Global vaccine coverage and childhood survival estimates: 1990-2019
CONCLUSION: Vaccines continue to reduce childhood mortality significantly, especially in Gavi-supported countries, emphasizing the need for increased investment in routine immunization programmes.PMID:38562199 | PMC:PMC10976869 | DOI:10.2471/BLT.23.290129 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Haijun Zhang Bryan Patenaude Haonan Zhang Mark Jit Hai Fang Source Type: research

Global vaccine coverage and childhood survival estimates: 1990-2019
CONCLUSION: Vaccines continue to reduce childhood mortality significantly, especially in Gavi-supported countries, emphasizing the need for increased investment in routine immunization programmes.PMID:38562199 | PMC:PMC10976869 | DOI:10.2471/BLT.23.290129 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Haijun Zhang Bryan Patenaude Haonan Zhang Mark Jit Hai Fang Source Type: research

Global vaccine coverage and childhood survival estimates: 1990-2019
CONCLUSION: Vaccines continue to reduce childhood mortality significantly, especially in Gavi-supported countries, emphasizing the need for increased investment in routine immunization programmes.PMID:38562199 | PMC:PMC10976869 | DOI:10.2471/BLT.23.290129 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Haijun Zhang Bryan Patenaude Haonan Zhang Mark Jit Hai Fang Source Type: research

Global vaccine coverage and childhood survival estimates: 1990-2019
CONCLUSION: Vaccines continue to reduce childhood mortality significantly, especially in Gavi-supported countries, emphasizing the need for increased investment in routine immunization programmes.PMID:38562199 | PMC:PMC10976869 | DOI:10.2471/BLT.23.290129 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Haijun Zhang Bryan Patenaude Haonan Zhang Mark Jit Hai Fang Source Type: research

Global vaccine coverage and childhood survival estimates: 1990-2019
CONCLUSION: Vaccines continue to reduce childhood mortality significantly, especially in Gavi-supported countries, emphasizing the need for increased investment in routine immunization programmes.PMID:38562199 | PMC:PMC10976869 | DOI:10.2471/BLT.23.290129 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Haijun Zhang Bryan Patenaude Haonan Zhang Mark Jit Hai Fang Source Type: research

Development and application of one-step multiplex Real-Time PCR for detection of three main pathogens associated with bovine neonatal diarrhea
In this study, we developed a one-step multiplex Real-Time PCR assay to simultaneously detect BRV, BCoV, and E. coli K99+. The assay performance on field samples was evaluated on 1100 rectal swabs of diseased cattle with diarrhea symptoms and compared with the conventional gel-based RT-PCR assay detect BRV, BCoV, and E. coli K99+.ResultsThe established assay could specifically detect the target pathogens without cross-reactivity with other pathogens. A single real-time PCR can detect ~1 copy/µL for each pathogen, and multiplex real-time PCR has a detection limit of 10 copies/µL. Reproducibility as measured by standard de...
Source: Frontiers in cellular and infection microbiology - April 2, 2024 Category: Microbiology Source Type: research

Human Cytomegalovirus Seropositivity and Its Influence on Oral Rotavirus Vaccine Immunogenicity: A Specific Concern for HIV-Exposed-Uninfected Infants
This study highlights the complexity of immunological responses and the need for targeted interventions to ensure oral rotavirus vaccine efficacy, especially in vulnerable subpopulations.PMID:38546123 | DOI:10.1093/cei/uxae029 (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - March 28, 2024 Category: Allergy & Immunology Authors: Natasha Laban Samuel Bosomprah Roma Chilengi Michelo Simuyandi Caroline Chisenga Harriet Ng'ombe Kalo Musukuma-Chifulo Martin Goodier Source Type: research

Human Cytomegalovirus Seropositivity and Its Influence on Oral Rotavirus Vaccine Immunogenicity: A Specific Concern for HIV-Exposed-Uninfected Infants
This study highlights the complexity of immunological responses and the need for targeted interventions to ensure oral rotavirus vaccine efficacy, especially in vulnerable subpopulations.PMID:38546123 | DOI:10.1093/cei/uxae029 (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - March 28, 2024 Category: Allergy & Immunology Authors: Natasha Laban Samuel Bosomprah Roma Chilengi Michelo Simuyandi Caroline Chisenga Harriet Ng'ombe Kalo Musukuma-Chifulo Martin Goodier Source Type: research

Evaluation of Mastadenovirus and Rotavirus Presence in Phyllostomid, Vespertilionid, and Molossid Bats Captured in Rio Grande do Sul, Southern Brazil
Food Environ Virol. 2024 Mar 26. doi: 10.1007/s12560-023-09575-y. Online ahead of print.ABSTRACTBat-borne viruses may affect public health and the global economy. These mammals have a wide geographical distribution and unique biological, physiological, and immunogenic characteristics, allowing the dissemination of many known and unknown viruses. Enteric viruses, such as adeno (AdV) and rotaviruses, are recognized as the main causative agents of disease and outbreaks. In the present study, the presence of viruses from Adenoviridae and Reoviridae families was evaluated in molossid, phyllostomid, and vespertilionid bats captu...
Source: Adv Data - March 27, 2024 Category: Epidemiology Authors: Alexandre Sita Gabriela Esp índola Birlem Deivid de Souza da Silva Gabriela Mattos Possamai Karla Petry Paula Rodrigues de Almeida Larissa Mallmann Jana ína Franciele Stein Meriane Demoliner Juliana Schons Gularte Alana Witt Hansen Andr é Alberto Witt Source Type: research

Evaluation of Mastadenovirus and Rotavirus Presence in Phyllostomid, Vespertilionid, and Molossid Bats Captured in Rio Grande do Sul, Southern Brazil
AbstractBat-borne viruses may affect public health and the global economy. These mammals have a wide geographical distribution and unique biological, physiological, and immunogenic characteristics, allowing the dissemination of many known and unknown viruses. Enteric viruses, such as adeno (AdV) and rotaviruses, are recognized as the main causative agents of disease and outbreaks. In the present study, the presence of viruses fromAdenoviridae andReoviridae families was evaluated in molossid, phyllostomid, and vespertilionid bats captured in Rio Grande do Sul, Southern Brazil, between September 2021 and July 2022. Sixty bat...
Source: Food and Environmental Virology - March 26, 2024 Category: Virology Source Type: research

The first confirmed cases of pigeon rotavirus A (RVA) infection in domestic pigeons < em > (Columba livia) < /em > in Poland
CONCLUSION: Pigeon-type RVA is also a cause of YPD in Poland and is a serious challenge for racing pigeon breeders and veterinarians, especially during the training and flights of young pigeons.PMID:38525231 | PMC:PMC10960255 | DOI:10.2478/jvetres-2024-0006 (Source: Cell Research)
Source: Cell Research - March 25, 2024 Category: Cytology Authors: Krzysztof Adamczyk Dennis Rubbenstroth Aleksandra Ledwo ń Rafa ł Sapierzyński Piotr Szeleszczuk Source Type: research

An isothermal nucleic acid amplification-based enzymatic recombinase amplification method for dual detection of porcine epidemic diarrhea virus and porcine rotavirus A
In this study, a dual ERA method to detect and distinguish between PEDV and PoRVA nucleic acids was established. The method shows high sensitivity, as the detection limits were 101 copies/μL for both viruses. To test the usefulness of this method in clinical settings, we tested 64 swine clinical samples. Our results were 100% matched with those acquired using a commercially available kit. Therefore, we have successfully developed a dual diagnostic ERA nucleic acids method for detecting and distinguishing between PEDV and PoRVA.PMID:38522136 | DOI:10.1016/j.virol.2024.110062 (Source: Virology)
Source: Virology - March 24, 2024 Category: Virology Authors: Qianwen Wu Xing Liu Jingyu Wang Sijia Xu Fanliang Zeng Ling Chen Guihong Zhang Heng Wang Source Type: research

An isothermal nucleic acid amplification-based enzymatic recombinase amplification method for dual detection of porcine epidemic diarrhea virus and porcine rotavirus A
In this study, a dual ERA method to detect and distinguish between PEDV and PoRVA nucleic acids was established. The method shows high sensitivity, as the detection limits were 101 copies/μL for both viruses. To test the usefulness of this method in clinical settings, we tested 64 swine clinical samples. Our results were 100% matched with those acquired using a commercially available kit. Therefore, we have successfully developed a dual diagnostic ERA nucleic acids method for detecting and distinguishing between PEDV and PoRVA.PMID:38522136 | DOI:10.1016/j.virol.2024.110062 (Source: Virology)
Source: Virology - March 24, 2024 Category: Virology Authors: Qianwen Wu Xing Liu Jingyu Wang Sijia Xu Fanliang Zeng Ling Chen Guihong Zhang Heng Wang Source Type: research

Human intestinal enteroids platform to assess the infectivity of gastroenteritis viruses in wastewater
This study primarily aimed to test the feasibility of the human intestinal enteroids (HIE) model to demonstrate the infectivity of multiple gastroenteritis viruses in wastewater. Initially, key factors affecting viral replication in HIE model were assessed, and results demonstrated that the reagent-assisted disruption of 3D HIE represents an efficient alternative to syringe pass-through, and the filtering of HuNoV stool suspensions could be avoided. Moreover, comparable replication yields of clinical strains of HuNoV genogroup I (GI), HuNoV GII, rotavirus (RV), astrovirus (HAstV), and adenoviruses (HAdV) were obtained in s...
Source: Cell Research - March 23, 2024 Category: Cytology Authors: Noelia Carmona-Vicente Annamaria Pandiscia Cristina Santiso-Bell ón Alba Perez-Catalu ña Jes ús Rodríguez-Díaz Veronica P Costantini Javier Buesa Jan Vinj é Gloria S ánchez Walter Randazzo Source Type: research

A phase 3 randomized, open-label study evaluating the immunogenicity and safety of concomitant and staggered administration of a live, pentavalent rotavirus vaccine and an inactivated poliomyelitis vaccine in healthy infants in China
Volume 20, Issue 1, December 2024 . (Source: Human Vaccines and Immunotherapeutics)
Source: Human Vaccines and Immunotherapeutics - March 21, 2024 Category: Allergy & Immunology Authors: Shaomin ChenZhifang YingYan LiuYuan LiYebin YuMeilian HuangZhuhang HuangZhiqiang OuYuyi LiaoYong ZhangGuixiu LiuWeiwei ZhaoRong FuQiong ShouMinghuan ZhengXueyan LiaoYingmei TuJon StekJonathan HartzelChanggui LiJikai Zhanga Biological Products Surveillance Source Type: research