Epidemiological monitoring and genetic variation analysis of pathogens associated with porcine viral diarrhea in southern China from 2021 to 2023
In this study, we found SADS-CoV only in piglet diarrhea samples from Jiangxi, Guangdong, and Guangxi provinces in China, with a prevalence rate of 5.16% (11/213) in pig farms. Co-infection with these diarrhea-associated viruses is a common occurrence. The most common co-infections were PEDV and PoRV, with a prevalence rate of 6.64% (119/1,791), followed by PDCoV and PoRV, with a prevalence rate of 4.19% (75/1,791). Phylogenetic analyses showed that PEDV and PEDV variants prevalent in southern China during the past three years clustered into genotype GIIb and recombinant PEDV subtypes. Among the currently endemic PEDV, the...
Source: Frontiers in Microbiology - March 20, 2024 Category: Microbiology Source Type: research

Viruses, Vol. 16, Pages 453: Recent Molecular Characterization of Porcine Rotaviruses Detected in China and Their Phylogenetic Relationships with Human Rotaviruses
ang Xiaowen Li Bin Zhou Porcine rotavirus A (PoRVA) is an enteric pathogen capable of causing severe diarrhea in suckling piglets. Investigating the prevalence and molecular characteristics of PoRVA in the world, including China, is of significance for disease prevention. In 2022, a total of 25,768 samples were collected from 230 farms across China, undergoing porcine RVA positivity testing. The results showed that 86.52% of the pig farms tested positive for porcine RVA, with an overall positive rate of 51.15%. Through the genetic evolution analysis of VP7, VP4 and VP6 genes, it was revealed that G9 is the predomin...
Source: Viruses - March 14, 2024 Category: Virology Authors: Mengli Qiao Meizhen Li Yang Li Zewei Wang Zhiqiang Hu Jie Qing Jiapei Huang Junping Jiang Yaqin Jiang Jinyong Zhang Chunliu Gao Chen Yang Xiaowen Li Bin Zhou Tags: Article Source Type: research

Advancing the National Immunization Program in an era of achieving universal vaccine coverage in China and beyond
CONCLUSION: The articles emphasize the need for government leadership, strategic policymaking, and public awareness to enhance vaccine coverage and equity. The VaxLab will continue strengthening China's NIP by focusing on vaccine financing, emphasizing diversity, equity, and inclusion, and improving maternal vaccination coverage. Research will extend to Southeast Asian and Western Pacific regions, especially in middle-income countries facing challenges in vaccine financing and delivery. The collective efforts outlined in this collection show a commitment to evolving and adapting immunization strategies to meet global healt...
Source: Cancer Control - March 13, 2024 Category: Cancer & Oncology Authors: Shu Chen Lance E Rodewald Anna Heng Du Shenglan Tang Source Type: research

Advancing the National Immunization Program in an era of achieving universal vaccine coverage in China and beyond
ConclusionThe articles emphasize the need for government leadership, strategic policymaking, and public awareness to enhance vaccine coverage and equity. The VaxLab will continue strengthening China ’s NIP by focusing on vaccine financing, emphasizing diversity, equity, and inclusion, and improving maternal vaccination coverage. Research will extend to Southeast Asian and Western Pacific regions, especially in middle-income countries facing challenges in vaccine financing and delivery. The co llective efforts outlined in this collection show a commitment to evolving and adapting immunization strategies to meet global hea...
Source: Infectious Diseases of Poverty - March 13, 2024 Category: Infectious Diseases Source Type: research

Changes in vaccine coverage and incidence of acute gastroenteritis and severe rotavirus gastroenteritis in children < 5 years in Shibata City, Niigata Prefecture, Japan
Volume 20, Issue 1, December 2024 . (Source: Human Vaccines and Immunotherapeutics)
Source: Human Vaccines and Immunotherapeutics - March 13, 2024 Category: Allergy & Immunology Authors: Tomohiro OishiSatoshi HasegawaTokushi NakanoShoji SudoHiroaki KuwajimaShuko TokurikiTsutomu Tamuraa Department of Clinical Infectious Diseases, Kawasaki Medical School, Kurashiki, Okayama, Japanb Pediatric Department, Niigata Prefectural Shibata Hospital, Source Type: research

Viruses, Vol. 16, Pages 438: Novel Universal Recombinant Rotavirus a Vaccine Candidate: Evaluation of Immunological Properties
tin Olga V. Karpova Rotavirus infection is a leading cause of severe dehydrating gastroenteritis in children under 5 years of age. Although rotavirus-associated mortality has decreased considerably because of the introduction of the worldwide rotavirus vaccination, the global burden of rotavirus-associated gastroenteritis remains high. Current vaccines have a number of disadvantages; therefore, there is a need for innovative approaches in rotavirus vaccine development. In the current study, a universal recombinant rotavirus antigen (URRA) for a novel recombinant vaccine candidate against rotavirus A was obtained and ...
Source: Viruses - March 12, 2024 Category: Virology Authors: Dmitriy L. Granovskiy Nelli S. Khudainazarova Ekaterina A. Evtushenko Ekaterina M. Ryabchevskaya Olga A. Kondakova Marina V. Arkhipenko Marina V. Kovrizhko Elena P. Kolpakova Tatyana I. Tverdokhlebova Nikolai A. Nikitin Olga V. Karpova Tags: Article Source Type: research

Prevalence of Rotavirus antigen in children with gastroenteritis in Auchi Etsako West Local Government Area, Edo State, Nigeria
CONCLUSIONS: The study emphasizes the importance of rotavirus vaccination, promoting good hygiene practices, and raising awareness among parents, caregivers, and healthcare professionals. Further investigation is needed to explore additional risk factors and improve understanding of rotavirus infection in this population.PMID:38456028 | PMC:PMC10917567 | DOI:10.53854/liim-3201-9 (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - March 8, 2024 Category: Infectious Diseases Authors: Pius Omoruyi Omosigho Ugiagbe Victory Osayekewmen Guobadia Precious Oghogho Olalekan John Okesanya Janet Mosunmola Oladejo Uyigue Paulinus Osarodion Source Type: research