Efficacy of Liposomal Bupivacaine in Reducing Opioid Use After Posterior Lumbar Spinal Decompression and Fusion
CONCLUSION: The findings of this study suggest that the addition of liposomal bupivacaine to traditional pain management modalities can augment pain management for patients undergoing posterior lumbar surgery, as evidenced by the significant decrease in postoperative morphine milligram equivalents required. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38568003 | DOI:10.3928/01477447-20240325-07 (Source: Orthopedics)
Source: Orthopedics - April 3, 2024 Category: Orthopaedics Authors: Amber McClure Olivia C Silveri Megan Foddrell Karen Duteil Laura E Madar ász Christopher P Silveri Source Type: research
PBPK-PD model for predicting morphine pharmacokinetics, CNS effects and naloxone antagonism in humans
In conclusion, the pharmacokinetics and pharmacodynamics of morphine and M6G, antagonistic effects of naloxone against morphine-induced CNS effects may be successfully predicted using the developed PBPK-PD model based on the parameters derived from in vitro, in silico, or animal studies.PMID:38570601 | DOI:10.1038/s41401-024-01255-2 (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 3, 2024 Category: Drugs & Pharmacology Authors: Rui-Jing Mu Tian-Lei Liu Xiao-Dong Liu Li Liu Source Type: research
Efficacy of Liposomal Bupivacaine in Reducing Opioid Use After Posterior Lumbar Spinal Decompression and Fusion
CONCLUSION: The findings of this study suggest that the addition of liposomal bupivacaine to traditional pain management modalities can augment pain management for patients undergoing posterior lumbar surgery, as evidenced by the significant decrease in postoperative morphine milligram equivalents required. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38568003 | DOI:10.3928/01477447-20240325-07 (Source: Orthopedics)
Source: Orthopedics - April 3, 2024 Category: Orthopaedics Authors: Amber McClure Olivia C Silveri Megan Foddrell Karen Duteil Laura E Madar ász Christopher P Silveri Source Type: research
PBPK-PD model for predicting morphine pharmacokinetics, CNS effects and naloxone antagonism in humans
In conclusion, the pharmacokinetics and pharmacodynamics of morphine and M6G, antagonistic effects of naloxone against morphine-induced CNS effects may be successfully predicted using the developed PBPK-PD model based on the parameters derived from in vitro, in silico, or animal studies.PMID:38570601 | DOI:10.1038/s41401-024-01255-2 (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 3, 2024 Category: Drugs & Pharmacology Authors: Rui-Jing Mu Tian-Lei Liu Xiao-Dong Liu Li Liu Source Type: research
Efficacy of Liposomal Bupivacaine in Reducing Opioid Use After Posterior Lumbar Spinal Decompression and Fusion
CONCLUSION: The findings of this study suggest that the addition of liposomal bupivacaine to traditional pain management modalities can augment pain management for patients undergoing posterior lumbar surgery, as evidenced by the significant decrease in postoperative morphine milligram equivalents required. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38568003 | DOI:10.3928/01477447-20240325-07 (Source: Orthopedics)
Source: Orthopedics - April 3, 2024 Category: Orthopaedics Authors: Amber McClure Olivia C Silveri Megan Foddrell Karen Duteil Laura E Madar ász Christopher P Silveri Source Type: research
Efficacy of Liposomal Bupivacaine in Reducing Opioid Use After Posterior Lumbar Spinal Decompression and Fusion
CONCLUSION: The findings of this study suggest that the addition of liposomal bupivacaine to traditional pain management modalities can augment pain management for patients undergoing posterior lumbar surgery, as evidenced by the significant decrease in postoperative morphine milligram equivalents required. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38568003 | DOI:10.3928/01477447-20240325-07 (Source: Orthopedics)
Source: Orthopedics - April 3, 2024 Category: Orthopaedics Authors: Amber McClure Olivia C Silveri Megan Foddrell Karen Duteil Laura E Madar ász Christopher P Silveri Source Type: research
Efficacy of Liposomal Bupivacaine in Reducing Opioid Use After Posterior Lumbar Spinal Decompression and Fusion
CONCLUSION: The findings of this study suggest that the addition of liposomal bupivacaine to traditional pain management modalities can augment pain management for patients undergoing posterior lumbar surgery, as evidenced by the significant decrease in postoperative morphine milligram equivalents required. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38568003 | DOI:10.3928/01477447-20240325-07 (Source: Orthopedics)
Source: Orthopedics - April 3, 2024 Category: Orthopaedics Authors: Amber McClure Olivia C Silveri Megan Foddrell Karen Duteil Laura E Madar ász Christopher P Silveri Source Type: research
Efficacy of Liposomal Bupivacaine in Reducing Opioid Use After Posterior Lumbar Spinal Decompression and Fusion
CONCLUSION: The findings of this study suggest that the addition of liposomal bupivacaine to traditional pain management modalities can augment pain management for patients undergoing posterior lumbar surgery, as evidenced by the significant decrease in postoperative morphine milligram equivalents required. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38568003 | DOI:10.3928/01477447-20240325-07 (Source: Orthopedics)
Source: Orthopedics - April 3, 2024 Category: Orthopaedics Authors: Amber McClure Olivia C Silveri Megan Foddrell Karen Duteil Laura E Madar ász Christopher P Silveri Source Type: research
Efficacy of Liposomal Bupivacaine in Reducing Opioid Use After Posterior Lumbar Spinal Decompression and Fusion
CONCLUSION: The findings of this study suggest that the addition of liposomal bupivacaine to traditional pain management modalities can augment pain management for patients undergoing posterior lumbar surgery, as evidenced by the significant decrease in postoperative morphine milligram equivalents required. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38568003 | DOI:10.3928/01477447-20240325-07 (Source: Orthopedics)
Source: Orthopedics - April 3, 2024 Category: Orthopaedics Authors: Amber McClure Olivia C Silveri Megan Foddrell Karen Duteil Laura E Madar ász Christopher P Silveri Source Type: research
Efficacy of Liposomal Bupivacaine in Reducing Opioid Use After Posterior Lumbar Spinal Decompression and Fusion
CONCLUSION: The findings of this study suggest that the addition of liposomal bupivacaine to traditional pain management modalities can augment pain management for patients undergoing posterior lumbar surgery, as evidenced by the significant decrease in postoperative morphine milligram equivalents required. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38568003 | DOI:10.3928/01477447-20240325-07 (Source: Orthopedics)
Source: Orthopedics - April 3, 2024 Category: Orthopaedics Authors: Amber McClure Olivia C Silveri Megan Foddrell Karen Duteil Laura E Madar ász Christopher P Silveri Source Type: research
Efficacy of Liposomal Bupivacaine in Reducing Opioid Use After Posterior Lumbar Spinal Decompression and Fusion
CONCLUSION: The findings of this study suggest that the addition of liposomal bupivacaine to traditional pain management modalities can augment pain management for patients undergoing posterior lumbar surgery, as evidenced by the significant decrease in postoperative morphine milligram equivalents required. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38568003 | DOI:10.3928/01477447-20240325-07 (Source: Orthopedics)
Source: Orthopedics - April 3, 2024 Category: Orthopaedics Authors: Amber McClure Olivia C Silveri Megan Foddrell Karen Duteil Laura E Madar ász Christopher P Silveri Source Type: research
Efficacy of Liposomal Bupivacaine in Reducing Opioid Use After Posterior Lumbar Spinal Decompression and Fusion
CONCLUSION: The findings of this study suggest that the addition of liposomal bupivacaine to traditional pain management modalities can augment pain management for patients undergoing posterior lumbar surgery, as evidenced by the significant decrease in postoperative morphine milligram equivalents required. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38568003 | DOI:10.3928/01477447-20240325-07 (Source: Orthopedics)
Source: Orthopedics - April 3, 2024 Category: Orthopaedics Authors: Amber McClure Olivia C Silveri Megan Foddrell Karen Duteil Laura E Madar ász Christopher P Silveri Source Type: research
Efficacy of Liposomal Bupivacaine in Reducing Opioid Use After Posterior Lumbar Spinal Decompression and Fusion
CONCLUSION: The findings of this study suggest that the addition of liposomal bupivacaine to traditional pain management modalities can augment pain management for patients undergoing posterior lumbar surgery, as evidenced by the significant decrease in postoperative morphine milligram equivalents required. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38568003 | DOI:10.3928/01477447-20240325-07 (Source: Orthopedics)
Source: Orthopedics - April 3, 2024 Category: Orthopaedics Authors: Amber McClure Olivia C Silveri Megan Foddrell Karen Duteil Laura E Madar ász Christopher P Silveri Source Type: research
Efficacy of Liposomal Bupivacaine in Reducing Opioid Use After Posterior Lumbar Spinal Decompression and Fusion
CONCLUSION: The findings of this study suggest that the addition of liposomal bupivacaine to traditional pain management modalities can augment pain management for patients undergoing posterior lumbar surgery, as evidenced by the significant decrease in postoperative morphine milligram equivalents required. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38568003 | DOI:10.3928/01477447-20240325-07 (Source: Orthopedics)
Source: Orthopedics - April 3, 2024 Category: Orthopaedics Authors: Amber McClure Olivia C Silveri Megan Foddrell Karen Duteil Laura E Madar ász Christopher P Silveri Source Type: research
Efficacy of Liposomal Bupivacaine in Reducing Opioid Use After Posterior Lumbar Spinal Decompression and Fusion
CONCLUSION: The findings of this study suggest that the addition of liposomal bupivacaine to traditional pain management modalities can augment pain management for patients undergoing posterior lumbar surgery, as evidenced by the significant decrease in postoperative morphine milligram equivalents required. [Orthopedics. 202x;4x(x):xx-xx.].PMID:38568003 | DOI:10.3928/01477447-20240325-07 (Source: Orthopedics)
Source: Orthopedics - April 3, 2024 Category: Orthopaedics Authors: Amber McClure Olivia C Silveri Megan Foddrell Karen Duteil Laura E Madar ász Christopher P Silveri Source Type: research
