A practical approach to the use of targeted temperature management after cardiac arrest.
Authors: Annoni F, Donadello K, Nobile L, Taccone FS Abstract Among comatose survivors after cardiac arrest, target temperature management (TTM) is considered the most effective treatment to reduce the consequences of post-anoxic brain injury. Several international guidelines have thus incorporated TTM in the management of the post- resuscitation phase. However, despite extremely promising results in animal models and in randomized trials including selected patient cohorts, TTM benefits on neurological outcome have been questioned. Moreover, TTM potential side effects have raised some concerns on its wide applicati...
Source: Minerva Anestesiologica - May 30, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Translation and validation of the Italian version of the postoperative quality of recovery score QoR-15.
Authors: Picconi E, Iacobucci T, Adducci E, Gualtieri E, Beccia G, Sollazzi L PMID: 32463210 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 30, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Video call in intensive care and moral distress.
Authors: Borrelli V, Navarra M PMID: 32463211 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 30, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Principled decisions and virtuous care: an ethical assessment of the Siaarti guidelines for allocating intensive care resources.
This article sets forth ethical principles for responding to extraordinary circumstances in which the demand for medical care threatens to overwhelms available resources, as in the COVID-19 pandemic. In light of these principles, the author then assesses the ethics of the SIAARTI guidelines for rationing ICU beds and ventilators under such circumstances. PMID: 32463212 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 30, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Are other effects of Dexmedetomidine playing a role in explaining norepinephrine requirements decrease in septic shock patients?
Authors: Montrucchio G, Sales G, Scanu M, Bosso S, Brazzi L PMID: 32463213 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 30, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Which dynamic measurements for fluid responsiveness? The right ones.
Authors: Bertini P, Guarracino F PMID: 32463214 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 30, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Delayed cerebral ischemia: is it time to change our practice?
Authors: Caricato A, Silva S PMID: 32463215 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 30, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Occurrence of ventilator associated pneumonia using a tracheostomy tube with subglottic secretion drainage.
CONCLUSIONS: Subglottic secretion drainage reduces incidence of VAP in critically ill patients requiring ongoing MV via tracheostomy. PMID: 32449334 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 27, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Could intraoperative magnesium sulphate protect against postoperative cognitive dysfunction?
CONCLUSIONS: Administration of intravenous infusion of magnesium sulphate during conventional general anaesthesia can protect against POCD and attenuate the post operative elevation of serum S100B. PMID: 32449335 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 27, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Comparison between the ultrasound-guided erector spinae block and the subcostal approach to the transversus abdominis plane block in obese patients undergoing sleeve gastrectomy; a randomized controlled trial.
Authors: Abdelhamid BM, Khaled D, Mansour M, Hassan MM Abstract BACKGROUND: Pain control in the morbidly obese has presented as an anesthetic challenge. The aim of this study is to assess the analgesic efficacy of ultrasound guided bilateral erector spinae block compared to bilateral subcostal transversus abdominis plane block. METHODS: Prospective randomized, double-blinded controlled study was conducted at Kasr Alainy Hospital on 66 patients scheduled for laparoscopic sleeve gastrectomy. Patients were randomly allocated into three groups and received general anesthesia: bilateral erector spinae block at the l...
Source: Minerva Anestesiologica - May 27, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Influence of mechanical ventilation and loading modifications on left ventricular global longitudinal strain in patients undergoing general anesthesia. A pilot study.
CONCLUSIONS: Systolic function assessed with GLS is impaired after general anesthesia and invasive mechanical ventilation in patients without cardiovascular co-morbidities but remains within normal range. PMID: 32449337 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 27, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

S100 β as a potential biomarker of incident delirium: a systematic review and meta-analysis.
CONCLUSIONS: This meta-analysis provides evidence that serum S100β seems to be of limited value as a biomarker of delirium, but CSF S100β elevation as a biomarker of delirium, may be more meaningful. PMID: 32449338 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 27, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Dynamic bedside assessment of the physiologic effects of prone position in acute respiratory distress syndrome patients by electrical impedance tomography.
Authors: Dalla Corte F, Mauri T, Spinelli E, Lazzeri M, Turrini C, Albanese M, Abbruzzese C, Lissoni A, Galazzi A, Eronia N, Bronco A, Maffezzini E, Pesenti A, Foti G, Bellani G, Grasselli G Abstract BACKGROUND: Prone position (PP) improves acute respiratory distress syndrome (ARDS) survival by reducing the risk of ventilation-induced lung injury. However, inter-individual variability is a hallmark of ARDS and lung protection by PP might not be optimal in all patients. In the present study, we dynamically assessed physiologic effects of PP by Electrical Impedance Tomography (EIT) and identified predictors of improv...
Source: Minerva Anestesiologica - May 27, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Anesthesia and analgesia in the preterm infant is still something in between art and science.
Authors: Somaini M, Ingelmo P PMID: 32449340 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 27, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Erector spinae plane block for myofascial pain syndrome: only a short term relief?
Authors: Piraccini E, Calli M, Taddei S, Byrne H, Rocchi M, Maitan S PMID: 32449341 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 27, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

The use of lumbar plexus block with Shamrock technique and continuous sciatic nerve block for thigh amputation in high risk patient.
Authors: Gobbi F, Fusco P, Di Carlo S, Giachetti A PMID: 32449342 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 27, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

How do i manage cerebral vasospasm and delayed cerebral ischemia?
Authors: Gaspard N Abstract Delayed cerebral ischemia (DCI) is the leading cause of mortality and disability in patients who survived the initial bleed of subarachnoid hemorrhage. Currently available guidelines are based on expert opinions derived from small observational studies due to the lack of randomized controlled trials. In this review, we will review some of the available literature and describe our local protocols for prophylaxis, risk stratification, monitoring in patients at risk, including multimodal invasive monitoring, and interventions measures in patients with DCI. These protocols are largely in lin...
Source: Minerva Anestesiologica - May 24, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Postoperative sore throat and tracheal tube introducers.
Authors: Vaida S, Prozesky J PMID: 32441087 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 24, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Dexmedetomidine as a promise.
Authors: Meresse Z, Leone M PMID: 32441088 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 24, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Organ preservation for donation after circulatory death: combining in- situ and ex-situ strategies.
Authors: Argalious MY PMID: 32441089 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 24, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Epidural anesthesia is no longer the standard of care in abdominal surgery with ERAS. What are the alternatives?
CONCLUSIONS: Since ERAS was introduced, the advantages of epidural anesthesia vanished while the incidence of serious neurological complications is higher than previously thought. The authors conclude that epidural anesthesia in abdominal surgery has become less preferred, and is limited to patients and types of surgery known to be accompanied with difficult pain management. This requires the use of other methods for analgesia, such as intravenous ketamine, peripheral nerve blocks, continuous wound infiltration, intrathecal morphine, and intravenous, and non-invasive PCA. PMID: 32420713 [PubMed - as supplied by publish...
Source: Minerva Anestesiologica - May 19, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

The effectiveness of clavipectoral fascia plane block for analgesia after clavicle surgery: a report of five cases.
Authors: Atalay YO, Ciftci B, Ekinci M, Yesiltas S PMID: 32420714 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 19, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

The "liver patient": a challenging scenario for today's anesthesiologists.
The "liver patient": a challenging scenario for today's anesthesiologists. Minerva Anestesiol. 2020 May 18;: Authors: De Wolf AM, Biancofiore G PMID: 32420715 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 19, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Subxiphoid cardiac drainage pain managament: could ultrasound rectus sheath block be the answer?
Authors: Sepolvere G, Tedesco M, Fusco P, Scimia P, Donatiello V, Cristiano L PMID: 32420716 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 19, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Post-operative cognitive dysfunction: opportunities for interdisciplinary research.
Authors: Turnbull D PMID: 32420717 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 19, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Esophageal detection method may be a good choice to confirm endotracheal tube placement for patients with COVID-19 infection.
Authors: Wang Y, Ma WH PMID: 32400997 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 15, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Steroid injections for pain management in the COVID-19 era.
Authors: Piraccini E, Byrne H, Taddei S PMID: 32400998 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 15, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Managing chronic pain patients at the time of COVID-19 pandemic.
Authors: Coluzzi F, Marinangeli F, Pergolizzi J PMID: 32400999 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 15, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

First ultrastructural autoptic findings of SARS-Cov-2 in olfactory pathways and brainstem.
Authors: Bulfamante G, Chiumello D, Canevini MP, Priori A, Mazzanti M, Centanni S, Felisati G PMID: 32401000 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - May 15, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Microbiome: what intensivists should know.
Authors: Nakov R, Segal JP, Settanni CR, Bibbò S, Gasbarrini A, Cammarota G, Ianiro G Abstract The standard conditions of critical illness (including sepsis, acute respiratory distress syndrome, and multiorgan failure) cause enormous global mortality and a growing economic burden. Increasing evidence suggests that critical illness may be associated with loss of commensal microbes and overgrowth of potentially pathogenic and inflammatory bacteria. This state could be associated with poor outcomes. Therefore, microbiota-targeted interventions are potentially attractive novel treatment options. Although the pre...
Source: Minerva Anestesiologica - May 7, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Respiratory consequences of intra-abdominal hypertension.
Authors: Tonetti T, Cavalli I, Ranieri VM, Mascia L Abstract Intra-abdominal hypertension (IAH) is a common complication in critically ill patients that may lead to multiorgan failure and is associated to worse outcome. Respiratory failure is among the most important consequences of IAH and it is originated by different mechanisms, such as chest wall elastance increase, functional residual capacity reduction, compression atelectasis and lung edema formation through reduction in lymphatic drainage. Many experimental studies showed that total lung capacity and functional residual capacity can be decreased by 40% duri...
Source: Minerva Anestesiologica - May 7, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Perioperative cognitive function: must the poor get poorer?
Authors: Qu JZ, Alston TA PMID: 32304362 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - April 20, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Can goal-directed fluid therapy decrease the use of blood and hemoderivates in surgical patients?
Authors: Tomescu DR, Scarlatescu E, Bubenek-Turconi ŞI Abstract The purpose of Goal Directed Therapy (GDT) is to improve patient outcome by the optimization of hemodynamic status, as it is considered that many perioperative complications are related to microcirculatory disturbance due to an imbalance between oxygen delivery and consumption. The application of GDT protocols incorporating the assessment and optimization of patients' intravascular status should theoretically lead to a reduction in perioperative bleeding and transfusion requirements, as both hypervolemia and hypovolemia and their consequences such as ...
Source: Minerva Anestesiologica - April 8, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Comparison of the i-gelTM with the AuraGainTM laryngeal mask airways in patients with a simulated cervical immobilization: a randomized controlled trial.
This study was performed to compare the clinical performance of the i-gel with that of the AuraGain in patients with simulated cervical immobilization. METHODS: We conducted a prospective, randomized controlled trial in 104 patients undergoing general anaesthesia from June to September 2018 at the Seoul National University Hospital. Patients were randomly allocated to receive either the i-gel or the AuraGain device. A difficult airway was simulated using a cervical collar limiting the mouth opening and neck movement. The primary outcome was the initial oropharyngeal leak pressure. RESULTS: The rate of successful in...
Source: Minerva Anestesiologica - April 8, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Effects of anesthesia depth on postoperative cognitive function and inflammation: a systematic review and meta-analysis.
CONCLUSIONS: Light anesthesia was associated with a decrease in POD and may promote better neurocognitive function postoperatively in comparison with deep anesthesia. PMID: 32251571 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - April 8, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Donation after circulatory death: possible strategies for in-situ organ preservation.
We describe an innovative preservation strategy based on the combination of donor NRP for abdominal organ preservation and a normothermic open-lung approach with protective mechanical ventilation for lung preservation. PMID: 32251572 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - April 8, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Effects of deep neuromuscular block on surgical workspace conditions in laparoscopic bariatric surgery: a systematic review and meta-analysis of randomized controlled trials.
CONCLUSIONS: It was found that dNMB helps improve surgical space conditions in patients undergoing laparoscopic bariatric surgery whereas it fails to shorten procedure duration. More high-quality large-sampled RCTs are needed to confirm these results. The relationship between dNMB use and other clinical outcomes, such as complications occurrence, needs to be further investigated. PMID: 32251573 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - April 8, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Anesthesia timing for children undergoing therapeutic cardiac catheterization after upper respiratory infection: a prospective observational study.
Authors: Kan Z, Siyuan W, Mengqi L, Chi W, Liping S, Sen Z, Jie B, Mazhong Z, Jijian Z Abstract BACKGROUND: We aimed to analyze anesthesia timing and perioperative respiratory adverse event (PRAE) risk factors in children undergoing therapeutic cardiac catheterization after upper respiratory tract infection (URI). METHODS: We prospectively included children for elective therapeutic cardiac catheterization. Parents or legal guardians were asked to complete a questionnaire on the child's demographics, tobacco exposure, and URI symptoms. PRAEs (laryngospasm, bronchospasm, coughing, airway secretion, airway obstruc...
Source: Minerva Anestesiologica - April 8, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Pediatric pain review: what has happened since the First World Congress on Pediatric Pain in 1988? The past, the present and the future.
Authors: Lonnqvist PA Abstract The present text summarizes the development within the field of pediatric pain during the last 30 years, with a special focus on pediatric postoperative pain. Insights concerning pain ontogeny, how pain influences the neuro-endocrine stress response and the induction of a "pain memory" is discussed as well as established and new options with regards to treatment of postoperative pain. Lastly, some aspects concerning future development within this field is discussed. It is now well-established that even the unborn fetus reacts with behavioral responses indicative of pain and ...
Source: Minerva Anestesiologica - April 8, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Ultrasound-guided erector spinae plane block to avoid postoperative opioids in open abdominal aortic aneurysm repair.
Authors: Zani G, Righetti R, Piraccini E, Santonastaso DP, Terenzoni M, Gecele C, Baccarini FD, Fusari M PMID: 32251576 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - April 8, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Reply to: Direct oral anticoagulants and neuraxial block in elderly orthopedic patients: is it time to review guidelines?
Authors: Pavoni V, Gianesello L PMID: 32251577 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - April 8, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Calibration of risk scores: one model does not fill all.
Authors: Ranucci M PMID: 32251578 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - April 8, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

SIAARTI recommendations for the allocation of intensive care treatments in exceptional, resource-limited circumstances.
Authors: Vergano M, Bertolini G, Giannini A, Gristina GR, Livigni S, Mistraletti G, Riccioni L, Petrini F PMID: 32242647 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - April 5, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Anesthesiologists and their monitoring: benefits, limits and confusing factors.
Authors: Deflandre EP, Javillier BX PMID: 32191408 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - March 21, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Corrected and republished from: Regional anesthesia and antithrombotic agents: instructions for use.
Authors: Scibelli G, Maio L, Savoia G Abstract This corrects the article DOI: 10.23736/S0375-9393.16.11414-2. PMID: 32191409 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - March 21, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Effect of volatile anesthetics on mortality and clinical outcomes in patients undergoing coronary artery bypass grafting: a meta-analysis of randomized clinical trials.
CONCLUSIONS: There is no difference in the long- and short-term mortality and clinical outcomes between intraoperative use of volatile anesthetics and TIVA during CABG. However, volatile anesthetics may shorten the mechanical ventilation time. There is a need for high-quality multicenter RCTs that specifically assess factors that influence mortality and clinical outcomes. PMID: 32162897 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - March 13, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Clinical ethics at bedside in ICU: what difference does ethics consultation make?
Authors: Giannini A PMID: 32162898 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - March 13, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

A case of intractable hyperglycemia.
Authors: Romano GM, Cafiero T, De Robertis E PMID: 32162899 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - March 13, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Back and forth from basic science to clinical translation.
Authors: Pagliaro P PMID: 32162900 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - March 13, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

A new pressure guided management tool for epidural space detection: feasibility assessment in a clinical scenario.
CONCLUSIONS: The proposed mechatronic system successfully detected the LOR in the large part of cases using the configurations characterized by the best trade-off between system sensitivity and range of measurements. A non-significant increment of the procedure time is related to the use of the system. PMID: 32154680 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - March 12, 2020 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research