An etiology-focused overview of vulvar and penile squamous cell carcinoma and its precursors: similarities, differences and emerging concepts
Although rare, cancer of the vulva and penis have significant morbidity, mortality, and potentially psychologically distressing treatments. At both sites, squamous cell carcinoma (SCC) is the most common tumor type. Transitioning from classification systems reliant on histomorphology, two pathways of carcinogenesis are recognized in genital SCC based on human papillomavirus (HPV) infection status: HPV-associated and HPV-independent. Each pathway has unique etiology, pathology, molecular findings, and prognostic differences with clinically relevant outcomes. (Source: Diagnostic Histopathology)
Source: Diagnostic Histopathology - November 11, 2023 Category: Pathology Authors: Michelle Schneider, Jennifer Crimmins, Angelica Selim Tags: Mini-symposium: skin pathology Source Type: research
Long-term follow-up of comparative study of open and endoscopic lymphadenectomy in patients with penile carcinoma
ConclusionsThe study shows that both open and endoscopic methods work well for controlling penile carcinoma in the long term. But the endoscopic approach is better because it has fewer severe complications. So, the choice of surgery method might depend on factors like the surgeon ’s experience, what they like, and what resources are available. (Source: Surgical Endoscopy)
Source: Surgical Endoscopy - November 10, 2023 Category: Surgery Source Type: research
Cancers, Vol. 15, Pages 5324: Multiparametric Magnetic Resonance Imaging of Penile Cancer: A Pictorial Review
Knut H. Hole
The role of multiparametric magnetic resonance imaging (mpMRI) in assessing penile cancer is not well defined. However, this modality may be successfully applied for preoperative staging and patient selection; postoperative local and regional surveillance; and assessments of treatment response after oncological therapies. Previous studies have been mostly limited to a few small series evaluating the accuracy of MRI for the preoperative staging of penile cancer. This review discusses the principles of non-erectile mpMRI, including functional techniques and their applications in evaluating the male genital r...
Source: Cancers - November 8, 2023 Category: Cancer & Oncology Authors: Marta D. Switlyk Andreas Hopland Edmund Reitan Shivanthe Sivanesan Bj ørn Brennhovd Ulrika Axcrona Knut H. Hole Tags: Review Source Type: research
Vaccines for HPV-associated diseases
Mol Aspects Med. 2023 Nov 4;94:101224. doi: 10.1016/j.mam.2023.101224. Online ahead of print.ABSTRACTHuman papillomavirus (HPV) infection represents a significant global health concern owing to its role in the etiology of conditions ranging from benign low-grade lesions to cancers of the cervix, head and neck, anus, vagina, vulva, and penis. Prophylactic vaccination programs, primarily targeting adolescent girls, have achieved dramatic reductions in rates of HPV infection and cervical cancer in recent years. However, there is a clear demand for a strategy to manage the needs of the many people who are already living with p...
Source: Molecular Medicine - November 6, 2023 Category: Molecular Biology Authors: Jeffrey M Skolnik Matthew P Morrow Source Type: research
Vaccines for HPV-associated diseases
Mol Aspects Med. 2023 Nov 4;94:101224. doi: 10.1016/j.mam.2023.101224. Online ahead of print.ABSTRACTHuman papillomavirus (HPV) infection represents a significant global health concern owing to its role in the etiology of conditions ranging from benign low-grade lesions to cancers of the cervix, head and neck, anus, vagina, vulva, and penis. Prophylactic vaccination programs, primarily targeting adolescent girls, have achieved dramatic reductions in rates of HPV infection and cervical cancer in recent years. However, there is a clear demand for a strategy to manage the needs of the many people who are already living with p...
Source: Molecular Medicine - November 6, 2023 Category: Molecular Biology Authors: Jeffrey M Skolnik Matthew P Morrow Source Type: research
Primary penile tuberculosis masquerading as penile cancer: a case report
Hong Kong Med J. 2023 Nov 2. doi: 10.12809/hkmj2210280. Online ahead of print.NO ABSTRACTPMID:37914671 | DOI:10.12809/hkmj2210280 (Source: Hong Kong Med J)
Source: Hong Kong Med J - November 1, 2023 Category: General Medicine Authors: A Sharma D Velmurugan K Narayanasamy Source Type: research
Expanding indications for urogenital transplantation: congenital and oncologic defects, and gender affirmation
Curr Opin Organ Transplant. 2023 Dec 1;28(6):425-430. doi: 10.1097/MOT.0000000000001111. Epub 2023 Sep 26.ABSTRACTPURPOSE OF REVIEW: Penile transplantation has become an emerging option for patients with severe genital defects. Only transplantation restores anatomy, sexual, and reproductive function of the penis. However, penile transplantation comes with important technical, psychosocial, ethical, and surgical challenges that must be considered for successful implementation. Indications for penile transplantation have yet to be clearly elucidated.RECENT FINDINGS: Since 2006, only five penile transplants have been performe...
Source: Current Opinion in Organ Transplantation - November 1, 2023 Category: Transplant Surgery Authors: Christopher D Lopez Alisa O Girard Richard J Redett Source Type: research
Primary penile tuberculosis masquerading as penile cancer: a case report
Hong Kong Med J. 2023 Nov 2. doi: 10.12809/hkmj2210280. Online ahead of print.NO ABSTRACTPMID:37914671 | DOI:10.12809/hkmj2210280 (Source: Hong Kong Med J)
Source: Hong Kong Med J - November 1, 2023 Category: General Medicine Authors: A Sharma D Velmurugan K Narayanasamy Source Type: research
Primary penile tuberculosis masquerading as penile cancer: a case report
Hong Kong Med J. 2023 Nov 2. doi: 10.12809/hkmj2210280. Online ahead of print.NO ABSTRACTPMID:37914671 | DOI:10.12809/hkmj2210280 (Source: Hong Kong Medical Journal)
Source: Hong Kong Medical Journal - November 1, 2023 Category: General Medicine Authors: A Sharma D Velmurugan K Narayanasamy Source Type: research
