Live birth derived from a markedly large polar body oocyte: a rare case report
In this study, it is revealed for the first time that a huge PB1 oocyte can be fertilized, resulting in the growth of a blastocyst, a subsequent pregnancy, and a live birth. This new information prompts us to reconsider the use of large PB1 oocytes. More insightful talks should be given attention to prevent the waste of embryos because not all oocytes with aberrant morphology are unavailable.PMID:38619002 | DOI:10.1017/S0967199424000054 (Source: Zygote)
Source: Zygote - April 15, 2024 Category: Reproduction Medicine Authors: Yongxiang Liu Xinliang Peng Caifeng Liu Shuting Zhang Zhiwei Weng Li Yu Shaohu Zhou Xuekun Huang Source Type: research

The NF κB Signaling Pathway Is Involved in the Pathophysiological Process of Preeclampsia
Geburtshilfe Frauenheilkd. 2024 Apr 10;84(4):334-345. doi: 10.1055/a-2273-6318. eCollection 2024 Apr.ABSTRACTThe high prevalence of preeclampsia (PE) is a major cause of maternal and fetal mortality and affects the long-term prognosis of both mother and baby. Termination of pregnancy is currently the only effective treatment for PE, so there is an urgent need for research into its pathogenesis and the development of new therapeutic approaches. The NFκB family of transcription factors has an essential role in inflammation and innate immunity. In this review, we summarize the role of NFκB in normal and preeclampsia pregnan...
Source: Geburtshilfe und Frauenheilkunde - April 15, 2024 Category: OBGYN Authors: Yaxi Li Qinying Zhu Ruifen He Junhong Du Xue Qin Yi Li Xiaolei Liang Jing Wang Source Type: research

Is Appendectomy During Late Stages of Pregnancy Associated with an Increased Cesarean Delivery Rate? - a Retrospective Analysis of One Center During 10 Years
CONCLUSION: In this small monocentric cohort, only open appendectomies were performed. Our data indicate that it is safe to perform open appendectomy during pregnancy if necessary. In this small patient group, there was an increase in simultaneous cesarean deliveries.PMID:38618579 | PMC:PMC11006560 | DOI:10.1055/a-2273-2672 (Source: Geburtshilfe und Frauenheilkunde)
Source: Geburtshilfe und Frauenheilkunde - April 15, 2024 Category: OBGYN Authors: Julia Kummer Josefine Koenigbauer Falko Stephan Joachim Peters Christian Rickert Lars Hellmeyer Source Type: research

Low Estradiol Level and Endometrial Thickness on the Day of Endometrial Transformation Influence Clinical Pregnancy After Intrauterine Insemination
(Source: International Journal of General Medicine)
Source: International Journal of General Medicine - April 15, 2024 Category: General Medicine Tags: International Journal of General Medicine Source Type: research

Sarcoidosis in pregnancy
Key content: Sarcoidosis is an uncommon multi-system disorder characterised by the presence of non-caseating granulomas. It has a peak incidence between the ages of 20 –40 years old. The pathogenesis of sarcoidosis is uncertain; however, it is known to be associated with an exaggerated T helper 1 (TH1) immune response leading to systemic inflammation and granuloma formation. Suppression in TH1 responses in pregnancy leads to disease remission in the majority of pregnancies. Nevertheless, the potential for decompensation in a subgroup remains, and  consideration should be given to the pre-pregnancy state. Sarcoidos...
Source: The Obstetrician and Gynaecologist - April 15, 2024 Category: OBGYN Authors: Joshua Odendaal, Fiona L Mackie, Sofia Tosounidou, Swati Ghosh, Ellen Knox Tags: Review Source Type: research

Comparison of pregnancy outcomes among patients of different ages who underwent frozen-thawed high-quality single blastocyst transfer
To investigate the feasibility of performing frozen-thawed high-quality single blastocyst transfer in women of different ages. (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - April 15, 2024 Category: OBGYN Authors: Haoying Chen, Shenghao Wu, Weijue Su, Junzhao Zhao and Yanhong Wu Tags: Research Source Type: research

Evaluation of incision healing status after transverse uterine fundal incision for cesarean delivery and postoperative pregnancy: a ten-year single-center retrospective study
Transverse uterine fundal incision (TUFI) is a beneficial procedure for mothers and babies at risk due to placenta previa-accreta, and has been implemented worldwide. However, the risk of uterine rupture durin... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - April 15, 2024 Category: OBGYN Authors: Fumikazu Kotsuji, Takashi Shibata, Satoshi Nakago, Hiroki Kato, Sayoko Hosono, Yasunori Fukuoka and Koji Nishijima Tags: Research Source Type: research

Epidemiological and virological surveillance of the prevention of mother-to-child transmission of HIV among pregnant women in Togo
In 2015, Togo introduced the “test-and-treat” strategy for the prevention of mother-to-child transmission (PMTCT) of HIV. Pediatric HIV infection remains a public health problem in Togo, with a mother-to-child... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - April 15, 2024 Category: OBGYN Authors: Kokou Tegueni, Fifonsi Adjidossi Gbeasor-Komlanvi, Oumarou I. Wone Adama, Arnold Junior Sadio, Amivi Phyllis Amenyah-Ehlan, Claver Anoumou Dagnra and Didier Koumavi Ekouevi Tags: Research Source Type: research

A high fiber diet or supplementation with Lactococcus lactis subspecies cremoris to pregnant mice confers protection against intestinal injury in adult offspring
Volume 16, Issue 1, January-December 2024 . (Source: Gut Microbes)
Source: Gut Microbes - April 15, 2024 Category: Microbiology Authors: Maria E. BarbianJoshua A. OwensCrystal R. NaudinPatricia DenningRavi M. PatelRheinallt M. Jonesa Department of Pediatrics, Emory University School of Medicine and Children ’s Healthcare of Atlanta, Atlanta, USAb Department of Biology, Lipscomb Universit Source Type: research

Pregnancy period and early-life risk factors for inflammatory bowel disease: a Northern Finland birth cohort 1966 study
The pathogenesis of inflammatory bowel disease (IBD) has not been fully elucidated. The aim of this study was to analyze the pregnancy period, perinatal period, and infancy period risk factors for IBD in a wel... (Source: BMC Public Health)
Source: BMC Public Health - April 15, 2024 Category: Consumer Health News Authors: Timo M. Blomster, Olli-Pekka Koivurova, Ritva Koskela, Karl-Heinz Herzig, Nicholas J. Talley and Jukka Ronkainen Tags: Research Source Type: research

Evaluation of the Patients with the Diagnosis of Pontocerebellar Hypoplasia: A Multicenter National Study
AbstractPontocerebellar hypoplasia (PCH) is a heterogeneous group of neurodegenerative disorders characterized by hypoplasia and degeneration of the cerebellum and pons. We aimed to identify the clinical, laboratory, and imaging findings of the patients with diagnosed PCH with confirmed genetic analysis. We collected available clinical data, laboratory, and imaging findings in our retrospective multicenter national study of 64 patients with PCH in Turkey. The genetic analysis included the whole-exome sequencing (WES), targeted next-generation sequencing (NGS), or single gene analysis. Sixty-four patients with PCH were 28 f...
Source: The Cerebellum - April 15, 2024 Category: Neurology Source Type: research

Characteristics Associated with Trial of Labor among Patients with Twin Pregnancies
Conclusion In this cohort of twin gestations with a high frequency of TOL, patient and provider characteristics are associated with attempting vaginal delivery. Variation in provider practices suggests differing skills and comfort with twin vaginal delivery may influence route of delivery decision-making in patients with twins. Keypoints [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - April 15, 2024 Category: Perinatology & Neonatology Authors: Cipres, Danielle T. Cowherd, Rachael B. Barry, Olivia H. Chen, Liqi Yee, Lynn M. Tags: SMFM Fellows Research Series Source Type: research

Is social media our new quitline? A descriptive study assessing youtube coverage of tobacco cessation
ConclusionsEnvironmental exposure presents significant risks for acute and chronic diseases for both smokers and nonsmokers, and specific risks for children and pregnant women, and this requires further investigation. Education for individuals, families and communities on tobacco cessation can help people achieve cessation. Social media such as YouTube promises to reach large audiences at low cost without requiring high reading literacy. Additional attention is needed to create videos with up-to-date, accurate information that can engage consumers. (Source: Journal of Preventive Medicine and Hygiene)
Source: Journal of Preventive Medicine and Hygiene - April 15, 2024 Category: International Medicine & Public Health Authors: Aysha Jawed, Anna Hogan Source Type: research

Knowledge, attitudes, and practices related to the prevention of adverse pregnancy outcomes among samples of females in Al ‐Suwaira city, Wasit Governorate, Iraq
Conclusions: The participants in this study had good knowledge, positive attitude, and positive practice regarding adverse pregnancy outcomes. However, there were some knowledge gaps. Therefore, to raise awareness among local women, it seems advisable to strengthen and strictly apply awareness-raising plans.  (Source: Journal of Preventive Medicine and Hygiene)
Source: Journal of Preventive Medicine and Hygiene - April 15, 2024 Category: International Medicine & Public Health Authors: Israa Dawood Salim, Manal Hadi Ghaffoori Kanaan, Ahmad M. Tarek, Sura Saad Abdullah Source Type: research

Maternal MTHFR A1298C Polymorphism: A Crucial Consideration in Preventing Recurrent Pregnancy Loss
Editorial (Source: Journal of Preventive Medicine and Hygiene)
Source: Journal of Preventive Medicine and Hygiene - April 15, 2024 Category: International Medicine & Public Health Authors: Sinu Jose Source Type: research