Bridging the Gap: Addressing Immigrant Health Through Community-initiated Screening Events
CONCLUSIONS: Working directly with the community, we designed and implemented health prevention events which served to meet a growing need and to identify and address health concerns among the Hispanic immigrant community.PMID:38661823 (Source: Progress in Community Health Partnerships)
Source: Progress in Community Health Partnerships - April 25, 2024 Category: International Medicine & Public Health Authors: Sally Moyce Nathaniel Sisson Madeline Metcalf Source Type: research
Developing the Feast for the Future Program through a Community Visioning Process
CONCLUSIONS: A community-based participatory action research (CBPAR) process was critical to developing a culturally appropriate program that built on community strengths.PMID:38661833 (Source: Progress in Community Health Partnerships)
Source: Progress in Community Health Partnerships - April 25, 2024 Category: International Medicine & Public Health Authors: Kristen Speakman Nicole Neault Ventura Lovato Katie Cueva Ivanka Szabo Rebecca Wallis Jennifer Richards Allison Barlow Source Type: research
Novel subtype of obesity influencing the outcomes of sleeve gastrectomy: Familial aggregation of obesity
CONCLUSION: FAO patients is associated with decreased mid-to-long-term weight loss outcomes; the alleviation of T2DM, hyperlipidemia and NAFLD; and decreased incidence of acid reflux postoperatively.PMID:38659480 | PMC:PMC11036498 | DOI:10.3748/wjg.v30.i13.1887 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 25, 2024 Category: Gastroenterology Authors: Ze-Yu Wang Yun-Fei Qu Tian-Ming Yu Zeng-Lin Liu Yu-Gang Cheng Ming-Wei Zhong San-Yuan Hu Source Type: research
Macrophage polarization: an important role in inflammatory diseases
Front Immunol. 2024 Apr 10;15:1352946. doi: 10.3389/fimmu.2024.1352946. eCollection 2024.ABSTRACTMacrophages are crucial cells in the human body's innate immunity and are engaged in a variety of non-inflammatory reactions. Macrophages can develop into two kinds when stimulated by distinct internal environments: pro-inflammatory M1-like macrophages and anti-inflammatory M2-type macrophages. During inflammation, the two kinds of macrophages are activated alternatively, and maintaining a reasonably steady ratio is critical for maintaining homeostasis in vivo. M1 macrophages can induce inflammation, but M2 macrophages suppress...
Source: Atherosclerosis - April 25, 2024 Category: Cardiology Authors: Min Luo Fukun Zhao Huan Cheng Mu Su Yuanmin Wang Source Type: research
Association of leptin receptor polymorphisms with susceptibility of non-small cell lung cancer: Evidence from 2249 subjects
This study highlights that LEPR rs6588147, rs1137101 genotypes and LEPR Ars1037100Ars1037101Ars6588147 haplotype are correlated with the occurrence of NSCLC. LEPR rs1137100 G>A SNP increases the risk of lymph node metastases.PMID:38659416 | DOI:10.1002/cam4.7178 (Source: Cancer Control)
Source: Cancer Control - April 25, 2024 Category: Cancer & Oncology Authors: Weifeng Tang Jian Wang Ting Dai Hao Qiu Chao Liu Shuchen Chen Zhendong Hu Source Type: research
Prediction of resting energy expenditure for adolescents with severe obesity: A multi ‐centre analysis
ConclusionThis new equation provides an updated REE prediction that accounts for severe obesity and metabolic complications frequently observed in contemporary youth. (Source: Pediatric Obesity)
Source: Pediatric Obesity - April 25, 2024 Category: Eating Disorders & Weight Management Authors: Amy A. Rydin,
Cameron Severn,
Laura Pyle,
Nazeen Morelli,
Ashley H. Shoemaker,
Stephanie T. Chung,
Jack A. Yanovski,
Joan C. Han,
Janine A. Higgins,
Kristen J. Nadeau,
Claudia Fox,
Aaron S. Kelly,
Melanie G. Cree Tags: ORIGINAL RESEARCH Source Type: research
A service evaluation of more than 1 million self ‐funding adults attending a community weight management programme
SummaryScaled interventions are required to address levels of overweight and obesity and reduce health inequalities. Little data is available on the effectiveness of community weight management programmes for participants self-selecting to attend across different socio-economic backgrounds. This analysis investigates 3, 6, and 12-month outcomes of adults joining a real-life community weight management programme. Weight, attendance and Indices of Multiple Deprivation (IMD) data from all fee-paying adults joining Slimming World in 2016 were collated. Data were analysed using descriptive and inferential statistics to determin...
Source: Clinical Obesity - April 25, 2024 Category: Eating Disorders & Weight Management Authors: Josef Toon,
Sarah ‐Elizabeth Bennett,
Jacquie Lavin,
Carolyn Pallister,
Amanda Avery Tags: ORIGINAL RESEARCH Source Type: research
Association of leptin receptor polymorphisms with susceptibility of non ‐small cell lung cancer: Evidence from 2249 subjects
This study highlights thatLEPR rs6588147, rs1137101 genotypes andLEPR Ars1037100Ars1037101Ars6588147 haplotype are correlated with the occurrence of NSCLC.LEPR rs1137100 G>A SNP increases the risk of lymph node metastases. (Source: Cancer Medicine)
Source: Cancer Medicine - April 25, 2024 Category: Cancer & Oncology Authors: Weifeng Tang,
Jian Wang,
Ting Dai,
Hao Qiu,
Chao Liu,
Shuchen Chen,
Zhendong Hu Tags: REVIEW Source Type: research
Identifying latent genetic interactions in genome-wide association studies using multiple traits
AbstractThe"missing" heritability of complex traits may be partly explained by genetic variants interacting with other genes or environments that are difficult to specify, observe, and detect. We propose a new kernel-based method called Latent Interaction Testing (LIT) to screen for genetic interactions that leverages pleiotropy from multiple related traits without requiring the interacting variable to be specified or observed. Using simulated data, we demonstrate that LIT increases power to detect latent genetic interactions compared to univariate methods. We then apply LIT to obesity-related traits in the UK Bi...
Source: Genome Medicine - April 25, 2024 Category: Genetics & Stem Cells Source Type: research
Your diet may influence how effective vaccines are for you
Obese mice that lost weight on a low-fat diet before getting a flu shot had better immune responses than those that lost weight afterwards, suggesting diet and weight loss influence vaccine efficacy (Source: New Scientist - Health)
Source: New Scientist - Health - April 24, 2024 Category: Consumer Health News Source Type: research
Association between lipoprotein(a) and cardiovascular disease in patients undergoing coronary angiography
CONCLUSION: The findings indicated that elevated lipoprotein(a) had no obvious relationship with hypertension and obesity. Elevated lipoprotein(a) increases the risk of high total cholesterol, high LDL‑c, and premature CAD, and increases the occurrence and severity of coronary heart disease.PMID:38658408 | DOI:10.1007/s00059-024-05247-0 (Source: Herz)
Source: Herz - April 24, 2024 Category: Cardiology Authors: Azhi ShaMa Chunmei Xu Yingying Huang Chunlan Ma Jingyue Hu Zhuxin Li Chunyu Zeng Source Type: research
Blood Pressure Control and Associated Factors among Hypertension Comorbid Type 2 Diabetic Patients in Southeast Ethiopia
CONCLUSION: Uncontrolled hypertension was found to be high among hypertension comorbid type 2 diabetic patients. Patients' adherence to antihypertensive medication, physical activity, and alcohol abstinence should be maximized. Loss of weight is also crucial, as is the early detection and management of comorbidities.PMID:38655153 | PMC:PMC11039015 | DOI:10.1155/2024/6668436 (Source: International Journal of Hypertension)
Source: International Journal of Hypertension - April 24, 2024 Category: Cardiology Authors: Fikreab Desta Selamawit Mengesha Fanuel Belayneh Demelash Woldeyohannes Yohannes Tekalegn Demisu Zenbaba Biniyam Sahiledengle Dejene Hailu Source Type: research
The efficacy and safety of GLP-1 receptor agonists in youth with type 2 diabetes: a meta-analysis
CONCLUSIONS: Within this specific population, GLP-1 RAs exhibit a notable association with substantial reductions in HbA1c, FBG, and body weight. The administration of these medications is concurrent with an elevated incidence of side effects, which are predominantly gastrointestinal and tolerable.TRIAL REGISTRATION: PROSPERO identifier: CRD42023393020.PMID:38659064 | DOI:10.1186/s13098-024-01337-5 (Source: Atherosclerosis)
Source: Atherosclerosis - April 24, 2024 Category: Cardiology Authors: Louise Buonalumi Tacito Yugar Luis Gustavo Sedenho-Prado Isadora Maria Castilho da Silva Ferreira Cleide Aparecida Moreira Silva Andrei C Sposito Cintia Cercato Source Type: research
Tolypocladium sinense Mycelium Polysaccharide Alleviates Obesity, Lipid Metabolism Disorder, and Inflammation Caused by High Fat Diet via Improving Intestinal Barrier and Modulating Gut Microbiota
ConclusionThe findings show that TSMP can inhibit obesity and alleviates obesity-related lipid metabolism disorders, inflammatory responses, and oxidative stress by modulating the gut microbiota and improving intestinal barrier. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - April 24, 2024 Category: Food Science Authors: Mingjian Bai,
Xiaolong Wang,
Dongyang Liu,
Aofeng Xu,
Hao Cheng,
Lin Li,
Chunjing Zhang Tags: Research Article Source Type: research
GSE244359 Skeletal muscle methylation signatures of obese high- and low- responders to endurance exercise training
Contributors : Annette Sch ürmann ; Cora Weigert ; Andreas Birkenfeld ; Andreas Peter ; Martin Hrabe de Angelis ; Johannes Beckers ; Markus Jähnert ; Martin Irmler ; Meriem Ouni ; Thomas Goj ; Leona KovacSeries Type : Methylation profiling by arrayOrganism : Homo sapiensThe participants performed 8 weeks of superised aerobic endurance exercise. Skeletal muscle biopsise were taken at rest before and after intervention and matched analysis was performed. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - April 24, 2024 Category: Genetics & Stem Cells Tags: Methylation profiling by array Homo sapiens Source Type: research
