Fight Aging! Newsletter, April 6th 2020
This study delves into the mechanisms by which a short period of fasting can accelerate wound healing. Fasting triggers many of the same cellular stress responses, such as upregulated autophagy, as occur during the practice of calorie restriction. It isn't exactly the same, however, so it is always worth asking whether any specific biochemistry observed in either case does in fact occur in both situations. In particular, the period of refeeding following fasting appears to have beneficial effects that are distinct from those that occur while food is restricted.
Multiple forms of therapeutic fasting have been reported regarding their efficacy to improve health (decreasing body fat and blood pressure, promoting stem cell function and regeneration, reversing immunosuppression, suppressing inflammation, etc.), delay aging and extend life span. Recently, it was shown that fasting for 48 h during a 4-day observation period after stroke was able to augment angiogenesis in ischemic brain and alleviate cerebral ischemic injury in mice; periodic fasting (a 48-hour period of fasting per week for one month) resulted in reduced cortical atrophy and long-term neurobehavioral improvement. Nonetheless, the regulatory molecular mechanism by which fasting affects angiogenesis still remains unclear.
Here, we generated full-thickness excisional or burn skin wounds in streptozotocin-induced diabetic mice and normal mice, respectively, and determined whether fasting prior to or aft...
Source: Fight Aging! - Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
More News: Acromegaly | Acute Leukemia | African Health | Alzheimer's | Biochemistry | Biotechnology | Brain | Brain Cancers | Burns | Cancer | Cancer & Oncology | Cancer Therapy | Cardiology | Chemistry | China Health | Chronic Leukemia | Chronic Obstructive Pulmonary | Conferences | COVID-19 | Databases & Libraries | Dementia | Dermatology | Diabetes | Diets | Eating Disorders & Weight Management | Economy | Endocrinology | Environmental Health | Epidemiology | Epithelial Cancer | Finland Health | Fish | Fortamet | Fruit | Gastroschisis Repair | Genetics | Geriatrics | Heart | Heart Attack | Heart Disease | Heart Transplant | HIV AIDS | Hormones | Hypertension | Immunotherapy | Infectious Diseases | Interstitial Lung Disease | Ischemic Stroke | Italy Health | Japan Health | Kidney Transplant | Kidney Transplantation | Laboratory Medicine | Learning | Lemon Fruit | Leukemia | Liver | Liver Transplant | Lung Transplant | Lyme Disease | Materials Science | Men | Metformin | Mitochondria | Mitochondrial Disease | Molecular Biology | Neurology | Neuroscience | Nutrition | Obesity | Oral Cancer | Orthopaedics | Osteoporosis | Pandemics | Peripheral Neuropathy | Probiotics | Research | Scleroderma | Skin | Smokers | Sports Medicine | Statistics | Stem Cell Therapy | Stem Cells | Stroke | Study | Toxicology | Transplant Surgery | Transplants | Universities & Medical Training | Urology & Nephrology