The use of mechano growth factor to prevent cartilage degeneration in knee osteoarthritis

This study demonstrated that MGF treatment can inhibit the pathological apoptosis of OA chondrocytes and promote the proliferation, migration and matrix synthesis of the chondrocytes. The results also demonstrate that the degeneration of OA cartilage can be delayed by MGF treatment partially via PERK‐regulated UPR and suggest a potential therapeutic application of MGF for OA treatment. This article is protected by copyright. All rights reserved.
Source: Journal of Tissue Engineering and Regenerative Medicine - Category: Biotechnology Authors: Tags: RESEARCH ARTICLE Source Type: research