Paternal peri ‐conceptional physical activity and the risk of congenital heart disease in offspring: A case–control study
This study aims to investigate the potential association between paternal pre-conceptional physical activity levels (PA), along with paternal peri-conceptional smoking and alcohol consumption, and the risk of CHD in offspring.Materials and methodsAn observational case –control study was conducted in Lebanon, with 279 participants, aiming to investigate potential risk factors for CHD. We included children with confirmed CHD, born between 2012 and 2022. Controls born in the same timeframe were selected randomly from the general population using online questionnai re forms. Mean age of children included was 6 years old (0...
Source: Andrology - April 12, 2024 Category: Urology & Nephrology Authors: Ornina Atieh,
Nohad Maria J. Azzi,
Georges J. Lteif,
Ninar A. Atieh,
Nadim Y. Germanos,
Val érie Grandjean,
Zalihe Yarkiner,
Zakhia Saliba,
Marie‐Claude Fadous Khalife,
Georges Raad Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
(Source: Andrology)
Source: Andrology - April 11, 2024 Category: Urology & Nephrology Tags: ISSUE INFORMATION Source Type: research
Excessive androgen exposure and risk of malignancies: A cohort study
Discussion and conclusionMale androgen users did not face an increased short-term risk of cancer, neither overall nor related to prostate or breast cancer. Our study indicates that the absolute risk of malignancies in androgen users is comparable to that in the background population. However, we cannot exclude androgens as a cancer risk factor due to the limited sample size, relatively short follow-up period, and subject age. (Source: Andrology)
Source: Andrology - April 11, 2024 Category: Urology & Nephrology Authors: Ida M. Heerfordt,
Josefine Windfeld ‐Mathiasen,
Kim Peder Dalhoff,
Jon Trærup Andersen,
Henrik Horwitz Tags: ORIGINAL ARTICLE Source Type: research
Prevalence of infertility and barriers to family building among male physicians
ConclusionOur results indicate a need for interventions to support family building and fertility evaluation and treatment among male physicians. (Source: Andrology)
Source: Andrology - April 10, 2024 Category: Urology & Nephrology Authors: Jasmine S. Lin,
Justin M. Dubin,
Jonathan Aguiar,
Robert E. Brannigan,
Joshua A. Halpern Tags: ORIGINAL ARTICLE Source Type: research
Knockout of phosphatidylethanolamine binding protein4 (PEBP4) promotes chronic non ‐bacterial prostatitis by mediating the activation of NF‐κB signaling
ConclusionThe knockout ofPEBP4 in experimental mice led to chronic prostatitis and the reduced expression of PEBP4 in patients with higher risk of chronic and non-bacterial prostatitis suggested that PEBP4 might act as a protective factor against chronic prostatitis. The knockout ofPEBP4 in RWPE-1 cells led to the increased activation of NF- κB and IκB, thus indicating that inhibition of PEBP4 faciliated the NF-κB signaling cascade. Our findings provide a new etiology and therapeutic target for chronic prostatitis. (Source: Andrology)
Source: Andrology - April 9, 2024 Category: Urology & Nephrology Authors: Hailan He,
Guancheng Xiao,
Xing Hu,
Hui Luo,
Yunfeng Liao,
Biao Qian,
Guoxi Zhang,
Xiaofeng Zou,
Junrong Zou Tags: ORIGINAL ARTICLE Source Type: research
PDE5is ‐naïve versus non‐naïve patients at first investigation for erectile dysfunction—findings from a long‐term, real‐life cross‐sectional study
ConclusionsSelf-prescription of PDE5is is an attitude presents in the general population, despite this phenomenon has decreased overtime. Current data outline the importance to keep promoting educational campaigns to promote PDE5is as effective and safe medicinal products, while avoiding their improper use. (Source: Andrology)
Source: Andrology - April 8, 2024 Category: Urology & Nephrology Authors: Simone Cilio,
Paolo Capogrosso,
Edoardo Pozzi,
Federico Belladelli,
Christian Corsini,
Massimiliano Raffo,
Luigi Candela,
Giuseppe Fallara,
Luca Boeri,
Alessia d'Arma,
Ciro Imbimbo,
Vincenzo Mirone,
Francesco Montorsi,
Andrea Salonia Tags: ORIGINAL ARTICLE Source Type: research
The human infertility single ‐cell testis atlas (HISTA): an interactive molecular scRNA‐Seq reference of the human testis
Discussion and conclusionsHISTA is a research environment that can help scientists organize and understand the high-dimensional transcriptional landscape of the human testis. HISTA has already contributed to published testis research and can be updated as needed with input from the research community or downloaded and modified for individual needs. (Source: Andrology)
Source: Andrology - April 6, 2024 Category: Urology & Nephrology Authors: Eisa Mahyari,
Katinka A. Vigh ‐Conrad,
Clément Daube,
Ana C. Lima,
Jingtao Guo,
Douglas T. Carrell,
James M. Hotaling,
Kenneth I. Aston,
Donald F. Conrad Tags: ORIGINAL ARTICLE Source Type: research
Phosphoproteomic analysis of the adaption of epididymal epithelial cells to corticosterone challenge
ConclusionsTogether, these data confirm that epididymal epithelial cells are reactive to corticosterone challenge, and that their response is tightly coupled to the opposing action of cellular kinases and phosphatases. (Source: Andrology)
Source: Andrology - April 5, 2024 Category: Urology & Nephrology Authors: David A. Skerrett ‐Byrne,
Simone J. Stanger,
Natalie A. Trigg,
Amanda L. Anderson,
Petra Sipilä,
Ilana R. Bernstein,
Tessa Lord,
John E. Schjenken,
Heather C. Murray,
Nicole M. Verrills,
Matthew D. Dun,
Terence Y. Pang,
Brett Nixon Tags: ORIGINAL ARTICLE Source Type: research
Trans men can achieve adequate muscular development through low ‐dose testosterone therapy: A long‐term study on body composition changes
ConclusionLong-term GAHT for trans men is safe and effective. Low-dose testosterone administration is sufficient to increase LBM in trans men. Higher testosterone doses can lead to an earlier increase in muscle mass. (Source: Andrology)
Source: Andrology - April 2, 2024 Category: Urology & Nephrology Authors: Yusuke Tominaga,
Tomoko Kobayashi,
Yuko Matsumoto,
Takatoshi Moriwake,
Yoshitaka Oshima,
Misa Okumura,
Satoshi Horii,
Takuya Sadahira,
Satoshi Katayama,
Takehiro Iwata,
Shingo Nishimura,
Kensuke Bekku,
Kohei Edamura,
Morito Sugimoto,
Yasuyuk Tags: ORIGINAL ARTICLE Source Type: research
Testicular sperm retrieval for intracytoplasmic sperm injection: when to consider it after unsuccessful intracytoplasmic sperm injection with ejaculated sperm?
ConclusionsTMS and DFI were found to be significant predictors of live birth outcomes in couples with oligozoospermic male partners undergoing T-ICSI. These findings may help clinicians tailor treatment strategies for this specific patient population. (Source: Andrology)
Source: Andrology - April 2, 2024 Category: Urology & Nephrology Authors: Muhammed Arif Ibis,
Eda Ureyen Ozdemir,
Khaled Obaid,
Cagri Akpinar,
Batuhan Ozmen,
Kaan Aydos,
Onder Yaman Tags: ORIGINAL ARTICLE Source Type: research
Which PDE5 inhibitor is the most effective in the treatment of erectile dysfunction in men with spinal cord injury? A systematic review and network meta ‐analysis
Discussion and conclusionWithin the grading of comparison network, tadalafil appeared to be the best PDE5i in the treatment of SCI-related ED. Further focused studies are warranted to confirm these findings and define optimal doses and duration of therapy. (Source: Andrology)
Source: Andrology - March 31, 2024 Category: Urology & Nephrology Authors: Daniele Tienforti,
Giorgio Felzani,
Alfonso Boris Di Pasquale,
Arcangelo Barbonetti Tags: ORIGINAL ARTICLE Source Type: research
Exploring sexual function in adrenal insufficiency: findings from the Dual RElease hydrocortisone versus conventionAl glucocorticoid replaceMent therapy in hypocortisolism (DREAM) trial
DiscussionSexual dysfunction is common in adrenal insufficiency patients and is likely explained by multiple factors. dual-release hydrocortisone treatment is not directly associated with sexual function improvement, but an indirect effect mediated by quality-of-life amelioration cannot be excluded. (Source: Andrology)
Source: Andrology - March 29, 2024 Category: Urology & Nephrology Authors: Valeria Hasenmajer,
Dario De Alcubierre,
Davide Ferrari,
Marianna Minnetti,
Ilaria Bonaventura,
Riccardo Pofi,
Chiara Simeoli,
Alessandra Tomaselli,
Francesca Sciarra,
Grazia Bottillo,
Francesco Angelini,
Alessia Cozzolino,
Mary Anna Venneri, Tags: ORIGINAL ARTICLE Source Type: research
Correlation between serum tryptophan metabolism and treatment efficacy of dapoxetine in patients with premature ejaculation: A pilot study
ConclusionsThis study demonstrates that the reduction in the TRP/LNAAs ratio and the elevation of the KYN/TRP ratio are significant characteristics associated with PPE. These findings suggest that diminished tryptophan availability in the brain and the activation of the kynurenine (KYN) pathway may play a role in the pathogenesis of PPE. The TRP/LNAAs ratio has potential as a reliable indicator of central serotonin (5-HT) levels. Considering the TRP/LNAAs ratio when selecting SSRIs for the treatment of PPE may enhance the response rate of this medication. (Source: Andrology)
Source: Andrology - March 22, 2024 Category: Urology & Nephrology Authors: Chenglun Wu,
Shengyu Huang,
Zhuojie Liu,
Yixin Wang,
Yuanqiang Zhu,
Zhi ‐Jun Zang Tags: ORIGINAL ARTICLE Source Type: research
Telomeric function and regulation during male meiosis in mice and humans
ConclusionsProper regulation of telomere activities is essential for male meiosis progression in mice and humans. (Source: Andrology)
Source: Andrology - March 21, 2024 Category: Urology & Nephrology Authors: Lisha Yin,
Nan Jiang,
Tao Li,
Youzhi Zhang,
Shuiqiao Yuan Tags: REVIEW ARTICLE Source Type: research
Erectile dysfunction criteria of 131,350 patients after open, laparoscopic, and robotic radical prostatectomy
ConclusionsThe reverse systematic review demonstrated that the robot-assisted radical prostatectomy showed higher rates of erectile function recovery at all times analyzed (1 –>18 months), in relation to the retropubic radical prostatectomy and laparoscopic radical prostatectomy. TheErection Sufficient for Intercourse criterion was the most used in the literature and showed the lowest bias capable of influencing the results and favoring any of the techniques and might be the fairest option for future comparisons. (Source: Andrology)
Source: Andrology - March 21, 2024 Category: Urology & Nephrology Authors: Tom ás Bernardo Costa Moretti,
Luís Alberto Magna,
Leonardo Oliveira Reis Tags: ORIGINAL ARTICLE Source Type: research
