Local infiltration analgesia in primary total knee arthroplasty.
CONCLUSIONS: Intra-operative single-dose LIA can effectively reduce postoperative pain, morphine demand, and morphine consumption. Therefore, the use of LIA is recommended during TKA. PMID: 31395787 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - August 5, 2019 Category: General Medicine Authors: Fang YY, Lee QJ, Chang EWY, Wong YC Tags: Hong Kong Med J Source Type: research

Prevalence of obstetric anal sphincter injury following vaginal delivery in primiparous women: a retrospective analysis.
CONCLUSIONS: Additional training for midwives and doctors may improve OASIS detection. PMID: 31395788 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - August 5, 2019 Category: General Medicine Authors: Kwok SPK, Wan OYK, Cheung RYK, Lee LL, Chung JPW, Chan SSC Tags: Hong Kong Med J Source Type: research

Common urological problems in children: primary nocturnal enuresis.
Abstract Enuresis is a common complaint in children, with a prevalence of around 15% at age 6 years. Evidence suggests that enuresis could affect neuropsychiatric development. The condition may represent an entire spectrum of underlying urological conditions. It is important to understand the difference between monosymptomatic and non-monosymptomatic enuresis. Primary monosymptomatic enuresis can be managed efficaciously with care in different settings, like primary care, specialist nursing, or paediatric specialists, while non-monosymptomatic enuresis requires more complex evaluation and treatment. The diagnosis,...
Source: Hong Kong Med J - August 5, 2019 Category: General Medicine Authors: Chan IHY, Wong KKY Tags: Hong Kong Med J Source Type: research

Parental consanguinity in Hong Kong.
CONCLUSIONS: It is essential that information on the increased risks associated with parental consanguinity is included in genetic counselling for consanguineous couples, so that they can make informed decisions. PMID: 31178441 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - June 10, 2019 Category: General Medicine Authors: Siong KH, Au Yeung SKC, Leung TY Tags: Hong Kong Med J Source Type: research

Peanut allergy and oral immunotherapy.
Abstract Peanut allergy is the commonest cause of food-induced anaphylaxis in the world, and it can be fatal. There have been many recent improvements to achieve safe methods of peanut desensitisation, one of which is to use a combination of anti-immunoglobulin E and oral immunotherapy. We have treated 27 patients with anti-immunoglobulin E and oral immunotherapy, and report on the outcomes and incidence of adverse reactions encountered during treatment. The dose of peanut protein tolerated increased from a median baseline of 5 to 2000 mg after desensitisation, which is substantially more than would be encountered...
Source: Hong Kong Med J - June 10, 2019 Category: General Medicine Authors: Lee TH, Chan JKC, Lau PC, Luk WP, Fung LH Tags: Hong Kong Med J Source Type: research

Hong Kong needs a territory-wide registry for out-of-hospital cardiac arrest.
Abstract Out-of-hospital cardiac arrest (OHCA) is an urgent disease entity, and the outcomes of OHCA are poor. This causes a significant public health burden, with loss of life and productivity throughout society. Internationally, successful programmes have adopted various survival enhancement measures to improve outcomes of OHCA. A territory-wide organised survival enhancement campaign is required in Hong Kong to maintain OHCA survival rates that are comparable to those of other large cities. One key component is to establish an OHCA registry, such as those in Asia, the United States, Europe, Australia, and New Z...
Source: Hong Kong Med J - June 10, 2019 Category: General Medicine Authors: Lui CT, Lau CL, Siu AYC, Fan KL, Leung LP Tags: Hong Kong Med J Source Type: research

Outcomes of transperineal and transrectal ultrasound-guided prostate biopsy.
CONCLUSION: For prostate biopsy, TPUSPB is safer, with no infection complications, and has similar prostate cancer detection rate compared with TRUSPB. PMID: 31178436 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - May 29, 2019 Category: General Medicine Authors: Lo KL, Chui KL, Leung CH, Ma SF, Lim K, Ng T, Wong J, Li JKM, Mak SK, Ng CF Tags: Hong Kong Med J Source Type: research

Faecal microbiota transplantation for treatment of recurrent or refractory Clostridioides difficile infection in Hong Kong.
CONCLUSION: Our results confirm that FMT is a safe, efficacious, and feasible intervention for patients with refractory or recurrent CDI in Hong Kong. Given the increasing disease burden and the lack of effective alternatives in Hong Kong for difficult-to-treat cases of CDI, we recommend that a territory-wide FMT service be established to address increasing demand for this treatment. PMID: 31178437 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - May 29, 2019 Category: General Medicine Authors: Lui RN, Wong SH, Lau LHS, Chan TT, Cheung KCY, Li AYL, Chin ML, Tang WWY, Ching JYL, Lam KLY, Chan PKS, Wu JCY, Sung JJY, Chan FKL, Ng SC Tags: Hong Kong Med J Source Type: research

Questionnaire survey on medical futility and termination of resuscitation in cardiac arrest patients among emergency physicians in Hong Kong.
CONCLUSION: Clinical practice and behaviour of TOR was not demonstrated to have associations with knowledge or attitude. Status as a Fellow of the Hong Kong College of Emergency Medicine or Advanced Cardiac Life Support instructor were the only two parameters identified that had significant relationships with earlier TOR in medically futile patients with OHCA. PMID: 31178438 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - May 29, 2019 Category: General Medicine Authors: So CW, Lui CT, Tsui KL, Chan KL, Law AKK, Wong YK, Li T, Wong CL, Leung SC Tags: Hong Kong Med J Source Type: research

Statins role in preventing contrast-induced acute kidney injury: a scoping review.
CONCLUSION: Statin therapy can be used as an adjunct to usual prophylactic measures such as adequate hydration and use of low-volume contrast media. Large well-designed trials on the effects of short-term high-dose statin use in preventing CI-AKI should be conducted, to eliminate any form of discrepancy among results, and to clarify any potential adverse effects. PMID: 31178439 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - May 29, 2019 Category: General Medicine Authors: Anjum I, Akmal M, Hasnain N, Jahangir M, Sohail W Tags: Hong Kong Med J Source Type: research

Budget impact of introducing tofacitinib to the public hospital formulary in Hong Kong, 2017-2021.
CONCLUSION: Introduction of tofacitinib to the formulary will provide 5-year savings, given the current drug price and patient volume. PMID: 31178440 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - May 29, 2019 Category: General Medicine Authors: Li X, Pathadka S, Man KK, Wong ICK, Chan EWY Tags: Hong Kong Med J Source Type: research

Infection control in residential care homes for the elderly in Hong Kong (2005-2014).
Abstract INTRODUCTION: This serial cross-sectional survey study aimed to review the trend in various infection control practices in residential care homes for the elderly (RCHEs) in Hong Kong from 2005 to 2014. METHODS: Annual cross-sectional surveys were conducted at all RCHEs in Hong Kong, including self-administered questionnaires, on-site interviews, inspections, and assessments conducted by trained nurses, from 2005 to 2014. In all, 98.5% to 100% of all RCHEs were surveyed each year based on the list of licensed RCHEs in Hong Kong. RESULTS: There was a substantial increase in the proportion of RCHE ...
Source: Hong Kong Med J - April 10, 2019 Category: General Medicine Authors: Wong GCY, Ng T, Li T Tags: Hong Kong Med J Source Type: research

Poisoning by toxic plants in Hong Kong: a 15-year review.
CONCLUSIONS: Although most plant exposure resulted in a self-limiting disease, severe poisonings were encountered. Epidemiology of plant poisonings is geographically specific. Clinicians should be aware of local poisonous plants and their toxicities. PMID: 30967518 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - April 10, 2019 Category: General Medicine Authors: Ng WY, Hung LY, Lam YH, Chan SS, Pang KS, Chong YK, Ching CK, Mak TWL Tags: Hong Kong Med J Source Type: research

Rubella (German measles) revisited.
Abstract Rubella is generally a mild and self-limited disease in children. During pregnancy, rubella can have potentially devastating effects on the developing fetus. Postnatal rubella is transmitted primarily by inhalation of virus-laden airborne droplets or direct contact with infected nasopharyngeal secretions. In susceptible pregnant women, the virus may cross the placenta and spread through the vascular system of the developing fetus. Postnatally acquired rubella typically begins with fever and lymphadenopathy, followed by an erythematous, maculopapular rash. The rash classically begins on the face, spreads c...
Source: Hong Kong Med J - April 10, 2019 Category: General Medicine Authors: Leung AKC, Hon KL, Leong KF Tags: Hong Kong Med J Source Type: research

Efficacy and safety of perioperative tranexamic acid in elderly patients undergoing trochanteric fracture surgery: a randomised controlled trial.
This study aimed to evaluate the efficacy and safety of a three-dose regimen of tranexamic acid on blood loss and transfusion rate in elderly patients with trochanteric fractures. METHODS: Eligible patients with trochanteric fractures surgically treated by dynamic hip screw and proximal anti-rotating intramedullary nail between March 2016 and October 2017 were enrolled in the study. Patients were randomly assigned to receive 15 mg/kg intravenous tranexamic acid dissolved in 100 mL of saline (TXA group) or 100 mL of saline solution (placebo group) over 10 minutes before, during, and after surgery. Perioperative blood l...
Source: Hong Kong Med J - March 28, 2019 Category: General Medicine Authors: Chen F, Jiang Z, Li M, Zhu X Tags: Hong Kong Med J Source Type: research

Non-surgical treatment of knee osteoarthritis.
Abstract Knee osteoarthritis is one of the most common degenerative diseases causing disability in elderly patients. Osteoarthritis is an increasing problem for ageing populations, such as that in Hong Kong. It is important for guidelines to be kept up to date with the best evidence-based osteoarthritis management practices available. The aim of this study was to review the current literature and international guidelines on non-surgical treatments for knee osteoarthritis and compared these with the current guidelines in Hong Kong, which were proposed in 2005. Internationally, exercise programmes for non-surgical m...
Source: Hong Kong Med J - March 28, 2019 Category: General Medicine Authors: Kan HS, Chan PK, Chiu KY, Yan CH, Yeung SS, Ng YL, Shiu KW, Ho T Tags: Hong Kong Med J Source Type: research

Enhanced recovery after surgery for liver resection.
CONCLUSIONS: The ERAS perioperative programme for liver resection is safe and feasible. It significantly shortened the hospital stay after open liver resection but not after laparoscopic liver resection. PMID: 30919808 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - March 27, 2019 Category: General Medicine Authors: Chong CC, Chung WY, Cheung YS, Fung AK, Fong AK, Lok HT, Wong J, Lee KF, Chan SK, Lai PB Tags: Hong Kong Med J Source Type: research

Editorial.
PMID: 30792362 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - February 1, 2019 Category: General Medicine Authors: Ma ES, Collins RA Tags: Hong Kong Med J Source Type: research

Extended early intervention versus standard psychiatric care for adults with first-episode psychosis.
PMID: 30792363 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - February 1, 2019 Category: General Medicine Authors: Chang WC, Chan SK, Lee EH, Hui CL, Chen EY Tags: Hong Kong Med J Source Type: research

Stepped care programme in primary care to prevent anxiety and depression: a randomised clinical trial.
PMID: 30792364 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - February 1, 2019 Category: General Medicine Authors: Wong SY, Tang WK, Mak WW, Cheung FM, Mercer S, Griffiths SM, Woo J, Lee DT, Kung K, Lam AT Tags: Hong Kong Med J Source Type: research

15-year computer-record study of adolescents exposed to peer suicide.
PMID: 30792365 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - February 1, 2019 Category: General Medicine Authors: Tang CP, Hung SF, Lee CC, Ho TP, Leung PW Tags: Hong Kong Med J Source Type: research

Adolescent alcohol drinking in Hong Kong: a school-based survey.
PMID: 30792366 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - February 1, 2019 Category: General Medicine Authors: Ho DS, Huang R, Wang MP, Lo WS, Lam TH Tags: Hong Kong Med J Source Type: research

Underage drinking motivation and contexts in Hong Kong: a qualitative analysis.
PMID: 30792367 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - February 1, 2019 Category: General Medicine Authors: Yoon S, Lam WW, Ho DS Tags: Hong Kong Med J Source Type: research

Associations of wheeze during the first 18 months of life with indoor nitrogen dioxide, formaldehyde, and family history of asthma: a prospective cohort study.
PMID: 30792368 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - February 1, 2019 Category: General Medicine Authors: Li AM, Fung CK, Yu IT, Goggins WB, Chan GY, Chan CK, Lau AP, Leung JO Tags: Hong Kong Med J Source Type: research

Respiratory health effects of household cleaning products on Hong Kong school children.
PMID: 30792369 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - February 1, 2019 Category: General Medicine Authors: Lao XQ, Ho KF, Wong CC, Tian LW Tags: Hong Kong Med J Source Type: research

Oral chloral hydrate versus intranasal dexmedetomidine for sedation of children undergoing computed tomography: a multicentre study.
PMID: 30792370 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - February 1, 2019 Category: General Medicine Authors: Yuen VM, Cheuk DK, Hui TW, Wong IC, Lam WW, Irwin MG Tags: Hong Kong Med J Source Type: research

Mirror therapy with bilateral arm training for hemiplegic upper extremity motor functions in patients with chronic stroke.
PMID: 30792371 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - February 1, 2019 Category: General Medicine Authors: Fong KN, Ting KH, Chan CC, Li LS Tags: Hong Kong Med J Source Type: research

Prenatal exposure to dioxins and subsequent neurocognitive and developmental function in Hong Kong Chinese children.
PMID: 30792372 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - February 1, 2019 Category: General Medicine Authors: Hui LL, Lam HS, Lau EY, Nelson EA, Wong TW, Fielding R Tags: Hong Kong Med J Source Type: research

Psychometric properties of Chinese version of Dementia Management Strategies Scale among family caregivers.
PMID: 30792373 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - February 1, 2019 Category: General Medicine Authors: Chien WT, Chan SW, Gray R, Yip LK Tags: Hong Kong Med J Source Type: research

Editorial.
PMID: 30674699 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - January 26, 2019 Category: General Medicine Authors: Ma ES, Collins RA Tags: Hong Kong Med J Source Type: research

Adherence therapy for schizophrenia: a randomised controlled trial.
PMID: 30674700 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - January 26, 2019 Category: General Medicine Authors: Chien WT, Cheung EF, Mui JH, Gray R, Ip G Tags: Hong Kong Med J Source Type: research

Duration of early intervention for psychosis: 2 years versus 3 years.
PMID: 30674701 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - January 26, 2019 Category: General Medicine Authors: Chen EY, Chang WC, Hui CL, Chan SK, Lee EH, Wong GH Tags: Hong Kong Med J Source Type: research

Mobile self-compassion programme for promotion of public mental health: a randomised controlled trial.
PMID: 30674702 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - January 26, 2019 Category: General Medicine Authors: Mak WW, Wong CC, Chan AT, Lau JT Tags: Hong Kong Med J Source Type: research

Consultation pattern of Hong Kong primary care attenders for psychological distress.
PMID: 30674703 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - January 26, 2019 Category: General Medicine Authors: Lam TP, Lo TL, Chao DV, Lam KF, Lam WW, Sun KS Tags: Hong Kong Med J Source Type: research

Co-occurrence of schizophrenia and smoking: a qualitative study.
PMID: 30674704 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - January 26, 2019 Category: General Medicine Authors: Mak YW, Loke AY, Chiang VC Tags: Hong Kong Med J Source Type: research

Combined electroacupuncture and auricular acupuncture for primary insomnia: a randomised controlled trial of dose-response effect.
PMID: 30674705 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - January 26, 2019 Category: General Medicine Authors: Chung KF, Yeung WF, Yu BY, Zhang SP, Zhang ZJ Tags: Hong Kong Med J Source Type: research

Relative contribution and interactive effects of psychological, social, and environmental correlates of physical activity, sedentary behaviour, and dietary behaviours in Hong Kong adolescents.
PMID: 30674706 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - January 26, 2019 Category: General Medicine Authors: Cerin E, Sit CH, Wong SH, Huang YJ, Gao GY, Lai PC, Macfarlane DJ, Barnett A Tags: Hong Kong Med J Source Type: research

Integrated adventure-based training and health education programme in promoting regular physical activity among childhood cancer survivors.
PMID: 30674707 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - January 26, 2019 Category: General Medicine Authors: Li WH, Chan GC, Lam MH, Chung JO, Chiu SY, Fong DY Tags: Hong Kong Med J Source Type: research

Biomechanical approach in facilitating long-distance walking of healthy elderly people.
PMID: 30674708 [PubMed - in process] (Source: Hong Kong Med J)
Source: Hong Kong Med J - January 26, 2019 Category: General Medicine Authors: Li WH, Lee WC, Leung AK, Zhang M Tags: Hong Kong Med J Source Type: research

Sudden arrhythmia death syndrome in young victims: a five-year retrospective review and two-year prospective molecular autopsy study by next-generation sequencing and clinical evaluation of their first-degree relatives.
CONCLUSION: This pilot feasibility study shows the value of incorporating cardiac evaluation of surviving relatives and next-generation sequencing molecular autopsy into conventional forensic investigations in diagnosing young SCD victims in East Asian populations. The interpretation of genetic variants in the context of SCD is complicated and we recommend its analysis and reporting by qualified pathologists. PMID: 30670673 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - January 23, 2019 Category: General Medicine Authors: Mak CM, Mok NS, Shum HC, Siu WK, Chong YK, Lee HH, Fong NC, Tong SF, Lee KW, Ching CK, Chen SP, Cheung WL, Tso CB, Poon WM, Lau CL, Lo YK, Tsui PT, Shum SF, Lee KC Tags: Hong Kong Med J Source Type: research

Totally laparoscopic versus open gastrectomy for advanced gastric cancer: a matched retrospective cohort study.
This study aimed to compare outcomes following laparoscopic versus open gastrectomy for advanced gastric cancer at a regional institution in Hong Kong. METHODS: Fifty-four patients who underwent laparoscopic gastrectomy from January 2009 to March 2017 were compared with 167 patients who underwent open gastrectomy during the same period. All had clinical T2 to T4 lesions and underwent curative-intent surgery. The two groups were matched for age, sex, American Society of Anaesthesiologists class, tumour location, morphology, and clinical stage. The endpoints were perioperative and long-term outcomes including survival a...
Source: Hong Kong Med J - January 18, 2019 Category: General Medicine Authors: Chan BY, Yau KK, Chan CK Tags: Hong Kong Med J Source Type: research

Survey on prevalence of lower urinary tract symptoms in an Asian population.
Abstract INTRODUCTION: Lower urinary tract symptoms (LUTS) have a strong effect on socio-economic and individual quality of life. The aim of the present study was to investigate the prevalence of LUTS in an Asian population. METHODS: A telephone survey of individuals aged ≥40 years and of Chinese ethnicity was conducted. The survey included basic demographics, medical and health history, drinking habits, International Prostate Symptom Score, overactive bladder symptom score, Patient Health Questionnaire (PHQ-9) score, and Short Form (SF)-12v2 score. RESULTS: From March to May 2017, 17 338 calls were m...
Source: Hong Kong Med J - January 18, 2019 Category: General Medicine Authors: Yee CH, Chan CK, Teoh JY, Chiu PK, Wong JH, Chan ES, Hou SS, Ng CF Tags: Hong Kong Med J Source Type: research

Prevalence of chromosomal abnormalities and 22q11.2 deletion in conotruncal and non-conotruncal antenatally diagnosed congenital heart diseases in a Chinese population.
Abstract INTRODUCTION: The aim of the present study was to calculate the prevalence of chromosomal abnormalities among antenatally diagnosed congenital heart diseases (CHDs), and the prevalence of 22q11.2 deletion in those with conotruncal CHDs versus isolated non-conotruncal CHDs. METHODS: All patients with antenatal ultrasound finding of fetal CHDs in two obstetric units in a 5-year period were retrospectively reviewed. Detected CHDs were classified as conotruncal if the malformation involved either the aortic outflow tract or the pulmonary outflow tract; otherwise they were classified as non-conotruncal. K...
Source: Hong Kong Med J - January 18, 2019 Category: General Medicine Authors: Kong CW, Cheng YK, To WW, Leung TY Tags: Hong Kong Med J Source Type: research

Update on the Hong Kong Reference Framework for Hypertension Care for Adults in Primary Care Settings-review of evidence on the definition of high blood pressure and goal of therapy.
Abstract The Hong Kong Reference Framework for Hypertension Care for Adults in Primary Care Settings is updated regularly to ensure it reflects the latest medical development and best practice. In 2017, guidelines from the United States included a major change, adopting the lower blood pressure values of 130/80 mm Hg in defining hypertension, in contrast to the prevailing international consensus of 140/90 mm Hg. After thorough review of the literature and international guidelines, the Advisory Group on Hong Kong Reference Framework for Care of Diabetes and Hypertension in Primary Care Settings (Advisory Group) rec...
Source: Hong Kong Med J - January 3, 2019 Category: General Medicine Authors: Lim MK, Ha SCN, Luk KH, Yip WK, Tsang CSH, Wong MCS Tags: Hong Kong Med J Source Type: research

Title.
Abstract The Hong Kong Reference Framework for Hypertension Care for Adults in Primary Care Settings is updated regularly to ensure it reflects the latest medical development and best practice. In 2017, guidelines from the United States included a major change, adopting the lower blood pressure values of 130/80 mm Hg in defining hypertension, in contrast to the prevailing international consensus of 140/90 mm Hg. After thorough review of the literature and international guidelines, the Advisory Group on Hong Kong Reference Framework for Care of Diabetes and Hypertension in Primary Care Settings (Advisory Group) rec...
Source: Hong Kong Med J - January 3, 2019 Category: General Medicine Authors: Lim MK, Ha SC, Luk KH, Yip WK, Tsang CS, Wong MC Tags: Hong Kong Med J Source Type: research

Epidemiology of myopia and prevention of myopia progression in children in East Asia: a review.
CONCLUSION: Although various methods are effective for controlling myopia progression in children, no curative remedy exists for myopia. Health care professionals should be aware of the available methods, as well as their risks and benefits. Treatment should be individualised and based on the preferences of the patient's family, after full discussion of the risks and benefits of each modality. PMID: 30530867 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - December 3, 2018 Category: General Medicine Authors: Mak CY, Yam JC, Chen LJ, Lee SM, Young AL Tags: Hong Kong Med J Source Type: research

Clinical and genetic profile of congenital long QT syndrome in Hong Kong: a 20-year experience in paediatrics.
CONCLUSION: Identification of the disorder, administration of beta blockers, and lifestyle modification can prevent subsequent cardiac events in LQTS. Genotyping in patients with LQTS is essential in guiding medical therapy and improving prognosis. PMID: 30530868 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - December 3, 2018 Category: General Medicine Authors: Kwok SY, Liu AP, Chan CY, Lun KS, Fung JL, Mak CC, Chung BH, Yung TC Tags: Hong Kong Med J Source Type: research

Branded versus generic drug use in chronic disease management in Hong Kong-perspectives of health care professionals and the general public.
CONCLUSION: The knowledge and perception of generic substitution remains low, both in the general public and among health care professionals. This knowledge deficit could potentially lead to different perspectives among stakeholders regarding generic substitution. PMID: 30530869 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - December 3, 2018 Category: General Medicine Authors: Lee VW, Cheng FW, Fong FY, Ng EE, Lo LL, Ngai LY, Lam AS Tags: Hong Kong Med J Source Type: research

Cross-sectional study on emergency department management of sepsis.
CONCLUSION: There are considerable variations in sepsis care among EDs in Hong Kong. More training, resources, and research efforts should be directed to early ED sepsis care, to improve patient outcomes. PMID: 30429360 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - November 14, 2018 Category: General Medicine Authors: Hung KK, Lam RP, Lo RS, Tenney JW, Yang ML, Tai MC, Graham CA Tags: Hong Kong Med J Source Type: research

Validation and modification of the Ottawa subarachnoid haemorrhage rule in risk stratification of Asian Chinese patients with acute headache.
CONCLUSIONS: The Ottawa SAH rule demonstrated high sensitivity. Addition of vomiting and SBP>160 mm Hg to the Ottawa SAH rule may increase its sensitivity. PMID: 30416104 [PubMed - as supplied by publisher] (Source: Hong Kong Med J)
Source: Hong Kong Med J - November 9, 2018 Category: General Medicine Authors: Cheung HY, Lui CT, Tsui KL Tags: Hong Kong Med J Source Type: research