The use of mechano growth factor to prevent cartilage degeneration in knee osteoarthritis
This study demonstrated that MGF treatment can inhibit the pathological apoptosis of OA chondrocytes and promote the proliferation, migration and matrix synthesis of the chondrocytes. The results also demonstrate that the degeneration of OA cartilage can be delayed by MGF treatment partially via PERK‐regulated UPR and suggest a potential therapeutic application of MGF for OA treatment. This article is protected by copyright. All rights reserved.
Source: Journal of Tissue Engineering and Regenerative Medicine - Category: Biotechnology Authors: Yang Song, Kang Xu, Can Yu, Lili Dong, Peixing Chen, Yonggang Lv, Martin Y.M. Chiang, Linhao Li, Wanqian Liu, Li Yang Tags: RESEARCH ARTICLE Source Type: research