Aortic and valvular heart diseases, cardiomyopathies and heart failure in pregnancy : Risk assessment and management
Herz. 2021 Jul 14. doi: 10.1007/s00059-021-05049-8. Online ahead of print.ABSTRACTWomen with known cardiovascular diseases (CVD) and a desire to have children should receive a timely comprehensive counselling before becoming pregnant. This is critical as the foundation for an informed decision-making process of the mother and her family. Furthermore, a detailed interdisciplinary management plan should be developed and discussed with the patient. The modified World Health Organization (mWHO) classification should be applied for maternal cardiovascular risk stratification. Although the prevalence of aortic pathologies is inf...
Source: Herz - July 14, 2021 Category: Cardiology Authors: Vera Regitz-Zagrosek Janina Kr üger Karen Sliwa Source Type: research

Anticoagulation in special patient populations with atrial fibrillation
Herz. 2021 Jul 5. doi: 10.1007/s00059-021-05042-1. Online ahead of print.ABSTRACTAnticoagulation in patients with atrial fibrillation (AF) should be guided by considerations of the risk of thromboembolism, stroke, and bleeding as well as the patient's preference. Well-recognized scores have been developed to help the clinician in daily risk assessment, but there are several special patient populations for whom scores are not developed or validated. Furthermore, these patients were not adequately represented in the pivotal randomized trials for non-vitamin K antagonist oral anticoagulants (NOACs). In patients with cancer, t...
Source: Herz - July 5, 2021 Category: Cardiology Authors: Laura Ueberham Gerhard Hindricks Source Type: research

Atrial remodeling and atrial fibrillation recurrence after catheter ablation : Past, present, and future developments
Herz. 2021 Jul 5. doi: 10.1007/s00059-021-05050-1. Online ahead of print.ABSTRACTThe term "atrial remodeling" is used to describe the electrical, mechanical, and structural changes associated with the presence of an arrhythmogenic substrate for atrial fibrillation. Rhythm control therapy may slow down or even reverse progressive atrial remodeling. Atrial remodeling has long been recognized as an important predictor of clinical outcomes and therapeutic success, but recent advances have highlighted its clinical relevance and revealed the implications of specific anatomical changes such as atrial asymmetry or shape....
Source: Herz - July 5, 2021 Category: Cardiology Authors: Sotirios Nedios Frank Lindemann Jordi Heijman Harry J G M Crijns Andreas Bollmann Gerhard Hindricks Source Type: research

Anticoagulation in special patient populations with atrial fibrillation
Herz. 2021 Jul 5. doi: 10.1007/s00059-021-05042-1. Online ahead of print.ABSTRACTAnticoagulation in patients with atrial fibrillation (AF) should be guided by considerations of the risk of thromboembolism, stroke, and bleeding as well as the patient's preference. Well-recognized scores have been developed to help the clinician in daily risk assessment, but there are several special patient populations for whom scores are not developed or validated. Furthermore, these patients were not adequately represented in the pivotal randomized trials for non-vitamin K antagonist oral anticoagulants (NOACs). In patients with cancer, t...
Source: Herz - July 5, 2021 Category: Cardiology Authors: Laura Ueberham Gerhard Hindricks Source Type: research

Atrial remodeling and atrial fibrillation recurrence after catheter ablation : Past, present, and future developments
Herz. 2021 Jul 5. doi: 10.1007/s00059-021-05050-1. Online ahead of print.ABSTRACTThe term "atrial remodeling" is used to describe the electrical, mechanical, and structural changes associated with the presence of an arrhythmogenic substrate for atrial fibrillation. Rhythm control therapy may slow down or even reverse progressive atrial remodeling. Atrial remodeling has long been recognized as an important predictor of clinical outcomes and therapeutic success, but recent advances have highlighted its clinical relevance and revealed the implications of specific anatomical changes such as atrial asymmetry or shape....
Source: Herz - July 5, 2021 Category: Cardiology Authors: Sotirios Nedios Frank Lindemann Jordi Heijman Harry J G M Crijns Andreas Bollmann Gerhard Hindricks Source Type: research

Anticoagulation in special patient populations with atrial fibrillation
Herz. 2021 Jul 5. doi: 10.1007/s00059-021-05042-1. Online ahead of print.ABSTRACTAnticoagulation in patients with atrial fibrillation (AF) should be guided by considerations of the risk of thromboembolism, stroke, and bleeding as well as the patient's preference. Well-recognized scores have been developed to help the clinician in daily risk assessment, but there are several special patient populations for whom scores are not developed or validated. Furthermore, these patients were not adequately represented in the pivotal randomized trials for non-vitamin K antagonist oral anticoagulants (NOACs). In patients with cancer, t...
Source: Herz - July 5, 2021 Category: Cardiology Authors: Laura Ueberham Gerhard Hindricks Source Type: research

Atrial remodeling and atrial fibrillation recurrence after catheter ablation : Past, present, and future developments
Herz. 2021 Jul 5. doi: 10.1007/s00059-021-05050-1. Online ahead of print.ABSTRACTThe term "atrial remodeling" is used to describe the electrical, mechanical, and structural changes associated with the presence of an arrhythmogenic substrate for atrial fibrillation. Rhythm control therapy may slow down or even reverse progressive atrial remodeling. Atrial remodeling has long been recognized as an important predictor of clinical outcomes and therapeutic success, but recent advances have highlighted its clinical relevance and revealed the implications of specific anatomical changes such as atrial asymmetry or shape....
Source: Herz - July 5, 2021 Category: Cardiology Authors: Sotirios Nedios Frank Lindemann Jordi Heijman Harry J G M Crijns Andreas Bollmann Gerhard Hindricks Source Type: research

Anticoagulation in special patient populations with atrial fibrillation
Herz. 2021 Jul 5. doi: 10.1007/s00059-021-05042-1. Online ahead of print.ABSTRACTAnticoagulation in patients with atrial fibrillation (AF) should be guided by considerations of the risk of thromboembolism, stroke, and bleeding as well as the patient's preference. Well-recognized scores have been developed to help the clinician in daily risk assessment, but there are several special patient populations for whom scores are not developed or validated. Furthermore, these patients were not adequately represented in the pivotal randomized trials for non-vitamin K antagonist oral anticoagulants (NOACs). In patients with cancer, t...
Source: Herz - July 5, 2021 Category: Cardiology Authors: Laura Ueberham Gerhard Hindricks Source Type: research

Atrial remodeling and atrial fibrillation recurrence after catheter ablation : Past, present, and future developments
Herz. 2021 Jul 5. doi: 10.1007/s00059-021-05050-1. Online ahead of print.ABSTRACTThe term "atrial remodeling" is used to describe the electrical, mechanical, and structural changes associated with the presence of an arrhythmogenic substrate for atrial fibrillation. Rhythm control therapy may slow down or even reverse progressive atrial remodeling. Atrial remodeling has long been recognized as an important predictor of clinical outcomes and therapeutic success, but recent advances have highlighted its clinical relevance and revealed the implications of specific anatomical changes such as atrial asymmetry or shape....
Source: Herz - July 5, 2021 Category: Cardiology Authors: Sotirios Nedios Frank Lindemann Jordi Heijman Harry J G M Crijns Andreas Bollmann Gerhard Hindricks Source Type: research

Anticoagulation in special patient populations with atrial fibrillation
Herz. 2021 Jul 5. doi: 10.1007/s00059-021-05042-1. Online ahead of print.ABSTRACTAnticoagulation in patients with atrial fibrillation (AF) should be guided by considerations of the risk of thromboembolism, stroke, and bleeding as well as the patient's preference. Well-recognized scores have been developed to help the clinician in daily risk assessment, but there are several special patient populations for whom scores are not developed or validated. Furthermore, these patients were not adequately represented in the pivotal randomized trials for non-vitamin K antagonist oral anticoagulants (NOACs). In patients with cancer, t...
Source: Herz - July 5, 2021 Category: Cardiology Authors: Laura Ueberham Gerhard Hindricks Source Type: research

Atrial remodeling and atrial fibrillation recurrence after catheter ablation : Past, present, and future developments
Herz. 2021 Jul 5. doi: 10.1007/s00059-021-05050-1. Online ahead of print.ABSTRACTThe term "atrial remodeling" is used to describe the electrical, mechanical, and structural changes associated with the presence of an arrhythmogenic substrate for atrial fibrillation. Rhythm control therapy may slow down or even reverse progressive atrial remodeling. Atrial remodeling has long been recognized as an important predictor of clinical outcomes and therapeutic success, but recent advances have highlighted its clinical relevance and revealed the implications of specific anatomical changes such as atrial asymmetry or shape....
Source: Herz - July 5, 2021 Category: Cardiology Authors: Sotirios Nedios Frank Lindemann Jordi Heijman Harry J G M Crijns Andreas Bollmann Gerhard Hindricks Source Type: research

Anticoagulation in special patient populations with atrial fibrillation
Herz. 2021 Jul 5. doi: 10.1007/s00059-021-05042-1. Online ahead of print.ABSTRACTAnticoagulation in patients with atrial fibrillation (AF) should be guided by considerations of the risk of thromboembolism, stroke, and bleeding as well as the patient's preference. Well-recognized scores have been developed to help the clinician in daily risk assessment, but there are several special patient populations for whom scores are not developed or validated. Furthermore, these patients were not adequately represented in the pivotal randomized trials for non-vitamin K antagonist oral anticoagulants (NOACs). In patients with cancer, t...
Source: Herz - July 5, 2021 Category: Cardiology Authors: Laura Ueberham Gerhard Hindricks Source Type: research

Atrial remodeling and atrial fibrillation recurrence after catheter ablation : Past, present, and future developments
Herz. 2021 Jul 5. doi: 10.1007/s00059-021-05050-1. Online ahead of print.ABSTRACTThe term "atrial remodeling" is used to describe the electrical, mechanical, and structural changes associated with the presence of an arrhythmogenic substrate for atrial fibrillation. Rhythm control therapy may slow down or even reverse progressive atrial remodeling. Atrial remodeling has long been recognized as an important predictor of clinical outcomes and therapeutic success, but recent advances have highlighted its clinical relevance and revealed the implications of specific anatomical changes such as atrial asymmetry or shape....
Source: Herz - July 5, 2021 Category: Cardiology Authors: Sotirios Nedios Frank Lindemann Jordi Heijman Harry J G M Crijns Andreas Bollmann Gerhard Hindricks Source Type: research

Anticoagulation in special patient populations with atrial fibrillation
Herz. 2021 Jul 5. doi: 10.1007/s00059-021-05042-1. Online ahead of print.ABSTRACTAnticoagulation in patients with atrial fibrillation (AF) should be guided by considerations of the risk of thromboembolism, stroke, and bleeding as well as the patient's preference. Well-recognized scores have been developed to help the clinician in daily risk assessment, but there are several special patient populations for whom scores are not developed or validated. Furthermore, these patients were not adequately represented in the pivotal randomized trials for non-vitamin K antagonist oral anticoagulants (NOACs). In patients with cancer, t...
Source: Herz - July 5, 2021 Category: Cardiology Authors: Laura Ueberham Gerhard Hindricks Source Type: research

Atrial remodeling and atrial fibrillation recurrence after catheter ablation : Past, present, and future developments
Herz. 2021 Jul 5. doi: 10.1007/s00059-021-05050-1. Online ahead of print.ABSTRACTThe term "atrial remodeling" is used to describe the electrical, mechanical, and structural changes associated with the presence of an arrhythmogenic substrate for atrial fibrillation. Rhythm control therapy may slow down or even reverse progressive atrial remodeling. Atrial remodeling has long been recognized as an important predictor of clinical outcomes and therapeutic success, but recent advances have highlighted its clinical relevance and revealed the implications of specific anatomical changes such as atrial asymmetry or shape....
Source: Herz - July 5, 2021 Category: Cardiology Authors: Sotirios Nedios Frank Lindemann Jordi Heijman Harry J G M Crijns Andreas Bollmann Gerhard Hindricks Source Type: research

Clinical review of sick sinus syndrome and atrial fibrillation
Herz. 2021 Jun 22. doi: 10.1007/s00059-021-05046-x. Online ahead of print.ABSTRACTSick sinus syndrome (SSS) is a set of diseases with abnormal cardiac pacing, which manifests as diverse cardiac arrhythmias, especially bradycardia. The clinical presentation is inconspicuous in the early stage, but with the progression of this disease, patients may present with symptoms and signs of end-organ hypoperfusion. As a common result in the natural history of the disease, SSS coexisting with atrial fibrillation (AF) forms the basis of bradycardia-tachycardia syndrome. Age-related interstitial fibrosis is considered to be the common ...
Source: Herz - June 22, 2021 Category: Cardiology Authors: Wenxing Chang Guangsen Li Source Type: research

Pulmonary vein isolation in atrial fibrillation using pulsed field ablation
Herz. 2021 Jun 17. doi: 10.1007/s00059-021-05047-w. Online ahead of print.ABSTRACTAtrial fibrillation is the most common supraventricular arrhythmia with increasing incidence and prevalence. Until now, thermal energy sources such as radiofrequency or cryoablation have been used for pulmonary vein isolation of atrial fibrillation but these have led to indiscriminate tissue destruction in the target area. Pulsed field ablation (PFA) is an energy modality that does not utilize thermal effects. An ultrarapid electric field produces irreversible changes in cell membrane pores (irreversible electroporation) culminating in cell d...
Source: Herz - June 18, 2021 Category: Cardiology Authors: F Lindemann S Nedios T Seew öster G Hindricks Source Type: research

Effects of oral colchicine administration as first-line  adjunct therapy in myopericarditis
Herz. 2021 Jun 10. doi: 10.1007/s00059-021-05040-3. Online ahead of print.ABSTRACTBACKGROUND: Although current guidelines recommend routine use of oral colchicine as a first-line adjunct therapy to aspirin/nonsteroidal anti-inflammatory drugs (NSAIDs) for acute and recurrent pericarditis, there are insufficient data to recommend routine use of colchicine for the initial management of myopericarditis.METHODS: The records of 194 patients who were admitted for myopericarditis were investigated retrospectively. Patients receiving oral colchicine (n = 33) as an adjunct to aspirin/NSAIDs comprised the study group and patients wh...
Source: Herz - June 11, 2021 Category: Cardiology Authors: Mustafa Duran Yakup Alsancak Murat Ziyrek Source Type: research

Acute effects of inhaled iloprost on intracardiac conduction in patients with pulmonary arterial hypertension
CONCLUSION: Inhaled iloprost can improve cardiovascular performance in the presence of PAH, primarily through a reduction in right ventricular afterload and interventricular pressure. Decreased pressure on the interventricular septum and ventricles leads to conduction system normalization including of the AH interval and SNRT due to resolution of inflammation and edema.PMID:34114047 | DOI:10.1007/s00059-021-05044-z (Source: Herz)
Source: Herz - June 11, 2021 Category: Cardiology Authors: Mustafa Yildiz Serkan Kahraman Ozgur Surgit Hicaz Zencirkiran Agus Begum Uygur Ali R Demir Mehmet E Kalkan Kadriye Memic Sancar Ender Oner İsmail Gurbak Ali K Kalkan Source Type: research

Effects of oral colchicine administration as first-line  adjunct therapy in myopericarditis
Herz. 2021 Jun 10. doi: 10.1007/s00059-021-05040-3. Online ahead of print.ABSTRACTBACKGROUND: Although current guidelines recommend routine use of oral colchicine as a first-line adjunct therapy to aspirin/nonsteroidal anti-inflammatory drugs (NSAIDs) for acute and recurrent pericarditis, there are insufficient data to recommend routine use of colchicine for the initial management of myopericarditis.METHODS: The records of 194 patients who were admitted for myopericarditis were investigated retrospectively. Patients receiving oral colchicine (n = 33) as an adjunct to aspirin/NSAIDs comprised the study group and patients wh...
Source: Herz - June 11, 2021 Category: Cardiology Authors: Mustafa Duran Yakup Alsancak Murat Ziyrek Source Type: research

Acute effects of inhaled iloprost on intracardiac conduction in patients with pulmonary arterial hypertension
CONCLUSION: Inhaled iloprost can improve cardiovascular performance in the presence of PAH, primarily through a reduction in right ventricular afterload and interventricular pressure. Decreased pressure on the interventricular septum and ventricles leads to conduction system normalization including of the AH interval and SNRT due to resolution of inflammation and edema.PMID:34114047 | DOI:10.1007/s00059-021-05044-z (Source: Herz)
Source: Herz - June 11, 2021 Category: Cardiology Authors: Mustafa Yildiz Serkan Kahraman Ozgur Surgit Hicaz Zencirkiran Agus Begum Uygur Ali R Demir Mehmet E Kalkan Kadriye Memic Sancar Ender Oner İsmail Gurbak Ali K Kalkan Source Type: research

Effects of oral colchicine administration as first-line  adjunct therapy in myopericarditis
Herz. 2021 Jun 10. doi: 10.1007/s00059-021-05040-3. Online ahead of print.ABSTRACTBACKGROUND: Although current guidelines recommend routine use of oral colchicine as a first-line adjunct therapy to aspirin/nonsteroidal anti-inflammatory drugs (NSAIDs) for acute and recurrent pericarditis, there are insufficient data to recommend routine use of colchicine for the initial management of myopericarditis.METHODS: The records of 194 patients who were admitted for myopericarditis were investigated retrospectively. Patients receiving oral colchicine (n = 33) as an adjunct to aspirin/NSAIDs comprised the study group and patients wh...
Source: Herz - June 11, 2021 Category: Cardiology Authors: Mustafa Duran Yakup Alsancak Murat Ziyrek Source Type: research

Acute effects of inhaled iloprost on intracardiac conduction in patients with pulmonary arterial hypertension
CONCLUSION: Inhaled iloprost can improve cardiovascular performance in the presence of PAH, primarily through a reduction in right ventricular afterload and interventricular pressure. Decreased pressure on the interventricular septum and ventricles leads to conduction system normalization including of the AH interval and SNRT due to resolution of inflammation and edema.PMID:34114047 | DOI:10.1007/s00059-021-05044-z (Source: Herz)
Source: Herz - June 11, 2021 Category: Cardiology Authors: Mustafa Yildiz Serkan Kahraman Ozgur Surgit Hicaz Zencirkiran Agus Begum Uygur Ali R Demir Mehmet E Kalkan Kadriye Memic Sancar Ender Oner İsmail Gurbak Ali K Kalkan Source Type: research

Effects of oral colchicine administration as first-line  adjunct therapy in myopericarditis
Herz. 2021 Jun 10. doi: 10.1007/s00059-021-05040-3. Online ahead of print.ABSTRACTBACKGROUND: Although current guidelines recommend routine use of oral colchicine as a first-line adjunct therapy to aspirin/nonsteroidal anti-inflammatory drugs (NSAIDs) for acute and recurrent pericarditis, there are insufficient data to recommend routine use of colchicine for the initial management of myopericarditis.METHODS: The records of 194 patients who were admitted for myopericarditis were investigated retrospectively. Patients receiving oral colchicine (n = 33) as an adjunct to aspirin/NSAIDs comprised the study group and patients wh...
Source: Herz - June 11, 2021 Category: Cardiology Authors: Mustafa Duran Yakup Alsancak Murat Ziyrek Source Type: research

Acute effects of inhaled iloprost on intracardiac conduction in patients with pulmonary arterial hypertension
CONCLUSION: Inhaled iloprost can improve cardiovascular performance in the presence of PAH, primarily through a reduction in right ventricular afterload and interventricular pressure. Decreased pressure on the interventricular septum and ventricles leads to conduction system normalization including of the AH interval and SNRT due to resolution of inflammation and edema.PMID:34114047 | DOI:10.1007/s00059-021-05044-z (Source: Herz)
Source: Herz - June 11, 2021 Category: Cardiology Authors: Mustafa Yildiz Serkan Kahraman Ozgur Surgit Hicaz Zencirkiran Agus Begum Uygur Ali R Demir Mehmet E Kalkan Kadriye Memic Sancar Ender Oner İsmail Gurbak Ali K Kalkan Source Type: research

Effects of oral colchicine administration as first-line  adjunct therapy in myopericarditis
Herz. 2021 Jun 10. doi: 10.1007/s00059-021-05040-3. Online ahead of print.ABSTRACTBACKGROUND: Although current guidelines recommend routine use of oral colchicine as a first-line adjunct therapy to aspirin/nonsteroidal anti-inflammatory drugs (NSAIDs) for acute and recurrent pericarditis, there are insufficient data to recommend routine use of colchicine for the initial management of myopericarditis.METHODS: The records of 194 patients who were admitted for myopericarditis were investigated retrospectively. Patients receiving oral colchicine (n = 33) as an adjunct to aspirin/NSAIDs comprised the study group and patients wh...
Source: Herz - June 11, 2021 Category: Cardiology Authors: Mustafa Duran Yakup Alsancak Murat Ziyrek Source Type: research

Acute effects of inhaled iloprost on intracardiac conduction in patients with pulmonary arterial hypertension
CONCLUSION: Inhaled iloprost can improve cardiovascular performance in the presence of PAH, primarily through a reduction in right ventricular afterload and interventricular pressure. Decreased pressure on the interventricular septum and ventricles leads to conduction system normalization including of the AH interval and SNRT due to resolution of inflammation and edema.PMID:34114047 | DOI:10.1007/s00059-021-05044-z (Source: Herz)
Source: Herz - June 11, 2021 Category: Cardiology Authors: Mustafa Yildiz Serkan Kahraman Ozgur Surgit Hicaz Zencirkiran Agus Begum Uygur Ali R Demir Mehmet E Kalkan Kadriye Memic Sancar Ender Oner İsmail Gurbak Ali K Kalkan Source Type: research

Effects of oral colchicine administration as first-line  adjunct therapy in myopericarditis
Herz. 2021 Jun 10. doi: 10.1007/s00059-021-05040-3. Online ahead of print.ABSTRACTBACKGROUND: Although current guidelines recommend routine use of oral colchicine as a first-line adjunct therapy to aspirin/nonsteroidal anti-inflammatory drugs (NSAIDs) for acute and recurrent pericarditis, there are insufficient data to recommend routine use of colchicine for the initial management of myopericarditis.METHODS: The records of 194 patients who were admitted for myopericarditis were investigated retrospectively. Patients receiving oral colchicine (n = 33) as an adjunct to aspirin/NSAIDs comprised the study group and patients wh...
Source: Herz - June 11, 2021 Category: Cardiology Authors: Mustafa Duran Yakup Alsancak Murat Ziyrek Source Type: research

Acute effects of inhaled iloprost on intracardiac conduction in patients with pulmonary arterial hypertension
CONCLUSION: Inhaled iloprost can improve cardiovascular performance in the presence of PAH, primarily through a reduction in right ventricular afterload and interventricular pressure. Decreased pressure on the interventricular septum and ventricles leads to conduction system normalization including of the AH interval and SNRT due to resolution of inflammation and edema.PMID:34114047 | DOI:10.1007/s00059-021-05044-z (Source: Herz)
Source: Herz - June 11, 2021 Category: Cardiology Authors: Mustafa Yildiz Serkan Kahraman Ozgur Surgit Hicaz Zencirkiran Agus Begum Uygur Ali R Demir Mehmet E Kalkan Kadriye Memic Sancar Ender Oner İsmail Gurbak Ali K Kalkan Source Type: research

Cardiovascular disease in patients with chronic kidney disease
Herz. 2021 Jun;46(3):205. doi: 10.1007/s00059-021-05029-y. Epub 2021 Jun 10.NO ABSTRACTPMID:34110441 | DOI:10.1007/s00059-021-05029-y (Source: Herz)
Source: Herz - June 10, 2021 Category: Cardiology Authors: Nikolaus Marx J ürgen Floege Source Type: research

Mapping atrial fibrillation : An overview of potential mechanisms underlying atrial fibrillation
This article focuses on milestones in the theory of atrial fibrillation and addresses the different leading hypotheses concerning atrial fibrillation mechanisms. We start off with electric potential originating from the pulmonary vein, which triggers atrial fibrillation, discuss classic activation mapping and phase mapping as well as computer models, which have contributed to the our understanding of atrial fibrillation, and end with new mapping methods and studies highlighting the advantages and disadvantages of current mechanistic hypotheses. The technical evolution of mapping atrial fibrillation has led to new insights ...
Source: Herz - June 9, 2021 Category: Cardiology Authors: Christopher Kowalewski Source Type: research