Cardiovascular evaluation in advanced chronic kidney disease
Herz. 2021 Mar 2. doi: 10.1007/s00059-021-05028-z. Online ahead of print.ABSTRACTPatients with chronic kidney disease (CKD) display an increased cardiovascular comorbidity, which is often underdiagnosed. Thus, effective cardiovascular diagnostic testing is of particular importance for this group of patients. Data from prospective randomized trials with cardiovascular diagnostic testing in CKD patients and improved outcome are limited. Diagnostic stress testing for CKD patients requires special consideration. Guidelines recommend cardiovascular diagnostic testing for patients undergoing an evaluation before transplantation....
Source: Herz - March 2, 2021 Category: Cardiology Authors: Georg Schlieper Source Type: research

Role of IL-9, IL-2RA, and IL-2RB genetic polymorphisms in coronary heart disease
This study aimed to detect the potential association between interleukin (IL)-9, IL-2RA, and IL-2RB variants and CHD in a Han Chinese population.METHODS: This case-control study included 499 CHD patients and 496 healthy controls. Seven single-nucleotide polymorphisms (SNPs) were genotyped to investigate the possible association between the polymorphisms and CHD risk. Interactions between SNPs and CHD risk were analyzed via multifactor dimensionality reduction (MDR).RESULTS: We observed an association between IL‑9 rs55692658 (OR = 1.72, p = 0.003) and increased CHD risk. Age-stratified analysis indicated that regardless o...
Source: Herz - March 2, 2021 Category: Cardiology Authors: Xianghong Chen Xingfan Wang Zaozhang Zhang Yuewu Chen Chao Wang Source Type: research

[Diagnosis and treatment of acute ischemic insults].
Authors: Diener HC, Wachter R Abstract In cases of stroke a distinction is made between a transient ischemic attack (TIA), a manifest ischemic infarction and cerebral hemorrhage. Cerebral ischemia can be caused by large vessel disease, small vessel disease, embolic causes, rare causes or stroke of unknown etiology. Acute diagnostic tests include a neurological examination, computed tomography (CT) and/or magnetic resonance imaging (MRI) with angiography, electrocardiography (ECG), and laboratory tests. The basic treatment of patients with TIA or acute ischemic infarction is performed in the stroke unit and inc...
Source: Herz - February 21, 2021 Category: Cardiology Tags: Herz Source Type: research

Gender and career in cardiology-a  cross-sectional study.
CONCLUSION: Further development of the work culture in cardiology seems necessary. In order to increase the attractiveness of the field overall and to provide equal opportunities in cardiology, more targeted support should be provided to young doctors and more flexibility introduced into work. PMID: 33599803 [PubMed - as supplied by publisher] (Source: Herz)
Source: Herz - February 21, 2021 Category: Cardiology Tags: Herz Source Type: research

[COVID-19 pandemic : Effects on clinical care of cardiovascular patients in spring 2020].
Authors: Zeymer U, Gitt A, Thiele H Abstract The coronavirus disease 2019 (COVID-19) pandemic has led to a focus of acute medical care on the treatment of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and pneumonia with consequences for all other medical specialties. Between March and May 2020 a decline in the number of admissions for elective cardiac procedures as well as for cardiac emergencies was observed. The number of patients hospitalized for acute myocardial infarction decreased, especially those with non-ST elevation myocardial infarction (NSTEMI), while ti...
Source: Herz - February 18, 2021 Category: Cardiology Tags: Herz Source Type: research

Heart failure in advanced chronic kidney disease: treatment rationale.
Authors: Marx N, Floege J Abstract Patients with chronic kidney disease (CKD) exhibit an increased risk to develop heart failure and the presence of heart failure in patients with CKD leads to a worse prognosis. The following overview article summarizes the current standard of medical heart failure therapy and discusses the treatment characteristics in patients with CKD. PMID: 33564918 [PubMed - as supplied by publisher] (Source: Herz)
Source: Herz - February 12, 2021 Category: Cardiology Tags: Herz Source Type: research

Treatment rationale for coronary heart disease in advanced CKD.
Authors: Lopau K, Wanner C Abstract Chronic kidney disease (CKD) is accompanied by coronary artery disease (CAD) in most patients. In this article we describe differences in the pathogenesis, diagnosis, and treatment of CAD compared with patients without kidney impairment. The histological phenotype as well as the clinical presentation of acute and chronic coronary syndromes differ from those of patients with normal kidney function. The risk of cardiovascular events including death is strikingly increased with higher stages of CKD. Traditional but even more nontraditional cardiovascular risk factors are contributin...
Source: Herz - February 12, 2021 Category: Cardiology Tags: Herz Source Type: research

Heart and brain interactions : Pathophysiology and management of cardio-psycho-neurological disorders.
Authors: Schnabel RB, Hasenfuß G, Buchmann S, Kahl KG, Aeschbacher S, Osswald S, Angermann CE Abstract Cardiovascular diseases (CVD) and mental health disorders (MHD; e.g. depression, anxiety and cognitive dysfunction) are highly prevalent and are associated with significant morbidity and mortality and impaired quality of life. Currently, possible interactions between pathophysiological mechanisms in MHD and CVD are rarely considered during the diagnostic work-up, prognostic assessment and treatment planning in patients with CVD, and research addressing bidirectional disease mechanisms in a systematic fa...
Source: Herz - February 7, 2021 Category: Cardiology Tags: Herz Source Type: research

Obesity paradox in pulmonary hypertension due to left ventricular systolic dysfunction.
In this study, we explored the risk factors for PH-HFrEF and investigated the related factors affecting the prognosis of PH-HFrEF patients. METHODS: The study recruited consecutive patients with PH-HFrEF and systolic pulmonary artery pressure (sPAP) of more than 40 mm Hg with left ventricular ejection fraction (LVEF) of less than 45% on echocardiography. Patients with left ventricular systolic dysfunction (HFrEF) but without PH (sPAP 
Source: Herz - February 7, 2021 Category: Cardiology Tags: Herz Source Type: research

[Cardiology: overcome boundaries, discover new worlds].
Authors: Hilfiker-Kleiner D, Thiele H PMID: 33512533 [PubMed - as supplied by publisher] (Source: Herz)
Source: Herz - January 30, 2021 Category: Cardiology Tags: Herz Source Type: research

Favorable electrocardiographic changes after substantial weight loss in patients with morbid obesity : Results of a  prospective study.
This study aimed to determine whether weight loss by bariatric surgery has an effect on arrhythmia-related electrocardiographic (ECG) variables in morbidly obese patients. METHODS: In this prospective study, the data of 48 patients were analyzed. All ECG variables that have the potential to predict ventricular arrhythmia were evaluated before surgery, and were compared with the 1‑month and 6‑month follow-up results. RESULTS: The mean body mass index was 45.74 ± 5.60 kg/m2 before surgery. There was a statistically significant decline in body mass index in the first and sixth month aft...
Source: Herz - January 29, 2021 Category: Cardiology Tags: Herz Source Type: research

Neglected cardiovascular diseases and their significance in the Global North.
Authors: Viljoen CA, Hoevelmann J, Muller E, Sliwa K Abstract Due to increasing global migration, the spectrum of cardiovascular disease (CVD) is changing in developed countries. Up to 3% of migrants arriving in Europe have underlying CVD. Despite their high global prevalence, conditions such as rheumatic heart disease, Chagas disease, endomyocardial fibrosis, tuberculous pericarditis, peripartum cardiomyopathy, and pulmonary hypertension are often under-recognized, and, as a result, neglected in industrialized countries. Many of these conditions, and their causes, are often unfamiliar to the health-care provi...
Source: Herz - January 29, 2021 Category: Cardiology Tags: Herz Source Type: research

[Air pollution and cardiovascular diseases].
Authors: Münzel T, Hahad O, Daiber A, Lelieveld J Abstract Air pollution in the environment and in households is responsible worldwide for almost 9 million preventable premature deaths per year and almost 800,000 such deaths within Europe. Air pollution therefore shortens life expectancy worldwide by almost 3 years. Smoking, a proven cardiovascular risk factor, shortens the mean life expectancy by 2.2 years. Epidemiological studies have shown that air pollution from fine and coarse particulate matter is associated with increased cardiovascular morbidity and mortality. Responsible for this are ma...
Source: Herz - January 20, 2021 Category: Cardiology Tags: Herz Source Type: research

Predictors of adequate intraprocedural premature ventricular complex (PVC) frequency during idiopathic PVC ablation.
CONCLUSION: The 24 h PVC burden was the only predictor of adequate intraprocedural PVC frequency permitting activation mapping during idiopathic PVC ablation. PMID: 33464357 [PubMed - as supplied by publisher] (Source: Herz)
Source: Herz - January 20, 2021 Category: Cardiology Tags: Herz Source Type: research

[Personalized treatment concepts for arterial hypertension].
Authors: Lechner K, Schunkert H Abstract Arterial hypertension is the most important risk factor for cardiovascular diseases. Arterial hypertension is diagnosed when reproducible office resting blood pressure values are 140 mm Hg or more systolic and/or 90 mm Hg or more diastolic. A recent alternative is to base the diagnosis of hypertension on ambulatory 24 h blood pressure monitoring (ABPM) and/or home blood pressure monitoring (HBPM) if feasible. Nonpharmacological and pharmacological strategies of blood pressure management are available. Treatment decisions should involve a shared decision-making...
Source: Herz - January 13, 2021 Category: Cardiology Tags: Herz Source Type: research

Evaluation of the relationship between COVID-19 pneumonia severity and pulmonary artery diameter measurement.
Authors: Yildiz M, Yadigar S, Yildiz BŞ, Aladag NB, Keskin O, Ozer RS, Topel C, Kahraman S Abstract The goal of the present work was to examine associations between COVID-19 pneumonia severity and pulmonary artery diameter. A total of 101 patients with COVID-19 were included in this retrospective observational study. The patients were divided into three groups based on the CT images: 41 patients with mild pneumonia, group 2 had 39 patients with moderate pneumonia, and group 3 had 21 patients with severe pneumonia. Furthermore, the diameter of the main pulmonary artery was calculated a...
Source: Herz - January 13, 2021 Category: Cardiology Tags: Herz Source Type: research

[Cardiovascular diseases and COVID-19 : Pathophysiology, complications and treatment].
Authors: Schieffer E, Schieffer B, Hilfiker-Kleiner D Abstract The coronavirus disease 2019 (COVID-19) pandemic is a challenge for our healthcare system but at the same time is one of the excellent catalyzers and promoters of successful translational research. The COVID-19 is not only a simple viral infection of the bronchial system but is also a pandemic hyperinflammatory multiorgan disease. The cardiovascular system plays a causal role in this context, as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) invades host cells via the angiotensin-converting enzyme 2 (ACE-2), an enzyme in the...
Source: Herz - January 6, 2021 Category: Cardiology Tags: Herz Source Type: research

Valvular heart disease in patients with chronic kidney disease.
Authors: Hoevelmann J, Mahfoud F, Lauder L, Scheller B, Böhm M, Ewen S Abstract Valvular heart disease (VHD) is common in patients with impaired renal function, especially in those with end-stage renal disease (ESRD) undergoing dialysis. Progressive sclerosis and calcification of the valves and valvular annuli are major components of the etiology. These processes typically affect the aortic and mitral valve and can lead to both valvular insufficiency and stenosis. As recommended by the 2017 ESC/EACTS Guidelines for the management of VHD, surgical treatment remains the standard care for most cases of severe VHD...
Source: Herz - January 6, 2021 Category: Cardiology Tags: Herz Source Type: research

Heart and kidney disease: a  cardiovascular high-risk constellation.
Heart and kidney disease: a cardiovascular high-risk constellation. Herz. 2020 Dec 30;: Authors: Schunk SJ, Speer T, Fliser D Abstract Chronic kidney disease (CKD) is associated with substantial cardiovascular morbidity and mortality. This is mediated by highly prevalent traditional cardiovascular risk factors such as arterial hypertension and diabetes mellitus in patients with CKD, but also by the presence of CKD-specific so-called nontraditional cardiovascular risk factors such as vascular calcification, uremic toxins, uremic dyslipidemia, inflammation, and oxidative stress. Therefore, the prima...
Source: Herz - December 31, 2020 Category: Cardiology Tags: Herz Source Type: research

[ESC guidelines on sports cardiology 2020 : Which sports can be performed with heart diseases?]
Authors: Halle M, Niebauer J Abstract The guidelines for sports cardiology have recently been published for the first time by the European Society of Cardiology (ESC). They address recommendations for leisure time exercise and competitive sports in athletes with cardiovascular diseases. The spectrum ranges from women during pregnancy, athletes with increased cardiovascular risk and risk factors or with a genetic predisposition, such as ion channelopathies, cardiomyopathies, congenital heart diseases as well as patients with valvular heart diseases, coronary heart disease, after myocardial infarction, with arrhythmi...
Source: Herz - December 20, 2020 Category: Cardiology Tags: Herz Source Type: research

[2020 ESC guidelines in the shadow of the COVID-19 pandemic].
Authors: Dörr R, Maisch B PMID: 33319312 [PubMed - as supplied by publisher] (Source: Herz)
Source: Herz - December 17, 2020 Category: Cardiology Tags: Herz Source Type: research

[The ESC recommendations for COVID-19-no guideline, but a learning guidance].
Authors: Maisch B Abstract "Not a guideline but a guidance" is the motto of this document of guidance by the European Society of Cardiology, which is designed as an orientation aid to learning for physicians in the coronavirus disease 2019 (COVID-19) pandemic. A total of 62 European cardiologists as authors and 29 further experts as reviewers have contributed to this 119-page document. The emphasis of the guidelines is on a cautious strategy in dealing with a pandemic, which is still characterized by many unknown factors. It is consciously limited to cardiovascular diseases. In the last update f...
Source: Herz - December 16, 2020 Category: Cardiology Tags: Herz Source Type: research

[2020 ESC guidelines on atrial fibrillation : Summary of the most relevant recommendations and innovations].
Authors: Sepehri Shamloo A, Dagres N, Hindricks G Abstract The new guidelines for the diagnosis and management of atrial fibrillation (AF) were published by the European Society of Cardiology (ESC) in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS) in August 2020. The 2020 guidelines of the ESC on AF summarize the current developments in this field and provide general recommendations for the management of patients with AF based on the principles of evidence-based medicine. Beside the general statements on definition, epidemiology and clinical features of AF, interesting new aspects i...
Source: Herz - December 10, 2020 Category: Cardiology Tags: Herz Source Type: research

"Virtual" heart team through a  secure instant messenger smartphone app.
"Virtual" heart team through a secure instant messenger smartphone app. Herz. 2020 Dec 09;: Authors: Eggebrecht H, Schönburg M, Voigtländer T, Szalay Z, Chun J, Choi YH, Schmermund A PMID: 33296006 [PubMed - as supplied by publisher] (Source: Herz)
Source: Herz - December 10, 2020 Category: Cardiology Tags: Herz Source Type: research

[2020 ESC guidelines on treatment of adult congenital heart disease (ACHD)].
Authors: Ruperti-Repilado FJ, Thomet C, Schwerzmann M Abstract The new guidelines of the European Society of Cardiology (ESC) on treatment of adult congenital heart disease (ACHD) were published in August 2020. The previous recommendations from 2010 were adapted to reflect the diagnostic and therapeutic progress made in the past 10 years. The recommendations are nearly exclusively based on an evidence level C (consensus of opinion of experts or knowledge from small studies, retrospective studies or registries). This is not surprising considering the heterogeneous patient population with a multitude of car...
Source: Herz - December 3, 2020 Category: Cardiology Tags: Herz Source Type: research

NOD2 induces VCAM-1 and ET-1 gene expression via NF- κB in human umbilical vein endothelial cells with muramyl dipeptide stimulation.
CONCLUSION: Collectively, we confirmed NOD2 aggravated VCAM‑1 and ET‑1 gene expression through NF-κB in HUVECs treated with MDP. PMID: 33245410 [PubMed - as supplied by publisher] (Source: Herz)
Source: Herz - November 29, 2020 Category: Cardiology Tags: Herz Source Type: research

Echocardiographic assessment in cardiogenic shock.
Authors: Okutucu S, Fatihoglu SG, Lacoste MO, Oto A Abstract Echocardiography is the most helpful diagnostic modality in cardiogenic shock, the management of which still remains challenging despite advances in therapeutic options. The presence of cardiogenic shock portends high mortality rates. Therefore, rapid recognition, identification of the underlying cause, and evaluation of the severity of hemodynamic dysfunction are vital for correct management. Whether the cause of shock is unknown, suspected, or established, echocardiography is utilized in its diagnosis and management as well as to monitor progress. It is...
Source: Herz - November 27, 2020 Category: Cardiology Tags: Herz Source Type: research

[ESC guidelines  2020: acute coronary syndrome without persistent ST-segment elevation : What is new?]
[ESC guidelines 2020: acute coronary syndrome without persistent ST-segment elevation : What is new?] Herz. 2020 Nov 24;: Authors: Thiele H, Jobs A Abstract The European Society of Cardiology (ESC) guidelines for the management of acute coronary syndrome without persistent ST-segment elevation (NSTE-ACS) published in August 2020, replace the former NSTE-ACS guidelines published in 2015. These updated guidelines have some relevant changes for the clinical practice, which include the diagnostic work-up, risk stratification, antithrombotic therapy, invasive or noninvasive coronary diagnostics and als...
Source: Herz - November 27, 2020 Category: Cardiology Tags: Herz Source Type: research

Clinical significance of glycated hemoglobin in acute coronary syndrome patients from the CCC-ACS project : Findings from a  multicenter retrospective observational study.
Clinical significance of glycated hemoglobin in acute coronary syndrome patients from the CCC-ACS project : Findings from a multicenter retrospective observational study. Herz. 2020 Nov 24;: Authors: Zhao X, Kang Y, Wang X, Yang X, Ai G, Liu Y, Xu P, Zhang J, Gu C, Zhang Y, Hao Y, Zhao D, Han Y, CCC investigators Abstract BACKGROUND: Blood glucose levels are associated with the prognosis of patients with acute coronary syndrome (ACS). Glycated hemoglobin (HbA1c) reflects the average blood glucose level. The purpose of the study was to evaluate HbA1c as a prognostic indicator for ACS. METH...
Source: Herz - November 26, 2020 Category: Cardiology Tags: Herz Source Type: research

Myocardial involvement in coronavirus disease 19.
CONCLUSION: Myocardial injury and impaired myocardial function due to COVID-19 are common; however, no correlation was established between cardiac laboratory or echocardiographic values and mortality. Cardiovascular monitoring upon COVID-19 infection is crucial to determine the burden of cardiac involvement. PMID: 33216154 [PubMed - as supplied by publisher] (Source: Herz)
Source: Herz - November 21, 2020 Category: Cardiology Tags: Herz Source Type: research

[Medication-based secondary prevention in patients with peripheral arterial occlusive disease : An analysis based on secondary data].
Authors: Gebauer K, Wintersohl K, Kraska R, Kortendick K, Fahrland U, Freisinger E, Meyborg M, Stella J, Engelbertz C, Reinecke H, Malyar N Abstract BACKGROUND: Peripheral arterial occlusive disease (PAOD) is an atherosclerotic vascular disease with high morbidity and mortality. A consistent medication-based secondary prevention is part of the essential and evidence-based treatment of PAOD. The aim of this study was to ascertain the status quo of medicinal secondary prevention based on submitted prescriptions. METHODS: In the time period from 2014 to 2017 patients with a confirmed PAOD coding (I70.2-/I73.9-) we...
Source: Herz - November 20, 2020 Category: Cardiology Tags: Herz Source Type: research

Impaired left atrial mechanical functions as indicators for increased aortic root diameter in hypertensive and diabetic patients.
CONCLUSION: Impaired LA mechanical functions determined by speckle tracking methods are related with increased ARD independent of LV diastolic dysfunction. PMID: 33196863 [PubMed - as supplied by publisher] (Source: Herz)
Source: Herz - November 19, 2020 Category: Cardiology Tags: Herz Source Type: research

Value of microalbuminuria in the diagnosis of heart failure with preserved ejection fraction.
Authors: Chen L, Jin C, Chen L, Li M, Zhong Y, Xu Y Abstract OBJECTIVE: Elevated microalbuminuria (MAU) levels have been demonstrated in patients with heart failure with reduced ejection fraction (HFrEF). However, nothing is known about MAU levels in patients with heart failure with preserved ejection fraction (HFpEF). Therefore, the aim of our study was to explore the relationship between MAU levels and HFpEF. METHODS: The MAU and N‑terminal B‑type natriuretic peptide (NT-proBNP) concentrations were examined in 260 participants, including 160 patients with HFpEF and 100 control subjects without HF. Ec...
Source: Herz - October 31, 2020 Category: Cardiology Tags: Herz Source Type: research

Onco-Cardiology: tackling the ugly.
Authors: Rassaf T, Bauersachs J PMID: 33094364 [PubMed - in process] (Source: Herz)
Source: Herz - October 24, 2020 Category: Cardiology Tags: Herz Source Type: research

Genetic association between eNOS gene polymorphisms and risk of carotid atherosclerosis : A  meta-analysis.
CONCLUSION: Our study provides evidence that the allelic and recessive models of the eNOS T786C polymorphism and the allelic and dominant models of the eNOS 4a/4b polymorphism may increase the risk of CAS in Asian populations. PMID: 33095272 [PubMed - as supplied by publisher] (Source: Herz)
Source: Herz - October 24, 2020 Category: Cardiology Tags: Herz Source Type: research

Prognostic value of DCTA scoring system in heart failure.
CONCLUSION: D‑dimer, total cholesterol, hs-cTnT, and serum albumin levels were independent prognostic factors in the setting of heart failure. A novel and comprehensive scoring system based on these biomarkers is an easily available and effective tool for predicting the adverse outcomes of patients with heart failure. PMID: 33084909 [PubMed - as supplied by publisher] (Source: Herz)
Source: Herz - October 22, 2020 Category: Cardiology Tags: Herz Source Type: research

[Echocardiographic examinations in times of the COVID-19 pandemic : International recommendations and implementation].
This article summarizes the current recommendations of international societies and describes the local implementation in Austria. PMID: 33064159 [PubMed - as supplied by publisher] (Source: Herz)
Source: Herz - October 20, 2020 Category: Cardiology Tags: Herz Source Type: research

[Heart failure protection by SGLT2 inhibitors in patients with type  2 diabetes mellitus: evidence and possible mechanisms : A systematic review].
CONCLUSION: The SGLT2 inhibitors show a moderate heart failure protective effect in diabetic patients. It is likely that a nephroprotective effect with modulation of the cardiorenal interaction is an important part of the mechanism of action but this must be substantiated in further investigations. PMID: 33044563 [PubMed - as supplied by publisher] (Source: Herz)
Source: Herz - October 14, 2020 Category: Cardiology Tags: Herz Source Type: research

[Aortic stenosis-which diagnostic algorithms and which treatment?]
Authors: Erbel R Abstract The progress in cardiology during the last 50 years can best be studied by looking at the diagnostics and treatment of patients with aortic valve stenosis. Previously, the clinical examination, electrocardiography (ECG) and chest X‑ray were used before heart catheterization, which included a transseptal puncture to complete the indications for surgery in young patients. Nowadays, echocardiography, often combined with a dobutamine stress test, is the primary diagnostic tool to which computed tomography for quantification of valve calcification and cardiac magnetic resonance...
Source: Herz - October 10, 2020 Category: Cardiology Tags: Herz Source Type: research

Effects of SARS-CoV-2 and its functional receptor ACE2 on the cardiovascular system.
Authors: Li M, Chen S, Xiang X, Wang Q, Liu X Abstract The clinical manifestations of COVID-19 are mainly respiratory symptoms, but some patients present with cardiovascular system disease such as palpitations and shortness of breath as the first or secondary symptoms. In this paper, we describe the characteristics of SARS-CoV‑2 and its functional receptor angiotensin-converting enzyme 2 (ACE2). Furthermore, we explore the impact of virus-induced myocardial damage, decreased ACE2 activity, immune imbalance, hypoxemia, and heart damage caused by antiviral drugs. PMID: 33025029 [PubMed - as supplied by pub...
Source: Herz - October 8, 2020 Category: Cardiology Tags: Herz Source Type: research

Outcomes after transcatheter aortic valve replacement in older patients.
Authors: Kara K, Kloppe A, Ewers A, Bösche L, Aweimer A, Erdogan H, Schöne D, Schiedat F, Patsalis N, Haldenwang PL, Strauch JT, Mügge A, Patsalis PC Abstract BACKGROUND: The prevalence of aortic valve stenosis is increasing due to the continuously growing geriatric population. Data on procedural success and mortality of very old patients are sparse, raising the question of when this population may be deemed as "too old even for transcatheter aortic valve replacement (TAVR)." We, therefore, sought to evaluate the influence of age on outcome after TAVR and the impact of direct implantation. ...
Source: Herz - October 8, 2020 Category: Cardiology Tags: Herz Source Type: research

Reduced rate of admissions for acute coronary syndromes during the COVID-19 pandemic: an observational analysis from a  tertiary hospital in Germany.
Reduced rate of admissions for acute coronary syndromes during the COVID-19 pandemic: an observational analysis from a tertiary hospital in Germany. Herz. 2020 Oct 07;: Authors: Vacanti G, Bramlage P, Schymik G, Schmitt C, Luik A, Swojanowsky P, Tzamalis P Abstract BACKGROUND: Several observational studies have suggested a worrying reduction in hospitalisations for acute coronary syndromes in the emergency cardiology department in the last few months all over the world. The aim of the present study is to assess the impact of the current COVID-19 health crisis on admission for acute coronary s...
Source: Herz - October 8, 2020 Category: Cardiology Tags: Herz Source Type: research

Influence of ablation index on the incidence of cardiac tamponade complicating pulmonary vein isolation.
Authors: Reinsch N, Füting A, Buchholz J, Ruprecht U, Neven K Abstract BACKGROUND: Cardiac tamponade (CT) complicating pulmonary vein isolation (PVI) for atrial fibrillation (AF) is a complication that can increase morbidity and mortality. Radiofrequency energy is a known cause of CT. Ablation Index (AI) is a novel ablation quality marker. We hypothesized that use of AI reduces the incidence of CT. METHODS: All AF procedures between 10/2014 and 06/2019 were included. Three ablation groups were defined: group A, RF ablation with non-contact force (CF) catheter; group B, RF ablation ...
Source: Herz - October 8, 2020 Category: Cardiology Tags: Herz Source Type: research

[Hair cortisol as chronic stress parameter in patients with acute ST-segment elevation myocardial infarction].
CONCLUSION: The results of this study showed that patients with acute ST-segment elevation myocardial infarction did not have significantly higher levels of hair cortisol compared to the reference group; however, long-term metabolic changes as well as advanced chronic heart failure appear to be long-acting stress factors for the organism and increase cortisol levels in hair. PMID: 33026485 [PubMed - as supplied by publisher] (Source: Herz)
Source: Herz - October 8, 2020 Category: Cardiology Tags: Herz Source Type: research

Transvenous extraction of pacemaker leads via femoral approach using a  gooseneck snare.
Transvenous extraction of pacemaker leads via femoral approach using a gooseneck snare. Herz. 2020 Oct 02;: Authors: Uslu A, Küp A, Kanar BG, Balaban I, Demir S, Gülşen K, Kepez A, Doğan C, Candan Ö, Akgün T, Altıntas B, Sadıc BO Abstract BACKGROUND: The growing problem of endocardial lead infections and lead malfunctions has increased interest in percutaneous lead-removal technology. Transvenous lead extraction (TLE) via simple manual traction (SMT) is the first-line therapy. When SMT is not successful, TLE from the femoral vein using a gooseneck snare (GS) with a&nbs...
Source: Herz - October 5, 2020 Category: Cardiology Tags: Herz Source Type: research

Heart failure with preserved ejection fraction, atrial fibrillation, and increased NT ‑proBNP levels : An emergent clinical dilemma.
CONCLUSION: Patients with HFpEF and AF have higher levels of NT-proBNP, which may exceed the upper limits defined in guidelines. This study underlines the importance of measuring NT-proBNP levels in the stable phase and proposes a rule-in level for the decompensated phase. PMID: 32997152 [PubMed - as supplied by publisher] (Source: Herz)
Source: Herz - October 2, 2020 Category: Cardiology Tags: Herz Source Type: research

Pulmonary hypertension due to left heart disease with pulmonary arterial wedge pressure ≤15 mm Hg.
CONCLUSION: We found that 15.6% of the patients with PH-LHD under pharmacological or nonpharmacological treatment had PAWP ≤15 mm Hg. These results suggest that the diagnostic criterion of PAWP and the characteristics for this group of patients should be further investigated. PMID: 32990814 [PubMed - as supplied by publisher] (Source: Herz)
Source: Herz - October 1, 2020 Category: Cardiology Tags: Herz Source Type: research

[Comparison between chest pain units and stroke units : Essential components of the vascular emergency care system: comparison of structure, certification process, quality benchmarking and reimbursement].
CONCLUSION: The well-established CPU concept could additionally benefit from a superordinate quality control. Adequate quality benchmarking appears to be fundamental for gap analyses and for the establishment of a separate remuneration structure. In this respect the German Society for Cardiology as the certifying institution is required to establish an appropriate mechanism within the framework of regular updates of criteria. PMID: 32990815 [PubMed - as supplied by publisher] (Source: Herz)
Source: Herz - October 1, 2020 Category: Cardiology Tags: Herz Source Type: research

Current evidence of survival benefit between chest-compression only versus standard cardiopulmonary resuscitation in out-of-hospital cardiac arrest : Updated systematic review and meta-analysis of randomized controlled trials with trial sequential analysis.
CONCLUSION: Based on these analyses, evidence is inadequate to conclude the superiority of one CPR method over the other. Further trials with larger numbers of patients are needed to deem a conclusive and stable meta-analysis. PMID: 32975628 [PubMed - as supplied by publisher] (Source: Herz)
Source: Herz - September 26, 2020 Category: Cardiology Tags: Herz Source Type: research

Evaluation of thrombolytic treatment effect on frontal plane QRS-T angle in patients with acute pulmonary embolism : A  novel marker of successful thrombolysis.
CONCLUSION: Right ventricular pressure overload in APE has an effect on f(QRS-T). In thrombolytic treatment, the change of f(QRS-T) angle may be a marker of successful thrombolysis. PMID: 32975629 [PubMed - as supplied by publisher] (Source: Herz)
Source: Herz - September 26, 2020 Category: Cardiology Tags: Herz Source Type: research