Acute form of acne inversa in an 18-week pregnant patient: a case study.
Authors: Plagens-Rotman K, Przybylska R, Gerke K, Jaracz K, Serafinowska J, Sadowska-Przytocka A, Adamski Z, Czarnecka-Operacz M PMID: 31320864 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - July 21, 2019 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Maternal immunization in Malawi: A mixed methods study of community perceptions, programmatic considerations, and recommendations for future planning.
CONCLUSIONS: Lessons from the successful delivery of maternal tetanus immunization in Malawi may be informative for similar countries considering new vaccines for pregnant women or striving to optimize the delivery of those currently provided. PMID: 31319932 [PubMed - in process] (Source: Vaccine)
Source: Vaccine - July 21, 2019 Category: Allergy & Immunology Authors: Fleming JA, Munthali A, Ngwira B, Kadzandira J, Jamili-Phiri M, Ortiz JR, Lambach P, Hombach J, Neuzil KM, Stepanchak M, Bhat N Tags: Vaccine Source Type: research

The role of Zeb1 in the pathogenesis of morbidly adherent placenta.
In conclusion, these findings indicated that Zeb1 may promote placental implantation by activating the Akt signaling pathway, thus providing a theoretical basis for investigating the causes of MAP. PMID: 31322233 [PubMed - as supplied by publisher] (Source: Molecular Medicine Reports)
Source: Molecular Medicine Reports - July 21, 2019 Category: Molecular Biology Tags: Mol Med Rep Source Type: research

Perspectives on HIV partner notification, partner HIV self-testing and partner home-based HIV testing by pregnant and postpartum women in antenatal settings: a qualitative analysis in Malawi and Zambia.
CONCLUSIONS: Most stakeholders considered different approaches to partner HIV testing to be acceptable, but concerns were raised about each. A choice-based approach may allow women to select their preferred method of partner testing; however, implementation challenges need to be addressed. PMID: 31321884 [PubMed - in process] (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - July 20, 2019 Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research

Vaginal-perineal cultures for detecting group B streptococci and extended spectrum β-lactamase producing bacteria in pregnancy
ConclusionsThe GBS detection rate of the vagino-perineal swab was lower compared to the reference standard. However, agreement between the two screening methods was high and there were no cases of GBS neonatal sepsis in the recruited population, supporting this less invasive screening strategy. In contrast, the vaginal-perineal swab was inferior to the rectal swab for detecting ESBL-E, indicating that this less invasive method for detecting antibiotic resistant bacteria that may be potentially transferred to the neonate during labor and delivery would be inappropriate for ESBL-E screening in pregnant women. The low ESBL-E ...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - July 20, 2019 Category: OBGYN Source Type: research

Phthalate Exposure from Drugs during Pregnancy and Possible Risk of Preterm Birth and Small for Gestational Age
CONCLUSIONExposure to some phthalate-containing pharmaceutical drugs during third trimester is associated with preterm birth. (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - July 20, 2019 Category: OBGYN Source Type: research

Factors associated with multidrug-resistant bacteria in a cohort of patients with asymptomatic bacteriuria who underwent urological surgery
ConclusionsBacterial resistance is frequent among patients with ASB and planned urological procedures. Advanced age and prior hospitalization should be borne in mind for patients with planned urological procedures because they are factors associated with the presence of MDR bacteria. (Source: American Journal of Infection Control)
Source: American Journal of Infection Control - July 20, 2019 Category: Infectious Diseases Source Type: research

Antihepatitis B Surface Antigen and Hepatitis C Antibodies among Pregnant Women in an Urban Area of Mwanza City, Tanzania.
Conclusion: A significant proportion of pregnant women have anti-HBs while the seroprevalence of HCV is low among pregnant women in the city of Mwanza. Routine screening of HBV among pregnant women coupled with appropriate management should be emphasized in developing countries. Further studies to determine seroprevalence of HCV are recommended across the country. PMID: 31316835 [PubMed - in process] (Source: Journal of Pregnancy)
Source: Journal of Pregnancy - July 20, 2019 Category: OBGYN Tags: J Pregnancy Source Type: research

Demographics of Women with Type 1 Dm, Type 2 Dm and Gestational Diabetes Attending A Diabetes and Pregnancy Clinic 2000-2002; 2010-2012 and 2014-2016
Publication date: Available online 19 July 2019Source: Canadian Journal of DiabetesAuthor(s): P. Khanna, L. Chow, E. Brydges, K. Anukum, S. Liu, J.L. Mahon, T. Joy, R. McManusAbstractPregnancies complicated by diabetes are increasingly frequent. The Endocrine and Pregnancy Clinic [EPC] at St Joseph’s Health Care London is the stable, local provider of all outpatient pregnancy diabetes care, thereby providing an opportunity to document patient characteristics with time.MethodsEPC charts were reviewed for: 2000-2002; 2010-2012; 2014-2016 documenting DM type (T1DM, T2DM, GDM); age; weight; year/week of DM diagnosis; med...
Source: Canadian Journal of Diabetes - July 20, 2019 Category: Endocrinology Source Type: research

Current Policies and Practicing Surgeon Perspectives on Parental Leave
Publication date: Available online 19 July 2019Source: The American Journal of SurgeryAuthor(s): Tyler Gaines, Nina Harkhani, Hegang Chen, Rena D. MalikAbstractBackgroundThe aim of this study is to evaluate the components of current parental leave policies in surgical practice and evaluate surgeon perceptions of parental leave.MethodsPracticing surgeons were recruited to complete a survey via social media outlets and e-mail. Participants were asked questions regarding existing policies and their perspectives towards parental leave.ResultsThe survey was completed by 431 surgeons, of which 90% were female and 45% in academic...
Source: The American Journal of Surgery - July 20, 2019 Category: Surgery Source Type: research

Interactions between the complement and endothelin systems in normal pregnancy and following placental ischemia
Publication date: October 2019Source: Molecular Immunology, Volume 114Author(s): Jean F. Regal, Jenna M. Lund, Cameron R. Wing, Kate M. Root, Luke McCutcheon, Lynne T. Bemis, Jeffrey S. Gilbert, Sherry D. FlemingAbstractPreeclampsia is characterized by new onset hypertension and fetal growth restriction and is associated with aberrant activation of the innate immune complement system and stressed or ischemic placenta. Previous studies have suggested a role for both endothelin and complement system activation products in new onset hypertension in pregnancy, but inter-relationships of the pathways are unclear. We hypothesize...
Source: Molecular Immunology - July 20, 2019 Category: Allergy & Immunology Source Type: research

Neurological Emergencies in Pregnancy.
This article reviews the clinical features and management of some of the common severe neurological emergencies in pregnancy. PMID: 31315330 [PubMed - in process] (Source: Journal of the Association of Physicians of India)
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Evaluation of Plasma Homocysteine Levels in Patients of PCOS.
The objective was to evaluate the relationship between insulin resistance and serum homocysteine in subjects with polycystic ovarian syndrome (PCOS). Material and Methods: Cross sectional Case Control observational study done in Department of Obstetrics and Gynecology, KGMU Lucknow. Cases were 50 PCOS women as a study group and 40 women with infertility due to isolated male cause as a control group. Serum homocysteine levels compared in PCOS patients. Results: Mean homocysteine raised in cases (11.8 ± 5.5μmol/L) than control (7.8 ± 2.2 μmol/L), p
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Evaluation of serum Glutathione-S Transferase-Alpha as a Biomarker of Intrahepatic Cholestasis of Pregnancy.
Authors: Shukla A, Saxena P, Yadav A Abstract Objective: To evaluate if serum Glutathione-S Transferase-Alpha (GSTA) can be used as a biomarker of intrahepatic cholestasis of pregnancy (IHCP). Methods: 45 pregnant women with IHCP and 45 age and weight matched pregnant women as controls were enrolled and liver function tests including serum GSTA were measured. All cases and controls were followed for their maternal and foetal outcomes till delivery. Statistical analysis included unpaired t test, Mann-Whitney test and chi square test. Results: IHCP group showed higher mean serum GSTA concentrations compared t...
Source: Journal of the Association of Physicians of India - July 20, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Use of antiepileptic drugs in women of fertile age.
CONCLUSIONS: The overall use of AEDs in women of fertile age and pregnant women has increased in the past 16 years, especially due to an increased use of lamotrigine. However, valproate use in pregnant women and in younger women of fertile age has become less frequent. FUNDING: This study received funding from the Lundbeck Foundation, the Danish Epilepsy Association, the Central Denmark Region and the Novo Nordisk Foundation (NNF16OC0019126). TRIAL REGISTRATION: none. PMID: 31315793 [PubMed - in process] (Source: Danish Medical Journal)
Source: Danish Medical Journal - July 20, 2019 Category: General Medicine Tags: Dan Med J Source Type: research

Tubo-Ovarian Abscesses in Nonsexually Active Adolescents: A Rare but Consequential Miss
A tubo-ovarian abscess (TOA) is an emergent and potentially life-threatening illness. Rapid administration of antibiotics, interventional radiology abscess drainage, and/or gynecologic surgery are critical interventions. The goal is to prevent abscess rupture, which can lead to peritonitis, severe sepsis, recurrent hospitalizations, and, in rare circumstances, death [1]. Although mortality from TOA in the U.S. is uncommon, the result of an untreated TOA can have lasting damaging effects to pelvic organs and increase the risk of infertility, ectopic pregnancy, ovarian vein thrombosis, and chronic pelvic pain [2]. (Source: J...
Source: Journal of Adolescent Health - July 20, 2019 Category: Child Development Authors: Lauren S. Chernick Tags: Editorial Source Type: research

Development and validation of the predictive models for the QUiPP App v.2: a tool for predicting preterm birth in high-risk asymptomatic women.
CONCLUSION: QUiPP app version 2 is a highly accurate prediction tool for prematurity, based on a unique combination of biomarkers, symptoms and statistical algorithm. It can reliably be used in the context of discussing risk. Whilst further work is required to determine its role in identifying women requiring prophylactic interventions, it is a reliable and convenient screening tool for planning follow-up or hospitalisation for high risk women. This article is protected by copyright. All rights reserved. PMID: 31325332 [PubMed - as supplied by publisher] (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - July 20, 2019 Category: Radiology Authors: Watson HA, Seed PT, Carter J, Hezelgrave NL, Kuhrt K, Tribe RM, Shennan AH Tags: Ultrasound Obstet Gynecol Source Type: research

Risks of Cause-specific Mortality in Offspring of Pregnancies Complicated by Hypertensive Disease of Pregnancy
Fetal environment has a substantial influence on an individual ’s health throughout their life course. Animal models of hypertensive disease of pregnancy (HDP) have demonstrated adverse health outcomes among offspring exposed to HDP in utero. While there are numerous descriptions of the neonatal, infant, and pediatric outcomes of human offspring affected by H DP, there are few data in United States populations on later life outcomes, including mortality. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 20, 2019 Category: OBGYN Authors: Ibrahim A. Hammad, Huong Meeks, Alison Fraser, Lauren H. Theilen, M. Sean Esplin, Ken R. Smith, Michael W. Varner Tags: Original Research: Obstetrics Source Type: research

Maternal surgery during pregnancy has a transient adverse effect on the developing fetal rabbit brain
Recently the US Food and Drug Administration called for cautious use of anesthetic drugs during pregnancy. In 0.2-2% of pregnancies non-obstetric surgery is being performed. The consequences of anesthesia during pregnancy on fetal development remain unclear and preclinical studies in relevant animal models may help elucidate that. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - July 20, 2019 Category: OBGYN Authors: Lennart Van der Veeken, Johannes Van der Merwe, Sarah Devroe, Annalisa Inversetti, Angela Galgano, Tom Bleeser, Roselien Meeusen, Steffen Rex, Jan Deprest Tags: Meeting Papers: SMFM Papers Source Type: research

Binge drinking during pregnancy and psychosis-like experiences in the child at age 11
AbstractIncreased frequency of psychosis-like experiences (PLEs) has been previously reported in children born to mothers with high general levels of alcohol intake during pregnancy. The aim of this study was to examine whether the risk of PLEs was likewise elevated in children prenatally exposed to binge drinking. Participants were 44,326 children and their mothers enrolled in the Danish National Birth Cohort from 1996 –2002. Information on maternal binge drinking was collected twice in pregnancy by telephone interview and PLEs in the children were ascertained in a Web-based questionnaire at age 11. Analyses were ca...
Source: European Child and Adolescent Psychiatry - July 20, 2019 Category: Psychiatry Source Type: research

Recommendations of the Polish Psychiatric Association regarding the treatment of affective disorders in women of childbearing age. Part II: Bipolar disorder.
Authors: Rybakowski J, Cubała WJ, Gałecki P, Rymaszewska J, Samochowiec J, Szulc A, Dudek D Abstract In the article, the recommendations of the Polish Psychiatric Association regarding pharmacological treatment of women with bipolar disorder during pregnancy and postpartum period were presented. The issue pertains to every twentieth woman wanting to get pregnant. Before planned pregnancy, it is advisable to obtain a several-month stabilization of psychiatric state, to establish treatment with one mood-stabilizing drug (except for valproate and carbamazepine) or gradual discontinuation of drugs in case of mild cou...
Source: Psychiatria Polska - July 19, 2019 Category: Psychiatry Tags: Psychiatr Pol Source Type: research

Recommendations of the Polish Psychiatric Association for treatment of affective disorders in women of childbearing age. Part III: Approach to pregnancy loss and unsuccessful in vitro treatment of infertility.
This article presents recommendations of the Polish Psychiatric Association regarding approach to pregnancy loss and unsuccessful in vitro treatment of infertility. From the psychological perspective pregnancy loss and perinatal death are amongst the most stressful events in human life - carrying increased risk of developing affective, anxiety or post-traumatic stress disorders. Psychologists, physicians and the rest of the medical staff should provide integrated and individualized care which should be based on respect, empathy and expertise. The necessary phases of support for women experiencing pregnancy loss are: (1) ph...
Source: Psychiatria Polska - July 19, 2019 Category: Psychiatry Tags: Psychiatr Pol Source Type: research

Adverse outcomes during pregnancy and major congenital malformations in infants of patients with bipolar and schizoaffective disorders treated with antiepileptic drugs: A systematic review.
CONCLUSIONS: AEDs may produce adverse outcomes in pregnancy and MCM in children of pregnant women with BD or SAD, showing higher risks at higher doses. LTG could be considered in this type of patients, given the low rate of adverse events. VPA and CBZ use should be avoided during pregnancy. PMID: 31317955 [PubMed - in process] (Source: Psychiatria Polska)
Source: Psychiatria Polska - July 19, 2019 Category: Psychiatry Tags: Psychiatr Pol Source Type: research

Recommendations of the Polish Psychiatric Association for treatment of affective disorders in women of childbearing age. Part I: Treatment of depression.
Authors: Samochowiec J, Rybakowski J, Galecki P, Szulc A, Rymaszewska J, Cubiała WJ, Dudek D Abstract Treatment of depressive disorders in women of childbearing age requires special attention due to the possibility of planned or unplanned pregnancy and the specificity of mood disorders associated with the perinatal period. A doctor who treats depression in a woman of childbearing age should openly discuss with the patient her sexuality and the possibility of becoming pregnant. A psychiatrist may encounter various problems, such as: a therapeutic decision regarding a woman suffering from recurrent depression who re...
Source: Psychiatria Polska - July 19, 2019 Category: Psychiatry Tags: Psychiatr Pol Source Type: research

Pregnancy outcomes after thyroid cancer
Journal Name: Journal of Perinatal Medicine Issue: Ahead of print (Source: Journal of Perinatal Medicine)
Source: Journal of Perinatal Medicine - July 19, 2019 Category: Perinatology & Neonatology Source Type: research

The authors reply
Timmermans and colleagues1 report on a small series of 43 patients with secondary hemolytic uremic syndrome (HUS) related mainly to  hypertensive emergency, pregnancy, and kidney transplantation. The incidence of complement gene variants was highly variable between HUS subtypes. The authors raise the issue that in our larger cohort of secondary HUS we did not include patients with hypertensive emergency, pregnancy, and kidney t ransplantation. These types of HUS were excluded from our analysis for several reasons. (Source: Kidney International)
Source: Kidney International - July 19, 2019 Category: Urology & Nephrology Authors: Alice Le Clech, V éronique Frémeaux-Bacchi, Fadi Fakhouri Tags: Letter to the Editor Source Type: research

Perceived discrimination and risk of preterm birth among Turkish immigrant women in Germany
Publication date: Available online 19 July 2019Source: Social Science & MedicineAuthor(s): Laura Scholaske, Annette Brose, Jacob Spallek, Sonja EntringerAbstractBackgroundHealth disparities, including adverse birth outcomes, exist between Turkish immigrants and the autochthonous population in Germany. The state of research on the risk of preterm birth (PTB, defined as
Source: Social Science and Medicine - July 19, 2019 Category: Psychiatry & Psychology Source Type: research

Identification and Management of rare causes of chronic hypertension in pregnancy in a tertiary referral centre of North India
Publication date: Available online 18 July 2019Source: Pregnancy HypertensionAuthor(s): Sangeeta Yadav, Neeta Singh, Shruti Jain, Mandakini Pradhan (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - July 19, 2019 Category: OBGYN Source Type: research

Progestogens and immunology
Publication date: Available online 5 July 2019Source: Best Practice & Research Clinical Obstetrics & GynaecologyAuthor(s): J. Szekeres-Bartho, A.E. SchindlerAbstractFifty percent of fetal antigens are of paternal origin. These are recognized by the maternal immune system, thereby resulting in lymphocyte activation and the induction of progesterone receptors (PRs) in immune cells. Upon binding of progesterone to PRs on lymphocytes, a downstream mediator called progesterone-induced blocking factor (PIBF) is produced. The full-length PIBF is a 90 kDa protein; however, because of alternative splicing, several smal...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - July 19, 2019 Category: OBGYN Source Type: research

Cannabidiol improves behavioural and neurochemical deficits in adult female offspring of the maternal immune activation (poly I:C) model of neurodevelopmental disorders
Publication date: Available online 19 July 2019Source: Brain, Behavior, and ImmunityAuthor(s): Ashleigh L. Osborne, Nadia Solowij, Ilijana Babic, Jeremy S. Lum, Xu-Feng Huang, Kelly A. Newell, Katrina Weston-GreenAbstractCognitive impairment is a major source of disability in schizophrenia and current antipsychotic drugs (APDs) have minimal efficacy for this symptom domain. Cannabidiol (CBD), the major non-intoxicating component of Cannabis sativa L., exhibits antipsychotic and neuroprotective properties. We recently reported the effects of CBD on cognition in male offspring of a maternal immune activation (polyinosinic-po...
Source: Brain, Behavior, and Immunity - July 19, 2019 Category: Neurology Source Type: research

Avoid making a mountain out of an invasive hydatidiform mole: do a pregnancy test!
Publication date: 20–26 July 2019Source: The Lancet, Volume 394, Issue 10194Author(s): Reda Hemida, Helena C van Doorn (Source: The Lancet)
Source: The Lancet - July 19, 2019 Category: General Medicine Source Type: research

Gestational weight gain, nutritional status and blood pressure in pregnant women
ABSTRACT OBJECTIVE To evaluate whether weekly gestational weight gain is associated with anemia, vitamin A insufficiency, and blood pressure levels in the third trimester of pregnancy. METHODS A prospective study with 457 pregnant women attending primary care in Cruzeiro do Sul, Acre. The weekly gestational weight gain rate measured between the second and third trimesters was classified as insufficient, adequate, and excessive according to the recommendations of the Institute of Medicine 2009. The outcomes at the beginning of the third gestational trimester were: anemia (Hb
Source: Revista de Saude Publica - July 19, 2019 Category: International Medicine & Public Health Source Type: research

Nonsurgical Management of Interstitial Pregnancies: Feasibility and Predictors of Treatment Failure
ConclusionSuccessful nonsurgical management of an interstitial pregnancy is feasible, although appropriate selection of cases is advised. A large gestational sac is a risk factor for treatment failure and should prompt surgical intervention. Subsequent pregnancies can generally be considered safe and with a favorable outcome. (Source: Journal of Minimally Invasive Gynecology)
Source: Journal of Minimally Invasive Gynecology - July 19, 2019 Category: OBGYN Source Type: research

Is there an impact of feet position on squatting birth position? An innovative biomechanical pilot study
The squatting birth position is widely used for “natural” birth or in countries where childbirth occurs in non-medical facilities. Squatting birth positions, like others, are roughly defined so a biomechanical... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - July 19, 2019 Category: OBGYN Authors: David Desseauve, Laetitia Fradet, Patrick Lacouture and Fabrice Pierre Tags: Research article Source Type: research

A simple model to predict risk of gestational diabetes mellitus from 8 to 20  weeks of gestation in Chinese women
Gestational diabetes mellitus (GDM) is associated with adverse perinatal outcomes. Screening for GDM and applying adequate interventions may reduce the risk of adverse outcomes. However, the diagnosis of GDM d... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - July 19, 2019 Category: OBGYN Authors: Tao Zheng, Weiping Ye, Xipeng Wang, Xiaoyong Li, Jun Zhang, Julian Little, Lixia Zhou and Lin Zhang Tags: Research article Source Type: research

Erratum
An author name was misspelled in the article “Endoscopic intervention and cholecystectomy in pregnant women with acute biliary pancreatitis decrease early readmissions,” published in the June issue of Gastrointestinal Endoscopy (Gastrointest Endosc 2019;89:1169-77). The correct spelling is Jeffery R. Groce, MD. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - July 19, 2019 Category: Gastroenterology Tags: Erratum Source Type: research

Management of hypertension in pregnancy - prevention, diagnosis, treatment and long-term prognosis.
ska-Małek M, Stolarz-Skrzypek K, Szczepaniak-Chicheł L, Szyndler A, Wolf J, Wielgoś M, Hoffman P, Januszewicz A PMID: 31322138 [PubMed - as supplied by publisher] (Source: Polish Heart Journal)
Source: Polish Heart Journal - July 19, 2019 Category: Cardiology Authors: Prejbisz A, Dobrowolski P, Kosiński P, Bomba-Opoń D, Adamczak M, Bekiesińska-Figatowska M, Kądziela J, Konopka A, Kostka-Jeziorny K, Kurnatowska I, Leszczyńska-Gorzelak B, Litwin M, Olszanecka A, Orczykowski M, Poniedziałek-Czajkowska E, Sobieszcza Tags: Kardiol Pol Source Type: research

Transcriptomic Evidence that Cortisol Alters Perinatal Epicardial Adipose Tissue Maturation.
This study investigates the effects of cortisol on epicardial adipose tissue (EAT), a visceral fat pad associated with adverse cardiovascular conditions in adults. Pregnant ewes were treated with either 1 mg/kg/day cortisol from 115 days gestation to term and EAT collected from term fetuses (control: n=8, maternal cortisol 1 mg/kg/day: n=6). To compare the effects of cortisol to the normal maturation in EAT, we also modeled the normal changes in gene expression in EAT at the transition from in utero to postnatal life using the EAT from control fetuses and from two-week-old lambs (control: n=7).), Transcriptomic modeling wa...
Source: American Journal of Physiology. Endocrinology and Metabolism - July 19, 2019 Category: Physiology Authors: Richards EM, McElhaney E, Zeringue K, Joseph S, Keller-Wood M Tags: Am J Physiol Endocrinol Metab Source Type: research

Cortical development in fetuses with congenital heart defects using an automated brain ‐age prediction algorithm
ConclusionsThis study shows that fetuses with isolated cases of congenital heart defects show some delay in cortical maturation as compared to healthy control cases. The clinical relevance of this small difference is debatable. This finding was consistent throughout pregnancy and did not progress during the third trimester.This article is protected by copyright. All rights reserved. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - July 19, 2019 Category: OBGYN Authors: Sheila M. P. Everwijn, Ana I. L. Namburete, Nan van Geloven, Fenna A. R. Jansen, Aris T. Papageorghiou, Alison J. Noble, Aalbertine K. K. Teunissen, Lieke Rozendaal, Nico A. Blom, Jan M. M. van Lith, Monique C. Haak Tags: Original Research Article Source Type: research

From β-hCG values to counseling in tubal pregnancy: what do women want?
. (Source: Gynecological Endocrinology)
Source: Gynecological Endocrinology - July 19, 2019 Category: Endocrinology Authors: Lorenzo Sabbioni Emanuela Carossino Filiberto Maria Severi Stefano Luisi Source Type: research

Endometrium immunomodulation by intrauterine insemination administration of treated peripheral blood mononuclear cell prior frozen/thawed embryos in patients with repeated implantation failure.
Abstract SummaryIn assisted reproductive technology (ART) programmes, approximately 10% of infertile patients have at least two or three repeated implantation failures (RIFs) after an in vitro fertilization (IVF) protocol. Successful implantation mainly depends on local immune tolerance mechanisms involving a spectrum of cytokines, interleukins and growth factors. The latter have played pivotal roles in the recruitment of immune cells (and notably T-lymphocyte cells). In total, 250 couples participating in frozen-thawed embryo transfer programme were incorporated in a randomized clinical trial (peripheral blood mo...
Source: Zygote - July 19, 2019 Category: Reproduction Medicine Authors: Nobijari FF, Arefi SS, Moini A, Taheripanah R, Fazeli E, Kharazi H, Hosseini SZ, Hosseini A, Valojerdi MR, Copin H, Benkhalifa M Tags: Zygote Source Type: research

Palliative Care and the Pregnant Surgical Patient
Obstetricians and general surgeons frequently navigate the challenges of providing surgical care that is mindful of the unique circumstances of pregnancy. Ensuring pregnant patients have high-quality surgical care is an ethical imperative. Providers should maintain a high index of suspicion for surgical disease to ensure that surgical diagnoses are not missed or inadequately treated. A variety of imaging modalities are used in pregnancy. Surgical management includes laparoscopic and open approaches. Perioperative fetal monitoring should be the subject of multidisciplinary discussion. Symptomatic control in pregnancy should...
Source: Surgical Clinics of North America - July 19, 2019 Category: Surgery Authors: Benjamin P. Brown, Roxane Holt Source Type: research

Placental mesenchymal dysplasia, a rare pathology
We report a case of a 16 year old primigravida referred to our center with a previous diagnosis of molar pregnancy and a 160/100 mmHg blood pressure at 28 weeks of gestation. On examination, she was noted to have 41 centimeters symphysis-fundal height, abdominal tenderness, diffuse bilateral edema in her lower extremities and hyperreflexia. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 19, 2019 Category: OBGYN Authors: Roberto L ópez Quintana, Carlos Armando Félix Baez, Francisco Alberto Leyva Moraga, Eduardo Leyva Moraga, José Heliodoro Gonzáles Zepeda, Rafael Enrique Anaya Manjarrez Tags: Short communication Source Type: research

Phthalate Exposure from Drugs during Pregnancy and Possible Risk of Preterm Birth and Small for Gestational Age
Phthalates are chemical compounds present in a wide range of consumer products and are thought to be endocrine disruptors. Though not commonly known, phthalates are present in some medication with previous studies finding up to 50-fold higher urinary metabolite concentrations among exposed compared to the general population. Previous studies on environmental phthalate exposure and pregnancy outcomes have been contradictory and inconclusive and all previous studies have assessed phthalate exposure using biomarkers despite a known rapid metabolism of phthalates. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 19, 2019 Category: OBGYN Authors: Anne Broe, Anton Potteg ård, Jesper Hallas, Thomas Patrick Ahern, Ronald Francis Lamont, Per Damkier Source Type: research

Vaginal-perineal cultures for detecting group B streptococci and extended spectrum β-lactamase producing bacteria in pregnancy
To compare the detection rates of vaginal-perineal cultures for group B streptococci (GBS) with the standard vaginal and rectal cultures and evaluate the diagnostic yield of vaginal-perineal vs. rectal swabs for extended spectrum β-lactamase producing Enterobacterales (ESBL-E) during the third trimester of pregnancy. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 19, 2019 Category: OBGYN Authors: Dorothy J. Huang, Irene H ösli, Sarah Tschudin-Sutter, Tabea Pfister, Christina Granado, Doris Müller-Borer, Andreas Schötzau, R. Frei, Marc Dangel, Evelyn A. Huhn, Andreas Widmer, Danielle Vuichard-Gysin Tags: Full length article Source Type: research

Use of Transnasal Rapid-Insufflation Ventilatory Exchange (THRIVE) to facilitate the management of subglottic stenosis in pregnancy
Subglottic stenosis is characterised by narrowing of the lower larynx and upper trachea. Conventional intubation can be impossible, whilst in the parturient the anatomical and physiological changes of pregnancy further complicate management. (Source: International Journal of Obstetric Anesthesia)
Source: International Journal of Obstetric Anesthesia - July 19, 2019 Category: Anesthesiology Authors: S. Bour, P. Milligan, A.F. McNarry Tags: Case report Source Type: research

IJERPH, Vol. 16, Pages 2579: Maternal and Child Nutrition and Oral Health in Urban Vietnam
Susan L. Ivey The global nutrition transition has contributed to child obesity and dental caries in developing countries, including Vietnam. Few studies have described the nutrition and oral health of mothers and children. This a descriptive study of the nutrition and oral health characteristics of a convenience sample of 571 children aged 2 to 5 years and their mothers from 5 urban preschools in Central and South Vietnam. The mothers completed a written survey, and the children received dental exams and weight/height measurements. High rates of bottle-feeding and the consumption of sweets were reported. One in 4 chi...
Source: International Journal of Environmental Research and Public Health - July 19, 2019 Category: Environmental Health Authors: Debbie Huang Karen Sokal-Gutierrez Kenny Chung Wenting Lin Linh Ngo Khanh Raymond Chung Hung Trong Hoang Susan L. Ivey Tags: Article Source Type: research

Magnitude of low birth weight and maternal risk factors among women who delivered in Debre Tabor Hospital, Amhara Region, Ethiopia: a facility based cross-sectional study
AbstractBackgroundSurvival of newborns and long term complications are highly correlated with birth weight. The low birth weight rate is an indicator of a public health problem that includes long-term maternal malnutrition, ill health, and poor health care at population level during pregnancy. On an individual basis, low birth weight is an important predictor of newborn health and survival. We aimed to assess the magnitude of low birth weight and its associated factors among women who delivered in Debre Tabor Hospital (DTH), Amhara, Ethiopia.MethodsFacility based cross sectional study was employed on 282 mothers who delive...
Source: Italian Journal of Pediatrics - July 19, 2019 Category: Pediatrics Source Type: research

Air Pollution, Oxidative Stress, and Diabetes: a Life Course Epidemiologic Perspective
AbstractPurpose of ReviewAmbient air pollution is strongly linked to cardiovascular and respiratory diseases. We summarize available published evidence regarding similar associations with diabetes across the life course.Recent FindingsWe performed a life-course survey of the recent literature, including prenatal, gestational, childhood/adolescence, and adult exposures to air pollution. Oxidative stress is identified as a key factor in both metabolic dysfunction and the effects of air pollution exposure, especially from fossil fuel combustion products, providing a plausible mechanism for air pollution-diabetes associations....
Source: Current Diabetes Reports - July 19, 2019 Category: Endocrinology Source Type: research

Residual inflammatory risk in coronary heart disease: incidence of elevated high-sensitive CRP in a real-world cohort
This study aims to identify the share of patients with coronary heart disease (CHD) and residual inflammation who may benefit from anti-inflammatory therapy.MethodshsCRP and low-density lipoprotein (LDL) levels were determined in 2741 all-comers admitted to the cardiological ward of our tertiary referral hospital between June 2016 and June 2018. Patients without CHD, with acute coronary syndrome, chronic or recurrent systemic infection, use of immunosuppressant or anti-inflammatory agents, chronic inflammatory diseases, chemotherapy, terminal organ failure, traumatic injury and pregnancy were excluded.Results856 patients w...
Source: Clinical Research in Cardiology - July 19, 2019 Category: Cardiology Source Type: research