Microbiome reveals inflammatory ‐related bacteria and putative functional pathways involved in human papillomavirus‐associated penile squamous cell carcinoma
ConclusionWe describe the first microbiome of penile carcinoma, which revealed an abundant and diverse microbiota as well as inflammatory-related taxa (the phyla Proteobacteria and Firmicutes, the generaFusobacterium andPrevotella, and the speciesFinegoldia magma andPseudomonas geniculata) and molecular pathways (chitin derivates degradation, the protocatechuic acid pathway, inositol metabolism, and the sucrose pathway), which have also been linked to inflammation and carcinogenesis. Moreover, we found specific and abundant ASVs in both tumor and non-tumor tissues. Our data encourage further study to better understand the ...
Source: Andrology - October 16, 2023 Category: Urology & Nephrology Authors: Amanda de Deus,
Gabriele Gon çalves,
Jenilson da Silva,
Luís Cláudio de Jesus,
Ana Paula S. Azevedo‐Santos,
Hivana Dall Agnol,
Silma Regina Pereira Tags: ORIGINAL ARTICLE Source Type: research
Cancers, Vol. 15, Pages 4984: The Influence of the Microbiome on Urological Malignancies: A Systematic Review
vich
Hemendra N. Shah
The microbiome, once considered peripheral, is emerging as a relevant player in the intricate web of factors contributing to cancer development and progression. These often overlooked microorganisms, in the context of urological malignancies, have been investigated primarily focusing on the gut microbiome, while exploration of urogenital microorganisms remains limited. Considering this, our systematic review delves into the complex role of these understudied actors in various neoplastic conditions, including prostate, bladder, kidney, penile, and testicular cancers. Our analysis found a total of...
Source: Cancers - October 14, 2023 Category: Cancer & Oncology Authors: Joao G. Porto Maria Camila Suarez Arbelaez Brandon Pena Archan Khandekar Ankur Malpani Bruno Nahar Sanoj Punnen Chad R. Ritch Mark L. Gonzalgo Dipen J. Parekh Robert Marcovich Hemendra N. Shah Tags: Systematic Review Source Type: research
Testicular Cancer: The Unmet Needs of a Younger Generation of Cancer Survivors
Nurs Clin North Am. 2023 Dec;58(4):581-593. doi: 10.1016/j.cnur.2023.07.005. Epub 2023 Aug 17.ABSTRACTUnmet holistic needs of various cancer populations, with examples including prostate, bladder, gynecologic, kidney, penile, breast, and colorectal, along with holistic impacts of cancer on older adults, have been defined by a growing number of systematic reviews. Unfortunately, there continues to be a lack of clinical insight into the unique needs of younger men with testicular cancer. Survival rate based on low mortality rates and good prognosis if early detection and treatment implementation grows the number of men who n...
Source: Clinical Prostate Cancer - October 13, 2023 Category: Cancer & Oncology Authors: Blake K Smith Source Type: research
Testicular Cancer: The Unmet Needs of a Younger Generation of Cancer Survivors
Nurs Clin North Am. 2023 Dec;58(4):581-593. doi: 10.1016/j.cnur.2023.07.005. Epub 2023 Aug 17.ABSTRACTUnmet holistic needs of various cancer populations, with examples including prostate, bladder, gynecologic, kidney, penile, breast, and colorectal, along with holistic impacts of cancer on older adults, have been defined by a growing number of systematic reviews. Unfortunately, there continues to be a lack of clinical insight into the unique needs of younger men with testicular cancer. Survival rate based on low mortality rates and good prognosis if early detection and treatment implementation grows the number of men who n...
Source: Clinical Breast Cancer - October 13, 2023 Category: Cancer & Oncology Authors: Blake K Smith Source Type: research
Testicular Cancer: The Unmet Needs of a Younger Generation of Cancer Survivors
Nurs Clin North Am. 2023 Dec;58(4):581-593. doi: 10.1016/j.cnur.2023.07.005. Epub 2023 Aug 17.ABSTRACTUnmet holistic needs of various cancer populations, with examples including prostate, bladder, gynecologic, kidney, penile, breast, and colorectal, along with holistic impacts of cancer on older adults, have been defined by a growing number of systematic reviews. Unfortunately, there continues to be a lack of clinical insight into the unique needs of younger men with testicular cancer. Survival rate based on low mortality rates and good prognosis if early detection and treatment implementation grows the number of men who n...
Source: Clinical Genitourinary Cancer - October 13, 2023 Category: Cancer & Oncology Authors: Blake K Smith Source Type: research
Testicular Cancer: The Unmet Needs of a Younger Generation of Cancer Survivors
Nurs Clin North Am. 2023 Dec;58(4):581-593. doi: 10.1016/j.cnur.2023.07.005. Epub 2023 Aug 17.ABSTRACTUnmet holistic needs of various cancer populations, with examples including prostate, bladder, gynecologic, kidney, penile, breast, and colorectal, along with holistic impacts of cancer on older adults, have been defined by a growing number of systematic reviews. Unfortunately, there continues to be a lack of clinical insight into the unique needs of younger men with testicular cancer. Survival rate based on low mortality rates and good prognosis if early detection and treatment implementation grows the number of men who n...
Source: Clinical Colorectal Cancer - October 13, 2023 Category: Cancer & Oncology Authors: Blake K Smith Source Type: research
superinfected penile cancer complicated by genital gangrene: management and role of gangrene biopsy
A 70-year-old man was referred to the urology clinic because of Fournier's genital gangrene, the main reason for consultation in this elderly multitarre patient is the unpleasant odor felt by him (Figure 1). The patient was being followed for unbalanced diabetes and morbid obesity associated with these complications of maceration and prolonged bed rest. Initial urological evaluation revealed necrosis lesions at the base of the penis with pus discharge through, with a fixed right inguinal adenopathy, confirmed by CT scan (Figure 2). (Source: Urology)
Source: Urology - October 10, 2023 Category: Urology & Nephrology Authors: Hammou el farhaoui, Anouar Elmoudane, Debe Sallem, Mohammed Irzi, Ali Barki. Source Type: research
A population-based analysis of the epidemiology of penile cancer in Newfoundland and Labrador
CONCLUSIONS: The incidence of penile cancer in our population was higher than reported Western jurisdictions and showed frequent rates of metastatic spread. These observations are likely multifactorial, resultant of chronic inflammation paired with high rates of modifiable risk factors and diagnostic delays. An evident need for greater examination and improved reporting of these malignancies in the province was identified.PMID:37812793 | DOI:10.5489/cuaj.8451 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - October 9, 2023 Category: Urology & Nephrology Authors: W C Ian Janes Paul H Johnston Source Type: research
A population-based analysis of the epidemiology of penile cancer in Newfoundland and Labrador
CONCLUSIONS: The incidence of penile cancer in our population was higher than reported Western jurisdictions and showed frequent rates of metastatic spread. These observations are likely multifactorial, resultant of chronic inflammation paired with high rates of modifiable risk factors and diagnostic delays. An evident need for greater examination and improved reporting of these malignancies in the province was identified.PMID:37812793 | DOI:10.5489/cuaj.8451 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - October 9, 2023 Category: Urology & Nephrology Authors: W C Ian Janes Paul H Johnston Source Type: research
A population-based analysis of the epidemiology of penile cancer in Newfoundland and Labrador
CONCLUSIONS: The incidence of penile cancer in our population was higher than reported Western jurisdictions and showed frequent rates of metastatic spread. These observations are likely multifactorial, resultant of chronic inflammation paired with high rates of modifiable risk factors and diagnostic delays. An evident need for greater examination and improved reporting of these malignancies in the province was identified.PMID:37812793 | DOI:10.5489/cuaj.8451 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - October 9, 2023 Category: Urology & Nephrology Authors: W C Ian Janes Paul H Johnston Source Type: research
A population-based analysis of the epidemiology of penile cancer in Newfoundland and Labrador
CONCLUSIONS: The incidence of penile cancer in our population was higher than reported Western jurisdictions and showed frequent rates of metastatic spread. These observations are likely multifactorial, resultant of chronic inflammation paired with high rates of modifiable risk factors and diagnostic delays. An evident need for greater examination and improved reporting of these malignancies in the province was identified.PMID:37812793 | DOI:10.5489/cuaj.8451 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - October 9, 2023 Category: Urology & Nephrology Authors: W C Ian Janes Paul H Johnston Source Type: research
A population-based analysis of the epidemiology of penile cancer in Newfoundland and Labrador
CONCLUSIONS: The incidence of penile cancer in our population was higher than reported Western jurisdictions and showed frequent rates of metastatic spread. These observations are likely multifactorial, resultant of chronic inflammation paired with high rates of modifiable risk factors and diagnostic delays. An evident need for greater examination and improved reporting of these malignancies in the province was identified.PMID:37812793 | DOI:10.5489/cuaj.8451 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - October 9, 2023 Category: Urology & Nephrology Authors: W C Ian Janes Paul H Johnston Source Type: research
A population-based analysis of the epidemiology of penile cancer in Newfoundland and Labrador
CONCLUSIONS: The incidence of penile cancer in our population was higher than reported Western jurisdictions and showed frequent rates of metastatic spread. These observations are likely multifactorial, resultant of chronic inflammation paired with high rates of modifiable risk factors and diagnostic delays. An evident need for greater examination and improved reporting of these malignancies in the province was identified.PMID:37812793 | DOI:10.5489/cuaj.8451 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - October 9, 2023 Category: Urology & Nephrology Authors: W C Ian Janes Paul H Johnston Source Type: research
A population-based analysis of the epidemiology of penile cancer in Newfoundland and Labrador
CONCLUSIONS: The incidence of penile cancer in our population was higher than reported Western jurisdictions and showed frequent rates of metastatic spread. These observations are likely multifactorial, resultant of chronic inflammation paired with high rates of modifiable risk factors and diagnostic delays. An evident need for greater examination and improved reporting of these malignancies in the province was identified.PMID:37812793 | DOI:10.5489/cuaj.8451 (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - October 9, 2023 Category: Urology & Nephrology Authors: W C Ian Janes Paul H Johnston Source Type: research
Smoking is an independent risk factor for skin flap complications following inguinal lymph node dissection for penile cancer
Ir Med J. 2023 Sep 21;116(8):835.NO ABSTRACTPMID:37791702 (Source: Ir Med J)
Source: Ir Med J - October 4, 2023 Category: General Medicine Authors: M Muheilan A Sharif E MacCraith R Alhajahjeh D Power D Hennessey P Sweeney Source Type: research
