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Total 393 results found since Jan 2013.

Influence of the three ‐dimensional culture of human bone marrow mesenchymal stromal cells within a macroporous polysaccharides scaffold on Pannexin 1 and Pannexin 3.
This study provides new insights on the expression of pannexins in HBMSCs on a 3D microenvironment during the osteogenic differentiation, in vitro and in vivo.
Source: Journal of Tissue Engineering and Regenerative Medicine - November 1, 2017 Category: Biotechnology Authors: Julien Guerrero, Hugo Oliveira, Rachida Aid, Reine Bareille, Robin Siadous, Didier Letourneur, Yong Mao, Joachim Kohn, Jo ëlle Amédée Tags: RESEARCH ARTICLE Source Type: research

In situ monitoring of PTHLH secretion in neuroblastoma cells cultured onto nanoporous membranes
Publication date: 1 June 2018 Source:Biosensors and Bioelectronics, Volume 107 Author(s): Alfredo de la Escosura-Muñiz, Marisol Espinoza-Castañeda, Alejandro Chamorro-García, Carlos J. Rodríguez-Hernández, Carmen de Torres, Arben Merkoçi In this work, we propose for the first time the use of anodic aluminum oxide (AAO) nanoporous membranes for in situ monitoring of parathyroid hormone-like hormone (PTHLH) secretion in cultured human cells. The biosensing system is based on the nanochannels blockage upon immunocomplex formation, which is electrically monitored through the voltammetric oxidation of Prussian blue nanop...
Source: Biosensors and Bioelectronics - February 11, 2018 Category: Biotechnology Source Type: research

BST2 promotes cell proliferation, migration and induces NF- κB activation in gastric cancer.
CONCLUSION: BST2 possesses the oncogenic potential in GC by regulating the proliferation, apoptosis, and migratory ability of GC cells, thereby BST2 could be a potential therapeutic target for the treatment of GC. PMID: 29774441 [PubMed - as supplied by publisher]
Source: Biotechnology Letters - May 17, 2018 Category: Biotechnology Authors: Liu W, Cao Y, Guan Y, Zheng C Tags: Biotechnol Lett Source Type: research

The combinational effect of E6/E7 siRNA and anti-miR-182 on apoptosis induction in HPV16-positive cervical cells
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Source: Artificial Cells, Blood Substitutes, and Biotechnology - June 6, 2018 Category: Biotechnology Authors: Hamidreza Javadi Abbas Sahebghadam Lotfi Saman Hosseinkhani Hossein Mehrani Jafar Amani Zahra Soheila Soheili Zahra Hojati Mehdi Kamali Source Type: research

Near-infrared light-activatable siRNA delivery by microcapsules for combined tumour therapy
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Source: Artificial Cells, Blood Substitutes, and Biotechnology - March 12, 2018 Category: Biotechnology Authors: Yalan Rui Bo Pang Jinnan Zhang Yuxi Liu Huixin Hu Zicun Liu Sarah Ama Baidoo Chang Liu Yu Zhao Siwen Li Source Type: research

Preparation of PEGylated cationic nanoliposome-siRNA complexes for cancer therapy
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Source: Artificial Cells, Blood Substitutes, and Biotechnology - February 24, 2018 Category: Biotechnology Authors: Fateme Haghiralsadat Ghasem Amoabediny Samira Naderinezhad Tymour Forouzanfar Marco N. Helder Behrouz Zandieh-Doulabi Source Type: research

Development and characterization of a novel cationic PEGylated niosome-encapsulated forms of doxorubicin, quercetin and siRNA for the treatment of cancer by using combination therapy
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Source: Artificial Cells, Blood Substitutes, and Biotechnology - July 23, 2018 Category: Biotechnology Authors: Mahdie Hemati Fateme Haghiralsadat Fatemeh Yazdian Farzaneh Jafari Ali Moradi Zahra Malekpour-Dehkordi Source Type: research

Dendrobium moniliforme stem extract inhibits lipoteichoic acid-induced inflammatory responses by upregulation of heme oxygenase-1.
In this study, we investigated anti-inflammatory effects of the aqueous extract of D. moniliforme stems (DM) in response to lipoteichoic acid (LTA), a major constituent of the cell wall of Gram-positive bacteria. DM inhibited LTA-induced expression of a pro-inflammatory mediator inducible nitric oxide synthase (iNOS) in the murine macrophages. And DM induced expression of heme oxygenase-1 (HO-1) at the transcriptional level. Conversely, the knockdown of HO-1 expression by siRNA markedly reversed the inhibitory effects of DM on LTA-induced iNOS expression. We also demonstrated that nuclear translocation of Nrf2 was increase...
Source: Journal of Microbiology and Biotechnology - July 31, 2018 Category: Biotechnology Authors: Lee YJ, Kim JH, Kim Y Tags: J Microbiol Biotechnol Source Type: research

Cyclic peptide-based nanostructures as efficient siRNA carriers
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Source: Artificial Cells, Blood Substitutes, and Biotechnology - October 12, 2018 Category: Biotechnology Authors: Bijayananda Panigrahi Rohit Kumar Singh Sourav Mishra Dindyal Mandal Source Type: research

GM-CSF Enhances Mobilization of Bone Marrow Mesenchymal Stem Cells via a CXCR4-Medicated Mechanism
Conclusion:These results suggest that GM-CSF is a useful tool for mobilizing BM MSCs into the PB.
Source: Tissue Engineering and Regenerative Medicine - November 15, 2018 Category: Biotechnology Source Type: research

The hierarchical micro-/nanotextured topographies promote the proliferation and angiogenesis-related genes expression in human umbilical vein endothelial cells by initiation of Hedgehog-Gli1 signaling.
This study may contribute to the modification of biomaterial surfaces for better tissue integration and clinical performance. PMID: 30453796 [PubMed - as supplied by publisher]
Source: Artificial Cells, Nanomedicine and Biotechnology - November 21, 2018 Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research

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