Comments on Disorders of the Fourth Cranial Nerve: Response
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Comments on Disorders of the Fourth Cranial Nerve
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Neuro-Ophthalmologic Monitoring of Leaking Arachnoid Cysts
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Acute Posterior Multifocal Placoid Pigment Epitheliopathy Complicated by Fatal Cerebral Vasculitis: Response
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Acute Posterior Multifocal Placoid Pigment Epitheliopathy Complicated by Fatal Cerebral Vasculitis
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Letters to the Editor Source Type: research

Papilledema in a Patient Being Treated for Multiple Sclerosis
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: UPFRONT Case Source Type: research

Subacute Bilateral Vision Loss
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: UPFRONT Case Source Type: research

Surgical Outcomes of Transposition Surgery for the Correction of Large-Angle Strabismus
Background: Many potential surgical options exist to address large-angle deviations and head turns that result from various forms of paralytic strabismus. Muscle transposition surgeries serve as suitable alternatives to simple resection–recessions. Here, we report outcomes of augmented Hummelsheim and X-type transpositions for the correction of large-angle strabismus and provide insights for surgical planning. Methods: We performed a retrospective chart review of 40 consecutive patients with strabismus who were treated with an augmented Hummelsheim or X-type transposition surgery at a single academic medic...
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Surgeons' Corner Source Type: research

Contralateral Ocular Manifestations of a Carotid Cavernous Fistula Associated With Primitive Persistent Trigeminal Artery
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Trainees’ Corner Source Type: research

Leukemic and Lymphomatous Optic Neuropathy: A Case Series
Conclusions: Leukemic and lymphomatous optic neuropathy is difficult to diagnose and treat, and there is no gold standard for diagnosis or treatment in the current literature. We help clarify how this disease should be approached in a multidisciplinary fashion and on an individual basis to correctly diagnose and treat the vision loss, while considering the patient's long-term prognosis based on their systemic disease. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Trainees’ Corner Source Type: research

Myelin Oligodendrocyte Glycoprotein Antibody–Associated Optic Neuritis—A Review
Abstract: Our understanding of demyelinating optic neuritis has substantially evolved over the past 2 decades. With advancements in serological testing, antibodies against myelin oligodendrocyte glycoprotein (MOG) have been recently discovered in a distinct subset of demyelinating neuroinflammatory disease. Although MOG-immunoglobulin G (IgG)–associated disorder (MOGAD) has previously been seen as a component of neuromyelitis optica spectrum disorder (NMOSD), evidence increasingly suggests that it should be distinguished as a separate condition. The distinction of MOGAD from aquaporin-4 IgG NMOSD is imperative as...
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Trainees’ Corner Source Type: research

International Headache Society September 8–12, 2021
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Neuro-Ophthalmology News Source Type: research

A Great Conversation With Dr. Valerie Purvin
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Great Conversations Source Type: research

A Great Conversation With Dr. Shirley Wray
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Great Conversations Source Type: research

Tonic Pupil Following COVID-19
Abstract: A 37-year-old patient presented to our emergency department with sudden onset decreased vision with a history of being treated for COVID 19 3 weeks earlier. On examination, she was found to have a tonic right pupil, which was confirmed with a dilute pilocarpine test. As tonic pupils are known to be caused by neurotropic viruses and our current understanding of the SARS-CoV-2 is that it does affect the nervous system, we feel that the tonic pupil in our patient may be secondary to COVID 19. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Photo and Video Essay Source Type: research

Contained Rupture of a Posterior Communicating Artery Aneurysm in a Patient With a Third Nerve Palsy
We report one such example of a patient who developed new-onset severe headache and vomiting and did not seek medical attention because of COVID-19. Two months later, she was noted to have ptosis during a routine follow-up and was found to have a complete, pupil-involving third nerve palsy. Computed tomography angiography was performed and revealed an irregular bilobed saccular aneurysm (7 × 9 × 5 mm) of the right posterior communicating (PComm) artery, but no acute hemorrhage was visible on CT. On MRI, immediately adjacent to the aneurysm, there was a small subacute hematoma in the right medial temporal lobe w...
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Photo and Video Essay Source Type: research

Acute Complete Oculomotor Nerve Palsy in a Young Male Due to a Skull Base Myofibroma
Abstract: A 25-year-old male patient visited the ophthalmology clinic because of upper eye lid ptosis in the right eye, binocular double vision, and light sensitivity. He was diagnosed with a complete third nerve palsy caused by a skull base myofibroma, a rare clinical entity that has not been described before in oculomotor nerve palsy. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Photo and Video Essay Source Type: research

Characteristic Visual Field Defect From Lateral Geniculate Body Stroke
In this report, the anatomy, pathophysiology, clinical findings, and previously reported etiologies of lateral geniculate body lesions are reviewed. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Photo and Video Essay Source Type: research

Sinonasal Chondrosarcoma Presenting With Isolated Severe Vision Loss
Abstract: A 24-year-old man presented with a 2-month history of progressive, painless vision loss in the right eye, with no history of headache, nasal congestion, rhinorrhea, or epistaxis. His visual acuity was counting fingers at 1 ft in the right eye and 20 of 20 in the left eye with a right relative afferent pupillary defect and mild temporal optic disc pallor. MRI of the brain and orbits showed a mass involving bilateral ethmoid and sphenoid sinuses and right nasal cavity. He underwent urgent extended endoscopic endonasal transsphenoidal approach for resection of the sinonasal skull base tumor and photon radiation ...
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Photo and Video Essay Source Type: research

Bitemporal Hemianopia Secondary to Acute Zonal Occult Outer Retinopathy
Abstract: A 58-year-old man noticed shadows in the temporal visual field of each eye and photopsias within these scotomas for the past year. Formal visual fields demonstrated bitemporal hemianopia. MRI of the sella was normal, but fundus autofluorescence (FAF) demonstrated an area of hyperautofluorescence in the nasal retina of each eye corresponding to the loss of retinal pigment epithelium and photoreceptors. A diagnosis of acute zonal occult outer retinopathy was made based on the presence of trizonal involvement on FAF. This case is a reminder that bitemporal hemianopia can be caused by a retinopathy involving nasa...
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Photo and Video Essay Source Type: research

Dry Nonproductive Cough as the Presenting Symptom of Giant Cell Arteritis
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Delayed Onset of Mixed Cranial Neuropathies and Cluster Headache After Embolization of Indirect Carotid-Cavernous Fistula
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Slowly Progressive Ophthalmoplegia as a Presenting Symptom of Myotonic Dystrophy Type 1
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Third Nerve Palsy Due to Posterior Communicating Artery Aneurysm Rupture Into the Subdural Space
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Neuro-Ophthalmic Presentations of Common Carotid Artery Occlusion: A Case Series
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Anterior Ischemic Optic Neuropathy Secondary to Carotid Artery Dissection
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Reversal of Visual Loss From Skull Base Osteomyelitis in a Pediatric Patient
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

BRAF V600E-Mutated Ganglioglioma of the Optic Pathway: A Case Report and Review of the Literature
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Bilateral Optic Neuropathy Secondary to Toxicity From Tumor-Infiltrating Lymphocytes Therapy Combined With Checkpoint Blockade
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Food Aversion Leading to Nutritional Optic Neuropathy in a Child With Severe Vitamin A Deficiency
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Severe Leber Hereditary Optic Neuropathy Plus Disease in a Middle-Aged Man
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Optic Neuritis Associated With Tumor Necrosis Factor–Alpha Inhibitor Certolizumab
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Vitreopapillary Traction Masquerading as Papillitis and Papilledema
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Papilledema in a Patient With Intracranial Hypotension
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Severe Vision Loss and Intracranial Hypertension Presenting as Delayed Sequelae of “Mild” Carbon Monoxide Poisoning
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Isolated Asymmetric Progressive Optic Neuropathy as a First Presentation of Charcot–Marie–Tooth Disease Type 2A
No abstract available (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Clinical Correspondence Source Type: research

Publication Rate of Abstracts Presented at the North American Neuro-Ophthalmology Society Annual Meeting From 2008 to 2017
Conclusions: Publication rate of NANOS abstracts is comparable to other conferences in ophthalmology and the neurological sciences. Conference attendees should be aware that more than two-thirds of abstracts fail to be published and publication rates vary widely by type of submission. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

Involuntary “Voluntary” Nystagmus
Conclusions: The patterns seen in these patients suggest that there is a spectrum of oculomotor saccadic instabilities that includes voluntary nystagmus on one extreme and ocular flutter on the other. In between these 2 are both normal and abnormal patients with eye movements indistinguishable from ocular flutter/voluntary nystagmus that may or may not be induced by convergence. It is suggested that involuntary “voluntary nystagmus” is a real condition and that psychopathology should be ruled in rather than simply assumed. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

Antibody Development in Patients Treated Long-Term With OnabotulinumtoxinA for Benign Essential Blepharospasm and Hemifacial Spasm
Conclusions: The data support previous studies showing low incidence of antibody formation for botulinum A toxins with this subset of long-term treated patients. The results also provide further evidence for studies that have suggested increased onabotulinumtoxinA treatment volumes and/or decreased intervals between treatments are not due to neutralizing antibody formation and secondary non-response, but rather study designs that do not consider the titration phase of initial treatments. This study is specific to long-term treated patients, and the results cannot be generalized to patients naive to treatment. (Source: ...
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

Predictive Value of International Classification of Diseases Codes for Idiopathic Intracranial Hypertension in a University Health System
Conclusions: An ICD-9 or -10 code for IIH had a PPV of 63% for probable or definite IIH in patients with necessary diagnostic testing performed at a single institution. Coding accuracy was improved in patients with an IIH ICD code assigned by an ophthalmologist. Use of coding algorithms considering treatment providers, number of codes, and treatment is a potential strategy to reduce misclassification bias in medical claims–based research on IIH. However, these are associated with a reduced sample size. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

HINTS Examination in Acute Vestibular Neuritis: Do Not Look Too Hard for the Skew
Conclusion: Seven cases of typical AVN with an OTR are presented, and in the authors' experience, the presence of a subtle OTR is a common feature of AVN in these patients. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

Ocular Motor and Vestibular Characteristics of Antiglutamic Acid Decarboxylase–Associated Neurologic Disorders
Conclusions: Individuals with anti-GAD–associated neurologic disorders may present with prominent VOM abnormalities at the initial symptom onset that localize to the cerebellum and/or brainstem. In our cohort, immune and symptomatic therapies improved clinical outcomes and symptomatology. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

Eye Movements in Fragile X-Associated Tremor/Ataxia Syndrome
Conclusion: The results show that clinical examination findings of ocular abnormalities, using the ICARS oculomotor disorders movement subscale, are not more common in FXTAS or FMR1 premutation carriers than normal controls on examination in the clinic. Examining a larger cohort of patients with FXTAS would be an ideal next step. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

Resolved External Ophthalmoplegia and Hearing Loss in Wernicke's Encephalopathy With Thiamine Replacement
Conclusions: This case is an example of how awareness of the variations in the clinical presentation of WE can be crucial in achieving an early diagnosis and obtaining better outcomes. A history of the poor nutritional status can be an important clue to aid in this early diagnosis. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

Dorsal Midbrain Syndrome: Clinical and Imaging Features in 75 Cases
Conclusions: This large series expands on the clinical profile of DMS. Neoplasms and strokes were the most common causes. Obstructive hydrocephalus alone, identified as a major cause in the largest previously published series, was uncommon. At least 3 neuro-ophthalmic signs were present in nearly all patients, with upgaze deficit as predominant. Unlike an earlier report, this study found no correlation between brain imaging and clinical signs. Neuro-ophthalmic signs persisted even after neoplasms were successfully treated and improved only slightly after stroke. Telephone interviews with patients revealed that diplopia...
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

Delayed-Onset Cranial Nerve Palsy After Transvenous Embolization of Indirect Carotid Cavernous Fistulas
Conclusions: Delayed CNP can develop despite complete endovascular obliteration of the CCF. The cause of delayed CNP is not yet determined, but may represent fibrosis and ischemia. Long-term follow-up is needed even after complete neurological and radiological recovery is attained in the immediate perioperative period. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

Orbital Apex Syndrome Secondary to Invasive Aspergillus Infection: A Case Series and Literature Review
Conclusions: The present cases illustrate well the challenge in the diagnosis and treatment of OAS due to invasive sinus aspergillosis. Our review and analysis of 73 cases support the notion that a high index of suspicion leading to early biopsy with histology and fungal culture is paramount for diagnosis. Early empiric antifungal treatment and debridement can potentially reduce morbidity and mortality. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

The Usefulness of Anti-acetylcholine Receptor Binding Antibody Testing in Diagnosing Ocular Myasthenia Gravis
Conclusion: The study suggests the higher utility of the AChR binding Abs testing in diagnosing OMG due to its high sensitivity, specificity, and positive predictive value. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

Effect of Initial Prednisone Dosing on Ocular Myasthenia Gravis Control
Conclusion: Based on the results of this small retrospective study, it seems initial treatment for ocular myasthenia gravis with a mean maximum daily prednisone dose of 10 mg is similarly effective compared with mean maximum daily dose of 29 mg for control at 1 month. (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

Comitant Ocular Deviation in Myasthenia Gravis
Background: Occurrence of comitant ocular deviation in myasthenia gravis (MG) is not well described. Methods: A retrospective analysis of patients with ocular or generalized MG evaluated at a neuro-ophthalmology clinic for a 6-year period. Comitant ocular deviation was defined as magnitude of deviations in all planes varying by (Source: Journal of Neuro-Ophthalmology)
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research