Compliance With NCCN Guidelines for Evaluation and Treatment of Anemia Among Patients With Solid Tumors
CONCLUSIONS: Anemia is common in patients with solid tumors; yet, compliance with NCCN Guidelines for evaluation and treatment of anemia remains low. There are opportunities to improve compliance with guidelines across the spectrum of cancer care.PMID:38489926 | DOI:10.6004/jnccn.2023.7108 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 15, 2024 Category: Cancer & Oncology Authors: Demetra Hypatia Hufnagel Lia Manfredi Bos Alaina Johnson Brown Lauren Shore Prescott Source Type: research
Cancers, Vol. 16, Pages 1066: Transcriptomic, Proteomic, and Genomic Mutational Fraction Differences Based on HPV Status Observed in Patient-Derived Xenograft Models of Penile Squamous Cell Carcinoma
z-Ferrer
Curtis A. Pettaway
Metastatic penile squamous cell carcinoma (PSCC) has only a 50% response rate to first-line combination chemotherapies and there are currently no targeted-therapy approaches. Therefore, we have an urgent need in advanced-PSCC treatment to find novel therapies. Approximately half of all PSCC cases are positive for high-risk human papillomavirus (HR-HPV). Our objective was to generate HPV-positive (HPV+) and HPV-negative (HPV−) patient-derived xenograft (PDX) models and to determine the biological differences between HPV+ and HPV− disease. We generated four HPV+ a...
Source: Cancers - March 6, 2024 Category: Cancer & Oncology Authors: Niki M. Zacharias Luis Segarra Keiko Akagi Natalie Wall Fowlkes Huiqin Chen Angelita Alaniz Carolyn de la Cerda Pedro Pesquera Yuanxin Xi Jing Wang Jad Chahoud Xin Lu Priya Rao Magaly Martinez-Ferrer Curtis A. Pettaway Tags: Article Source Type: research
Acute urinary retention due to corpus cavernosum penile metastasis from lung adenocarcinoma after targeted therapy: a case report and review of the literature
ConclusionThe penis may be a site of metastasis from primary lung cancer, especially for old patient. Metastasis to the penis usually indicates that the primary lung cancer is at an advanced stage and the prognosis is very poor. More research is necessary to understand the underlying mechanism of adenocarcinoma of lung metastasis. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - March 1, 2024 Category: Cancer & Oncology Source Type: research
Long-term outcomes of penile squamous cell carcinoma in men age 50 years old compared with men > 50 years old from a single tertiary referral centre: a propensity score matched analysis
Int J Impot Res. 2024 Feb 29. doi: 10.1038/s41443-024-00842-5. Online ahead of print.ABSTRACTPenile cancer (PeCa) is rare, and the oncological outcomes in younger men are unclear. We aimed to analyse and compare oncological outcomes of men age ≤50 years (y) and >50 years with PeCa. A retrospective analysis of men ≤50 y with penile squamous cell carcinoma managed at a tertiary centre was performed. A propensity score matched cohort of men >50 y was identified for comparison. Matching was according to tumour, nodal stage and the types of primary surgery. Overall survival (OS), disease-specific survival (DSS), recur...
Source: Cell Research - February 29, 2024 Category: Cytology Authors: Karl H Pang Giuseppe Fallara Morwarid Hemat Akash Ghosh Aiman Haider Alex Freeman Paul Hadway Raj Nigam Rowland Rees Anita Mitra Constantine Alifrangis Asif Muneer Hussain M Alnajjar Source Type: research
Long-term outcomes of penile squamous cell carcinoma in men age ≤50 years old compared with men >50 years old from a single tertiary referral centre: a propensity score matched analysis
International Journal of Impotence Research, Published online: 29 February 2024; doi:10.1038/s41443-024-00842-5Long-term outcomes of penile squamous cell carcinoma in men age ≤50 years old compared with men >50 years old from a single tertiary referral centre: a propensity score matched analysis (Source: International Journal of Impotence Research)
Source: International Journal of Impotence Research - February 29, 2024 Category: Urology & Nephrology Authors: Karl H. Pang Giuseppe Fallara Morwarid Hemat Akash Ghosh Aiman Haider Alex Freeman Paul Hadway Raj Nigam Rowland Rees Anita Mitra Constantine Alifrangis Asif Muneer Hussain M. Alnajjar Source Type: research
Robotic or open superficial inguinal lymph node dissection as staging procedures for clinically node negative high risk penile cancer
CONCLUSIONS: We observed similar complication rates and surgical variable outcomes in our analysis apart from operative time and operative drain duration. Oncological outcomes were similar between the two cohorts. RAIL was a reliable staging and potentially therapeutic procedure among clinically node negative patients with penile squamous cell carcinoma with comparable outcomes to an OSILND cohort.PMID:38388244 | DOI:10.1016/j.urolonc.2024.01.036 (Source: Urologic Oncology)
Source: Urologic Oncology - February 22, 2024 Category: Urology & Nephrology Authors: Manuel Ozambela Barrett Z McCormick Jan K Rudzinski Alberto C Pieretti Graciela M Nogueras Gonz ález Matthew A Meissner John N Papadopoulos Mehrad Adibi Surena F Matin Aaron S Dahmen Philippe E Spiess Curtis A Pettaway Source Type: research
Robotic or open superficial inguinal lymph node dissection as staging procedures for clinically node negative high risk penile cancer
CONCLUSIONS: We observed similar complication rates and surgical variable outcomes in our analysis apart from operative time and operative drain duration. Oncological outcomes were similar between the two cohorts. RAIL was a reliable staging and potentially therapeutic procedure among clinically node negative patients with penile squamous cell carcinoma with comparable outcomes to an OSILND cohort.PMID:38388244 | DOI:10.1016/j.urolonc.2024.01.036 (Source: Urologic Oncology)
Source: Urologic Oncology - February 22, 2024 Category: Urology & Nephrology Authors: Manuel Ozambela Barrett Z McCormick Jan K Rudzinski Alberto C Pieretti Graciela M Nogueras Gonz ález Matthew A Meissner John N Papadopoulos Mehrad Adibi Surena F Matin Aaron S Dahmen Philippe E Spiess Curtis A Pettaway Source Type: research
Robotic or open superficial inguinal lymph node dissection as staging procedures for clinically node negative high risk penile cancer
CONCLUSIONS: We observed similar complication rates and surgical variable outcomes in our analysis apart from operative time and operative drain duration. Oncological outcomes were similar between the two cohorts. RAIL was a reliable staging and potentially therapeutic procedure among clinically node negative patients with penile squamous cell carcinoma with comparable outcomes to an OSILND cohort.PMID:38388244 | DOI:10.1016/j.urolonc.2024.01.036 (Source: Urologic Oncology)
Source: Urologic Oncology - February 22, 2024 Category: Urology & Nephrology Authors: Manuel Ozambela Barrett Z McCormick Jan K Rudzinski Alberto C Pieretti Graciela M Nogueras Gonz ález Matthew A Meissner John N Papadopoulos Mehrad Adibi Surena F Matin Aaron S Dahmen Philippe E Spiess Curtis A Pettaway Source Type: research
Robotic or open superficial inguinal lymph node dissection as staging procedures for clinically node negative high risk penile cancer
CONCLUSIONS: We observed similar complication rates and surgical variable outcomes in our analysis apart from operative time and operative drain duration. Oncological outcomes were similar between the two cohorts. RAIL was a reliable staging and potentially therapeutic procedure among clinically node negative patients with penile squamous cell carcinoma with comparable outcomes to an OSILND cohort.PMID:38388244 | DOI:10.1016/j.urolonc.2024.01.036 (Source: Urologic Oncology)
Source: Urologic Oncology - February 22, 2024 Category: Urology & Nephrology Authors: Manuel Ozambela Barrett Z McCormick Jan K Rudzinski Alberto C Pieretti Graciela M Nogueras Gonz ález Matthew A Meissner John N Papadopoulos Mehrad Adibi Surena F Matin Aaron S Dahmen Philippe E Spiess Curtis A Pettaway Source Type: research
Human Papillomavirus Vaccination Coverage in Children Ages 9-17 Years: United States, 2022
This report uses parent-reported data from the 2022 National Health Interview Survey to describe the percentage of children ages 9-17 years who received at least one dose of the HPV vaccine by selected sociodemographic and health characteristics.PMID:38358336 (Source: NCHS data brief)
Source: NCHS data brief - February 15, 2024 Category: American Health Authors: Maria A Villarroel Adena M Galinsky Peng-Jun Lu Cassandra Pingali Source Type: research