Messages from the Ricalor Study.
Authors: Apan A, Cuvas Apan O PMID: 26959384 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - March 10, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

STOP-bang questionnaire in the perioperative setting: striving for continuous improvement.
Authors: Corso RM, Petrini F, Sorbello M, Maitan S PMID: 26923750 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - March 1, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Time-dependent and independent neurophysiological indicators of prognosis in post-anoxic coma subjects treated by therapeutic hypothermia.
CONCLUSION: EEG is a reliable time-dependent predictor of a good outcome (within 12 hrs) and a poor outcome (after 72 hrs). SEP is a time-independent predictor of a poor outcome. PMID: 26883623 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - February 21, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Non-invasive ventilation and survival rates: the more, the better. A plea against its underuse.
Authors: Cabrini L, Landoni G PMID: 26883624 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - February 21, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Pitfalls of brain monitoring using NIRS device.
Authors: Taccone FS, Oddo M PMID: 26883625 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - February 21, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

How to improve communication quality with patients and relatives in the ICU.
Authors: Warrillow S, Farley KJ, Jones D Abstract The experience of intensive care for patients and their families is known to be very stressful and may result in both acute and chronic psychological problems that include sleep disturbance, depression, anxiety and post-traumatic stress disorder. While some non-modifiable risk factors for psychological harm are known, there are also a several modifiable risk factors that may be addressed using strategically planned interventions such as optimal communication techniques. Effective communication is increasingly being recognized as an essential non-technical skills for...
Source: Minerva Anestesiologica - February 21, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Patient-controlled analgesia: past, present and future.
Authors: Deflandre E, Jaucot J PMID: 26883748 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - February 21, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Influence of supraglottic airway device placement on cerebral hemodynamics.
CONCLUSION: SGD insertion and cuff inflation did not influence cerebral hemodynamics in anesthetized patients undergoing minor surgery. At normal etCO2 range, the CBF reduction with transient increase in PI was associated with anesthesia induction and not SGD insertion itself. PMID: 26859154 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - February 10, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Restrictive versus more liberal blood transfusions? The answer is in your heart.
Authors: Vincent JL, VAN DER Linden P PMID: 26859155 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - February 10, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Cycle asynchrony: always a concern during pressure ventilation!
Authors: Kacmarek RM, Villar J, Blanch L PMID: 26859156 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - February 10, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Are informational videos good for pediatric patients?
Authors: Pabelich CM PMID: 26847496 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - February 9, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

The role of anesthesia in the prevention of postoperative delirium: a systematic review.
CONCLUSIONS: Methodologically robust studies supporting strategies for preventing POD are still lacking. Based on our analysis, anesthesiologists should consider the intra-operative use of a depth of anesthesia monitor and the choice for a lighter sedation when possible. The administration of preventive medications should be considered very carefully. Considering the multifactorial nature of POD, however, the integration of effective preventive strategies into multidisciplinary programs is advisable and should be the target for future research. PMID: 26822815 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - January 31, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Insurance claims' of alleged anesthesiology malpractice in a spanish series.
Authors: Parera-Ruiz A, GóMEZ-DURáN EL, Martin-FUMADó C, Bisbe E, Arimany-Manso J PMID: 26822816 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - January 31, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Tetanus and Tako-Tsubo: is there a relationship?
Authors: Brunelli G, Tesoro S, Trotta A, Dentini N, Peduto VA PMID: 26822817 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - January 31, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Intravenous immunoglobins in sepsis - the potential risk of overinterpreting a well-done meta-analysis.
Authors: Leone M, Duclos G, Coopersmith CM PMID: 26822818 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - January 31, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

How should ethical committees promote research in critically ill patients?
Authors: Caironi P, Fumagalli R, Tognoni G PMID: 26822819 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - January 31, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

A year in review in Minerva Anestesiologica 2015.
Authors: Cavaliere F, Allegri M, Calderini E, Carassiti M, Coluzzi F, DI Marco P, Piastra M, Rossi M PMID: 26822820 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - January 31, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

A Year In Review In Minerva Anestesiologica 2015. Critical Care. Experimental and clinical studies.
Authors: Cavaliere F, Biancofiore G, Bignami EG, DE Robertis E, Giannini A, Grasso S, Scolletta S, Taccone FS, Terragni P PMID: 26818030 [PubMed - in process] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - January 30, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Cardiac dysfunction and circulating cardiac markers during sepsis.
Authors: Latini R, Caironi P, Masson S Abstract Among several alterations affecting the cardiovascular system during severe sepsis or septic shock, myocardial depression has been pointed out with increasing attention over the last 30 years as a frequent and often misdiagnosed clinical condition. As expected, patients with cardiac dysfunction during sepsis have a worse prognosis than those without. In the present review, we will first discuss the etiology, pathophysiology, monitoring and clinical manifestations of cardiac dysfunction in patients with severe sepsis or septic shock. Thereafter, we will briefly present...
Source: Minerva Anestesiologica - January 24, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Impact of AxotrackTM for ultrasound-guided central venous catheter insertion:a randomized placebo-controlled study conducted on inanimate manikin.
Authors: Alves M, Bigé N, Pichereau C, Baudel JL, Galbois A, Ait-Oufella H, Maury E PMID: 26744264 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - January 16, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

The heart of the art.
Authors: Carassiti M, Cataldo R PMID: 26744265 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - January 16, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Screening for sleep apnea in the perioperative setting: looking for the right compromise.
Authors: Sparkle T, Sridhar S, Corso RM, Castriotta R, Courtney S, Mullaly A, Hagberg CA, Cattano D PMID: 26744266 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - January 16, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

The quality and lifespan of guidelines.
Authors: Page VJ, Casarin A PMID: 26744267 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - January 16, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Risk factors for ventilator associated pneumonia due to KPC-producing Klebsiella pneumoniae in mechanically ventilated patients with tracheal and rectal colonization.
Authors: Sbrana F, Malacarne P, Bassetti M, Tascini C, Vegnuti L, Della Siega P, Ripoli A, Ansaldi F, Menichetti F Abstract BACKGROUND: To identify the risk factors for VAP due to KPC-producing Klebsiella pneumoniae development in ICU patients with documented rectal and tracheal colonization. METHODS: We performed a retrospective, matched case-control study in a medical-surgical ICU (January 2011 - December 2013) comparing 30 patients who developed KPC-Kp VAP during the ICU stay to 60 colonized patients not developing KPC-Kp VAP. Analysed risk factors included: age, sex, SAPS II and SOFA scores, co-morbidities,...
Source: Minerva Anestesiologica - January 16, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

How to advance prediction of postoperative delirium? A secondary analysis comparing three methods for very early assessment of elderly patients after surgery and early prediction of delirium.
Authors: Stukenberg S, Franck M, Spies CD, Neuner B, Myers I, Radtke FM Abstract BACKGROUND: Postoperative impairment of the cerebral function can appear immediately after general anesthesia and may be predictive for a postoperative delirium. We compared three tools assessing patients on recovery room admission in order to detect early signs of postoperative brain dysfunction: the Postanesthetic Recovery Score (PARS), the Richmond Agitation-Sedation Scale (RASS) and the Nursing Delirium Screening Scale (Nu-DESC). METHODS: Inclusion criteria of this secondary analysis of the randomized SuDoCo trial were: age &ge...
Source: Minerva Anestesiologica - January 16, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Validation of a novel index of hemorrhage using a lower body negative pressure shock model.
Authors: Vettorello M, Sher S, Santambrogio S, Calini A, Tardini F, Lippi M, Fumagalli R Abstract BACKGROUND: Vital signs are late indicators of blood loss in trauma patients. Indexed Heart to Arm Time (iHAT) is a non invasive index based on a modified pulse transit time (mPTT) indexed to the time between R waves on the electrocardiogram (RR interval). We aimed to investigate how early iHAT is able to detect central hypovolemia during the progression from mild to severe simulated hemorrhage induced by applying lower body negative pressure (LBNP). METHODS: Thirty healthy volunteers were enrolled. Central hypovol...
Source: Minerva Anestesiologica - January 16, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

I have a dream...
Authors: Basaranoglu G, Bakan M PMID: 26756379 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - January 16, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Red blood cell transfusion strategies in critically ill patients: lessons from recent randomized clinical studies.
Authors: Lelubre C, Vincent JL, Taccone FS Abstract Recently, Holst et al. (N Engl J Med 2014; 371:1381-1391) reported the results from a randomized, multicenter trial conducted in 32 northern European general intensive care units (ICUs), in which patients with septic shock were randomly assigned to receive a red blood cell transfusion when the hemoglobin (Hb) level was ≤ 7 g/dl ("lower threshold"; n=502) or ≤ 9 g/dl ("higher threshold"; n=496) throughout the ICU stay. Patients were excluded if they had an acute coronary syndrome, life-threatening bleeding, acute burn injury, had already b...
Source: Minerva Anestesiologica - January 16, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

The Linus blanket.
Authors: Rossi M PMID: 26756381 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - January 16, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Prediction of difficult intubation with direct laryngoscopy winded up in quicksand: how can we get out of it?
Authors: Caldiroli D, Cortellazzi P PMID: 26672796 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - December 20, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Mechanical resuscitation devices under special circumstances in the out of hospital setting.
Authors: Greif R PMID: 26672797 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - December 20, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Guiding principles for the development of legislation regulating the doctor- patient relationship and end-of-life decisions: a joint effort by believers and non-believers.
Authors: Antonelli M, Gristina GR PMID: 26634307 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - December 8, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Adjusting ventilator off-cycling in invasively ventilated COPD patients needs comprehensive adjustments.
Authors: Harnisch LO, Zippel C, Herrmann P, Quintel M, Moerer O Abstract INTRODUCTION: Patient-ventilator asynchrony that prolongs weaning and increases morbidity and mortality is common during invasive ventilation of patients with chronic obstructive pulmonary disease (COPD). In this context, the inspiratory cycling criteria (iCC) of the ventilator during assisted pressure support (PS) ventilation is a poorly acknowledged key factor. We investigated the changes of flow and pressure parame- ters that resulted from varying the iCC in a simulated COPD lung model. METHODS: A lung simulator was connected to an ICU ...
Source: Minerva Anestesiologica - December 5, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

NIRS brain-monitoring in septic patients?
Authors: Barbaz M, Ferrandière M PMID: 26630028 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - December 5, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Patients with severe ARDS already positioned prone: why don´t we leave them in the prone position during transport and CT scan?
Patients with severe ARDS already positioned prone: why don´t we leave them in the prone position during transport and CT scan? Minerva Anestesiol. 2015 Dec 1; Authors: Brederlau J, Wurmb T, Schwemmer U PMID: 26630029 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - December 5, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Blood-brain barrier permeability following traumatic brain injury.
CONCLUSION: Our results suggest that traumatic brain injury is associated with early focal increases in small molecular BBB-permeability. The results indicate that in the injured brain, capillary hydrostatic and oncotic pressures may influence edema formation. PMID: 26613239 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - December 1, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

The association between the ultrasound-guided Serratus Plane Block and PECS I Block can represent a valid alternative to conventional anesthesia in breast surgery in a seriously ill patient.
Authors: Fusco P, Scimia P, Marinangeli F, Pozone T, Petrucci E PMID: 26613240 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - December 1, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Betahistine reduces postoperative nausea and vomiting and dizziness after laparoscopic gynecological surgery.
Authors: Cho JS, Kim EJ, Lee JH, Kim SY, Kim JM, Byun JI, Nam EJ, Koo BN Abstract BACKGROUND: Patients undergoing laparoscopic gynecological surgery are at high risk of postoperative nausea and vomiting (PONV). We compared the antiemetic efficacy of ondansetron plus betahistine with that of ondansetron alone in this patient population. METHODS: In this randomized, double-blinded study, 168 patients were randomly allocated to receive placebo (O group) or betahistine 18 mg (OB group) orally 3 h before surgery and 24 h thereafter. In both groups, ondansetron 4 mg was administered at the end of surgery and 8 mg was...
Source: Minerva Anestesiologica - November 21, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Progress testing in intensive care medicine training: useful and feasible?!
This article provides a concise general background on the nature and use of progress testing, and touches upon potential strengths, and constraints regarding its potential implementation and use in the postgraduate intensive care medicine training programmes. PMID: 26576859 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - November 21, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Mechanical LUCAS resuscitation is effective, reduces physical workload and improves mental performance of helicopter emergency teams.
Authors: Rehatschek G, Muench M, Schenk I, Dittrich W, Schewe JC, Dirk C, Hering R Abstract BACKGROUND: Physical and mental workload during cardiopulmonary resuscitation (CPR) is challenging under extreme working conditions. We hypothesized that the mechanical chest- compression device LUCAS increases the effectiveness of CPR, decreases the physical workload and improves the mental performance of the emergency medical service (EMS) staff during simulated emergency helicopter flights. METHODS: During simulated helicopter flights 12 EMS teams performed manual or LUCAS- CPR on a manikin at random order. Compressio...
Source: Minerva Anestesiologica - November 21, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

"Italian Registry of Complications associated with Regional Anesthesia" (RICALOR). An incidence analysis from a prospective clinical survey.
CONCLUSIONS: We confirmed RA as generally safe, but monitoring and diagnosis, together with further research efforts, are needed to improve patients' care and clarify potential risk factors. PMID: 26584187 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - November 21, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Spinal epidural abscess: stay focused, stay tuned! A clinical report with negative neurological outcome from the "Italian Registry of Complications Associated with Regional Anesthesia - RICALOR".
Spinal epidural abscess: stay focused, stay tuned! A clinical report with negative neurological outcome from the "Italian Registry of Complications Associated with Regional Anesthesia - RICALOR". Minerva Anestesiol. 2015 Nov 18; Authors: Manassero A, Ugues S, Coletta G, Bugada D PMID: 26584188 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - November 21, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

The Impact of patient controlled analgesia on prognosis of patients receiving major abdominal surgery.
Authors: Peng L, Ren L, Qin P, Su M Abstract BACKGROUND: Post-operative pain is a major disease burden after surgery. Patient controlled analgesia has been wide used for pain management in surgical patients, yet, large-scaled studies are lacking to assess its impact on the prognosis of patients. METHODS: We prospectively enrolled patients who underwent major abdominal surgeries receiving patient controlled analgesia (PCA) and who received non-PCA analgesia for assessment of 60-day mortality, major post-operative complications using electronic medical chart system. Pain intensity was also assessed with visual an...
Source: Minerva Anestesiologica - November 21, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Organ donation after circulatory death (DCD) in Italy? Yes we can !
Authors: Nanni Costa A, Procaccio F PMID: 26584190 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - November 21, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Farewell to Giorgio Gambale.
Authors: PMID: 26588474 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - November 21, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Ultrasound evaluation of the stomach and gastric emptying in pregnant women at term: a case-control study.
CONCLUSION: In pregnant women at term, the stomach does not seem to be able to expand immediately after the meal. The transit of food is completed later than in not pregnant women. The ultrasound of the stomach allows identifying delays gastric emptying and highlighting patients at risk of aspiration. PMID: 26554613 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - November 14, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Closed-loop anesthesia: a systematic review.
Authors: Le Guen M, Liu N, Chazot T, Fischler M Abstract Automated anesthesia which may offer to the physician time to control hemodynamic and to supervise neurological outcome and which may offer to the patient safety and quality was till recently consider as a holy grail. But this field of research is now increasing in every component of general anesthesia (hypnosis, nociception, neuromuscular blockade) and literature describes some successful algorithms - single or multi closed-loop controller. The aim of these devices is to control a predefined target and to continuously titrate anesthetics whatever the patient...
Source: Minerva Anestesiologica - November 14, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Extracorporeal membrane oxygenation in avalanche victim with deep hypothermia and circulatory arrest.
Authors: Facchetti G, Carbuglia N, Bucci V, Taraschi F, Paparoni S, Gyra A, Marinangeli F PMID: 26544758 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - November 9, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Non-pharmacological interventions to reduce ICU-related psychological distress: a systematic review.
CONCLUSION: Evidence indicates that non-pharmacological approaches to reducing ICU distress, in particular psychological interventions, may be beneficial. The evidence base would be strengthened by the implementation of fully-powered studies using robust designs, that measure longer-term outcomes. (241). PMID: 26505225 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - October 30, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Melatonin and the future of critically ill patients' outcomes.
Authors: Morandi A, Brummel NE, Pandharipande P PMID: 26505226 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - October 30, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research