MIR-376A-2-5P as a potential prognostic marker for advanced penile squamous cell carcinomas trough HPV-dependent pathways
Am J Cancer Res. 2023 Nov 15;13(11):5466-5481. eCollection 2023.ABSTRACTPenile cancer (PeCa) is a rare tumor, generally associated with socioeconomic conditions in low-income countries. Hence, a delay in diagnosis and treatment leads in more advanced tumors, to higher comorbidity, and mortality. Human papillomavirus (HPV) infection has been identified as one of the major risk factors for PeCa. In addition, viral integration sites have been related to copy number alterations, impacting miRNAs/mRNA interactions and, consequently, the molecular pathways related to them. Nonetheless, studies on differentially expressed miRNAs ...
Source: Cell Research - December 7, 2023 Category: Cytology Authors: Jenilson M Silva Amanda J Deus Andr é A M Vale Ana Paula S Azevedo-Santos Leudivan Nogueira Ana C Laus Luciane Sussuchi Rui M Reis Alexander Birbrair Andr é S Khayat Silma Regina Pereira Source Type: research
Extramammary Paget's Disease of the Glans Penis Secondary to a Recurrent Urothelial Carcinoma of the Bladder
Ann Dermatol. 2023 Nov;35(Suppl 2):S369-S370. doi: 10.5021/ad.21.133.NO ABSTRACTPMID:38061748 | DOI:10.5021/ad.21.133 (Source: Annals of Dermatology)
Source: Annals of Dermatology - December 7, 2023 Category: Dermatology Authors: Gyoo Huh Bo-Bin Cha Heun Joo Lee Young-Jun Choi Won-Serk Kim Ga-Young Lee Source Type: research
Pathologically Confirmed Subcutaneous Fat and Lymphovascular Invasion of a Hypopigmented Area in Extramammary Paget Disease
We report a case of a 62-year-old male with EMPD that invaded the subcutaneous fat layer. He presented with a several-year history of a slowly expanding erythematous plaque with the hypopigmented area on the left penoscrotum. One month before presentation, the patient had undergone punch biopsy at another hospital and diagnosed with EMPD. He had no personal history of urogenital cancers. The patient was treated with Mohs micrographic surgery, and negative margins were achieved after four stages. The histopathologic findings revealed Paget cells scattered throughout the epidermis. At the hypopigmented area, Paget cells exte...
Source: Annals of Dermatology - December 7, 2023 Category: Dermatology Authors: Gyoo Huh Ga-Young Lee Yumin Chung Seung-Wan Chae Young-Jun Choi Source Type: research
Extramammary Paget's Disease of the Glans Penis Secondary to a Recurrent Urothelial Carcinoma of the Bladder
Ann Dermatol. 2023 Nov;35(Suppl 2):S369-S370. doi: 10.5021/ad.21.133.NO ABSTRACTPMID:38061748 | DOI:10.5021/ad.21.133 (Source: Annals of Dermatology)
Source: Annals of Dermatology - December 7, 2023 Category: Dermatology Authors: Gyoo Huh Bo-Bin Cha Heun Joo Lee Young-Jun Choi Won-Serk Kim Ga-Young Lee Source Type: research
Pathologically Confirmed Subcutaneous Fat and Lymphovascular Invasion of a Hypopigmented Area in Extramammary Paget Disease
We report a case of a 62-year-old male with EMPD that invaded the subcutaneous fat layer. He presented with a several-year history of a slowly expanding erythematous plaque with the hypopigmented area on the left penoscrotum. One month before presentation, the patient had undergone punch biopsy at another hospital and diagnosed with EMPD. He had no personal history of urogenital cancers. The patient was treated with Mohs micrographic surgery, and negative margins were achieved after four stages. The histopathologic findings revealed Paget cells scattered throughout the epidermis. At the hypopigmented area, Paget cells exte...
Source: Annals of Dermatology - December 7, 2023 Category: Dermatology Authors: Gyoo Huh Ga-Young Lee Yumin Chung Seung-Wan Chae Young-Jun Choi Source Type: research
Extramammary Paget's Disease of the Glans Penis Secondary to a Recurrent Urothelial Carcinoma of the Bladder
Ann Dermatol. 2023 Nov;35(Suppl 2):S369-S370. doi: 10.5021/ad.21.133.NO ABSTRACTPMID:38061748 | DOI:10.5021/ad.21.133 (Source: Annals of Dermatology)
Source: Annals of Dermatology - December 7, 2023 Category: Dermatology Authors: Gyoo Huh Bo-Bin Cha Heun Joo Lee Young-Jun Choi Won-Serk Kim Ga-Young Lee Source Type: research
Pathologically Confirmed Subcutaneous Fat and Lymphovascular Invasion of a Hypopigmented Area in Extramammary Paget Disease
We report a case of a 62-year-old male with EMPD that invaded the subcutaneous fat layer. He presented with a several-year history of a slowly expanding erythematous plaque with the hypopigmented area on the left penoscrotum. One month before presentation, the patient had undergone punch biopsy at another hospital and diagnosed with EMPD. He had no personal history of urogenital cancers. The patient was treated with Mohs micrographic surgery, and negative margins were achieved after four stages. The histopathologic findings revealed Paget cells scattered throughout the epidermis. At the hypopigmented area, Paget cells exte...
Source: Annals of Dermatology - December 7, 2023 Category: Dermatology Authors: Gyoo Huh Ga-Young Lee Yumin Chung Seung-Wan Chae Young-Jun Choi Source Type: research
Extramammary Paget's Disease of the Glans Penis Secondary to a Recurrent Urothelial Carcinoma of the Bladder
Ann Dermatol. 2023 Nov;35(Suppl 2):S369-S370. doi: 10.5021/ad.21.133.NO ABSTRACTPMID:38061748 | DOI:10.5021/ad.21.133 (Source: Annals of Dermatology)
Source: Annals of Dermatology - December 7, 2023 Category: Dermatology Authors: Gyoo Huh Bo-Bin Cha Heun Joo Lee Young-Jun Choi Won-Serk Kim Ga-Young Lee Source Type: research
Pathologically Confirmed Subcutaneous Fat and Lymphovascular Invasion of a Hypopigmented Area in Extramammary Paget Disease
We report a case of a 62-year-old male with EMPD that invaded the subcutaneous fat layer. He presented with a several-year history of a slowly expanding erythematous plaque with the hypopigmented area on the left penoscrotum. One month before presentation, the patient had undergone punch biopsy at another hospital and diagnosed with EMPD. He had no personal history of urogenital cancers. The patient was treated with Mohs micrographic surgery, and negative margins were achieved after four stages. The histopathologic findings revealed Paget cells scattered throughout the epidermis. At the hypopigmented area, Paget cells exte...
Source: Annals of Dermatology - December 7, 2023 Category: Dermatology Authors: Gyoo Huh Ga-Young Lee Yumin Chung Seung-Wan Chae Young-Jun Choi Source Type: research
Extramammary Paget's Disease of the Glans Penis Secondary to a Recurrent Urothelial Carcinoma of the Bladder
Ann Dermatol. 2023 Nov;35(Suppl 2):S369-S370. doi: 10.5021/ad.21.133.NO ABSTRACTPMID:38061748 | DOI:10.5021/ad.21.133 (Source: Annals of Dermatology)
Source: Annals of Dermatology - December 7, 2023 Category: Dermatology Authors: Gyoo Huh Bo-Bin Cha Heun Joo Lee Young-Jun Choi Won-Serk Kim Ga-Young Lee Source Type: research
Correlation between second and first primary cancer: systematic review and meta-analysis of 9 million cancer patients
CONCLUSIONS: This study recommends close clinical follow-up, monitoring and appropriate interventions in patients with relevant FPCs for better screening and early diagnosis of SPCs.PMID:38055899 | DOI:10.1093/bjs/znad377 (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - December 6, 2023 Category: Surgery Authors: Xinyu Wang Meiyuan Zeng Xueming Ju Anqi Lin Chaozheng Zhou Junyi Shen Zaoqu Liu Bufu Tang Quan Cheng Youyu Wang Jian Zhang Peng Luo Source Type: research
A targeted, personalized management strategy in advanced penile squamous cell carcinoma
We present a case of advanced PSCC utilizing multimodal management informed by next generation sequencing and circulating tumor DNA monitoring. (Source: Urology)
Source: Urology - December 4, 2023 Category: Urology & Nephrology Authors: Levi C Holland, Thomas S Gerald, Bailey Brooks, Vitaly Margulis Source Type: research
EE286 Cost Effectiveness and Public Health Impact of Implementing Gender-Neutral Vaccination with the 9-Valent Human Papillomavirus Vaccine in Turkiye
This study will assess the cost effectiveness and health impact of inclusion of Gender-Neutral Vaccination (GNV) with 9-Valent HPV (9vHPV) in NIP in Turkiye for individuals aged 11-12 years old. (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: B. Akyol Ersoy, E. Ko ç, A. Pavelyev, V. Daniels, D. Ugrekhelidze, S. Malhan, M. Basaran, E. Ozyar, G. Hafiz, P.F. Yumuk, U. Selek, T. Yalti, T. Esen, C. Taskiran, M. Gultekin, M.F. Kose, N. Ozgul Source Type: research
Human Papillomavirus (HPV)-Associated Cancers Among Hispanic Males in the United States: Late-Stage Diagnosis by Country of Origin
CONCLUSION: Certain subgroups of Hispanic males have higher odds of late-stage HPV-associated cancer diagnosis based on country of origin and insurance status. These findings call for improved efforts to increase HPV vaccination, particularly among these subgroups of Hispanic males. Efforts to improve health care access and early detection from health care providers are also needed.PMID:38015627 | DOI:10.1177/10732748231218088 (Source: Cancer Control)
Source: Cancer Control - November 28, 2023 Category: Cancer & Oncology Authors: Seiichi Villalona Satsuki Villalona Daisy Reinoso Simone Sukhdeo Antoinette M Stroup Jeanne M Ferrante Source Type: research
Differences in overall survival of penile cancer patients versus population-based controls
CONCLUSION: SCCP patients exhibit worse OS across all stages. The difference in OS at 5 years between SCCP and age-matched male population-based controls ranged from 17% to 61%. At 5 years, CSM accounted for 12% to 60% of all deaths, across all stages.PMID:38014575 | DOI:10.1111/iju.15346 (Source: Cancer Control)
Source: Cancer Control - November 28, 2023 Category: Cancer & Oncology Authors: Lukas Scheipner Stefano Tappero Mattia Luca Piccinelli Francesco Barletta Cristina Cano Garcia Reha-Baris Incesu Simone Morra Zhe Tian Fred Saad Shahrokh F Shariat Carlo Terrone Ottavio De Cobelli Alberto Briganti Felix K H Chun Derya Tilki Nicola Longo M Source Type: research
