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Specialty: Biotechnology
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Total 393 results found since Jan 2013.
Recent advances in siRNA delivery systems for prostate cancer therapy
Curr Pharm Biotechnol. 2021 Jun 15. doi: 10.2174/1389201022666210615123211. Online ahead of print.ABSTRACTThe critical problems of conventional prostate cancer therapeutic strategies like nonspecific toxicity and multi-drug resistance prompted the development and application of countless nanoparticle-based siRNA therapeutics. The main challenges to siRNA-based therapeutics becoming a new paradigm in the treatment of prostate cancer stem from the lack of safe and effective delivery systems, immune system stimulation, poor knowledge of nano-bio interactions, and limitations concerning designing, manufacturing, clinical trans...
Source: Current Pharmaceutical Biotechnology - June 16, 2021 Category: Biotechnology Authors: Shahin Aghamiri Pourya Raee Shiva Shahmohamadnejad Sasan Shabani Jaber Ghorbani Marzieh Sameni Mohammad Taha Ebrahimi Source Type: research
Co-delivery of STAT3 siRNA and methotrexate in breast cancer cells
This study is the first report on co-delivery of MTX and STAT3 siRNA by chitosan modified MSNs.PMID:35132929 | DOI:10.1080/21691401.2022.2030746
Source: Artificial Cells, Nanomedicine and Biotechnology - February 8, 2022 Category: Biotechnology Authors: Zahra Shakeran Jaleh Varshosaz Mehrnaz Keyhanfar Hossein Mohammad-Beigi Karim Rahimi Duncan S Sutherland Source Type: research
Multifunctional magnetic nanocarriers for delivery of siRNA and shRNA plasmid to mammalian cells: Characterization, adsorption and release behaviors
This study introduces a new MNP functionalization that can be used for the magnetically driven intracellular delivery of nucleic acids.PMID:36162177 | DOI:10.1016/j.colsurfb.2022.112861
Source: Colloids and Surfaces - September 26, 2022 Category: Biotechnology Authors: Chi-Hsien Liu Cheng-Han Lin Yi-Jun Chen Wei-Chi Wu Chun-Chao Wang Source Type: research
