Serum Folate and Vitamin B12 Modify the Associations of N6AMT1 Genetic Variants with Gestational Diabetes Mellitus: A Cross-Sectional Study in Chinese Pregnant Women
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - April 17, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research
Adverse birth outcome among women who gave birth at the University of Gondar comprehensive specialized hospital, Northwest Ethiopia
In Ethiopia, various maternal and child health interventions, including comprehensive and basic obstetric cares were conducted to curb high neonatal and infant morbidity and mortality. As such, adverse birth o... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - April 17, 2024 Category: OBGYN Authors: Melak Jejaw, Getachew Teshale, Lake Yazachew, Endalkachew Dellie and Ayal Debie Tags: Research Source Type: research
Decision-making for congenital anomalies diagnosed during pregnancy: a narrative review
ConclusionMany factors contribute to an individual ’s decision-making after a diagnosis of a fetal anomalies diagnosed in the second trimester of pregnancy, ranging from personal beliefs and goals to shared experiences of others and access to care. Understanding how sources of information may be deemed both as facilitators and barriers to differen t individuals during the decision-making process is important for healthcare providers in order to understand how to most effectively support patients. There is a dearth of information on training healthcare professionals to provide support to patients facing these decisions. (...
Source: Journal of Assisted Reproduction and Genetics - April 17, 2024 Category: Reproduction Medicine Source Type: research
Klotho-mediated activation of the anti-oxidant Nrf2/ARE signal pathway affects cell apoptosis, senescence and mobility in hypoxic human trophoblasts: involvement of Klotho in the pathogenesis of preeclampsia
The anti-aging gene Klotho is implicated in the pathogenesis of preeclampsia (PE), which is a pregnancy disease characterized by hypertension and proteinuria. Oxidative stress is closely associated with the wo... (Source: Cell Division)
Source: Cell Division - April 17, 2024 Category: Cytology Authors: Baomei Xu, Fang Cheng and Xiaolei Xue Tags: Research Source Type: research
Effect of implementation of the WHO intrapartum care model on maternal and neonatal outcomes: a randomized control trial
This study aimed to determine the effects... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - April 17, 2024 Category: OBGYN Authors: Somayeh Abdolalipour, Shamsi Abbasalizadeh, Sakineh Mohammad-Alizadeh-Charandabi, Fatemeh Abbasalizadeh, Shayesteh Jahanfar, Fatemeh Raphi and Mojgan Mirghafourvand Tags: Research Source Type: research
Risk factors for relaparotomy after a cesarean delivery: a case-control study
Relaparotomy following a cesarean delivery (CD) is an infrequent complication, with inconsistency regarding risk factors and indications for its occurrence. We therefore aimed to determine risk factors and ind... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - April 17, 2024 Category: OBGYN Authors: Uri Amikam, Yael Botkovsky, Alyssa Hochberg, Aviad Cohen, Ishai Levin, Yariv Yogev, Liran Hiersch and Anat Lavie Tags: Research Source Type: research
Landscapes of gut bacterial and fecal metabolic signatures and their relationship in severe preeclampsia
Preeclampsia is a pregnancy-specific disease leading to maternal and perinatal morbidity. Hypertension and inflammation are the main characteristics of preeclampsia. Many factors can lead to hypertension and i... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - April 17, 2024 Category: Research Authors: Xianxian Liu, Xiaoming Zeng, Xing Li, Siming Xin, Feng Zhang, Faying Liu, Yang Zeng, Jilin Wu, Yang Zou and Xinwei Xiong Tags: Research Source Type: research
Seromolecular study on the prevalence and risk factors of Toxoplasma gondii infection in pregnant women referred to a gynecology hospital in Urmia, northwest part of Iran in 2022
Toxoplasmosis is a frequent infection among the human population. The infection can cause devastating complications for the fetus during pregnancy. The present study aimed to determine the serological and mole... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 17, 2024 Category: Infectious Diseases Authors: Nasim Bashour, Arash Aminpour, Shabnam Vazifehkhah and Rasool Jafari Tags: Research Source Type: research
Factors associated with malaria vaccine uptake in Nsanje district, Malawi
Malaria remains a significant global health burden affecting millions of people, children under 5 years and pregnant women being most vulnerable. In 2019, the World Health Organization (WHO) endorsed the intro... (Source: Malaria Journal)
Source: Malaria Journal - April 17, 2024 Category: Infectious Diseases Authors: Atusaye J. Simbeye, Save Kumwenda, Lauren M. Cohee, Dickens Omondi, Peninah K. Masibo, Hesborn Wao and Shehu S. Awandu Tags: Research Source Type: research
Hypertensive Pregnancy Supports Higher Adaptation of Stress Over Anemic Pregnancy: A Pilot Study
This study targets relative stress adaptation in pregnancy between hypertension and anemia. This study has been conducted on three types of pregnancies viz. regular, hypertensive and anemic pregnancy. The data obtained were compared against normal healthy controls. Bloo d pressure was monitored to label hypertensive pregnancy. Lipid profile was the severity marker for hypertensive subjects. Low hemoglobin and MCV levels were used as marker for anemia. Glycemic profile was verified by plasma glucose concentration to exclude diabetic subjects. BMI was calculated to e xclude obesity. Commercially available ELISA based kits we...
Source: Indian Journal of Clinical Biochemistry - April 17, 2024 Category: Biochemistry Source Type: research
Intimate Partner Violence and Antenatal Depression Among Underserved Pregnant Women
Journal of Women's Health, Ahead of Print. (Source: Journal of Women)
Source: Journal of Women - April 17, 2024 Category: OBGYN Authors: Xingpei Zhao Jihong Liu Monique J. Brown Kimberly Alston Source Type: research
Feasibility and reliability of fetal two dimensional speckle tracking echocardiography at 16 weeks gestational age: A pilot study
ConclusionsOur findings demonstrate that fetal 2D-STE analysis at 16 weeks gestational age is feasible when adhering to a strict protocol. However, further improvements are necessary to enhance the inter- and intra-operator reliability of 2D-STE at this gestational age. (Source: PLoS One)
Source: PLoS One - April 17, 2024 Category: Biomedical Science Authors: Thomas J. Nichting Source Type: research
Peri-implantitis with a potential axis to brain inflammation: an inferential review
This study found similarities between PI and PD development, maintenance, and in the bacterial agents located around the teeth (periodontitis) or dental implants (peri-implantitis). Through the cardiovascular system, these pathologies may also affect blood-brain barrier permeability. Furthermore, scientific evidence has suggested that microorganisms from PI (as in PD) can be recognized by trigeminal fiber endings and start inflammatory responses into the trigeminal ganglion. In addition, bacteria can traverse from the mouth to the brain through the lymphatic system. Consequently, the immune system increases inflammatory me...
Source: Odontology - April 17, 2024 Category: Dentistry Source Type: research
Medication use before and during pregnancy in Japan: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study
ConclusionWe found that ~ 50% of the pregnant women used medications before and during pregnancy and some took potential teratogenic medications during pregnancy. In birth genomic cohort study, it is expected that investigations into the safety and effectiveness of medications used during pregnancy will advance. (Source: European Journal of Clinical Pharmacology)
Source: European Journal of Clinical Pharmacology - April 17, 2024 Category: Drugs & Pharmacology Source Type: research
Aspirin versus metformin in pregnancies at high risk of preterm pre-eclampsia in China (AVERT): protocol for a multicentre, double-blind, 3-arm randomised controlled trial
This study will compare the incidence of preterm-PE with delivery at <37 weeks’ gestation, as the primary outcome, of three different interventional groups: (1) aspirin 75 mg daily, (2) aspirin 150 mg daily and (3) aspirin 75 mg with metformin 1.5 g daily. 957 participants per treatment group are required to detect a significant difference of 59% in the reduction of the incidence of preterm-PE with 80% power and type I error of 5%. Pregnancy and neonatal outcomes will be collected and analysed.
Ethics and dissemination
Ethical approval for the study was obtained from the Joint Chinese University of Hong Kong&ndas...
Source: BMJ Open - April 17, 2024 Category: General Medicine Authors: Liu, J., Shen, L., Nguyen-Hoang, L., Zhou, Q., Wang, C. C., Lu, X., Sahota, D., Chong, K. C., Ying, H., Gu, W., Zhou, R., Yang, H., Jiang, Y., Chen, D., Li, X., Poon, L. Tags: Open access, Obstetrics & Gynaecology Obstetrics and gynaecology Source Type: research
