Psychological impact and associated factors of the COVID-19 pandemic among pregnant women in Fafan Zone health institutions, Somali Region, Eastern Ethiopia, 2021
Despite pregnant women's vulnerability to respiratory illnesses and pregnancy complications during the COVID-19 pandemic, research on its psychological impact in the study area, is limited. (Source: BMC Women's Health)
Source: BMC Women's Health - April 30, 2024 Category: OBGYN Authors: Meka Kedir Jibril, Ahmed Adem Yimam, Neima Ridwan Abdu and Seid Yimam Ali Tags: Research Source Type: research

Targeting strategies of antenatal balanced energy and protein supplementation in Addis Ababa, Ethiopia: study protocol for a randomized effectiveness study
Antenatal balanced energy and protein (BEP) supplements have well-documented benefits for pregnancy outcomes. However, considerable practical gaps remain in the effective and cost-effective delivery of antenat... (Source: Trials)
Source: Trials - April 30, 2024 Category: General Medicine Authors: Dongqing Wang, Tigest Shifraw, Janaina Calu Costa, Semira Abdelmenan, Sitota Tsegaye, Yoseph Berhane, Hanna Gulema, Hanna Berhane, Nebiyou Fasil, Firehiwot Workneh, Workagegnhu Tarekegn, Molin Wang, Nicolas A. Menzies, Alemayehu Worku, Yemane Berhane and Tags: Study protocol Source Type: research

How severity and classification of pulmonary hypertension affect pregnancy outcomes: a systematic review and timeline
Current consensus guidelines recommend that pregnancy is contraindicated in patients with pulmonary hypertension (PH) due to high maternal and fetal morbidity and mortality.1 In this systematic review we evaluated the data behind these recommendations to determine if all forms and severity of PH should be considered an absolute contraindication to pregnancy. Pulmonary hypertension is a complex disease involving multiple etiologies2 which increase pulmonary blood pressure. It is classified by the WHO (World Health Organization) according to the underlying pathology into five groups: 1. (Source: International Journal of Obstetric Anesthesia)
Source: International Journal of Obstetric Anesthesia - April 30, 2024 Category: Anesthesiology Authors: N.C. Cruz, E. Pham, H. Ali, J Nanavati, D Steppan, TM Kolb, AJ Thomas, J Murphy, S Nyhan, MC Grant, J Steppan Tags: Review Article Source Type: research

Life skills and reproductive health empowerment intervention for newly married women and their families to reduce unintended pregnancy in India: protocol for the TARANG cluster randomised controlled trial
Introduction In South Asia, younger women have high rates of unmet need for family planning and low empowerment. Life skills interventions can equip young women with agency, but the effectiveness of these interventions in reproductive and sexual autonomy and contraception has not been examined. Methods and analysis A two-arm, parallel, cluster randomised controlled trial will evaluate the impact of TARANG (Transforming Actions for Reaching and Nurturing Gender Equity and Empowerment), a life skills and reproductive health empowerment group-based intervention for newly married women, compared with usual services in the com...
Source: BMJ Open - April 30, 2024 Category: General Medicine Authors: Diamond-Smith, N., Gopalakrishnan, L., Leslie, H., Katz, E., Harper, C., Weiser, S., Patil, S. R. Tags: Open access, Global health Source Type: research

Pregnancy outcomes before and during COVID-19 pandemic in Tamale Metropolis, Ghana: A retrospective cohort study
This study assessed pregnancy outcomes before and during COVID-19 pandemic in Tamale Metropolis, Ghana. Methods/DesignA retrospective cohort study design was employed. A random sampling technique was used to select 450 women who delivered before or during the COVID-19 pandemic in Tamale Metropolis, Ghana. The respondents were interviewed using structured questionnaire at their homes. In this study, the data collected were socio-demographics characteristics, ANC attendance, before or during pandemic delivery, place of delivery and birth outcomes. Chi-square test and bivariate logistic regression analyses were performed unde...
Source: PLoS One - April 30, 2024 Category: Biomedical Science Authors: Obed Duah Kwaku Asumadu Source Type: research

The Diagnostic Yield of Chromosomal Microarray Analysis in Third-Trimester Fetal Abnormalities
Conclusion The 6.2% detection rate of significant CNVs in late-onset fetal anomalies confirms the value of CMA in third-trimester amniocentesis. The findings underscore the necessity of CMA for detecting CNVs potentially overlooked by NIPT and emphasize the importance of thorough genetic counseling. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - April 30, 2024 Category: Perinatology & Neonatology Authors: Elron, Eyal Maya, Idit Shefer-Averbuch, Noa Kahana, Sarit Matar, Reut Klein, Kochav Agmon-Fishman, Ifat Gurevitch, Merav Basel-Salmon, Lina Levy, Michal Tags: Original Article Source Type: research

EUROPEAN ASSOCIATION OF PERINATAL MEDICINE (EAPM) Position statement: Screening, diagnosis and management of congenital anomalies of the umbilical cord
Congenital anomalies of the umbilical cord are associated with an increased risk of pregnancy and perinatal complications. Some anomalies of the cord have a higher prevalence than other fetal structural anomalies. The most common anomalies are the absence of an umbilical artery and velamentous insertion of the cord (with or without vasa previa). These anomalies, even when not associated with fetal structural defects, increase the risk of adverse perinatal outcome including, fetal growth restriction and stillbirth. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 30, 2024 Category: OBGYN Authors: Eric Jauniaux, Cathrine Ebbing, Yinka Oyelese, Rony Maymon, Federico Prefumo, Amar Bhide Tags: Expert Opinion Source Type: research

Reducing Severe Maternal Morbidity for Birthing Persons with Severe Hypertension through a Statewide Quality Improvement Initiative
Hypertensive disorders of pregnancy are a leading preventable cause of severe maternal morbidity and maternal mortality worldwide. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - April 30, 2024 Category: OBGYN Authors: Ann BORDERS, Lauren KEENAN-DEVLIN, Elissa H. OH, Danielle YOUNG, William GROBMAN, Patricia LEE KING Tags: Original Research: Obstetrics Source Type: research

Covid-19 vaccination during pregnancy is not associated with an increased risk of severe post-partum hemorrhage
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - April 30, 2024 Category: OBGYN Authors: Maria C. Magnus, Trine Damsted Rasmussen, Anne K. Örtqvist, Laura L. Oakley, Stine Kjaer Urhoj, Olof Stephansson, Siri E. Håberg Tags: Research Letter Source Type: research

Blood pressure cut-offs at 11-13 weeks ’ gestation and risk of preeclampsia
A parallel has been drawn between first trimester placental vascular maturation and maternal cardiovascular adaptations, including blood pressure. Although 140/90 mmHg is well-accepted as the threshold for chronic hypertension in the general obstetric population in early pregnancy, a different threshold could apply to stratify risk of adverse outcomes, such as preeclampsia. This could have implications for interventions, such as the threshold for initiation of antihypertensive therapy and the target blood pressure level. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - April 30, 2024 Category: OBGYN Authors: Laura J. SLADE, Argyro SYNGELAKI, Milly WILSON, Hiten D. MISTRY, Ranjit AKOLEKAR, Peter VON DADELSZEN, Kypros H. NICOLAIDES, Laura A. MAGEE Tags: Original Research: Obstetrics Source Type: research

Southern African HIV Clinicians Society Guideline for the clinical management of syphilis
Syphilis, ‘the great imitator’, caused byTreponema pallidum infection, remains a complex and multifaceted disease with a rich history of clinical diversity. This guideline aims to be a comprehensive guide for healthcare workers in Southern Africa, offering practical insights into the epidemiology, pathogenesis, clinical manifestations, diagnostic testing, therapeutic principles, and public health responses to syphilis. Although the syphilis burden has declined over the years, recent data indicate a troubling resurgence, particularly among pregnant women and neonates. This guideline highlights the diagnostic challenges ...
Source: Southern African Journal of HIV Medicine - April 30, 2024 Category: African Health Authors: Remco P.H. Peters Source Type: research

A 3D atlas of the human developing pancreas to explore progenitor proliferation and differentiation
Conclusions/interpretationThis work presents a first 3D atlas of the human developing pancreas, charting both endocrine and proliferating cells across early development.Graphical Abstract (Source: Diabetologia)
Source: Diabetologia - April 29, 2024 Category: Endocrinology Source Type: research

No association between long-chain n-3 fatty acid intake during pregnancy and risk of type 1 diabetes in offspring in two large Scandinavian pregnancy cohorts
Conclusions/interpretationInitiation of a trial of EPA and DHA during pregnancy to prevent type 1 diabetes in offspring should not be prioritised.Graphical Abstract (Source: Diabetologia)
Source: Diabetologia - April 29, 2024 Category: Endocrinology Source Type: research

Race and Schizophrenia: Evidence for Epigenetics
Race is a socially constructed category and not explained by biological underpinnings. Persons racialized as Black experience greater racism and social disadvantage and have significantly elevated risks for schizophrenia than White individuals. Racial biases can also influence medical care and outcomes, including prenatal care. Adverse pregnancy outcomes like pre-term birth affect over 14% of US Blacks compared to 9.3% of US Whites, and are independently associated with the risk for schizophrenia, transmissible through mothers. (Source: Biological Psychiatry)
Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Dolores Malaspina, Yechiel Friedlander Source Type: research

Intergenerational Transmission of Maternal Life Stress and Sleep on Infant Neural Circuits and Behavioral Outcomes
This study applies an intergenerational framework to examine the relation between maternal childhood experiences, prenatal maternal sleep quality, neonatal white matter microstructure, and its impact on infant negative emotionality at six months. (Source: Biological Psychiatry)
Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Catherine Demers, Melissa Nevarez-Brewster, LillyBelle Deer, Mercedes Hoeflich Haase, Khalid Al-Ali, Maria Bagonis, John Gilmore, M. Camille Hoffman, Martin Styner, Benjamin Hankin, Elysia Davis Source Type: research