What Has A.I. In Medicine Ever Done For Us? At Least 45 Things!
Remember Monty Python’s
brilliant Life of Brian movie scene where the Palestinian insurgent commando,
planning the abduction of Pilate’s wife in return for all the horrors they had
to endure from the Roman Empire, asks the rhetorical question: what have the
Romans ever done for us? With the hype and overmarketing, not to speak about
the fears around A.I, we asked the same question. What has A.I. in medicine
ever done for us? Well, we found at least 45 things.
I have 45 responses to
the pressing question on everyone’s mind who is interested in healthcare but
tired of the hype or the doomsday
scenarios around A.I.: ...
Source: The Medical Futurist - May 28, 2019 Category: Information Technology Authors: nora Tags: Artificial Intelligence in Medicine Future of Medicine administration AI cancer diagnostics digital health digital health technology Healthcare Innovation medical medical imaging Radiology treatment Source Type: blogs
Playback Heart Sounds: The eKuore Pro Digital Stethoscope Review
The white coat, the stethoscope, and the physician are inseparable as of yet. While artificial intelligence promises to become the next symbol of medicine, the eKuore Pro “only” aims to bring a much needed revamp of this ever-useful, iconic medical instrument. We found this wireless digital stethoscope to be fairly easy to use and feature-rich despite being remarkably heavier and pricier than conventional stethoscopes. If you want to know a pinch more detail about how the eKuore Pro performed, read our digital stethoscope review below.
From Vet to Med
The very mention of the word ‘doctor’ might elici...
Source: The Medical Futurist - May 14, 2019 Category: Information Technology Authors: nora Tags: Health Sensors & Trackers Portable Diagnostics device digital digital health digital stethoscope digital technology future heart Innovation medstudent review teaching Source Type: blogs
Fight Aging! Newsletter, May 13th 2019
In this study, a significant (30%) increase in maximum lifespan of mice was found after nonablative transplantation of 100 million nucleated bone marrow (BM) cells from young donors, initiated at the age that is equivalent to 75 years for humans. Moreover, rejuvenation was accompanied by a high degree of BM chimerism for the nonablative approach. Six months after the transplantation, 28% of recipients' BM cells were of donor origin. The relatively high chimerism efficiency that we found is most likely due to the advanced age of our recipients having a depleted BM pool.
In addition to the higher incorporation rates, ...
Source: Fight Aging! - May 12, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Bioengineered Viruses Used to Kill Antibiotic-Resistant Infection
Scientists at the Howard Hughes Medical Institute have achieved a world’s first of beating a bacterial infection using an engineered virus. This was done in a 15-year-old girl with cystic fibrosis who had a severe case of Mycobacterium.
The girl received a double lung transplant, but then developed the infection that antibiotics could not kill. The infection spread through the body, even developing into nodules over the skin.
As a last resort she was injected with bacteriophages, which are viruses that infect bacteria. These viruses were gathered as part of Howard Hughes Medical Institute’s SEA-PHAGES program, ...
Source: Medgadget - May 10, 2019 Category: Medical Devices Authors: Editors Tags: Genetics Medicine Public Health Surgery Source Type: blogs
Fight Aging! Newsletter, May 6th 2019
This study shows that mRNA levels of the aging related lamin A splice variant progerin, associated with premature aging in HGPS, were significantly upregulated in subjects with BMI ≥ 25 kg/m2. Moreover, our data revealed a significantly positive correlation of BMI with progerin mRNA. These data provide to our knowledge for the first-time evidence for a possible involvement of progerin in previously observed accelerated aging of overweight and obese individuals potentially limiting their longevity. Our results also showed that progerin mRNA was positively correlated with C-reactive protein (CRP). This might suggest an ass...
Source: Fight Aging! - May 5, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Is it Time for the DNE: Do Not ECMO
by Craig Klugman, Ph.D.
In the last few years, the hospital where I serve on the ethics committee has seen a dramatic uptick in the number of patients placed on extracorporeal membrane oxygenation (ECMO). ECMO is an amazing technology because it can maintain a body even after “severe neurologic impairment or multiorgan failure”. With its ability to replace heart and lung function, a body can be maintained long after the heart, lungs, and even brain have failed.
In ECMO, the machine replaces the lungs (and sometimes the heart).… (Source: blog.bioethics.net)
Source: blog.bioethics.net - May 1, 2019 Category: Medical Ethics Authors: Craig Klugman Tags: End of Life Care Featured Posts Organ Transplant & Donation DNE ECMO Source Type: blogs
XVIVO Perfusion System for Donor Lung Preservation and Assessment Finally Approved by FDA
XVIVO Perfusion, a company based out in Göteborg, Sweden, has been approved to introduce its Xvivo Perfusion System in the United States to effectively renew lungs that would otherwise would not be good enough for transplantation. The system ventilates, oxygenates, and pumps the Steen Solution Perfusate, a buffered extracellular solution, through the donor lungs while they’re inside the device. It essentially keeps the lungs alive and breathing independent of a human body. Since organs are typically cooled, packed, and rapidly shipped after harvesting, they’re not really kept alive and end up degrading quickly...
Source: Medgadget - May 1, 2019 Category: Medical Devices Authors: Editors Tags: Cardiac Surgery Source Type: blogs
TAVR: Aortic valve replacement without open-heart surgery
There has been a flurry of news recently about a procedure called trans-catheter aortic valve replacement (TAVR) for the treatment of the common heart condition aortic stenosis (AS). You may even know people who have had this procedure performed.
What exactly is TAVR? And what’s all the excitement about?
What is aortic stenosis?
First, it’s important to understand the condition that TAVR is designed to treat, aortic stenosis. The aortic valve is the last structure of the heart through which blood passes before entering the aorta and circulating throughout the body. The aortic valve has three flaps, called leaflets, tha...
Source: Harvard Health Blog - April 29, 2019 Category: Consumer Health News Authors: Pinak B. Shah, MD Tags: Health Heart Health Surgery Source Type: blogs
Fight Aging! Newsletter, April 22nd 2019
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
This content is...
Source: Fight Aging! - April 21, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Ultraviolet and Red Light Kill Infections in Donor Organs
Donor organs are hard to come by partially because of ischemic damage, physical damage, presence of infection, and other reasons. Researcher at the University of Toronto in Canada and University of São Paulo in Brazil have developed a method of getting rid of bacteria and viruses from donor organs using only light.
The technique involves first removing all donor blood from the organ, running a preservation liquid through the organ, and illuminating organs using ultraviolet and red light for about a half hour or so. In order to boost effectiveness, a photosensitizing drug is introduced into the liquid that is activated by ...
Source: Medgadget - April 15, 2019 Category: Medical Devices Authors: Editors Tags: News Source Type: blogs
Fight Aging! Newsletter, April 15th 2019
In this study, we found that senescent chondrocytes isolated from OA patients secrete more EVs compared with nonsenescent chondrocytes. These EVs inhibit cartilage ECM deposition by healthy chondrocytes and can induce a senescent state in nearby cells. We profiled the miR and protein content of EVs isolated from the synovial fluid of OA joints from mice with SnCs. After treatment with a molecule to remove SnCs, termed a senolytic, the composition of EV-associated miR and protein was markedly altered. The senolytic reduced OA development and enhanced chondrogenesis, and these were attributable to several specific differenti...
Source: Fight Aging! - April 14, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Data Annotators: The Unsung Heroes Of Artificial Intelligence Development
How do you create a smart algorithm? Where and how do you get the data for it? What do you need for a pattern recognizing program to work well and what are the challenges? Nowadays, everyone seems to be building artificial intelligence-based software, also in healthcare, but no one talks about one of the most important aspects of the work: data annotation and the people who are undertaking this time-consuming, rather monotonous task without the flare that usually encircles A.I. Without their dedicated work, it is impossible to develop algorithms, so we thought it is time to sing an ode to the superheroes of algorithm devel...
Source: The Medical Futurist - April 9, 2019 Category: Information Technology Authors: nora Tags: Artificial Intelligence in Medicine Future of Medicine AI algorithm annotation data data annotation doctor Health Healthcare physician smart algorithm technology Source Type: blogs
What Will Being Healthy Mean In The Future?
The objective is not “just” being healthy anymore
but also being in the best shape possible. The healthy lifestyle craze that
started in the 1980s is augmented with technologies and penetrates every area and
moment of life.
In his book, 21
Lessons for the 21st Century, Yuval Noah Harari argues that as technology encompasses every tiny part
of our health, we will gradually let technology
take over our decision-making capacities. In a couple of decades, tiny sensors and big data
might tell us whether we are sick or healthy. Medical decisions in our life won’t rely on our feelings of illness or
wellness, or even on t...
Source: The Medical Futurist - April 6, 2019 Category: Information Technology Authors: nora Tags: Artificial Intelligence in Medicine Bioethics Health Sensors & Trackers AI doctor dystopia future Healthcare healthy healthy lifestyle history history of medicine Innovation patient philosophy progress technology Source Type: blogs
Fight Aging! Newsletter, March 25th 2019
This study defines a new clinically relevant concept of T-cell senescence-mediated inflammatory responses in the pathophysiology of abnormal glucose homeostasis. We also found that T-cell senescence is associated with systemic inflammation and alters hepatic glucose homeostasis. The rational modulation of T-cell senescence would be a promising avenue for the treatment or prevention of diabetes.
Intron Retention via Alternative Splicing as a Signature of Aging
https://www.fightaging.org/archives/2019/03/intron-retention-via-alternative-splicing-as-a-signature-of-aging/
In recent years researchers have in...
Source: Fight Aging! - March 24, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, March 18th 2019
This study provides a possible reason why genes carrying health risks have persisted in human populations. The second found evidence for multiple variants in genes related to ageing that exhibited antagonistic pleiotropic effects. They found higher risk allele frequencies with large effect sizes for late-onset diseases (relative to early-onset diseases) and an excess of variants with antagonistic effects expressed through early and late life diseases.
There also exists other recent tangible evidence of antagonistic pleiotropy in specific human genes. The SPATA31 gene has been found under strong positive genomic sele...
Source: Fight Aging! - March 17, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
