Effect of preoperative biliary drainage on cholestasis-associated inflammatory and fibrotic gene signatures in perihilar cholangiocarcinoma.
Abstract Preoperative biliary drainage (PBD) is used routinely in the evaluation of patients with potentially resectable perihilar cholangiocarcinoma to relieve cholestasis and improve the liver's resilience to surgery. Little preclinical or translatational data are, however, currently available to guide the use of PBD in this patient group. The effect of PBD on hepatic gene expression profiles was therefore studied by microarray analysis. Drainage affects inflammatory and fibrotic gene signatures. PMID: 30395349 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - November 5, 2018 Category: Surgery Authors: Reiniers MJ, de Haan L, Weijer R, Wiggers JK, Jongejan A, Moerland PD, Alles LK, van Kampen AHC, van Gulik TM, Heger M, van Golen RF Tags: Br J Surg Source Type: research

Sex differences in national rates of repair of emergency abdominal aortic aneurysm.
CONCLUSION: Women who present as an emergency with an AAA are less likely to undergo repair than men. Although some of this can be explained by differences in age and co-morbidities, the differences persist after case-mix adjustment. PMID: 30395361 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - November 5, 2018 Category: Surgery Authors: Aber A, Tong TS, Chilcott J, Thokala P, Maheswaran R, Thomas SM, Nawaz S, Walters S, Michaels J Tags: Br J Surg Source Type: research

Survival after neoadjuvant chemoradiotherapy and oesophagectomy versus definitive chemoradiotherapy for patients with oesophageal squamous cell carcinoma.
Abstract BACKGROUND: Whether there is a difference in survival after neoadjuvant chemoradiotherapy plus surgery (CRT-S) compared with definitive chemoradiotherapy (dCRT) in patients with locally advanced oesophageal squamous cell carcinoma (SCC) remains controversial. METHODS: Patients with SCC who underwent curative treatment from 2008 to 2014 were identified from the Taiwan Cancer Registry. Propensity score matching was undertaken to balance pretreatment clinical variables. Overall survival was compared between patients undergoing CRT-S or dCRT. Univariable and multivariable analyses were performed to ident...
Source: The British Journal of Surgery - November 5, 2018 Category: Surgery Authors: Wang BY, Wu SC, Chen HC, Hung WH, Lin CH, Huang CL, Chen HS Tags: Br J Surg Source Type: research

Systematic review of treatment intensification using novel agents for chemoradiotherapy in rectal cancer.
CONCLUSION: Despite extensive research and promising preclinical studies, a definite further agent in addition to fluoropyrimidines that consistently improves response rate has yet to be found. PMID: 30311641 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - October 14, 2018 Category: Surgery Authors: Clifford R, Govindarajah N, Parsons JL, Gollins S, West NP, Vimalachandran D Tags: Br J Surg Source Type: research

Meta-analysis of sentinel lymph node biopsy after neoadjuvant chemotherapy in patients with initial biopsy-proven node-positive breast cancer.
CONCLUSION: Sentinel lymph node biopsy after neoadjuvant chemotherapy in patients with biopsy-proven node-positive breast cancer is accurate and reliable, but requires careful patient selection and optimal surgical techniques. PMID: 30311642 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - October 14, 2018 Category: Surgery Authors: Tee SR, Devane LA, Evoy D, Rothwell J, Geraghty J, Prichard RS, McDermott EW Tags: Br J Surg Source Type: research

From retribution to reconciliation after critical events in surgery.
PMID: 30311643 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - October 14, 2018 Category: Surgery Authors: de Vos MS, Hamming JF Tags: Br J Surg Source Type: research

Snapshot quiz.
Authors: PMID: 30311646 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - October 14, 2018 Category: Surgery Tags: Br J Surg Source Type: research

Snapshot quiz.
Authors: PMID: 30311647 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - October 14, 2018 Category: Surgery Tags: Br J Surg Source Type: research

Systematic review of the safety and efficacy of osseointegration prosthesis after limb amputation.
CONCLUSION: Osseointegration after limb amputation improves prosthetic use, comfort when sitting, walking ability, mobility, gait and quality of life. However, it is associated with an increased risk of soft tissue infection. PMID: 30307036 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - October 11, 2018 Category: Surgery Authors: Kunutsor SK, Gillatt D, Blom AW Tags: Br J Surg Source Type: research

Development and validation of a nomogram to predict recurrence and melanoma-specific mortality in patients with negative sentinel lymph nodes.
CONCLUSION: A nomogram for predicting recurrence and MSM in patients with melanoma and negative SNs was constructed and validated. It could provide personalized estimates useful for tailoring surveillance strategies (reduce or increase intensity), and selection of patients for adjuvant therapy or clinical trials. PMID: 30307046 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - October 11, 2018 Category: Surgery Authors: Verver D, van Klaveren D, Franke V, van Akkooi ACJ, Rutkowski P, Keilholz U, Eggermont AMM, Nijsten T, Grünhagen DJ, Verhoef C Tags: Br J Surg Source Type: research

Feasibility study of combined dynamic imaging and lymphaticovenous anastomosis surgery for breast cancer-related lymphoedema.
CONCLUSION: LVA resulted in a sustained volume reduction in selected patients and may offset the burden of CGT. Further work is required to identify biomarkers that predict a favourable response to LVA surgery. PMID: 30295931 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - October 8, 2018 Category: Surgery Authors: Khan AA, Hernan I, Adamthwaite JA, Ramsey KWD Tags: Br J Surg Source Type: research

Disparities in the management of paediatric splenic injury.
Abstract BACKGROUND: The non-operative management of splenic injury in children is recommended widely, and is possible in over 95 per cent of episodes. Practice appears to vary between centres. METHODS: The Trauma Audit and Research Network (TARN) database was interrogated to determine the management of isolated paediatric splenic injuries in hospitals in England and Wales. Rates of non-operative management, duration of hospital stay, readmission and mortality were recorded. Management in paediatric surgical hospitals was compared with that in adult hospitals. RESULTS: Between January 2000 and December 2...
Source: The British Journal of Surgery - October 2, 2018 Category: Surgery Authors: Warwick AM, Jenks T, Fisher R, Garrett-Cox R, Lecky F, Yates D Tags: Br J Surg Source Type: research

Experimental study of needle recording electrodes placed on the thyroid cartilage for neuromonitoring during thyroid surgery.
CONCLUSION: EMG amplitudes obtained using TC electrodes were higher, and identified RLN injury earlier than ET electrodes. Surgical relevance Needle electrodes placed on the thyroid cartilage (TC) are an alternative to endotracheal tube (ET) electrodes for assessing the function of the recurrent laryngeal nerve (RLN) in thyroid surgery. This study used an experimental porcine model to evaluate the use of needle electrodes inserted in the TC, compared with ET electrodes, for producing an electromyographic (EMG) profile of the RLN. Nine areas of the TC, with various needle insertion depths and orientations, were compared. Pe...
Source: The British Journal of Surgery - October 1, 2018 Category: Surgery Authors: Zhao Y, Li C, Zhang D, Zhou L, Liu X, Li S, Wang T, Dionigi G, Sun H Tags: Br J Surg Source Type: research

Snapshot quiz.
Authors: PMID: 30221766 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - September 18, 2018 Category: Surgery Tags: Br J Surg Source Type: research

Trials and tribulations of neoadjuvant therapy in pancreatic cancer.
ide K PMID: 30221767 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - September 18, 2018 Category: Surgery Authors: Del Chiaro M, Søreide K Tags: Br J Surg Source Type: research

Snapshot quiz.
Authors: PMID: 30221769 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - September 18, 2018 Category: Surgery Tags: Br J Surg Source Type: research

Population-based analysis of the impact of trauma on longer-term functional outcomes.
CONCLUSION: Patients experiencing minor or major trauma received high levels of medical benefits; however, most recovered within the first year and resumed preinjury work activity. Patients with severe trauma were more likely to receive medical benefits and have a delayed return to work. Registration number: NCT02602405 (http://www.clinicaltrials.gov). PMID: 30221344 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - September 17, 2018 Category: Surgery Authors: Uleberg O, Pape K, Kristiansen T, Romundstad PR, Klepstad P Tags: Br J Surg Source Type: research

Bowel dysfunction after sigmoid resection for cancer and its impact on quality of life.
Abstract BACKGROUND: Several studies have explored functional outcomes after rectal cancer surgery, but bowel dysfunction after sigmoid resection for cancer has hardly been considered. The aim of this study was to identify the prevalence and pattern of bowel dysfunction after resection for sigmoid cancer, and the impact of bowel function on quality of life (QoL) by comparison with patients who had polypectomy for cancer. METHODS: This was a national cross-sectional study. Data were collected from the Danish Colorectal Cancer Group database, and a questionnaire regarding bowel function and European Organizatio...
Source: The British Journal of Surgery - September 13, 2018 Category: Surgery Authors: Elfeki H, Larsen HM, Emmertsen KJ, Christensen P, Youssef M, Khafagy W, Omar W, Laurberg S Tags: Br J Surg Source Type: research

Network meta-analysis of topical haemostatic agents in thyroid surgery.
CONCLUSION: The general use of local haemostatic agents has not been shown to reduce the rate of clinically relevant bleeding. PMID: 30199093 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - September 10, 2018 Category: Surgery Authors: Polychronidis G, Hüttner FJ, Contin P, Goossen K, Uhlmann L, Heidmann M, Knebel P, Diener MK, Büchler MW, Probst P Tags: Br J Surg Source Type: research

Multicentre study of the prognostic impact of preoperative bodyweight on long-term prognosis of hepatocellular carcinoma.
This study aimed to investigate the relationship of patient weight with long-term recurrence and overall survival (OS) after curative liver resection for HCC. METHODS: Data for patients with HCC who underwent curative liver resection between 2000 and 2015 in five centres in China were analysed retrospectively in three groups according to their preoperative BMI: underweight (BMI 18·4 kg/m2 or less), normal weight (BMI 18·5-24·9 kg/m2 ) and overweight (BMI 25·0 kg/m2 or above). Patients' baseline characteristics, operative variables and long-term survival outcomes were co...
Source: The British Journal of Surgery - September 10, 2018 Category: Surgery Authors: Yu JJ, Shen F, Chen TH, Liang L, Han J, Xing H, Zhou YH, Wang H, Gu WM, Lau WY, Yang T Tags: Br J Surg Source Type: research

Snapshot quiz.
Authors: PMID: 30133761 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - August 23, 2018 Category: Surgery Tags: Br J Surg Source Type: research

Timing of carotid intervention.
PMID: 30133763 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - August 23, 2018 Category: Surgery Authors: Meershoek AJA, de Borst GJ Tags: Br J Surg Source Type: research

Snapshot quiz.
Authors: PMID: 30133764 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - August 23, 2018 Category: Surgery Tags: Br J Surg Source Type: research

The Anatomy Lesson of Willem R öell, painted in 1728.
The Anatomy Lesson of Willem Röell, painted in 1728. Br J Surg. 2018 Sep;105(10):1273 Authors: IJpma FFA, van Gulik TM Abstract The Anatomy Lesson of Willem Röell, painted by Cornelis Troost in 1728, should be considered a group portrait of the Amsterdam Guild of Surgeons. Professor Röell, praelector anatomiae (lecturer in anatomy) of the Surgeons' Guild, was portrayed while performing an anatomical dissection of the knee joint in the corpse of an elderly man. The three surgeons in the painting, dressed in fashionable suits, held important positions as governors of the Guild. The Guild ...
Source: The British Journal of Surgery - August 23, 2018 Category: Surgery Authors: IJpma FFA, van Gulik TM Tags: Br J Surg Source Type: research

LASSO regression.
PMID: 30133766 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - August 23, 2018 Category: Surgery Authors: Ranstam J, Cook JA Tags: Br J Surg Source Type: research

Predicting risk of rupture and rupture-preventing reinterventions following endovascular abdominal aortic aneurysm repair.
CONCLUSION: Secondary sac growth is an important predictor of rupture or rupture-preventing reintervention to enable the development of personalized surveillance intervals. A dynamic prognostic model has the potential to tailor surveillance by identifying a large proportion of patients who may require less intensive follow-up. PMID: 30133767 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - August 23, 2018 Category: Surgery Authors: Grootes I, Barrett JK, Ulug P, Rohlffs F, Laukontaus SJ, Tulamo R, Venermo M, Greenhalgh RM, Sweeting MJ Tags: Br J Surg Source Type: research

Overall survival before and after centralization of gastric cancer surgery in the Netherlands.
CONCLUSION: Centralization of gastric cancer surgery was associated with reduced postoperative mortality and improved survival. PMID: 30132789 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - August 22, 2018 Category: Surgery Authors: van Putten M, Nelen SD, Lemmens VEPP, Stoot JHMB, Hartgrink HH, Gisbertz SS, Spillenaar Bilgen EJ, Heisterkamp J, Verhoeven RHA, Nieuwenhuijzen GAP Tags: Br J Surg Source Type: research

Long-term outcomes of endovenous laser ablation and conventional surgery for great saphenous varicose veins.
Abstract BACKGROUND: Clinical guidelines recommend endovenous laser ablation (EVLA) over surgery based on short-term evidence, yet there are few studies reporting mid- to long-term outcomes. The aim of this study was to report the 5-year outcomes from an RCT of surgery versus EVLA for treatment of symptomatic great saphenous varicose veins. METHODS: Patients with symptomatic varicose veins due to great saphenous vein (GSV) incompetence were followed up 5 years after enrolment in a randomized trial of either surgery (saphenofemoral junction ligation, GSV strip to the knee and multiple avulsions of varic...
Source: The British Journal of Surgery - August 22, 2018 Category: Surgery Authors: Wallace T, El-Sheikha J, Nandhra S, Leung C, Mohamed A, Harwood A, Smith G, Carradice D, Chetter I Tags: Br J Surg Source Type: research

Current practice and short-term outcomes of therapeutic mammaplasty in the international TeaM multicentre prospective cohort study.
CONCLUSION: Therapeutic mammaplasty is a safe and effective alternative to mastectomy or standard breast-conserving surgery. Further work is required to explore the impact of the technique on quality of life, and to establish cost-effectiveness. PMID: 30132807 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - August 22, 2018 Category: Surgery Authors: O'Connell RL, Baker E, Trickey A, Rattay T, Whisker L, Macmillan RD, Potter S, TeaM Steering Group and the Mammary Fold Academic and Research Collaborative Tags: Br J Surg Source Type: research

Oesophagectomy with or without supraclavicular lymphadenectomy after neoadjuvant treatment for squamous cell carcinoma of the oesophagus.
CONCLUSION: For patients with clinically negative supraclavicular lymph nodes, prophylactic supraclavicular lymphadenectomy may be omitted when neoadjuvant treatment is administered. PMID: 30106170 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - August 14, 2018 Category: Surgery Authors: Mine S, Watanabe M, Kumagai K, Okamura A, Yamashita K, Hayami M, Yuda M, Imamura Y, Ishizuka N Tags: Br J Surg Source Type: research

Importance of main pancreatic duct dilatation in IPMN undergoing surveillance.
Abstract BACKGROUND: The association between risk of pancreatic cancer and a dilated main pancreatic duct (MPD) in intraductal papillary mucinous neoplasm (IPMN) is debated. The aim of this study was to assess the role of MPD size in predicting pancreatic cancer in resected IPMNs and those kept under surveillance. METHODS: All patients with IPMN referred to the Pancreas Institute, University of Verona Hospital Trust, from 2006 to 2016 were included. The primary endpoint was the occurrence of malignancy detected at surgery or during follow-up. RESULTS: The final cohort consisted of 1688 patients with a me...
Source: The British Journal of Surgery - August 14, 2018 Category: Surgery Authors: Marchegiani G, Andrianello S, Morbin G, Secchettin E, D'Onofrio M, De Robertis R, Malleo G, Bassi C, Salvia R Tags: Br J Surg Source Type: research

CCR-CARESS score for predicting operative mortality in patients with colorectal cancer.
CONCLUSION: Elderly patients with co-morbidity and palliative intention of surgery have an unacceptably high risk of death. PMID: 30102425 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - August 13, 2018 Category: Surgery Authors: Baré M, Mora L, Torà N, Gil MJ, Barrio I, Collera P, Suárez D, Redondo M, Escobar A, Fernández de Larrea N, Quintana JM, CCR-CARESS Study Group Tags: Br J Surg Source Type: research

Nationwide population-based study of trends and regional variation in breast-conserving treatment for breast cancer.
CONCLUSION: This large nationwide study showed that the use of BCS increased from 1989 to 2015 in the Netherlands. After adjustment for explanatory variables, a large variation still existed between the nine regions. This regional variation underlines the need for implementation of a uniform treatment and decision-making strategy. PMID: 30091459 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - August 9, 2018 Category: Surgery Authors: van Maaren MC, Strobbe LJA, Koppert LB, Poortmans PMP, Siesling S Tags: Br J Surg Source Type: research

Preoperative oral care and effect on postoperative complications after major cancer surgery.
CONCLUSION: Preoperative oral care by a dentist significantly reduced postoperative complications in patients who underwent cancer surgery. PMID: 30088267 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - August 8, 2018 Category: Surgery Authors: Ishimaru M, Matsui H, Ono S, Hagiwara Y, Morita K, Yasunaga H Tags: Br J Surg Source Type: research

Prognostic implications of MRI-detected lateral nodal disease and extramural vascular invasion in rectal cancer.
CONCLUSION: Although lateral nodal disease is more a local problem, mrEMVI mainly predicts distant recurrence. The results of this study showed an unacceptably high local recurrence rate in patients with a short axis of 10 mm or more, despite neoadjuvant (chemo)radiotherapy. PMID: 30079958 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - August 6, 2018 Category: Surgery Authors: Schaap DP, Ogura A, Nederend J, Maas M, Cnossen JS, Creemers GJ, van Lijnschoten I, Nieuwenhuijzen GAP, Rutten HJT, Kusters M Tags: Br J Surg Source Type: research

Randomized clinical trial of stapler hepatectomy versus LigaSure ™ transection in elective hepatic resection.
CONCLUSION: Stapler hepatectomy was associated with reduced blood loss and a shorter duration of operation than the LigaSure™ device for parenchymal transection in elective partial hepatectomy. Registration number: NCT01858987 (http://www.clinicaltrials.gov). PMID: 30069876 [PubMed - in process] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - August 1, 2018 Category: Surgery Authors: Fritzmann J, Kirchberg J, Sturm D, Ulrich AB, Knebel P, Mehrabi A, Büchler MW, Weitz J, Reissfelder C, Rahbari NN Tags: Br J Surg Source Type: research

Population-based cohort study of diabetes mellitus and mortality in gastric adenocarcinoma.
CONCLUSION: These findings indicate a worse prognosis in patients with gastric adenocarcinoma and coexisting diabetes compared with those without diabetes. PMID: 30051463 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - July 27, 2018 Category: Surgery Authors: Zheng J, Xie SH, Santoni G, Lagergren J Tags: Br J Surg Source Type: research

Lymph node regression and survival following neoadjuvant chemotherapy in oesophageal adenocarcinoma.
Abstract BACKGROUND: The aim was to define the pathological response in lymph nodes following neoadjuvant chemotherapy for oesophageal adenocarcinoma and to quantify any associated survival benefit. METHODS: Lymph nodes retrieved at oesophagectomy were examined retrospectively by two pathologists for evidence of a response to chemotherapy. Patients were classified as lymph node-negative (either negative nodes with no evidence of previous tumour involvement or negative with evidence of complete regression) or positive (allocated a lymph node regression score based on the proportion of fibrosis to residual tumo...
Source: The British Journal of Surgery - July 26, 2018 Category: Surgery Authors: Davies AR, Myoteri D, Zylstra J, Baker CR, Wulaningsih W, Van Hemelrijck M, Maisey N, Allum WH, Smyth E, Gossage JA, Lagergren J, Cunningham D, Green M, Guy's and St Thomas' Oesophago-Gastric Research Group and PROGRESS Study Group Tags: Br J Surg Source Type: research

Open or endovascular revascularization in the treatment of acute lower limb ischaemia.
l;rck M Abstract BACKGROUND: Consensus is lacking regarding intervention for patients with acute lower limb ischaemia (ALI). The aim was to study amputation-free survival in patients treated for ALI by either primary open or endovascular revascularization. METHODS: The Swedish Vascular Registry (Swedvasc) was combined with the Population Registry and National Patient Registry to determine follow-up on mortality and amputation rates. Revascularization techniques were compared by propensity score matching 1 : 1. RESULTS: Of 9736 patients who underwent open surgery and 6493 who had endovascula...
Source: The British Journal of Surgery - July 25, 2018 Category: Surgery Authors: Grip O, Wanhainen A, Michaëlsson K, Lindhagen L, Björck M Tags: Br J Surg Source Type: research

Ruptured popliteal artery aneurysm.
k M Abstract BACKGROUND: Popliteal artery aneurysms (PAAs) are generally complicated by thrombosis and distal embolization, whereas rupture is rare. The aim of this study was to describe the clinical characteristics and outcome in a cohort of patients who had surgery for ruptured PAA (rPAA). METHODS: Operations for rPAA were identified from the Swedish Vascular Registry, Swedvasc, 1987-2012. Medical records and imaging were reviewed. Comparison was made with patients treated for PAA without rupture. RESULTS: Forty-five patients with rPAA were identified. The proportion with rupture among those operated o...
Source: The British Journal of Surgery - July 24, 2018 Category: Surgery Authors: Cervin A, Ravn H, Björck M Tags: Br J Surg Source Type: research

Pancreas-sparing, ampulla-preserving duodenectomy for major duodenal (D1-D2) perforations.
CONCLUSION: Pancreas-sparing, ampulla-preserving D1-D2 duodenectomy for emergency treatment of major duodenal perforations is feasible and associated with satisfactory outcomes. PMID: 30024637 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - July 19, 2018 Category: Surgery Authors: Di Saverio S, Segalini E, Birindelli A, Todero S, Podda M, Rizzuto A, Tugnoli G, Biondi A Tags: Br J Surg Source Type: research

Profile of exhaled-breath volatile organic compounds to diagnose pancreatic cancer.
CONCLUSION: Breath VOCs may distinguish patients with pancreatic cancer from those without cancer. PMID: 30019405 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - July 18, 2018 Category: Surgery Authors: Markar SR, Brodie B, Chin ST, Romano A, Spalding D, Hanna GB Tags: Br J Surg Source Type: research

Effect of aspirin in vascular surgery in patients from a randomized clinical trial (POISE-2).
CONCLUSION: This study suggests that the overall POISE-2 results apply to vascular surgery. Perioperative withdrawal of chronic aspirin therapy did not increase cardiovascular or vascular occlusive complications. Registration number: NCT01082874 ( http://www.clinicaltrials.gov). PMID: 30019751 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - July 18, 2018 Category: Surgery Authors: Biccard BM, Sigamani A, Chan MTV, Sessler DI, Kurz A, Tittley JG, Rapanos T, Harlock J, Szalay D, Tiboni ME, Popova E, Vásquez SM, Kabon B, Amir M, Mrkobrada M, Mehra BR, El Beheiry H, Mata E, Tena B, Sabaté S, Zainal Abidin MK, Shah VR, Balasubramanian Tags: Br J Surg Source Type: research

Multicentre international trial of laparoscopic lavage for Hinchey III acute diverticulitis (LLO Study).
CONCLUSION: Laparoscopic lavage showed a high rate of successful sepsis control in selected patients with perforated Hinchey III acute diverticulitis affected by peritonitis, with low rates of operative mortality, reoperation and stoma formation. PMID: 30006923 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - July 14, 2018 Category: Surgery Authors: Binda GA, Bonino MA, Siri G, Di Saverio S, Rossi G, Nascimbeni R, Sorrentino M, Arezzo A, Vettoretto N, Cirocchi R, LLO Study Group Tags: Br J Surg Source Type: research

Systematic review of the prevalence, impact and mitigating strategies for bullying, undermining behaviour and harassment in the surgical workplace.
CONCLUSION: Bullying, undermining behaviour and harassment are highly prevalent within surgery, and extremely damaging to victims. There is little high-quality research into counterstrategies, although professionalism training using simulated scenarios may be useful. PMID: 30007001 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - July 14, 2018 Category: Surgery Authors: Halim UA, Riding DM Tags: Br J Surg Source Type: research

Outcomes of pancreas retransplantation in patients with pancreas graft failure.
CONCLUSION: Pancreas retransplantation may be considered for patients whose previous graft has failed. PMID: 30007018 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - July 14, 2018 Category: Surgery Authors: Gasteiger S, Cardini B, Göbel G, Oberhuber R, Messner F, Resch T, Bösmüller C, Margreiter C, Schneeberger S, Maglione M Tags: Br J Surg Source Type: research

Obesity surgery and risk of cancer.
CONCLUSION: Bariatric surgery is associated with decreased risk of hormone-related cancers, whereas gastric bypass might increase the risk of colorectal cancer. PMID: 30003539 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - July 13, 2018 Category: Surgery Authors: Mackenzie H, Markar SR, Askari A, Faiz O, Hull M, Purkayastha S, Møller H, Lagergren J Tags: Br J Surg Source Type: research

Network meta-analysis of surgical management of gastro-oesophageal reflux disease in adults.
CONCLUSION: Posterior partial fundoplication provides the best balance of long-term, durable reflux control with less dysphagia, compared with other treatments. PMID: 30004114 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - July 13, 2018 Category: Surgery Authors: Amer MA, Smith MD, Khoo CH, Herbison GP, McCall JL Tags: Br J Surg Source Type: research

Meta-analysis of the prognostic role of perioperative platelet count in posthepatectomy liver failure and mortality.
CONCLUSION: A low perioperative PLT correlates with higher PHLF and mortality rates after hepatectomy. PMID: 29999190 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - July 12, 2018 Category: Surgery Authors: Mehrabi A, Golriz M, Khajeh E, Ghamarnejad O, Probst P, Fonouni H, Mohammadi S, Weiss KH, Büchler MW Tags: Br J Surg Source Type: research

Meta-analysis of prognostic factors for overall survival in patients with resected hilar cholangiocarcinoma.
CONCLUSION: Several tumour biological variables not included in the seventh edition of the AJCC classification affect overall survival. These require incorporation into prognostic models to ensure a personalized approach to prognostication and treatment. PMID: 29999515 [PubMed - as supplied by publisher] (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - July 12, 2018 Category: Surgery Authors: Bird NTE, McKenna A, Dodd J, Poston G, Jones R, Malik H Tags: Br J Surg Source Type: research