Effectiveness of self-financed rotavirus vaccines on acute gastroenteritis primary care episodes using real-world data in Spain: a propensity score –matched analysis of cohort study
Conclusion: Considering that RV is the causative agent in 20% of AGE cases, a direct effectiveness of 82% preventing AGE-PC episodes due to RV could be deduced using a novel spatiotemporal approach. A reduction of 17% of AGE-PC episodes in unvaccinated was observed in areas with VC over 70% because of indirect protection.What is Known:• The effectiveness of RV vaccines preventing hospitalizations due to RV-acute gastroenteritis (RV-AGE) has been extensively studied. However, RV also burdens the primary care (PC) setting, and data on vaccine effectiveness (VE) in preventing AGE-PC visits are scarce.• The RV vaccine dis...
Source: European Journal of Pediatrics - April 7, 2024 Category: Pediatrics Source Type: research
Viruses, Vol. 16, Pages 565: VP4 Mutation Boosts Replication of Recombinant Human/Simian Rotavirus in Cell Culture
enhagen
Rotavirus A (RVA) is the leading cause of diarrhea requiring hospitalization in children and causes over 100,000 annual deaths in Sub-Saharan Africa. In order to generate next-generation vaccines against African RVA genotypes, a reverse genetics system based on a simian rotavirus strain was utilized here to exchange the antigenic capsid proteins VP4, VP7 and VP6 with those of African human rotavirus field strains. One VP4/VP7/VP6 (genotypes G9-P[6]-I2) triple-reassortant was successfully rescued, but it replicated poorly in the first cell culture passages. However, the viral titer was enhanced upon further pass...
Source: Viruses - April 5, 2024 Category: Virology Authors: Roman Valusenko-Mehrkens Katja Schilling-Loeffler Reimar Johne Alexander Falkenhagen Tags: Article Source Type: research
Rotavirus vaccine dose-two dropout and its associated factors among children who received rotavirus vaccine dose-one in Sub-Saharan African countries: A multilevel analysis of the recent demographic and health survey
Volume 20, Issue 1, December 2024 . (Source: Human Vaccines and Immunotherapeutics)
Source: Human Vaccines and Immunotherapeutics - April 5, 2024 Category: Allergy & Immunology Authors: Belayneh Shetie WorknehEnyew Getaneh MekonenAlebachew Ferede ZegeyeAlmaz Tefera GoneteTewodros Getaneh AlemuTadesse Tarik TamirBerhan TekebaMulugeta WassieAlemneh Tadesse KassieMohammed Seid Alia Department of Emergency and Critical Care Nursing, School o Source Type: research
Impact of Limosilactobacillus fermentum probiotic treatment on gut microbiota composition in sahiwal calves with rotavirus diarrhea: A 16S metagenomic analysis study ”
Diarrhea poses a major threat to bovine calves leading to mortality and economic losses. Among the causes of calf diarrhea, bovine rotavirus is a major etiological agent and may result in dysbiosis of gut micr... (Source: BMC Microbiology)
Source: BMC Microbiology - April 4, 2024 Category: Microbiology Authors: Nadeem Murtaza, Muhammad Nawaz, Tahir Yaqub and Asim Khalid Mehmood Tags: Research Source Type: research
Global vaccine coverage and childhood survival estimates: 1990-2019
CONCLUSION: Vaccines continue to reduce childhood mortality significantly, especially in Gavi-supported countries, emphasizing the need for increased investment in routine immunization programmes.PMID:38562199 | PMC:PMC10976869 | DOI:10.2471/BLT.23.290129 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Haijun Zhang Bryan Patenaude Haonan Zhang Mark Jit Hai Fang Source Type: research
Global vaccine coverage and childhood survival estimates: 1990-2019
CONCLUSION: Vaccines continue to reduce childhood mortality significantly, especially in Gavi-supported countries, emphasizing the need for increased investment in routine immunization programmes.PMID:38562199 | PMC:PMC10976869 | DOI:10.2471/BLT.23.290129 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Haijun Zhang Bryan Patenaude Haonan Zhang Mark Jit Hai Fang Source Type: research
Global vaccine coverage and childhood survival estimates: 1990-2019
CONCLUSION: Vaccines continue to reduce childhood mortality significantly, especially in Gavi-supported countries, emphasizing the need for increased investment in routine immunization programmes.PMID:38562199 | PMC:PMC10976869 | DOI:10.2471/BLT.23.290129 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Haijun Zhang Bryan Patenaude Haonan Zhang Mark Jit Hai Fang Source Type: research
Global vaccine coverage and childhood survival estimates: 1990-2019
CONCLUSION: Vaccines continue to reduce childhood mortality significantly, especially in Gavi-supported countries, emphasizing the need for increased investment in routine immunization programmes.PMID:38562199 | PMC:PMC10976869 | DOI:10.2471/BLT.23.290129 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Haijun Zhang Bryan Patenaude Haonan Zhang Mark Jit Hai Fang Source Type: research
Global vaccine coverage and childhood survival estimates: 1990-2019
CONCLUSION: Vaccines continue to reduce childhood mortality significantly, especially in Gavi-supported countries, emphasizing the need for increased investment in routine immunization programmes.PMID:38562199 | PMC:PMC10976869 | DOI:10.2471/BLT.23.290129 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Haijun Zhang Bryan Patenaude Haonan Zhang Mark Jit Hai Fang Source Type: research
Global vaccine coverage and childhood survival estimates: 1990-2019
CONCLUSION: Vaccines continue to reduce childhood mortality significantly, especially in Gavi-supported countries, emphasizing the need for increased investment in routine immunization programmes.PMID:38562199 | PMC:PMC10976869 | DOI:10.2471/BLT.23.290129 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Haijun Zhang Bryan Patenaude Haonan Zhang Mark Jit Hai Fang Source Type: research
Global vaccine coverage and childhood survival estimates: 1990-2019
CONCLUSION: Vaccines continue to reduce childhood mortality significantly, especially in Gavi-supported countries, emphasizing the need for increased investment in routine immunization programmes.PMID:38562199 | PMC:PMC10976869 | DOI:10.2471/BLT.23.290129 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Haijun Zhang Bryan Patenaude Haonan Zhang Mark Jit Hai Fang Source Type: research
Global vaccine coverage and childhood survival estimates: 1990-2019
CONCLUSION: Vaccines continue to reduce childhood mortality significantly, especially in Gavi-supported countries, emphasizing the need for increased investment in routine immunization programmes.PMID:38562199 | PMC:PMC10976869 | DOI:10.2471/BLT.23.290129 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Haijun Zhang Bryan Patenaude Haonan Zhang Mark Jit Hai Fang Source Type: research
Global vaccine coverage and childhood survival estimates: 1990-2019
CONCLUSION: Vaccines continue to reduce childhood mortality significantly, especially in Gavi-supported countries, emphasizing the need for increased investment in routine immunization programmes.PMID:38562199 | PMC:PMC10976869 | DOI:10.2471/BLT.23.290129 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Haijun Zhang Bryan Patenaude Haonan Zhang Mark Jit Hai Fang Source Type: research
Global vaccine coverage and childhood survival estimates: 1990-2019
CONCLUSION: Vaccines continue to reduce childhood mortality significantly, especially in Gavi-supported countries, emphasizing the need for increased investment in routine immunization programmes.PMID:38562199 | PMC:PMC10976869 | DOI:10.2471/BLT.23.290129 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Haijun Zhang Bryan Patenaude Haonan Zhang Mark Jit Hai Fang Source Type: research
Global vaccine coverage and childhood survival estimates: 1990-2019
CONCLUSION: Vaccines continue to reduce childhood mortality significantly, especially in Gavi-supported countries, emphasizing the need for increased investment in routine immunization programmes.PMID:38562199 | PMC:PMC10976869 | DOI:10.2471/BLT.23.290129 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Haijun Zhang Bryan Patenaude Haonan Zhang Mark Jit Hai Fang Source Type: research
