for Trainees
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Editorial Source Type: research

Disease of the Year: COVID-19 and Its Neuro-ophthalmic Complications
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Editorial Source Type: research

Checkerboard Visual Field Defect in Occipital Stroke
Abstract: A 74-year-old man with vasculopathic risk factors presented to the emergency room with a chief complaint of peripheral vision loss resulting from an intracranial hemorrhage in his right parietal and occipital lobes. Urgent craniotomy and ventriculostomy led to a stable clinical condition with subsequent development of a crossed quadrant homonymous hemianopsia (checkerboard visual field) due to a new right parieto-occipital infarct superimposed on a prior left occipital infarct. This uncommon visual field defect represents juxtaposed homonymous quadrantanopias that produce a striking checkerboard appearance that...
Source: Journal of Neuro-Ophthalmology - May 19, 2020 Category: Opthalmology Tags: Trainees' Corner Source Type: research

Corneal Neurotization: A Surgical Treatment for Neurotrophic Keratopathy
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - May 19, 2020 Category: Opthalmology Tags: Surgeons' Corner Source Type: research

European Neuro-Ophthalmology Society Meeting, June 16–19, 2019, Porto, Portugal
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - May 19, 2020 Category: Opthalmology Tags: Neuro-Ophthalmology News Source Type: research

Klara Landau's Retirement From University Chair and European Neuro-Ophthalmology Society 2018 Course Both Occur in Switzerland
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - May 19, 2020 Category: Opthalmology Tags: Neuro-Ophthalmology News Source Type: research

The Eyes Give Warning
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - May 19, 2020 Category: Opthalmology Tags: Historical Note Source Type: research

Literature Commentary
In this issue of Journal of Neuro-Ophthalmology, M. Tariq Bhatti, ND and Mark L. Moster, MD will discuss the following 6 articles: (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - May 19, 2020 Category: Opthalmology Tags: Literature Commentary Source Type: research

Aspirin Should Not Be Recommended to Prevent Second Eye Involvement in Patients With Nonarteritic Anterior Ischemic Optic Neuropathy
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - May 19, 2020 Category: Opthalmology Tags: Point Counter-Point Source Type: research

Episodic Visual Distortions and Stroke-Like Symptoms in a 56-Year-Old Man With Intravascular Lymphoma
Abstract: A healthy 56-year-old man presented with vision changes and left upper extremity motor and sensory changes. MRI of the brain without contrast was significant for multifocal areas of restricted diffusion in multiple vascular territories. Neuro-Ophthalmic evaluation revealed an inferonasal visual field defect in the left eye, thickened choroid on optical coherence tomography, and bilateral delayed arteriovenous and choroidal filling on fluorescein angiogram. Repeat MRI demonstrated interval enlargement of many of the same foci of abnormal diffusion-weighted imaging signal. Computed tomography of the abdomen and p...
Source: Journal of Neuro-Ophthalmology - May 19, 2020 Category: Opthalmology Tags: Clinical-Pathological Case Study Source Type: research

Familial Cavernous Hemangioma
Abstract: A 30-year-old woman presented with diplopia after resection of an intracranial cavernous malformation. Fundus examination showed an asymptomatic intraocular cavernous hemangioma of the retina. Clinicians should be aware of the potential coexistence of intraocular and intracranial cavernous malformations; the presence of both should suggest familial etiology. As with other intracranial and intraocular vascular lesions (e.g., arteriovenous malformation in Wyburn-Mason syndrome, retinal hemangioblastoma in von Hippel Lindau disease, and choroidal hemangioma in Sturge–Weber syndrome), the presence of a vascul...
Source: Journal of Neuro-Ophthalmology - May 19, 2020 Category: Opthalmology Tags: Photo Essay Source Type: research

Toxic Optic Neuropathy From Quinine Overdose
We present a patient with the stereotypical findings and natural history of quinine toxicity, a rare and not widely known cause of toxic optic neuropathy and retinopathy. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - May 19, 2020 Category: Opthalmology Tags: Photo Essay Source Type: research

Isolated Optic Perineuritis as the Presenting Sign of Sarcoidosis
Abstract: A 35-year-old healthy African-American woman presented with a 4-month history of gradual loss of vision in the right eye from an optic neuropathy. MRI of the orbits with gadolinium showed isolated thickening and enhancement of the right optic nerve sheath. Chest x-ray and CT-scan of the chest were performed and showed bilateral hilar and mediastinal lymphadenopathy. This was suggestive of sarcoidosis, and the diagnosis was confirmed with histopathology. The patient promptly recovered vision with high-dose corticosteroids; the thickening of the optic nerve sheath also regressed. Isolated optic nerve sheath thick...
Source: Journal of Neuro-Ophthalmology - May 19, 2020 Category: Opthalmology Tags: Photo Essay Source Type: research

Jugular Paraganglioma and Bilateral Vestibular Schwannoma Presenting to an Acute Ophthalmology Service
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - May 19, 2020 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Paroxysmal Adduction After Internuclear Ophthalmoplegia
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - May 19, 2020 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Fulminant Pseudotumor Cerebri Syndrome Secondary to Over-the-Counter Topical Retinoids
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - May 19, 2020 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Recurrent Bilateral Myelin Oligodendrocyte Glycoprotein Antibody Optic Neuritis in a Leber Hereditary Optic Neuropathy Carrier
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - May 19, 2020 Category: Opthalmology Tags: Clinical Correspondence Source Type: research