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Do intra-abdominal adhesions cause pain?
PMID: 29265400 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - December 22, 2017 Category: Surgery Authors: MacFie J Tags: Br J Surg Source Type: research

Cost-effective surgery for better outcomes.
PMID: 29265401 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - December 22, 2017 Category: Surgery Authors: Paterson-Brown S Tags: Br J Surg Source Type: research

The art of surgery.
Authors: PMID: 29265402 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - December 22, 2017 Category: Surgery Tags: Br J Surg Source Type: research

Randomized clinical trial of duct-to-mucosa versus invagination pancreaticojejunostomy after pancreatoduodenectomy.
CONCLUSION: This study did not demonstrate a superiority of invagination over duct-to-mucosa pancreaticojejunostomy in the risk of POPF. However, in high-risk patients with a soft pancreas, invagination may reduce the risk of clinically relevant POPF compared with duct-to-mucosa. Registration number: UMIN000005890 (http://www.umin.ac.jp). PMID: 29265404 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - December 22, 2017 Category: Surgery Authors: Senda Y, Shimizu Y, Natsume S, Ito S, Komori K, Abe T, Matsuo K, Sano T Tags: Br J Surg Source Type: research

Lessons learned about prevalence and growth rates of abdominal aortic aneurysms from a 25-year ultrasound population screening programme.
CONCLUSION: The prevalence of screen-detected small and medium AAAs has decreased over the past 25 years, but growth rates have remained similar. Men with a subaneurysmal aorta at age 65 years have a substantial risk of developing a large AAA by the age of 80 years. PMID: 29265406 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - December 22, 2017 Category: Surgery Authors: Oliver-Williams C, Sweeting MJ, Turton G, Parkin D, Cooper D, Rodd C, Thompson SG, Earnshaw JJ, Gloucestershire and Swindon Abdominal Aortic Aneurysm Screening Programme Tags: Br J Surg Source Type: research

Systematic review and network meta-analysis of methods of mesh fixation during laparoscopic ventral hernia repair.
CONCLUSION: Both crude recurrence rates and the network meta-analysis favoured fixation with sutures during laparoscopic ventral hernia repair. PMID: 29227530 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - December 11, 2017 Category: Surgery Authors: Baker JJ, Öberg S, Andresen K, Klausen TW, Rosenberg J Tags: Br J Surg Source Type: research

Normothermic machine perfusion for the assessment and transplantation of declined human kidneys from donation after circulatory death donors.
CONCLUSION: NMP technology can be used to increase the number of DCD kidney transplants by assessing their quality before transplantation. PMID: 29210064 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - December 6, 2017 Category: Surgery Authors: Hosgood SA, Thompson E, Moore T, Wilson CH, Nicholson ML Tags: Br J Surg Source Type: research

Meta-analysis of the procedural risks of carotid endarterectomy and carotid artery stenting over time.
Abstract BACKGROUND: Stroke/death rates within 30 days of carotid endarterectomy (CEA) and carotid artery stenting (CAS) in RCTs inform current clinical guidelines. However, the risks may have changed in recent years with wider use of effective stroke prevention therapies, especially statins, improved patient selection and growing operator expertise. The aim of this study was to investigate whether the procedural stroke/death risks from CEA and CAS have changed over time. METHODS: MEDLINE and Embase were searched systematically from inception to May 2016 for observational cohort studies of CEA and CAS. Studie...
Source: The British Journal of Surgery - December 4, 2017 Category: Surgery Authors: Lokuge K, de Waard DD, Halliday A, Gray A, Bulbulia R, Mihaylova B Tags: Br J Surg Source Type: research

Comparison of gaze behaviour of trainee and experienced surgeons during laparoscopic gastric bypass.
Abstract BACKGROUND: Eye tracking presents a novel tool that could be used to profile skill levels in surgery objectively. The primary aim of this study was to identify differences in gaze behaviour between expert and junior surgeons performing a laparoscopic Roux-en-Y gastric bypass (LRYGB) for obesity. METHODS: This prospective observational study used a lightweight eye-tracking apparatus to determine the difference in gaze behaviours between expert (more than 75 procedures) and junior (75 or fewer procedures) surgeons at defined stages of LRYGB. Primary endpoints were normalized dwell time and fixation fre...
Source: The British Journal of Surgery - November 28, 2017 Category: Surgery Authors: Erridge S, Ashraf H, Purkayastha S, Darzi A, Sodergren MH Tags: Br J Surg Source Type: research

Early versus late recurrence of intrahepatic cholangiocarcinoma after resection with curative intent.
The objective of this study was to investigate the characteristics, treatment and prognosis of early versus late recurrence of intrahepatic cholangiocarcinoma (ICC) after hepatic resection. METHODS: Patients who underwent resection with curative intent for ICC were identified from a multi-institutional database. Data on clinicopathological characteristics, initial operative details, timing and sites of recurrence, recurrence management and long-term outcomes were analysed. RESULTS: A total of 933 patients were included. With a median follow-up of 22 months, 685 patients (73·4 per cent) experienced r...
Source: The British Journal of Surgery - November 28, 2017 Category: Surgery Authors: Zhang XF, Beal EW, Bagante F, Chakedis J, Weiss M, Popescu I, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Itaru E, Pawlik TM Tags: Br J Surg Source Type: research

Experimental study of delivery of humidified-warm carbon dioxide during open abdominal surgery.
CONCLUSION: HWCO2 diffusion into the abdomen in the context of open surgery afforded tissue protection and accelerated tissue repair in mice, while preserving normothermia. Surgical relevance Damage to the peritoneum always occurs during open abdominal surgery, by exposure to desiccating air and by mechanical trauma/damage owing to the surgical intervention. Previous experimental studies showed that humidified-warm carbon dioxide (HWCO2 ) reduced peritoneal damage during laparoscopic insufflation. Additionally, this intervention decreased experimental peritoneal carcinomatosis compared with the use of conventional dry-cold...
Source: The British Journal of Surgery - November 28, 2017 Category: Surgery Authors: Carpinteri S, Sampurno S, Malaterre J, Millen R, Dean M, Kong J, Chittleborough T, Heriot A, Lynch AC, Ramsay RG Tags: Br J Surg Source Type: research

Preliminary results of a cohort study of induction chemotherapy-based treatment for locally recurrent rectal cancer.
CONCLUSION: The incorporation of ICT in neoadjuvant regimens for locally recurrent rectal cancer is a promising strategy. PMID: 29168556 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - November 23, 2017 Category: Surgery Authors: van Zoggel DMGI, Bosman SJ, Kusters M, Nieuwenhuijzen GAP, Cnossen JS, Creemers GJ, van Lijnschoten G, Rutten HJT Tags: Br J Surg Source Type: research

Growth rates of pulmonary metastases after liver transplantation for unresectable colorectal liver metastases.
CONCLUSION: Patients treated by LT for unresectable CLM have a good prognosis following resection of pulmonary metastases. Doubling time did not appear to be worse with the immunosuppression used after LT. PMID: 29168565 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - November 23, 2017 Category: Surgery Authors: Grut H, Solberg S, Seierstad T, Revheim ME, Egge TS, Larsen SG, Line PD, Dueland S Tags: Br J Surg Source Type: research

Quality of life in a randomized trial of early closure of temporary ileostomy after rectal resection for cancer (EASY trial).
CONCLUSION: Although the randomized study found that early closure of the temporary ileostomy was associated with significantly fewer complications, this clinical advantage had no effect on the patients' HRQOL. Registration number: NCT01287637 (https://www.clinicaltrials.gov). PMID: 29168881 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - November 23, 2017 Category: Surgery Authors: Park J, Danielsen AK, Angenete E, Bock D, Marinez AC, Haglind E, Jansen JE, Skullman S, Wedin A, Rosenberg J Tags: Br J Surg Source Type: research

Impact of weight loss and eating difficulties on health-related quality of life up to 10  years after oesophagectomy for cancer.
CONCLUSION: Eating difficulties are associated with deterioration in several aspects of HRQoL up to 10 years after surgery for oesophageal cancer. PMID: 29160918 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - November 21, 2017 Category: Surgery Authors: Anandavadivelan P, Wikman A, Johar A, Lagergren P Tags: Br J Surg Source Type: research

Influence of national centralization of oesophagogastric cancer on management and clinical outcome from emergency upper gastrointestinal conditions.
CONCLUSION: Centralization of low incidence conditions such as oesophageal perforation to high-volume cancer centres provides a greater level of expertise and ultimately reduces mortality. PMID: 29155448 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - November 20, 2017 Category: Surgery Authors: Markar SR, Mackenzie H, Wiggins T, Askari A, Karthikesalingam A, Faiz O, Griffin SM, Birkmeyer JD, Hanna GB Tags: Br J Surg Source Type: research

Upregulation of epidermal gap junctional proteins in patients with venous disease.
CONCLUSION: Connexins were overexpressed in patients with simple varicose veins, with a stepwise increased expression through venous eczema to ulceration. Connexin 43 is a potential biomarker for venous disease. This finding suggests that varicose veins predispose skin to poor wound healing. Surgical relevance The overexpression of connexins, a family of gap junctional proteins, is known to cause poor healing in venous leg ulceration. It is not known whether there is any association with superficial venous disease. Here, connexin proteins were overexpressed in patients with uncomplicated varicose veins, before histological...
Source: The British Journal of Surgery - November 16, 2017 Category: Surgery Authors: Kanapathy M, Simpson R, Madden L, Thrasivoulou C, Mosahebi A, Becker DL, Richards T Tags: Br J Surg Source Type: research

Patient-reported rates of chronic pain and recurrence after groin hernia repair.
CONCLUSION: The risk of significant pain 1 year after groin hernia repair in routine surgical practice was 15·2 per cent. This figure was lower in patients who had surgery by an endoscopic technique, but at the price of a significantly higher risk of reoperation for recurrence. PMID: 29139566 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - November 15, 2017 Category: Surgery Authors: Lundström KJ, Holmberg H, Montgomery A, Nordin P Tags: Br J Surg Source Type: research

Population-based incidence rate of inpatient and outpatient surgical procedures in a high-income country.
This report describes these data for Sweden, a high-income country. METHODS: In an 8-year population-based observational cohort study, all inpatient and outpatient care in the public and private sectors was detected in the Swedish National Patient Register and screened for the occurrence of surgery. The entire Swedish population was eligible for inclusion. All patients attending healthcare for any disease were included. Incidence rates of surgery and likelihood of surgery were calculated, with trends over time, and correlation with sex, age and disease category. RESULTS: Almost one in three hospitalizations invol...
Source: The British Journal of Surgery - November 13, 2017 Category: Surgery Authors: Omling E, Jarnheimer A, Rose J, Björk J, Meara JG, Hagander L Tags: Br J Surg Source Type: research

Risk score to predict biliary leakage after elective liver resection.
Group Abstract BACKGROUND: Biliary leakage remains a major cause of morbidity after liver resection. Previous prognostic studies of posthepatectomy biliary leakage (PHBL) lacked power, population homogeneity, and model validation. The present study aimed to develop a risk score for predicting severe PHBL. METHODS: In this multicentre observational study, patients who underwent liver resection without hepaticojejunostomy in one of nine tertiary centres between 2012 and 2015 were randomly assigned to a development or validation cohort in a 2 : 1 ratio. A model predicting severe PHBL (International...
Source: The British Journal of Surgery - November 13, 2017 Category: Surgery Authors: Mohkam K, Farges O, Vibert E, Soubrane O, Adam R, Pruvot FR, Regimbeau JM, Adham M, Boleslawski E, Mabrut JY, of the Association de Chirurgie Hépato-Biliaire et de Transplantation (ACHBT) French Hepatectomy Study Group Tags: Br J Surg Source Type: research

Savings from reducing low-value general surgical interventions.
CONCLUSION: Low-value services place a burden on health budgets. Stopping only five high-volume, high-cost general surgical procedures could save the National Health Service €153 million per annum. PMID: 29114846 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - November 8, 2017 Category: Surgery Authors: Malik HT, Marti J, Darzi A, Mossialos E Tags: Br J Surg Source Type: research

MiR-128 regulation of glucose metabolism and cell proliferation in triple-negative breast cancer.
Abstract BACKGROUND: Triple-negative breast cancer (TNBC) is prone to metastasis and has a poor prognosis, with lower survival rates than other breast cancer subtypes. MicroRNAs have recently emerged as powerful regulators of cancer processes and become a promising target in cancer therapy. METHODS: Expression of miR-128 was examined in invasive ductal breast cancer, and its relationship with clinicopathological features analysed. A series of in vitro and in vivo experiments were performed to investigate the function and mechanism of miR-128 in the development of invasive ductal breast cancer. RESULTS: A...
Source: The British Journal of Surgery - November 8, 2017 Category: Surgery Authors: Xiao M, Lou C, Xiao H, Yang Y, Cai X, Li C, Jia S, Huang Y Tags: Br J Surg Source Type: research

Cardiovascular and all-cause mortality in patients with intermittent claudication and critical limb ischaemia.
Abstract BACKGROUND: The aim of this study was to evaluate absolute mortality risks and to determine whether changes in mortality risk occurred in patients with intermittent claudication (IC) or critical limb ischaemia (CLI) in the Netherlands between 1998 and 2010. METHODS: Data for patients treated between 1998 and 2010 were obtained from Dutch nationwide registers: the Hospital Discharge Register, Population Register and Cause of Death Register. The registers were used to obtain information regarding IC and CLI hospitalizations, co-morbidities, demographic factors, and date and cause of death. The cohort w...
Source: The British Journal of Surgery - November 8, 2017 Category: Surgery Authors: van Haelst STW, Koopman C, den Ruijter HM, Moll FL, Visseren FL, Vaartjes I, de Borst GJ Tags: Br J Surg Source Type: research

All-cause and cardiovascular mortality risk after surgery versus radioiodine treatment for hyperthyroidism.
CONCLUSION: Compared with treatment with radioiodine, surgery for hyperthyroidism is associated with a lower risk of all-cause and cardiovascular mortality in the long term. This finding was more evident among men. PMID: 29116656 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - November 8, 2017 Category: Surgery Authors: Giesecke P, Frykman V, Wallin G, Lönn S, Discacciati A, Törring O, Rosenqvist M Tags: Br J Surg Source Type: research

International validation of the European Organisation for Research and Treatment of Cancer QLQ-BRECON23 quality-of-life questionnaire for women undergoing breast reconstruction.
nt of Cancer Quality of Life Group Abstract BACKGROUND: The aim was to carry out phase 4 international field-testing of the European Organisation for Research and Treatment of Cancer (EORTC) breast reconstruction (BRECON) module. The primary objective was finalization of its scale structure. Secondary objectives were evaluation of its reliability, validity, responsiveness, acceptability and interpretability in patients with breast cancer undergoing mastectomy and reconstruction. METHODS: The EORTC module development guidelines were followed. Patients were recruited from 28 centres in seven countries. A prospe...
Source: The British Journal of Surgery - November 8, 2017 Category: Surgery Authors: Winters ZE, Afzal M, Rutherford C, Holzner B, Rumpold G, da Costa Vieira RA, Hartup S, Flitcroft K, Bjelic-Radisic V, Oberguggenburger A, Panouilleres M, Mani M, Catanuto G, Douek M, Kokan J, Sinai P, King MT, European Organisation for Research and Treatm Tags: Br J Surg Source Type: research

Optimal extent of completion lymphadenectomy for patients with melanoma and a positive sentinel node in the groin.
CONCLUSION: There was no significant difference in recurrence pattern and survival rates between patients undergoing inguinal or ilioinguinal dissection after a positive SNB, even after stratification for a positive CLND result. An inguinal dissection is a safe first approach as CLND in patients with a positive SNB. PMID: 29095479 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - November 2, 2017 Category: Surgery Authors: Verver D, Madu MF, Oude Ophuis CMC, Faut M, de Wilt JHW, Bonenkamp JJ, Grünhagen DJ, van Akkooi ACJ, Verhoef C, van Leeuwen BL Tags: Br J Surg Source Type: research

Meta-analysis of microsatellite instability in relation to clinicopathological characteristics and overall survival in gastric cancer.
Abstract BACKGROUND: Several associations between microsatellite instability (MSI) and other clinicopathological factors have been reported in gastric cancer, but the results have been ambiguous. This systematic review and meta-analysis investigated the relationship between MSI and overall survival and clinicopathological characteristics of patients with gastric cancer. METHODS: A systematic literature search of the PubMed, Cochrane and Ovid databases until 31 January 2016 was performed in accordance with the PRISMA statement. The articles were screened independently according to PICO (population, interventio...
Source: The British Journal of Surgery - November 1, 2017 Category: Surgery Authors: Polom K, Marano L, Marrelli D, De Luca R, Roviello G, Savelli V, Tan P, Roviello F Tags: Br J Surg Source Type: research

Randomized clinical trial of hepatic resection versus radiofrequency ablation for early-stage hepatocellular carcinoma.
CONCLUSION: RFA for early-stage HCC is not superior to hepatic resection, in terms of tumour recurrence, overall survival and disease-free survival. Registration number: HKUCTR-10 (http://www.hkuctr.com). PMID: 29091283 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - November 1, 2017 Category: Surgery Authors: Ng KKC, Chok KSH, Chan ACY, Cheung TT, Wong TCL, Fung JYY, Yuen J, Poon RTP, Fan ST, Lo CM Tags: Br J Surg Source Type: research

Meta-analysis of the impact of surgical approach on the grade of mesorectal excision in rectal cancer.
CONCLUSION: Small differences in mesorectal quality were evident between open and laparoscopic rectal resections. This may be attributable to use of laparoscopic instruments; however, to date minor defects have not affected oncological outcomes. PMID: 29044484 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - October 19, 2017 Category: Surgery Authors: Creavin B, Kelly ME, Ryan E, Winter DC Tags: Br J Surg Source Type: research

Spanish translation section.
Authors: PMID: 29044486 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - October 19, 2017 Category: Surgery Tags: Br J Surg Source Type: research

The challenges of surgical research in children.
PMID: 29044487 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - October 19, 2017 Category: Surgery Authors: Losty PD Tags: Br J Surg Source Type: research

Randomized feasibility trial of replacing or discarding the nail plate after nail-bed repair in children.
CONCLUSION: Recruitment was rapid and nail-bed repair appeared to have low complication and infection rates in this pilot trial. The findings have led to revision of the definitive trial protocol, including the mode and timing of follow-up, and modification of the Zook classification. PMID: 29044488 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - October 19, 2017 Category: Surgery Authors: Greig A, Gardiner MD, Sierakowski A, Zweifel CJ, Pinder RM, Furniss D, Cook JA, Beard D, Farrar N, Cooper CD, Jain A, NINJA Pilot Collaborative Tags: Br J Surg Source Type: research

Morbidity of cholecystectomy and gastric bypass in a national database.
m G Abstract BACKGROUND: There is a strong association between obesity and gallstones. However, there is no clear evidence regarding the optimal order of Roux-en-Y gastric bypass (RYGB) and cholecystectomy when both procedures are clinically indicated. METHODS: Based on cross-matched data from the Swedish Register for Cholecystectomy and Endoscopic Retrograde Cholangiopancreatography (GallRiks; 79 386 patients) and the Scandinavian Obesity Surgery Registry (SOReg; 36 098 patients) from 2007 to 2013, complication rates, reoperation rates and operation times related to the timing of RYGB and cholecystectomy wer...
Source: The British Journal of Surgery - October 18, 2017 Category: Surgery Authors: Wanjura V, Szabo E, Österberg J, Ottosson J, Enochsson L, Sandblom G Tags: Br J Surg Source Type: research

Prognostic value of the cancer oncogene Kelch-like 6 in gastric cancer.
CONCLUSION: Abnormal expression of the KLHL6 oncogene promoted GC progression in vitro and in vivo, and its expression level in tumour tissue was found to be of prognostic value. PMID: 29044464 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - October 17, 2017 Category: Surgery Authors: Deng J, Guo J, Ma G, Zhang H, Sun D, Hou Y, Xie X, Guo X, Nie Y, Liang H Tags: Br J Surg Source Type: research

Meta-analysis of the association between peripheral artery disease and growth of abdominal aortic aneurysms.
CONCLUSION: This systematic review suggests that currently reported studies demonstrate no robust and consistent association between PAD and reduced AAA growth. PMID: 29044481 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - October 17, 2017 Category: Surgery Authors: Matthews EO, Rowbotham SE, Moxon JV, Jones RE, Vega de Ceniga M, Golledge J Tags: Br J Surg Source Type: research

Population-based study of factors predicting treatment intention in patients with locally recurrent rectal cancer.
CONCLUSION: Non-central location of the LRRC, presence of symptoms and age at least 80 years at diagnosis of the LRRC were associated with treatment with palliative intent. PMID: 29023631 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - October 12, 2017 Category: Surgery Authors: Westberg K, Palmer G, Hjern F, Nordenvall C, Johansson H, Holm T, Martling A Tags: Br J Surg Source Type: research

Revised Functional Capacity Index as a predictor of outcome following injury.
This study aimed to assess the 12-month functional outcome predictions of pFCI08 in a major trauma population, and to test the assumptions made by its developers to ensure population homogeneity. METHODS: Patients with major trauma from Victoria, Australia, were followed up using routine telephone interviews. Assessment of survivors 12 months after injury included the Glasgow Outcome Scale - Extended (GOS-E). κ scores were used to measure agreement between pFCI08 and assessed GOS-E scores. RESULTS: Of 20 098 patients with severe injury, 12 417 had both pFCI08 and GOS-E scoring available at 12 ...
Source: The British Journal of Surgery - October 12, 2017 Category: Surgery Authors: Palmer CS, Gabbe BJ, Cameron PA Tags: Br J Surg Source Type: research

Randomized feasibility trial of high-intensity interval training before elective abdominal aortic aneurysm repair.
CONCLUSION: Despite the intensity of exercise being generally lower than intended, the findings support the feasibility and acceptability of both preoperative HIT and the trial procedures. A definitive trial is warranted. Registration number: ISRCTN09433624 ( https://www.isrctn.com/). PMID: 28990651 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - October 9, 2017 Category: Surgery Authors: Tew GA, Batterham AM, Colling K, Gray J, Kerr K, Kothmann E, Nawaz S, Weston M, Yates D, Danjoux G Tags: Br J Surg Source Type: research

Axillary tumour burden in women with a fine-needle aspiration/core biopsy-proven positive node on ultrasonography compared to women with a positive sentinel node.
Abstract BACKGROUND: The sensitivity of axillary ultrasonography (AUS) has increased in recent years, enabling detection of even low-volume axillary nodal metastases. The aim here was to evaluate the axillary tumour burden in women with a fine-needle aspiration/core biopsy-proven positive node on AUS and in those with a positive sentinel node biopsy (SNB). METHODS: This retrospective cohort study included all patients with early breast cancer who had AUS and axillary lymph node dissection (ALND) between 2011 and 2014. RESULTS: A total of 332 patients who had ALND were eligible for the study, 191 (57&midd...
Source: The British Journal of Surgery - October 9, 2017 Category: Surgery Authors: Lloyd P, Theophilidou E, Newcombe RG, Pugh L, Goyal A Tags: Br J Surg Source Type: research

Randomized clinical trial of immersive virtual reality tour of the operating theatre in children before anaesthesia.
This study was designed to determine whether a preoperative VR tour could reduce preoperative anxiety in children. METHODS: Children scheduled for elective surgery under general anaesthesia were randomized into a control or VR group. The control group received conventional information regarding anaesthesia and surgery. The VR group watched a 4-min video showing Pororo, the famous little penguin, visiting the operating theatre and explaining what is in it. The main outcome was preoperative anxiety, assessed using the modified Yale Preoperative Anxiety Scale (m-YPAS) before entering the operating theatre. Secondary outc...
Source: The British Journal of Surgery - October 4, 2017 Category: Surgery Authors: Ryu JH, Park SJ, Park JW, Kim JW, Yoo HJ, Kim TW, Hong JS, Han SH Tags: Br J Surg Source Type: research

Non-inferiority and equivalence trials.
PMID: 28895139 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - September 14, 2017 Category: Surgery Authors: Ranstam J, Cook JA Tags: Br J Surg Source Type: research

Improving outcomes in patients with resectable pancreatic cancer.
PMID: 28895140 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - September 14, 2017 Category: Surgery Authors: Roberts KJ Tags: Br J Surg Source Type: research

Scientific surgery.
Authors: PMID: 28895141 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - September 14, 2017 Category: Surgery Tags: Br J Surg Source Type: research

Randomized clinical trial of laparoscopic versus open pancreatoduodenectomy for periampullary tumours.
Abstract BACKGROUND: Laparoscopic resection as an alternative to open pancreatoduodenectomy may yield short-term benefits, but has not been investigated in a randomized trial. The aim of this study was to compare laparoscopic and open pancreatoduodenectomy for short-term outcomes in a randomized trial. METHODS: Patients with periampullary cancers were randomized to either laparoscopic or open pancreatoduodenectomy. The outcomes evaluated were hospital stay (primary outcome), and blood loss, radicality of surgery, duration of operation and complication rate (secondary outcomes). RESULTS: Of 268 patients, ...
Source: The British Journal of Surgery - September 14, 2017 Category: Surgery Authors: Palanivelu C, Senthilnathan P, Sabnis SC, Babu NS, Srivatsan Gurumurthy S, Anand Vijai N, Nalankilli VP, Praveen Raj P, Parthasarathy R, Rajapandian S Tags: Br J Surg Source Type: research

Randomized clinical trial of laparoscopic ultrasonography before laparoscopic colorectal cancer resection.
CONCLUSION: Routine LUS during resection of colorectal cancer is not recommended. Registration number: NCT02079389 (http://www.clinicaltrials.gov). PMID: 28895143 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - September 14, 2017 Category: Surgery Authors: Ellebaek SB, Fristrup CW, Hovendal C, Qvist N, Bundgaard L, Salomon S, Støvring J, Mortensen MB Tags: Br J Surg Source Type: research

Spanish translation section.
Authors: PMID: 28895144 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - September 14, 2017 Category: Surgery Tags: Br J Surg Source Type: research

Use of endoscopy to determine the resection margin during laparoscopic gastrectomy for cancer.
CONCLUSION: Preoperative placement of marking clips and intraoperative endoscopy is helpful in the determination of a safe surgical margin in patients with gastric cancer who undergo laparoscopic gastrectomy. PMID: 28892131 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - September 11, 2017 Category: Surgery Authors: Kawakatsu S, Ohashi M, Hiki N, Nunobe S, Nagino M, Sano T Tags: Br J Surg Source Type: research

Meta-analysis of the association between alcohol consumption and abdominal aortic aneurysm.
CONCLUSION: Although the linear dose-response analysis revealed little evidence of an association between alcohol consumption and AAA risk, a tick-shaped trend in the association was observed. This non-linear dose-response analysis revealed reduced risks for alcohol consumption below 2 units/day, masking increased risks for 2 or more units/day. PMID: 28880391 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - September 7, 2017 Category: Surgery Authors: Spencer SM, Trower AJ, Jia X, Scott DJA, Greenwood DC Tags: Br J Surg Source Type: research

#colorectalsurgery.
CONCLUSION: Online global communities formed via healthcare-related hashtags, such as #colorectalsurgery, unify social media posts, scientists, surgeons and authors who have an interest in coloproctology. Furthermore, they facilitate greater connectivity among geographically separate users. PMID: 28881004 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - September 7, 2017 Category: Surgery Authors: Brady RRW, Chapman SJ, Atallah S, Chand M, Mayol J, Lacy AM, Wexner SD Tags: Br J Surg Source Type: research

Superparamagnetic iron oxide nanoparticles as the sole method for sentinel node biopsy detection in patients with breast cancer.
rnberg F Abstract BACKGROUND: Sentinel node biopsy (SNB) using superparamagnetic iron oxide (SPIO) nanoparticles is a novel method in breast cancer. Several studies have verified the non-inferiority of SPIO compared with the standard use of radioisotope (99m) Tc with or without blue dye. The aim of the MONOS study presented here was to evaluate the use of SPIO as a sole tracer and the efficacy of tracer injection in the preoperative setting. METHODS: This prospective cohort study was carried out in two hospitals, one using (99m) Tc and the other SPIO. (99m) Tc was injected in the morning of the day of surgery...
Source: The British Journal of Surgery - September 6, 2017 Category: Surgery Authors: Karakatsanis A, Daskalakis K, Stålberg P, Olofsson H, Andersson Y, Eriksson S, Bergkvist L, Wärnberg F Tags: Br J Surg Source Type: research