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Specialty: Biotechnology

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Total 393 results found since Jan 2013.

The impact of the codelivery of drug-siRNA by trimethyl chitosan nanoparticles on the efficacy of chemotherapy for metastatic breast cancer cell line (MDA-MB-231)
10.1080/21691401.2016.1185727Peyman Eivazy
Source: Artificial Cells, Blood Substitutes, and Biotechnology - May 17, 2016 Category: Biotechnology Authors: Peyman EivazyFatemeh AtyabiFarhad Jadidi-NiaraghLeili Aghebati MalekiAbolfazl MiahipourJalal AbdolalizadehMehdi Yousefi Source Type: research

Mechanisms of immune system activation in mammalians by small interfering RNA (siRNA)
10.3109/21691401.2015.1102738Behzad Mansoori
Source: Artificial Cells, Blood Substitutes, and Biotechnology - October 25, 2015 Category: Biotechnology Authors: Behzad MansooriAli MohammadiSolmaz Shir JangBehzad Baradaran Source Type: research

Polyelectrolyte complexes of hTERT siRNA and polyethyleneimine: Effect of degree of PEG grafting on biological and cellular activity
10.3109/21691401.2015.1064936Fatemeh Safari
Source: Artificial Cells, Blood Substitutes, and Biotechnology - July 31, 2015 Category: Biotechnology Authors: Fatemeh SafariAli M. TamaddonNosratollah ZarghamiS. AbolmaliAbolfazl Akbarzadeh Source Type: research

Expression, Regulation, and Functional Characterization of FST Gene in Porcine Granulosa Cells.
The objective of this study was to evaluate the expression of Follistatin (FST) in the ovary of Xiushui Hang and Duroc sows at weaning and estrus, the effect of FSH on transcript abundance of FST gene in granulosa cells and the role of FST gene in the weaning to estrus using siRNAs targeted to FST gene. In the present study, expression of the FST mRNA was evaluated by real time PCR. The FST mRNA levels showed a reduction from weaning to the estrus in both Xiushui Hang and Duroc sows, and the mRNA levels in Duroc ovary was higher than in Xiushui Hang sows at the beginning of estrus. Granulosa cells were obtained from the tw...
Source: Animal Biotechnology - August 29, 2016 Category: Biotechnology Authors: Zhou Q, Wan M, Wei Q, Song Q, Xiong L, Huo J, Huang J Tags: Anim Biotechnol Source Type: research

SiRNA-mediated silencing of Snail-1 induces apoptosis and alters micro RNA expression in human urinary bladder cancer cell line
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Source: Artificial Cells, Blood Substitutes, and Biotechnology - June 19, 2016 Category: Biotechnology Authors: Seyed Mohammad Hossein Musavi Shenas Behzad Mansoori Ali Mohammadi Shima Salehi Behzad Kaffash Behnaz Talebi Zohreh Babaloo Dariush Shanehbandi Behzad Baradaran Source Type: research

The impact of the codelivery of drug-siRNA by trimethyl chitosan nanoparticles on the efficacy of chemotherapy for metastatic breast cancer cell line (MDA-MB-231)
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Source: Artificial Cells, Blood Substitutes, and Biotechnology - May 17, 2016 Category: Biotechnology Authors: Peyman Eivazy Fatemeh Atyabi Farhad Jadidi-Niaragh Leili Aghebati Maleki Abolfazl Miahipour Jalal Abdolalizadeh Mehdi Yousefi Source Type: research

Co-delivery of insulin-like growth factor 1 receptor specific siRNA and doxorubicin using chitosan-based nanoparticles enhanced anticancer efficacy in A549 lung cancer cell line
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Source: Artificial Cells, Blood Substitutes, and Biotechnology - March 31, 2017 Category: Biotechnology Authors: Hajar Shali Mahdi Shabani Fatemeh Pourgholi Mahsa Hajivalili Leili Aghebati-Maleki Farhad Jadidi-Niaragh Behzad Baradaran Ali Akbar Movassaghpour Akbari Vahid Younesi Mehdi Yousefi Source Type: research

Lipid nanoparticle-based co-delivery of epirubicin and BCL-2 siRNA for enhanced intracellular drug release and reversing multidrug resistance
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Source: Artificial Cells, Blood Substitutes, and Biotechnology - April 10, 2017 Category: Biotechnology Authors: Miao Yu Shangcong Han Zhongai Kou Jialing Dai Jiao Liu Chen Wei Yitong Li Lutao Jiang Yong Sun Source Type: research

Advances in siRNA delivery in cancer therapy
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Source: Artificial Cells, Blood Substitutes, and Biotechnology - April 20, 2017 Category: Biotechnology Authors: Aishwarya Singh Piyush Trivedi Narendra Kumar Jain Source Type: research

Lipid nanoparticle-based co-delivery of epirubicin and BCL-2 siRNA for enhanced intracellular drug release and reversing multidrug resistance
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Source: Artificial Cells, Blood Substitutes, and Biotechnology - April 10, 2017 Category: Biotechnology Authors: Miao Yu Shangcong Han Zhongai Kou Jialing Dai Jiao Liu Chen Wei Yitong Li Lutao Jiang Yong Sun Source Type: research

Co-delivery of insulin-like growth factor 1 receptor specific siRNA and doxorubicin using chitosan-based nanoparticles enhanced anticancer efficacy in A549 lung cancer cell line
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Source: Artificial Cells, Blood Substitutes, and Biotechnology - March 31, 2017 Category: Biotechnology Authors: Hajar Shali Mahdi Shabani Fatemeh Pourgholi Mahsa Hajivalili Leili Aghebati-Maleki Farhad Jadidi-Niaragh Behzad Baradaran Ali Akbar Movassaghpour Akbari Vahid Younesi Mehdi Yousefi Source Type: research

The use of mechano growth factor to prevent cartilage degeneration in knee osteoarthritis
This study demonstrated that MGF treatment can inhibit the pathological apoptosis of OA chondrocytes and promote the proliferation, migration and matrix synthesis of the chondrocytes. The results also demonstrate that the degeneration of OA cartilage can be delayed by MGF treatment partially via PERK‐regulated UPR and suggest a potential therapeutic application of MGF for OA treatment. This article is protected by copyright. All rights reserved.
Source: Journal of Tissue Engineering and Regenerative Medicine - June 9, 2017 Category: Biotechnology Authors: Yang Song, Kang Xu, Can Yu, Lili Dong, Peixing Chen, Yonggang Lv, Martin Y.M. Chiang, Linhao Li, Wanqian Liu, Li Yang Tags: RESEARCH ARTICLE Source Type: research

MiR-338-3p inhibits TNF- α-induced lipogenesis in human sebocytes.
CONCLUSIONS: MiR-338-3p suppresses the TNF-α-induced lipogenesis in sebocytes by targeting PREX2a and down-regulating PI3K/AKT signaling. PMID: 28597147 [PubMed - as supplied by publisher]
Source: Biotechnology Letters - June 9, 2017 Category: Biotechnology Authors: Liu J, Cao L, Feng Y, Li Y, Li T Tags: Biotechnol Lett Source Type: research

Graded functionalization of biomaterial surfaces using mussel-inspired adhesive coating of polydopamine.
In this study, by controlling oxidative polymerization of dopamine, we demonstrated universal techniques for generating chemical gradients on various materials with adaptability for secondary molecule immobilization. Diffusion-controlled oxygen supply was successfully exploited for coating of polydopamine (PD) in a gradient manner on different materials, regardless of their surface chemistry, which resulted in gradient in hydrophilicity and surface roughness. The PD gradient controlled graded adhesion and spreading of human mesenchymal stem cells (hMSCs) and endothelial cells. Furthermore, the PD gradient on these surfaces...
Source: Colloids and Surfaces - August 19, 2017 Category: Biotechnology Authors: Perikamana SKM, Shin YM, Lee JK, Lee YB, Heo Y, Ahmad T, Park SY, Shin J, Park KM, Jung HS, Cho SW, Shin H Tags: Colloids Surf B Biointerfaces Source Type: research