[Obesity hypoventilation syndrome and initial compliance with non-invasive ventilation].
CONCLUSION: Age greater than seventy-five years and being hospitalized for an acute exacerbation are predictors of better use of non-invasive ventilation in OHS. PMID: 33071059 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - October 21, 2020 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

Healthcare Shift Workers ’ Temporal Habits for Eating, Sleeping, and Light Exposure: A Multi-Instrument Pilot Study
Conclusion: This pilot study utilized primarily objective measurement to examine shift workers ’ habits outside the laboratory. Although no association between BMI and eating patterns/activity/sleep was observed across groups, a small, homogeneous sample may have influenced this. Overall, shift work was associated with 1) increased calorie intake and higher-fat and -carbohydrate diets and 2 ) sleep deprivation. A larger, more diverse sample can participate in future studies that objectively measure shift workers’ real-world habits. Published on 2020-10-21 10:20:23 (Source: Journal of Circadian Rhythms)
Source: Journal of Circadian Rhythms - October 21, 2020 Category: Biology Source Type: research

The prevalence, disease characteristics and treatment of chronic venous disease: an international web-based survey.
Conclusion: One in five adults had CVD, but most did not seek a physician's help. PMID: 33079592 [PubMed - as supplied by publisher] (Source: Journal of Comparative Effectiveness Research)
Source: Journal of Comparative Effectiveness Research - October 21, 2020 Category: General Medicine Tags: J Comp Eff Res Source Type: research

Obesity Drives Secondary Procedures to Achieve Access Maturation and Functionality in End-Stage Renal Disease
Establishment of long-term arteriovenous access is an important component in the long-term care of the patient with end-stage renal disease (ESRD). The increasing frequency of obesity is reported to have an impact on the access management of ESRD patients. The aim of this study was to evaluate the outcomes of arteriovenous fistula (AVF) in the obese and nonobese patients. (Source: Journal of Vascular Surgery)
Source: Journal of Vascular Surgery - October 21, 2020 Category: Surgery Authors: Qi Yan, Mark Davies Source Type: research

Amino Acid Sensing in Metabolic Homeostasis and Health.
Authors: Hu X, Guo F Abstract Sensing and responding to changes in nutrient levels, including those of glucose, lipids and amino acids, by the body is necessary for survival. Accordingly, perturbations in nutrient sensing are tightly linked with human pathologies, particularly metabolic diseases such as obesity, type 2 diabetes mellitus and other complications of metabolic syndromes. The conventional view is that amino acids are fundamental elements for protein and peptide synthesis, while recent studies have revealed that amino acids are also important bioactive molecules that play key roles in signaling pathway a...
Source: Endocrine Reviews - October 21, 2020 Category: Endocrinology Tags: Endocr Rev Source Type: research

Metabolic Changes Associated With the Use of Integrase Strand Transfer Inhibitors Among Virally Controlled Women
Conclusions: INSTI use was associated with unfavorable changes in HbA1c and systolic and diastolic BP during short-term follow-up. Further research is needed to understand long-term cardiometabolic effects of INSTI use. (Source: JAIDS Journal of Acquired Immune Deficiency Syndromes)
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - October 21, 2020 Category: Infectious Diseases Tags: Clinical Science Source Type: research

The Influence of Adherence to the Mediterranean Diet among Children and Their Parents in Relation to Childhood Overweight/Obesity: A Cross-Sectional Study in Greece.
Authors: Kosti RI, Kanellopoulou A, Fragkedaki E, Notara V, Giannakopoulou SP, Antonogeorgos G, Rojas-Gil AP, Kornilaki EN, Lagiou A, Panagiotakos DB Abstract Background: Childhood overweight/obesity constitutes a serious issue, as may cause several health problems. The main characteristics of the Mediterranean Diet have been acknowledged as the most appropriate shield mainly for obesity. Methods: The study was performed on 1728 primary students, during school years 2014-2016, in Greece. Children and their parents completed questionnaires which included dietary and lifestyle habits. The KIDMED score (range -4 to 12...
Source: Childhood Obesity - October 21, 2020 Category: Eating Disorders & Weight Management Tags: Child Obes Source Type: research

Fat Distribution among Children Born Extremely Low Birth Weight and Very Low Birth Weight: A Cohort Study.
Conclusion: Children born ELBW seem to have increased visceral fat thickness compared with children born VLBW. PMID: 33064560 [PubMed - as supplied by publisher] (Source: Childhood Obesity)
Source: Childhood Obesity - October 21, 2020 Category: Eating Disorders & Weight Management Tags: Child Obes Source Type: research

Confounding factors of transvaginal ultrasound accuracy in endometrial cancer.
Authors: Capozzi VA, Merisio C, Rolla M, Pugliese M, Morganelli G, Cianciolo A, Gambino G, Armano G, Sozzi G, Riccò M, Berretta R Abstract Endometrial cancer is the most frequently diagnosed gynecological tumour. Transvaginal ultrasound has a leading role in the preoperative evaluation of endometrial cancer patients. The study aimed to identify factors that can worsen the diagnostic accuracy of transvaginal ultrasound in endometrial cancer patients. We retrospectively analysed 290 patients with histological diagnosis of endometrial adenocarcinoma. Two-dimensional (2D) gray-scale ultrasound and power Doppler ...
Source: Journal of Obstetrics and Gynaecology - October 21, 2020 Category: OBGYN Tags: J Obstet Gynaecol Source Type: research

Caesarean delivery increases the risk of overweight or obesity in 2-year-old children.
In conclusion, significantly increased risk of overweight or obesity was found in 2-year-old children born via Caesarean delivery. Impact statement What is already known on this subject? Although there are studies on the relationship between childhood obesity and Caesarean Section delivery, results are inconsistent. What do the results of this study add? This is the first prospective cohort study showing the effect of Caesarean delivery on childhood obesity in Turkish children. What are the implications of these findings from clinical practice and/or further research? Future studies should further investigate the exact rea...
Source: Journal of Obstetrics and Gynaecology - October 21, 2020 Category: OBGYN Tags: J Obstet Gynaecol Source Type: research

Encouraging "Active Learning": Assessing Implementation of Head Start's Physical Activity Requirements Within the Teaching and Learning Environment.
CONCLUSION: Findings can help identify existing or potential strategies that could be adopted more widely or developed to assist Head Start programs incorporate PA into daily activities. PMID: 33065529 [PubMed - as supplied by publisher] (Source: Journal of Physical Activity and Health)
Source: Journal of Physical Activity and Health - October 21, 2020 Category: Sports Medicine Tags: J Phys Act Health Source Type: research

Association of Bioelectric Impedance Analysis Body Composition and disease severity in COVID-19 hospital ward and ICU patients: the BIAC-19 study
The current severe acute respiratory syndrome coronavirus 2 pandemic is unprecedented in its impact. It is essential to shed light on patient characteristics that predispose to a more severe disease course. Obesity, defined as a BMI>30kg/m2, is suggested to be one of these characteristics. However, BMI does not differentiate between fat mass and lean body mass, or the distribution of fat tissue. The aim of the present study was to assess the body composition of COVID-19 patients admitted to the ward or the ICU and identify any associations with severity of disease. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 21, 2020 Category: Nutrition Authors: Hanneke Pierre Franciscus Xaverius Moonen, Florianne Johanna Louise van Zanten, Luuk Driessen, Vivienne de Smet, Rianne Slingerland-Boot, Marco Mensink, Arthur Raymond Hubert van Zanten Tags: Original article Source Type: research

The Cross-Talk between Age, Hypertension and Inflammation in COVID-19 Patients: Therapeutic Targets
AbstractThis paper presents a brief overview of the complex interaction between age, hypertension, the renin –angiotensin–aldosterone system (RAAS), inflammation, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection. Coronavirus disease 2019 (COVID-19) is more frequent and more severe in comorbid elderly patients, especially those with hypertension, diabetes, obesity, or cardiovasc ular diseases. There are concerns regarding the use of RAAS inhibitors in patients with COVID-19. Some physicians have considered the need for interrupting RAAS inhibition in order to reduce the possibility of SA...
Source: Drugs and Aging - October 21, 2020 Category: Geriatrics Source Type: research

Can You Trust Your Gut? Implicating a Disrupted Intestinal Microbiome in the Progression of NAFLD/NASH
Non-alcoholic fatty liver disease (NAFLD) is a spectrum of disorders, ranging from fatty liver to a more insulin resistant, inflammatory and fibrotic state collectively termed non-alcoholic steatohepatitis (NASH). In the United States, 30%–40% of the adult population has fatty liver and 3%–12% has NASH, making it a major public health concern. Consumption of diets high in fat, obesity and Type II diabetes (T2D) are well-established risk factors; however, there is a growing body of literature suggesting a role for the gut microbiome in the development and progression of NAFLD. The gut microbiota is separated fro...
Source: Frontiers in Endocrinology - October 21, 2020 Category: Endocrinology Source Type: research

Sex-Specific Effect of High-Fat Diet on Glycerol Metabolism in Murine Adipose Tissue and Liver
In conclusion, no coordinated upregulation of glycerol channels in adipose tissue and liver was observed in response to HFD. The effect of HFD on glycerol metabolism is sex-specific in mice, and we propose that the increased AQP7 abundance in female adipose tissue could contribute to their less severe response to HFD. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - October 21, 2020 Category: Endocrinology Source Type: research

The Impact of Milk and Its Components on Epigenetic Programming of Immune Function in Early Life and Beyond: Implications for Allergy and Asthma
In this study, we focus on the effects of maternal nutrition during pregnancy, the effects of the bioactive components in human and bovine milk, and the environmental factors that can affect early life (i.e., farming, milk processing, and bacterial exposure), and which contribute to the epigenetic mechanisms underlying the persistent programming of immune functions and allergic diseases. This knowledge will help to improve approaches to nutrition in early life and help prevent allergies in the future. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - October 21, 2020 Category: Allergy & Immunology Source Type: research

The Relationship Between Vitamin D Deficiency and Glycated Hemoglobin Levels in Patients with Type 2 Diabetes Mellitus
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - October 20, 2020 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research

Sustained Stimulation of & beta;2AR Inhibits Insulin Signaling in H9C2 Cardiomyoblast Cells Through the PKA-Dependent Signaling Pathway
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - October 20, 2020 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research

Metformin Treatment: A Potential Cause of Megaloblastic Anemia in Patients with Type 2 Diabetes Mellitus
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - October 20, 2020 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research

Diabetes Mellitus and Tuberculosis Comorbidity and Associated Factors Among Bale Zone Health Institutions, Southeast Ethiopia
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - October 20, 2020 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research

Peer Influence on Obesity: Evidence from a Natural Experiment of a Gene-Environment Interaction
Publication date: Available online 20 October 2020Source: Social Science ResearchAuthor(s): Yi Li, Guang Guo (Source: Social Science Research)
Source: Social Science Research - October 20, 2020 Category: Psychiatry & Psychology Source Type: research

Impact of obesity with or without hypertension on systemic haemodynamic and renal responses to lower body negative pressure.
CONCLUSIONS: These results show that the systemic and the renal response to LBNP differ according to weight and to BP categories. Systolic BP and heart show a progressive increased response form healthy volunteers to OBN and then to obese hypertensive participants while urinary output and free water clearance responses are increased in OBN only, suggesting that the occurrence of hypertension in obese individuals modifies the early kidney responses to stress. CLINICALTRIAL.GOV IDENTIFIER: NCT01734096. PMID: 33073631 [PubMed - as supplied by publisher] (Source: Blood Pressure)
Source: Blood Pressure - October 20, 2020 Category: Hematology Tags: Blood Press Source Type: research

CT assessment of preoperative nutritional status in gastric cancer: Severe low skeletal muscle mass and obesity-related low skeletal muscle mass are unfavorable factors of postoperative complications.
CONCLUSIONS: LSMM was not significantly correlated with postoperative complications. Severe LSMM and obesity-related LSMM are unfavorable factors for postoperative complications with GC after gastrectomy. PMID: 33063547 [PubMed - as supplied by publisher] (Source: Expert Review of Gastroenterology and Hepatology)
Source: Expert Review of Gastroenterology and Hepatology - October 20, 2020 Category: Gastroenterology Tags: Expert Rev Gastroenterol Hepatol Source Type: research

Alcohol and hepatocarcinogenesis.
Authors: Taniai M Abstract An excessive alcohol intake may result in fatty liver, acute/chronic hepatitis, cirrhosis, and lead to hepatocellular carcinoma (HCC). The aim of this review is to clarify the present condition and the mechanisms of alcohol-related hepatocarcinogenesis and clinical risk factors for alcohol-related HCC. There are several possible mechanisms through which alcohol may induce hepatocarcinogenesis, including the mutagenic effects of acetaldehyde toxicity through the formation of protein and DNA adducts and the production of reactive oxygen species due to the excessive hepatic deposition of iro...
Source: Clinical and molecular hepatology - October 20, 2020 Category: Gastroenterology Tags: Clin Mol Hepatol Source Type: research

Metabolic Effects of Testosterone Replacement Therapy in Patients with Type 2 Diabetes Mellitus or Metabolic Syndrome: A Meta-Analysis.
Authors: Li SY, Zhao YL, Yang YF, Wang X, Nie M, Wu XY, Mao JF Abstract Background: Testosterone replacement therapy (TRT) is commonly used for the treatment of hypogonadism in men, which is often associated with type 2 diabetes mellitus (T2DM) and metabolic syndrome (Mets). Recent compiling evidence shows that TRT has beneficial metabolic effects on these patients. Objective: A meta-analysis has been conducted to evaluate the effects of TRT on cardiovascular metabolic factors. Methods: We conducted a systemic search on PubMed, Embase, Cochrane Library, Wanfang, and CNKI and selected randomized controlled t...
Source: International Journal of Endocrinology - October 20, 2020 Category: Endocrinology Tags: Int J Endocrinol Source Type: research

Comparing the Efficacy and Safety of Glucagon-Like Peptide 1 Receptor Agonists with Sodium-Glucose Cotransporter 2 Inhibitors for Obese Type 2 Diabetes Patients Uncontrolled on Metformin: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
Authors: Ding L, Sun B, Xiao X Abstract Introduction: To conduct the first meta-analysis of randomized controlled trials (RCTs) comparing glucagon-like peptide 1 receptor agonists (GLP-1RAs) with sodium-glucose cotransporter 2 inhibitors (SGLT-2is) for obese type 2 diabetes (T2D) patients uncontrolled on metformin. Methods: We searched Pubmed, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), Ovid, and Web of Science from inception to May 14, 2020, without language restrictions for eligible RCTs. The primary outcome is the mean change from baseline in glycated haemoglobin (HbA1c). Results: T...
Source: International Journal of Endocrinology - October 20, 2020 Category: Endocrinology Tags: Int J Endocrinol Source Type: research

Postural Stability in Obese Preoperative Bariatric Patients Using Static and Dynamic Evaluation
Conclusion: Importantly, these data highlight obesity ’s contribution towards increased postural instability. Obese subjects exhibited greater COP displacement at higher AP velocities versus nonobese subjects, suggesting that clinically obese individuals show greater instability than nonobese subjects. Identifying factors contributory to instability could encourage patient-specific physical therapies and presurgical measures to mitigate instability and monitor postsurgical balance improvements.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - October 20, 2020 Category: Eating Disorders & Weight Management Source Type: research

Erratum
Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - October 20, 2020 Category: Eating Disorders & Weight Management Source Type: research

Experience in the management of severe COVID-19 patients in an intensive care unit.
Conclusion: The characteristics of the critically ill patients in our hospital were mostly elderly and obese, with the variables of higher SOFA score and acute kidney injury associated with higher mortality. PMID: 33064694 [PubMed - in process] (Source: Cirugia y Cirujanos)
Source: Cirugia y Cirujanos - October 20, 2020 Category: Surgery Authors: Sosa-García JO, Gutiérrez-Villaseñor AO, García-Briones A, Romero-González JP, Juárez-Hernández E, González-Chon O Tags: Cir Cir Source Type: research

The colors of adipose tissue and the relationship with irisin.
s-Pantoja R Abstract Excess adipose tissue is considered one of the main causes of metabolic and cardiovascular diseases. Initially, the adipose tissue was considered the main lipid and energy storage of the organism. Subsequently it was discovered that adipose tissue had other functions such as endocrine, controlling different metabolic and immune processes. Currently, different types of adipose tissue are recognized. The white adipocyte represents the main energy reserve, on the contrary the brown adipocyte is responsible for the oxidation of lipids for thermogenesis. The beige adipocyte originates from the whit...
Source: Cirugia y Cirujanos - October 20, 2020 Category: Surgery Authors: Corina-Sosa B, Basurto L, Luqueño E, Robledo A, Mendieta-Zerón H, Oros-Pantoja R Tags: Cir Cir Source Type: research

Genome-Wide Regulation of Electroacupuncture and Treadmill Exercise on Diet-Induced Obese Rats.
This study is the first to compare and analyze the differences in gene expression profiles in the retro-WAT of rats in different groups, which provide a clue for further investigation into the molecular mechanisms of obesity treatment by EA and TE. PMID: 33062027 [PubMed] (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - October 20, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Study on the Intervention Effect of Qi Gong Wan Prescription on Patients with Phlegm-Dampness Syndrome of Polycystic Ovary Syndrome Based on Intestinal Flora.
Conclusions: Intestinal flora imbalance is a key factor in the pathogenesis of PCOS with phlegm-dampness syndrome. Besides, Jiawei Qi Gong Wan improves insulin resistance which is linked to the status of the intestinal flora in PCOS patients with phlegm-dampness syndrome. PMID: 33062017 [PubMed] (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - October 20, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

The Beneficial Effect of Traditional Chinese Exercises on the Management of Obesity.
Authors: Qin Y, Xia W, Huang W, Zhang J, Zhao Y, Fang M Abstract This paper systematically reviewed the clinical update of traditional Chinese exercises in the treatment of simple obesity in recent years and discussed their specific advantages in this aspect. This review focused on several typical traditional Chinese exercises, namely, Tai Chi, Ba Duan Jin, Yi Jin Jing, Wu Qin Xi, Shaolin Neigong, and Liu Zi Jue, which all showed clinical beneficial effect on the treatment of simple obesity with their own characteristics. To optimize the clinical therapeutic effect of these traditional Chinese exercises, we need to...
Source: Evidence-based Complementary and Alternative Medicine - October 20, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Lipoprotein and Metabolic Profiles Indicate Similar Cardiovascular Risk of Liver Steatosis and NASH
Conclusion: We show in this study that cholesterol profiles, apolipoproteins, and amino acids could function as a potential noninvasive test to screen for NAFLD or even NASH in larger populations. However, few differences in cholesterol profiles were identified between the NAFL and NASH groups, indicating similar cardiovascular risk profiles.Digestion (Source: Digestion)
Source: Digestion - October 20, 2020 Category: Gastroenterology Source Type: research

Omitting Lymphadenectomy in Obese Endometrial Cancer Patients Undergoing Sentinel Lymph Node Mapping: More Is Less
To evaluate the feasibility of sentinel lymph node (SLN) mapping in obese endometrial cancer patients. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 20, 2020 Category: OBGYN Authors: L. Kogan, E. Matanes, M. Wissing, C. Mitric, S. Lau, S. Salvador, W.H. Gotlieb Source Type: research

Does Obesity and Procedure Type Increase the Risk of in-Hospital Mortality in Laparoscopic Hysterectomy?
To assess the differences in demographics and laparoscopic hysterectomy type by comorbid obesity and to assess the risk of in-hospital mortality due to obesity and other comorbidities. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 20, 2020 Category: OBGYN Authors: C.A. Robert, R.S. Patel Source Type: research

Association between Obesity and Surgical Outcomes for Minimally Invasive Hysterectomy
To investigate the morbidity associated with minimal invasive hysterectomy in obese women. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 20, 2020 Category: OBGYN Authors: R.J. Jalloul, O.L. Dziadek, M.F. Bartal Tags: Open Communications 21: Laparoscopy (4:00 PM — 5:00 PM)4:24 PM Source Type: research

Liver Laceration with Palmer's Point Entry in the Super Obese Patient
The purpose of this video is to present an uncommon liver laceration complication with Palmer's Point entry and describe considerations for laparoscopic entry in the obese patient. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 20, 2020 Category: OBGYN Authors: A.S. Womack, J. Mourad Tags: Open Communications 16: Laparoscopy (3:00 PM — 4:00 PM) 3:00 PM Source Type: research

Trends in Complications Among Benign Hysterectomy Patients in Relation to BMI
To evaluate complication rates and length of stay over time in relation to BMI to assess for improvements in care given the increasing need to take care of obese women. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 20, 2020 Category: OBGYN Authors: C. Gnade, M.L. Haugsdal, C. Wu, P.Ten Eyck, B. Van Voorhis Source Type: research

Change of respiratory functions, the STOP-Bang questionnaire, and Epworth sleepiness scale after bariatric surgery.
CONCLUSION: We showed that FVC and FEV1 increased in the short and long term after weight loss by bariatric surgery; we also found that STOP-Bang questionnaire and Epworth sleepiness scale scores decreased postoperatively. These tests may be helpful to assess OSAS risk before and after surgery. KEY WORDS: Bariatric surgery, Obesity, Respiratory functions, STOP-Bang questionnaire and Epworth sleepiness test. PMID: 33055387 [PubMed - as supplied by publisher] (Source: Annali Italiani di Chirurgia)
Source: Annali Italiani di Chirurgia - October 20, 2020 Category: Surgery Tags: Ann Ital Chir Source Type: research

GSE159612 Obesity in cardiac surgery patients
We report on the application of RNA sequencing to study expression changes in cardiac surgery patients of different obesity categories. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - October 20, 2020 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research

Stepwise Laparoendoscopic Single-Site Pectopexy for Pelvic Organ Prolapse
Study Objective: To demonstrate stepwise techniques for the successful utilization of the LESS technique for safely performing pectopexy.Design: Stepwise demonstration with narrated video footage (Canadian Task Force classification III).Setting: An academic tertiary care hospital.Patient: A 48-year-old G2P2, NSVDx2 with Stage III anterior vaginal prolapse, Stage III uterine prolapse& posterior vaginal prolapse. The preoperative vaginal length was 6 cm.Interventions: Laparoscopic sacrocolpopexy is the current gold standard for pelvic organ prolapse demonstrating a low recurrence rate; however, it can be technically chal...
Source: The Journal of Minimally Invasive Gynecology - October 20, 2020 Category: OBGYN Authors: Qianqing Wang, Zhenkun Guan, Xiangcui Guo, Beibei Chen, Li Li, Juan Liu, Xiaoming Guan Tags: Video Article Source Type: research

Impact of obesity, fasting plasma glucose level, blood pressure, and renal function on the severity of COVID-19: a matter of sexual dimorphism?
This study aimed to assess whether body mass index (BMI), fasting plasma glucose (FPG) levels, blood pressure (BP), and kidney function were associated with the risk of severe disease or death in patients with COVID-19. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - October 20, 2020 Category: Endocrinology Authors: Kyungmin Huh, Rugyeom Lee, Wonjun Ji, Minsun Kang, In Cheol Hwang, Dae Ho Lee, Jaehun Jung Source Type: research

Normal weight obesity and COVID-19 severity: A poorly recognized link
People with obesity (those with high body mass index (BMI)) and coronavirus disease 2019 (COVID-19) are at increased risk of requiring intensive care admission and mechanical ventilation, and death [1]. Although BMI is a commonly used measure of obesity in clinical settings, it cannot delineate fat-free mass from adipose tissue [2]. Thus, people with normal weight on the BMI scale can have elevated body fat percent, particularly in the visceral area, an entity called normal weight obesity (NWO) [2, 3]. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - October 20, 2020 Category: Endocrinology Authors: Thirunavukkarasu Sathish, Nitin Kapoor Tags: Letter to the Editor Source Type: research

COVID ‐19: Impact of obesity and diabetes on disease severity
This study investigated the potential associations of obesity and diabetes with COVID‐19 severe outcomes, assessed as ICU admittance. Medical hi story, demographic and patient characteristics of a retrospective cohort (1158 patients) hospitalized with COVID‐19 were analysed at a single centre in Kuwait. Univariate and multivariate analyses were performed to explore the associations between different variables and ICU admittance. Of 1158 ho spitalized patients, 271 had diabetes, 236 had hypertension and 104 required admittance into the ICU. From patients with available measurements, 157 had body mass index (BMI) ≥25&...
Source: Clinical Obesity - October 20, 2020 Category: Eating Disorders & Weight Management Authors: Salman Al ‐Sabah, Mohannad Al‐Haddad, Sarah Al‐Youha, Mohammad Jamal, Sulaiman Almazeedi Tags: Original Research Article Source Type: research

The Beneficial Effects of Apical Sodium ‐Dependent Bile Acid Transporter Inactivation Depend on Dietary Fat Composition
ConclusionsThe beneficial metabolic effects of ASBT inactivation on diet ‐induced obesity depend on decreased intestinal absorption of SFAs, and thus on the dietary fatty acid composition. These findings highlight the importance of dietary fatty acid composition in the therapeutic effects of ASBT inhibition.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - October 20, 2020 Category: Food Science Authors: Ivo P. Peppel, Anuradha Rao, Marleen B. Dommerholt, Laura Bongiovanni, Rachel Thomas, Alain Bruin, Saul J. Karpen, Paul A. Dawson, Henkjan J. Verkade, Johan W. Jonker Tags: Research Article Source Type: research

IJERPH, Vol. 17, Pages 7658: Association between Neighborhood Food Environment and Body Mass Index among Older Adults in Beijing, China: A Cross-Sectional Study
Conclusion: Although we found some significant associations between the neighborhood food environment and obesity, the current results are not strong enough to draw specific conclusions. Policymakers will need to rely on more evidence to derive concrete policy recommendations. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - October 20, 2020 Category: Environmental Health Authors: Zhang Guo Zhang He Zhang Zhou Zhang Li Ma Tags: Article Source Type: research

IJERPH, Vol. 17, Pages 7644: Long-Term Weight Loss Results, Remission of Comorbidities and Nutritional Deficiencies of Sleeve Gastrectomy (SG), Roux-En-Y Gastric Bypass (RYGB) and One-Anastomosis Gastric Bypass (OAGB) on Type 2 Diabetic (T2D) Patients
Conclusion: OAGB obtained greater weight loss and remission of dyslipidemia than RYGB or SG. Excluding lower iron deficiency rates after SG, there were no significant differences in the development of nutritional deficiencies between groups. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - October 20, 2020 Category: Environmental Health Authors: Maria-Jose Castro Jose-Maria Jimenez Miguel-Angel Carbajo Maria Lopez Maria-Jose Cao Sara Garcia Jaime Ruiz-Tovar Tags: Article Source Type: research

Fecal transplantation and butyrate improve neuropathic pain, modify immune cell profile, and gene expression in the PNS of obese mice [Physiology]
Obesity affects over 2 billion people worldwide and is accompanied by peripheral neuropathy (PN) and an associated poorer quality of life. Despite high prevalence, the molecular mechanisms underlying the painful manifestations of PN are poorly understood, and therapies are restricted to use of painkillers or other drugs that do not... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - October 20, 2020 Category: Science Authors: Raiza R. Bonomo, Tyler M. Cook, Chaitanya K. Gavini, Chelsea R. White, Jacob R. Jones, Elisa Bovo, Aleksey V. Zima, Isabelle A. Brown, Lara R. Dugas, Eleonora Zakharian, Gregory Aubert, Francis Alonzo III, Nigel A. Calcutt, Virginie Mansuy-Aubert Tags: Biological Sciences Source Type: research

Prevalence of osteosarcopenic obesity in community-dwelling older adults: a cross-sectional retrospective study
AbstractSummaryIn our study investigating the prevalence of osteosarcopenic obesity (OSO) in community-dwelling older adults and possible factors responsible for falls, we have found that prevalence of OSO is 10.7%. OSO does not significantly increase the odds of falling, whereas lower handgrip strength, ALMi and gait speed were independent factors associated with falls.PurposesThe purposes of the study were (a) to determine the prevalence of osteosarcopenic obesity (OSO) in community-dwelling older adults and (b) to investigate the association between falls and possible factors in individuals with and without OSO.MethodsM...
Source: Archives of Orthopaedic and Trauma Surgery - October 20, 2020 Category: Orthopaedics Source Type: research