Interfaces in cardiovascular medicine
Herz. 2024 Mar;49(2):91-94. doi: 10.1007/s00059-024-05238-1. Epub 2024 Mar 6.NO ABSTRACTPMID:38446178 | DOI:10.1007/s00059-024-05238-1 (Source: Herz)
Source: Herz - March 6, 2024 Category: Cardiology Authors: Christoph Maack Source Type: research
Acute prevention of a heart attack : Early identification of prodromal symptoms as the Rosetta Stone in decoding the heart attack problem
Herz. 2024 Mar 6. doi: 10.1007/s00059-024-05239-0. Online ahead of print.ABSTRACTChest discomfort before severe chest pain represents a marker of clinical ischemia and indicates live myocardium in jeopardy and often precedes cardiac arrest or acute myocardial infarction (MI). The intermittent or "stuttering" symptoms that precede MI are referred to as "prodromal symptoms." These symptoms have been shown to correlate with cyclic ST changes and repeated episodes of spontaneous reperfusion and occlusion, occurring during a period of hours or days before the acute ischemia proceeds to death or heart damage. These symptoms of p...
Source: Herz - March 6, 2024 Category: Cardiology Authors: Raymond D Bahr Source Type: research
Interfaces in cardiovascular medicine
Herz. 2024 Mar;49(2):91-94. doi: 10.1007/s00059-024-05238-1. Epub 2024 Mar 6.NO ABSTRACTPMID:38446178 | DOI:10.1007/s00059-024-05238-1 (Source: Herz)
Source: Herz - March 6, 2024 Category: Cardiology Authors: Christoph Maack Source Type: research
New categorization of chest pain: noncardiac is in, atypical is out!
Herz. 2024 Mar 1. doi: 10.1007/s00059-024-05240-7. Online ahead of print.ABSTRACTChest pain poses a diagnostic challenge in the emergency department and requires a thorough clinical assessment. The traditional distinction between "atypical" and "typical" chest pain carries the risk of not addressing nonischemic clinical pictures. The newly conceived subdivision into cardiac, possibly cardiac, and (probably) noncardiac causes of the presenting symptom complex addresses a much more interdisciplinary approach to a symptom-oriented diagnostic algorithm. The diagnostic structures of the chest pain units in Germany do not curren...
Source: Herz - March 1, 2024 Category: Cardiology Authors: Stephan Settelmeier Sebastian Steven Felix Post Ingo Ahrens Evangelos Giannitsis Frank Breuckmann Arbeitsgruppe Akuter Thoraxschmerz (AG 44) der Deutschen Gesellschaft f ür Kardiologie – Herz- und Kreislaufforschung e. V. (DGK) Source Type: research
Heart and blood: clonal hematopoiesis
Herz. 2024 Feb 29. doi: 10.1007/s00059-024-05237-2. Online ahead of print.ABSTRACTCardiovascular diseases are among the leading causes of death worldwide, with well-known modifiable risk factors, such as smoking, overweight, lipid metabolism disorders, lack of physical activity and high blood pressure playing a significant role. Recent studies have now identified "clonal hematopoiesis" as a novel blood-based risk factor. Clonal hematopoiesis arises from mutations in hematopoietic stem cells, which lead to the expansion of mutated blood cells. Mutated cell clones can be detected in over 40% of individuals over 50 years old,...
Source: Herz - February 29, 2024 Category: Cardiology Authors: Stefanie Dimmeler Andreas Zeiher Source Type: research
Increased cardiovascular risk in patients with chronic kidney disease
Herz. 2024 Feb 28. doi: 10.1007/s00059-024-05235-4. Online ahead of print.ABSTRACTCardiovascular disease (CVD) is highly prevalent in patients suffering from chronic kidney disease (CKD). The risk of patients with CKD developing CVD is manifested already in the early stages of CKD development. The impact of declined kidney function on increased cardiovascular risk and the underlying mechanisms are complex and multifactorial. This review discusses the impact of (a) traditional cardiovascular risk factors such as smoking, dyslipidemia, diabetes, and hypertension as well as (b) CKD-specific pathophysiological and molecular me...
Source: Herz - February 28, 2024 Category: Cardiology Authors: Sonja Vondenhoff Stefan J Schunk Heidi Noels Source Type: research
Erratum zu: ESC-Leitlinien 2023 zum Management der Endokarditis
Herz. 2024 Feb 28. doi: 10.1007/s00059-024-05236-3. Online ahead of print.NO ABSTRACTPMID:38418606 | DOI:10.1007/s00059-024-05236-3 (Source: Herz)
Source: Herz - February 28, 2024 Category: Cardiology Authors: Suzanne de Waha Steffen Desch Roland Tilz Julia Vogler Madlen Uhlemann Mateo Mar ín-Cuartas Matthias Raschpichler Michael Borger Source Type: research
Increased cardiovascular risk in patients with chronic kidney disease
Herz. 2024 Feb 28. doi: 10.1007/s00059-024-05235-4. Online ahead of print.ABSTRACTCardiovascular disease (CVD) is highly prevalent in patients suffering from chronic kidney disease (CKD). The risk of patients with CKD developing CVD is manifested already in the early stages of CKD development. The impact of declined kidney function on increased cardiovascular risk and the underlying mechanisms are complex and multifactorial. This review discusses the impact of (a) traditional cardiovascular risk factors such as smoking, dyslipidemia, diabetes, and hypertension as well as (b) CKD-specific pathophysiological and molecular me...
Source: Herz - February 28, 2024 Category: Cardiology Authors: Sonja Vondenhoff Stefan J Schunk Heidi Noels Source Type: research
Erratum zu: ESC-Leitlinien 2023 zum Management der Endokarditis
Herz. 2024 Feb 28. doi: 10.1007/s00059-024-05236-3. Online ahead of print.NO ABSTRACTPMID:38418606 | DOI:10.1007/s00059-024-05236-3 (Source: Herz)
Source: Herz - February 28, 2024 Category: Cardiology Authors: Suzanne de Waha Steffen Desch Roland Tilz Julia Vogler Madlen Uhlemann Mateo Mar ín-Cuartas Matthias Raschpichler Michael Borger Source Type: research
Cardiac proteostasis in obesity and cardiovascular disease
Herz. 2024 Feb 8. doi: 10.1007/s00059-024-05233-6. Online ahead of print.ABSTRACTCardiovascular diseases (CVD) are closely linked to protein homeostasis (proteostasis) and its failure. Beside genetic mutations that impair cardiac protein quality control, obesity is a strong risk factor for heart disease. In obesity, adipose tissue becomes dysfunctional and impacts heart function and CVD progression by releasing cytokines that contribute to systemic insulin resistance and cardiovascular dysfunction. In addition, chronic inflammation and lipotoxicity compromise endoplasmic reticulum (ER) function, eliciting stress responses ...
Source: Herz - February 8, 2024 Category: Cardiology Authors: Joel Guerra Leonardo Matta Alexander Bartelt Source Type: research
