Advances in pediatric anesthesia services over the past 10  years in French-speaking sub-Saharan Africa
CONCLUSION: Progress have been made over the last 10 years in French-speaking SSA to improve infrastructures, human resources, education, medications, and equipment for pediatric anesthesia in French-speaking SSA. However, major efforts must be continued. Standards adapted to the local context should be formulated.PMID:38655778 | DOI:10.1111/pan.14904 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - April 24, 2024 Category: Anesthesiology Authors: K élan Bertille Ki Fatou Fleur Sanou Marie Ndoye Diop Ismael Guibla Mamadou Traore Joseph Donamou Moustapha Mangane Yvette Kabre Hadjara Daddy Buhendwa Jean Paul Cikwanine Hamza Sama Joseph Akodjenou Adjougoulta Koboy Do-A-Nduo Bonte Junete Metogo Mbengo Source Type: research

Fentanyl Analogs Exert Antinociceptive Effects via Sodium Channel Blockade in Mice
This study investigated whether opioid-related compounds could suppress glutamate- and veratrine-induced nociceptive responses in mice at the same dose. The administration of morphine (3 mg/kg), hydromorphone (0.4 mg/kg), or fentanyl (0.03 mg/kg) suppressed glutamate-induced nociceptive response, but not veratrine-induced nociceptive response at the same doses. However, high doses of morphine (10 mg/kg), hydromorphone (2 mg/kg), or fentanyl (0.1 mg/kg) produced a significant reduction in the veratrine-induced nociceptive response. These results indicate that high doses are required when using morphine, hydromorphone, or fe...
Source: Biological and Pharmaceutical Bulletin - April 24, 2024 Category: Drugs & Pharmacology Authors: Satoka Kasai Natsuki Ogawa Miho Takagi Yukino Takahashi Kosho Makino Hironobu Arita Hideyo Takahashi Kazumi Yoshizawa Source Type: research

Ultrasound-guided distal glossopharyngeal nerve block for post-tonsillectomy pain relief in adults: a prospective randomized study
CONCLUSIONS: In patients having tonsillectomy, pre-emptive application of US-guided distal GPN block at the pharyngeal wall enhanced the quality of analgesia and decreased the need for rescue analgesics with no major adverse effects.PMID:38656086 | DOI:10.23736/S0375-9393.24.17925-4 (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - April 24, 2024 Category: Anesthesiology Authors: Mohamed S Abdelghany Gehan M Eid Aliaa M Belal Mona B El Mourad Source Type: research

Advances in pediatric anesthesia services over the past 10  years in French-speaking sub-Saharan Africa
CONCLUSION: Progress have been made over the last 10 years in French-speaking SSA to improve infrastructures, human resources, education, medications, and equipment for pediatric anesthesia in French-speaking SSA. However, major efforts must be continued. Standards adapted to the local context should be formulated.PMID:38655778 | DOI:10.1111/pan.14904 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - April 24, 2024 Category: Anesthesiology Authors: K élan Bertille Ki Fatou Fleur Sanou Marie Ndoye Diop Ismael Guibla Mamadou Traore Joseph Donamou Moustapha Mangane Yvette Kabre Hadjara Daddy Buhendwa Jean Paul Cikwanine Hamza Sama Joseph Akodjenou Adjougoulta Koboy Do-A-Nduo Bonte Junete Metogo Mbengo Source Type: research

Fentanyl Analogs Exert Antinociceptive Effects via Sodium Channel Blockade in Mice
This study investigated whether opioid-related compounds could suppress glutamate- and veratrine-induced nociceptive responses in mice at the same dose. The administration of morphine (3 mg/kg), hydromorphone (0.4 mg/kg), or fentanyl (0.03 mg/kg) suppressed glutamate-induced nociceptive response, but not veratrine-induced nociceptive response at the same doses. However, high doses of morphine (10 mg/kg), hydromorphone (2 mg/kg), or fentanyl (0.1 mg/kg) produced a significant reduction in the veratrine-induced nociceptive response. These results indicate that high doses are required when using morphine, hydromorphone, or fe...
Source: Biological and Pharmaceutical Bulletin - April 24, 2024 Category: Drugs & Pharmacology Authors: Satoka Kasai Natsuki Ogawa Miho Takagi Yukino Takahashi Kosho Makino Hironobu Arita Hideyo Takahashi Kazumi Yoshizawa Source Type: research

Ultrasound-guided distal glossopharyngeal nerve block for post-tonsillectomy pain relief in adults: a prospective randomized study
CONCLUSIONS: In patients having tonsillectomy, pre-emptive application of US-guided distal GPN block at the pharyngeal wall enhanced the quality of analgesia and decreased the need for rescue analgesics with no major adverse effects.PMID:38656086 | DOI:10.23736/S0375-9393.24.17925-4 (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - April 24, 2024 Category: Anesthesiology Authors: Mohamed S Abdelghany Gehan M Eid Aliaa M Belal Mona B El Mourad Source Type: research

Fentanyl Analogs Exert Antinociceptive Effects via Sodium Channel Blockade in Mice
This study investigated whether opioid-related compounds could suppress glutamate- and veratrine-induced nociceptive responses in mice at the same dose. The administration of morphine (3 mg/kg), hydromorphone (0.4 mg/kg), or fentanyl (0.03 mg/kg) suppressed glutamate-induced nociceptive response, but not veratrine-induced nociceptive response at the same doses. However, high doses of morphine (10 mg/kg), hydromorphone (2 mg/kg), or fentanyl (0.1 mg/kg) produced a significant reduction in the veratrine-induced nociceptive response. These results indicate that high doses are required when using morphine, hydromorphone, or fe...
Source: Biological and Pharmaceutical Bulletin - April 24, 2024 Category: Drugs & Pharmacology Authors: Satoka Kasai Natsuki Ogawa Miho Takagi Yukino Takahashi Kosho Makino Hironobu Arita Hideyo Takahashi Kazumi Yoshizawa Source Type: research

Ultrasound-guided distal glossopharyngeal nerve block for post-tonsillectomy pain relief in adults: a prospective randomized study
CONCLUSIONS: In patients having tonsillectomy, pre-emptive application of US-guided distal GPN block at the pharyngeal wall enhanced the quality of analgesia and decreased the need for rescue analgesics with no major adverse effects.PMID:38656086 | DOI:10.23736/S0375-9393.24.17925-4 (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - April 24, 2024 Category: Anesthesiology Authors: Mohamed S Abdelghany Gehan M Eid Aliaa M Belal Mona B El Mourad Source Type: research

Fentanyl Analogs Exert Antinociceptive Effects via Sodium Channel Blockade in Mice
This study investigated whether opioid-related compounds could suppress glutamate- and veratrine-induced nociceptive responses in mice at the same dose. The administration of morphine (3 mg/kg), hydromorphone (0.4 mg/kg), or fentanyl (0.03 mg/kg) suppressed glutamate-induced nociceptive response, but not veratrine-induced nociceptive response at the same doses. However, high doses of morphine (10 mg/kg), hydromorphone (2 mg/kg), or fentanyl (0.1 mg/kg) produced a significant reduction in the veratrine-induced nociceptive response. These results indicate that high doses are required when using morphine, hydromorphone, or fe...
Source: Biological and Pharmaceutical Bulletin - April 24, 2024 Category: Drugs & Pharmacology Authors: Satoka Kasai Natsuki Ogawa Miho Takagi Yukino Takahashi Kosho Makino Hironobu Arita Hideyo Takahashi Kazumi Yoshizawa Source Type: research

Ultrasound-guided distal glossopharyngeal nerve block for post-tonsillectomy pain relief in adults: a prospective randomized study
CONCLUSIONS: In patients having tonsillectomy, pre-emptive application of US-guided distal GPN block at the pharyngeal wall enhanced the quality of analgesia and decreased the need for rescue analgesics with no major adverse effects.PMID:38656086 | DOI:10.23736/S0375-9393.24.17925-4 (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - April 24, 2024 Category: Anesthesiology Authors: Mohamed S Abdelghany Gehan M Eid Aliaa M Belal Mona B El Mourad Source Type: research

Fentanyl Analogs Exert Antinociceptive Effects via Sodium Channel Blockade in Mice
This study investigated whether opioid-related compounds could suppress glutamate- and veratrine-induced nociceptive responses in mice at the same dose. The administration of morphine (3 mg/kg), hydromorphone (0.4 mg/kg), or fentanyl (0.03 mg/kg) suppressed glutamate-induced nociceptive response, but not veratrine-induced nociceptive response at the same doses. However, high doses of morphine (10 mg/kg), hydromorphone (2 mg/kg), or fentanyl (0.1 mg/kg) produced a significant reduction in the veratrine-induced nociceptive response. These results indicate that high doses are required when using morphine, hydromorphone, or fe...
Source: Biological and Pharmaceutical Bulletin - April 24, 2024 Category: Drugs & Pharmacology Authors: Satoka Kasai Natsuki Ogawa Miho Takagi Yukino Takahashi Kosho Makino Hironobu Arita Hideyo Takahashi Kazumi Yoshizawa Source Type: research

Ultrasound-guided distal glossopharyngeal nerve block for post-tonsillectomy pain relief in adults: a prospective randomized study
CONCLUSIONS: In patients having tonsillectomy, pre-emptive application of US-guided distal GPN block at the pharyngeal wall enhanced the quality of analgesia and decreased the need for rescue analgesics with no major adverse effects.PMID:38656086 | DOI:10.23736/S0375-9393.24.17925-4 (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - April 24, 2024 Category: Anesthesiology Authors: Mohamed S Abdelghany Gehan M Eid Aliaa M Belal Mona B El Mourad Source Type: research

The 90% effective dose of intrathecal hyperbaric bupivacaine for Cesarean delivery under combined spinal –epidural anesthesia in parturients with super obesity: an up-down sequential allocation study
ConclusionThe estimated ED90 of hyperbaric bupivacaine with fentanyl and morphine in parturients with super obesity undergoing Cesarean delivery under CSE was approximately 11.5 mg.Study registrationClinicalTrials.gov (NCT03781388); first submitted 18 December 2018. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - April 23, 2024 Category: Anesthesiology Source Type: research

Enhanced recovery after surgery improves clinical outcomes in adolescent bariatric surgery
CONCLUSIONS: The described ERAS protocol is safe and effective in adolescents undergoing laparoscopic VSG and is associated with shorter time to oral intake, reduced opioid requirements, and shorter hospital lengths of stay with no increase in return ED visits or readmissions.PMID:38653653 | DOI:10.1016/j.soard.2024.03.016 (Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery)
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - April 23, 2024 Category: Surgery Authors: Nicholas Schmoke Christopher Nemeh Tania Gennell Dana Schapiro Ashley Hiep-Catarino Matthew Alexander Alexander V Chalphin Robert W Crum Leign Holynskyj Tatiana Kubacki William S Schechter Jeffrey Zitsman Source Type: research

Enhanced recovery after surgery improves clinical outcomes in adolescent bariatric surgery
CONCLUSIONS: The described ERAS protocol is safe and effective in adolescents undergoing laparoscopic VSG and is associated with shorter time to oral intake, reduced opioid requirements, and shorter hospital lengths of stay with no increase in return ED visits or readmissions.PMID:38653653 | DOI:10.1016/j.soard.2024.03.016 (Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery)
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - April 23, 2024 Category: Surgery Authors: Nicholas Schmoke Christopher Nemeh Tania Gennell Dana Schapiro Ashley Hiep-Catarino Matthew Alexander Alexander V Chalphin Robert W Crum Leign Holynskyj Tatiana Kubacki William S Schechter Jeffrey Zitsman Source Type: research