Fight Aging! Newsletter, May 11th 2020
In this study, we found that older nematodes have higher ROS levels. Interestingly, after hydrogen treatment, the ROS levels were significantly decreased, and hydrogen could significantly extend the lifespans of the N2, sod-3 and sod-5 mutant strains, by approximately 22.7%, 9.5%, and 8.7%, respectively. In addition, aging is regulated by a variety of pathways, such as the insulin signaling pathway, the rapamycin target signaling pathway, and the caloric restriction pathway. However, our results showed that the lifespans of the daf-2 and daf-16 strains, in which these pathways are upregulated, were not affected afte...
Source: Fight Aging! - May 10, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Top 5 Practical Digital Health Technologies in the Fight Against COVID-19: An Infographic
We reported on how digital health came to the spotlight early on. As we learn more about the disease, we see digital health technologies increasingly getting adopted in this context. We created an infographic to summarize all the digital health tech efforts against this pandemic.  This will help caregivers and policymakers understand how we can rely on technologies in the fight against the novel coronavirus; and which sectors and phases of healthcare are aided by digital health. In our infographic, listed on the Y-axis are the technologies making a significant impact in the fight against the pandemic. Indicated ...
Source: The Medical Futurist - May 7, 2020 Category: Information Technology Authors: Prans Tags: Future of Medicine Telemedicine & Smartphones Virtual Reality digital health infographics covid covid19 Source Type: blogs

Fight Aging! Newsletter, May 4th 2020
The objective is to start treating chronic diseases from the root and not the symptoms of the disease. As we are starting to enroll patients in "senolytics-clinical trials," it will be imperative to assess if senolysis efficiently targets the primary cause of disease or if it works best in combination with other drugs. Additional basic science research is required to address the fundamental role of senescent cells, especially in the established contexts of disease. Notes on Self-Experimentation with Sex Steroid Ablation for Regrowth of the Thymus https://www.fightaging.org/archives/2020/04/notes-on-self-experi...
Source: Fight Aging! - May 3, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

COVID-19: Physicians in Shackles
By ANISH KOKA, MD A number of politically tinged narratives have divided physicians during the pandemic. It would be unfortunate if politics obscured the major problem brought into stark relief by the pandemic: a system that marginalizes physicians and strips them of agency. In practices big and small, hospital-employed or private practice, nursing homes or hospitals, there are serious issues raising their heads for doctors and their patients. No masks for you When I walked into my office Thursday, March 12th, I assembled the office staff for the first time to talk about COVID.  The prior weekend had been awa...
Source: The Health Care Blog - May 2, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Medical Practice Physicians Anish Koka medical autonomy Pandemic Source Type: blogs

Adding Voice to Respiratory and Cardiovascular Disease Diagnosis: Interview with Prof. Elad Maor
The field of telehealth is growing thanks to the steady growth in supportive technology and the need for remote monitoring, assessment, diagnosis, and testing. Voice is unique to every individual due to people’s anatomical differences, which makes for a powerful tool when working remotely. Vocalis Health is a company that uses machine learning and artificial intelligence to identify biomarkers in voice recordings. The company’s technology has been successfully used to identify mortality and hospitalization among heart failure patients. Vocalis is now adapting their technology to understand the associati...
Source: Medgadget - April 29, 2020 Category: Medical Devices Authors: Rukmani Sridharan Tags: Cardiology Diagnostics Exclusive Public Health Source Type: blogs

Beware the COVID-tech Cowboys
This article originally appeared on the Hardian Health blog here. The post Beware the COVID-tech Cowboys appeared first on The Health Care Blog. (Source: The Health Care Blog)
Source: The Health Care Blog - April 22, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Uncategorized Source Type: blogs

Left ventricular assist device (LVAD)
Left ventricular assist device is used to support the failing left ventricle when it is refractory to guideline directed medical therapy. It can be either a bridge to cardiac transplantation or a destination therapy. In general, cardiac transplantation offers better long term surival compared to LVAD according data available from devices except the most recent. As per the The Registry of the International Society for Heart and Lung Transplantation: Thirty-fourth Adult Heart Transplantation Report-2017 [1], there were 126,753 pediatric and adult heart transplants between 1982 and June 2015. Median survival was 10.7 years i...
Source: Cardiophile MD - April 16, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiac Surgery LVAD Source Type: blogs

The (Sober) State of Artificial Intelligence in the Fight Against COVID-19
If you ask us at The Medical Futurist about the importance of artificial intelligence in healthcare, we will have a lot to talk about. We’ve seen how it could solve alarm fatigue in hospitals. We’ve analyzed the unusual associations the technology discovered in medicine. We believe it will usher the real era of the Art of Medicine. Dr. Meskó even embarked on a journey to better understand the language of A.I. So of course, with the COVID-19 pandemic, we had to explore the contribution of A.I. in this public health crisis. We came across promising endeavours involving such algorithms from mining for insights through...
Source: The Medical Futurist - April 14, 2020 Category: Information Technology Authors: Prans Tags: Artificial Intelligence Future of Medicine digital health coronavirus covid covid19 Source Type: blogs

Fight Aging! Newsletter, April 13th 2020
This study is par for the course, looking at Japanese Olympic participants. Interestingly, it hints at the upper end of the dose-response curve for physical activity, in that a longer career as a professional athlete may be detrimental in comparison to lesser degrees of exercise and training. From this large, retrospective cohort study targeting 3546 Japanese Olympic athletes, we observed significant lower mortality among Olympians compared with the Japanese general population. The overall standardised mortality ratio (SMR) was 0.29. The results were consistent with previous studies conducted in other non-Asian co...
Source: Fight Aging! - April 12, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

‘Sophie’s Choice’ in the time of coronavirus: Deciding who gets the ventilator
Three otherwise healthy patients go to the emergency department with severe acute respiratory failure. Only one ventilator, required to sustain life until the worst of the coronavirus infection has passed, is available. Who gets the vent? That’s what “A Framework for Rationing Ventilators and Critical Care Beds During the COVID-19 Pandemic,” a Viewpoint just published in the Journal of the American Medical Association (JAMA), addresses. Douglas White, MD, MAS, Endowed Chair for Ethics in Critical Care Medicine at the University of Pittsburgh School of Medicine ...
Source: blog.bioethics.net - April 6, 2020 Category: Medical Ethics Authors: Bioethics Today Tags: Health Care Author: Lewis syndicated Source Type: blogs

Fight Aging! Newsletter, April 6th 2020
This study delves into the mechanisms by which a short period of fasting can accelerate wound healing. Fasting triggers many of the same cellular stress responses, such as upregulated autophagy, as occur during the practice of calorie restriction. It isn't exactly the same, however, so it is always worth asking whether any specific biochemistry observed in either case does in fact occur in both situations. In particular, the period of refeeding following fasting appears to have beneficial effects that are distinct from those that occur while food is restricted. Multiple forms of therapeutic fasting have been repor...
Source: Fight Aging! - April 5, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Getting Ready to Confront the Unthinkable
by Arthur Caplan, Ph.D. Rationing  has always been present in the American health care system.  Some poor individuals have not had access to certain treatments due to a lack of health insurance or hospitals not willing to accept them if they cannot pay.  And those in the transplant field have had to contend for decades with a shortage of organs forcing organized rationing in which many more die than benefit from access to a life-saving liver, heart or lung.  Emergency medicine personnel in big hospitals drill frequently on how to triage after a terrorist attack, a huge chemical plant explosion, an earthquake or other d...
Source: blog.bioethics.net - March 31, 2020 Category: Medical Ethics Authors: Arthur Caplan Tags: Ethics Featured Posts Public Health #diaryofaplagueyear COVID-19 rationing Rationing/ Resource Allocation Source Type: blogs

Can AI diagnose COVID-19 on CT scans? Can humans?
Vidur Mahajan Vasanth Venugopal By VASANTH VENUGOPAL MD and VIDUR MAHAJAN MBBS, MBA What can Artificial Intelligence (AI) do? AI can, simply put, do two things – one, it can do what humans can do. These are tasks like looking at CCTV cameras, detecting faces of people, or in this case, read CT scans and identify ‘findings’ of pneumonia that radiologists can otherwise also find – just that this happens automatically and fast. Two, AI can do things that humans can’t do – like telling you the exact time it would take you to go from point A to point B (i.e. Google maps), or like in this case, diagnose C...
Source: The Health Care Blog - March 23, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Artificial Intelligence COVID-19 Health Tech AI coronavirus CT scans Pandemic Radiology Vasanth Venugopal Vidur Mahajan Source Type: blogs

Fight Aging! Newsletter, March 23rd 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - March 22, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

I ’ve been on a ventilator before, so I’d like to sit this pandemic out
I have bled out during emergency surgery and been revived by the expert trauma and transplant team who raced into my operating room. I have had liter upon liter of donated blood transfused into my grey lifeless body. I survived months on a ventilator in an intensive care unit. I have had my lungs fill […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 19, 2020 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/lisa-goodman-helfand" rel="tag" > Lisa Goodman-Helfand < /a > < /span > Tags: Conditions COVID-19 coronavirus Infectious Disease Source Type: blogs