Fight Aging! Newsletter, April 6th 2020

This study delves into the mechanisms by which a short period of fasting can accelerate wound healing. Fasting triggers many of the same cellular stress responses, such as upregulated autophagy, as occur during the practice of calorie restriction. It isn't exactly the same, however, so it is always worth asking whether any specific biochemistry observed in either case does in fact occur in both situations. In particular, the period of refeeding following fasting appears to have beneficial effects that are distinct from those that occur while food is restricted. Multiple forms of therapeutic fasting have been reported regarding their efficacy to improve health (decreasing body fat and blood pressure, promoting stem cell function and regeneration, reversing immunosuppression, suppressing inflammation, etc.), delay aging and extend life span. Recently, it was shown that fasting for 48 h during a 4-day observation period after stroke was able to augment angiogenesis in ischemic brain and alleviate cerebral ischemic injury in mice; periodic fasting (a 48-hour period of fasting per week for one month) resulted in reduced cortical atrophy and long-term neurobehavioral improvement. Nonetheless, the regulatory molecular mechanism by which fasting affects angiogenesis still remains unclear. Here, we generated full-thickness excisional or burn skin wounds in streptozotocin-induced diabetic mice and normal mice, respectively, and determined whether fasting prior to or aft...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs

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With COVID-19 becoming the number one priority for researchers around the globe, Parham Hashemi describes his role in overseeing the new trials being launched during the pandemic.
Source: The Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 30 May 2020Source: Indian Heart JournalAuthor(s): Aditya Kapoor, Rakesh Yadav
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Getty Images ... Hair salons, restaurants and retail shops are slowly reopening for business in communities throughout the country. ... And this summer many pools will join them, contingent on guid...
Source: AARP.org News - Category: American Health Source Type: news
Publication date: Available online 30 May 2020Source: Nanomedicine: Nanotechnology, Biology and MedicineAuthor(s): Renjie Wang, Zhengwei Cao, Lan Wei, Lin Bai, Hui Wang, Shiyi Zhou, Shuyue Zhan, Bin Ji, Zibo Li, Shi Gao, Jin Xie, Qingjie Ma
Source: Nanomedicine: Nanotechnology, Biology and Medicine - Category: Nanotechnology Source Type: research
Publication date: Available online 30 May 2020Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Yi Qu, He-Ying Hu, Ya-Nan Ou, Xue-Ning Shen, Wei Xu, Zuo-Teng Wang, Qiang Dong, Lan Tan, Jin-Tai Yu
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Publication date: Available online 30 May 2020Source: Obesity Research &Clinical PracticeAuthor(s): Chiaki Tanaka, Mark S. Tremblay, Masayuki Okuda, Shigeru Inoue, Shigeho Tanaka
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Publication date: Available online 30 May 2020Source: International Journal for Parasitology: Parasites and WildlifeAuthor(s): Guillermo Salgado-Maldonado, Juan Manuel Caspeta-Mandujano, Emilio Martínez-Ramírez, Jesús Montoya-Mendoza, Edgar F. Mendoza-Franco
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(American Association for Cancer Research) Among patients with both colorectal cancer and diabetes in Korea, those who had a high adherence to their oral diabetes medication had a significantly reduced risk of overall mortality compared with those with lower adherence.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
This article has been updated to include the latest health services data on Covid-19 as of Sunday, May 31 On the heels of Gov. Doug Ducey announcing the reopening of Arizona schools in the fall and youth sports this summer, the Arizona Department of Health Services has reported two days in a row of record-setting numbers of new Covid-19 cases in the state. On May 30, ADHS reported 790 new cases – the most in a single day since the first case was reported in late January. A day…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Publication date: Available online 30 May 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular Cell ResearchAuthor(s): Deborah Delbue, Bruna S. Mendonça, Marcela C. Robaina, Lauana G.T. Lemos, Pedro I. Lucena, João P.B. Viola, Lídia M. Magalhães, Susanne Crocamo, Caio A.B. Oliveira, Felipe R. Teixeira, Raquel C. Maia, Gabriela Nestal de Moraes
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