Awake ECMO
Extracorporeal membrane oxygenation (ECMO) is used for treatment of severe respiratory or cardiopulmonary failure. Usually these patients are sedated and mechanically ventilated, though at lower tidal volumes to reduce lung injury and permit lung recovery.
The concept of Awake ECMO [1] is to do away with mechanical ventilation permitting the patient to eat, drink, sit up and even possibly walk. They can also participate in physiotherapy. This considered usually in those who are in bridge to transplant situation.
One study documented 6 month survival after lung transplantation as 80% in the awake ECMO group while it was 5...
Source: Cardiophile MD - January 3, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology Source Type: blogs
Medgadget ’s Best Medical Technologies of 2019
Wrapping up this year and looking back on the particularly interesting developments in medical technology, we at Medgadget are impressed and very excited about the future. We’re lucky to cover one of the most innovative fields of research and one that improves and saves lives. Having a constant eye on what’s new in medtech, we present what we believe are the most novel, smart, and medically important technologies we encountered in this passing year. As in years past, a few trends have emerged.
Opiod Overdose Treatment
Opioid addiction, and accompanying overdoses, have become disturbingly common lately. A ...
Source: Medgadget - December 30, 2019 Category: Medical Devices Authors: Medgadget Editors Tags: Exclusive Source Type: blogs
Fight Aging! Newsletter, December 30th 2019
This study presents the effects of berberine (BBR) on the aging process resulting in a promising extension of lifespan in model organisms. BBR extended the replicative lifespan, improved the morphology, and boosted rejuvenation markers of replicative senescence in human fetal lung diploid fibroblasts. BBR also rescued senescent cells with late population doubling (PD). Furthermore, the senescence-associated β-galactosidase (SA-β-gal)-positive cell rates of late PD cells grown in the BBR-containing medium were ~72% lower than those of control cells, and its morphology resembled that of young cells. Mechanistically, BBR im...
Source: Fight Aging! - December 29, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A Digital Stethoscope For Your Kids – The StethoMe Review
Have you ever been confused and uncertain about a basic thing? Like you know you should know it, and it’s definitely a familiar concept, but you’re still not exactly sure?
For instance, when you see the word Worcestershire sauce written on the menu. You may hope it’s not in the name of the dish you choose to order. Why would anyone name a dish after that condiment and is there anyone on this planet, apart from a few Brits, who are confident to pronounce it?
Right. That’s what your average med student feels when trying to auscultate a patient’s heart and lungs for the first time in their lives. It takes quit...
Source: The Medical Futurist - December 19, 2019 Category: Information Technology Authors: szandra Tags: Health Sensors & Trackers Portable Diagnostics AI artificial intelligence stethoscope review children digital health technologies pulmonology Source Type: blogs
Fight Aging! Newsletter, December 16th 2019
This study shows that CA are released from periventricular and subpial regions to the cerebrospinal fluid and are present in the cervical lymph nodes, into which cerebrospinal fluid drains through the meningeal lymphatic system. We also show that CA can be phagocytosed by macrophages. We conclude that CA can act as containers that remove waste products from the brain and may be involved in a mechanism that cleans the brain. Moreover, we postulate that CA may contribute in some autoimmune brain diseases, exporting brain substances that interact with the immune system, and hypothesize that CA may contain brain markers that m...
Source: Fight Aging! - December 15, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Explain yourself, machine. Producing simple text descriptions for AI interpretability
We describe a feature, give a location, and then synthesise a conclusion. For example:
There is an irregular mass with microcalcification in the upper outer quadrant of the breast. Findings are consistent with malignancy.
You don’t need to understand the words I used here, but the point is that the features (irregular mass, microcalcification) are consistent with the diagnosis (breast cancer, malignancy). A doctor reading this report already sees internal consistency, and that reassures them that the report isn’t wrong. An common example of a wrong report could be:
Irregular mass or microcalcification. No ...
Source: The Health Care Blog - December 12, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Artificial Intelligence Health Tech AI Luke Oakden-Rayner machine learning Radiology Source Type: blogs
RSNA 2019 AI Round-Up
Shah Islam
Hugh Harvey
By HUGH HARVEY, MBBS and SHAH ISLAM, MBBS
AI in medical imaging entered the consciousness of radiologists just a few years ago, notably peaking in 2016 when Geoffrey Hinton declared radiologists’ time was up, swiftly followed by the first AI startups booking exhibiting booths at RSNA. Three years on, the sheer number and scale of AI-focussed offerings has gathered significant pace, so much so that this year a decision was made by the RSNA organising committee to move the ever-growing AI showcase to a new space located in the lower level of the North Hall. In some ways it made sense to offe...
Source: The Health Care Blog - December 10, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Artificial Intelligence Health Tech Start-Ups AI Hugh Harvey Radiology RSNA RSNA 2019 RSNA19 Shah Islam Source Type: blogs
Fight Aging! Newsletter, December 9th 2019
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - December 8, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Canon Unveils Aquilion ONE / PRISM Edition Spectral CT Scanner
At the RSNA 2019 conference in Chicago, Canon Medical showed off its brand new Aquilion ONE / PRISM Edition spectral CT scanner, a system that takes advantage of artificial intelligence technologies.
The device relies on Canon’s Advanced intelligent Clear IQ Engine (AiCE) along with its Deep Learning Spectral Reconstruction imaging algorithms to improve capabilities when scanning patients using both conventional and spectral computed tomography.
AiCE is yet to be FDA cleared, but it’s a system that uses deep learning to identify true signals from the noise, resulting in clearer, sharper images. The techn...
Source: Medgadget - December 6, 2019 Category: Medical Devices Authors: Medgadget Editors Tags: Anesthesiology Cardiology Critical Care Diagnostics Emergency Medicine Neurology Ob/Gyn Oncology Radiology Source Type: blogs
Mesodermal Progenitor Cells Enable the Generation of Vascularized Organoids
Researchers have made considerable progress in the construction of small, functional tissue sections called organoids over the past decade, enabled by a combination of better understanding the mechanisms involved in regeneration and embryonic development of tissues, advances in 3-D bioprinting, guidance of cell behavior via appropriate provision of signal molecules, and the generation of environments that mimic an existing tissue environment. Every tissue requires its own specific recipe of signals and environment in order to form a functional organoid, but researchers have demonstrated the manufacture of organoids for liv...
Source: Fight Aging! - December 5, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Artificial Intelligence vs. Tuberculosis, Part 1
By SAURABH JHA, MD
Slumdog TB
No one knows who gave Rahul Roy
tuberculosis. Roy’s charmed life as a successful trader involved traveling in his
Mercedes C class between his apartment on the plush Nepean Sea Road in South
Mumbai and offices in Bombay Stock Exchange. He cared little for Mumbai’s weather.
He seldom rolled down his car windows – his ambient atmosphere, optimized for
his comfort, rarely changed.
Historically TB, or
“consumption” as it was known, was a Bohemian malady; the chronic suffering produced
a rhapsody which produced fine art. TB was fashionable in Victorian Britain, in
part, because c...
Source: The Health Care Blog - December 5, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Artificial Intelligence Health Tech Saurabh Jha TB tuberculosis Source Type: blogs
Fight Aging! Newsletter, November 25th 2019
This study demonstrates for the first time that senescent cells secrete functional LTs, significantly contributing to the LTs pool known to cause or exacerbate idiopathic pulmonary fibrosis.
Against Senolytics
https://www.fightaging.org/archives/2019/11/against-senolytics/
There is no consensus in science that is so strong as to have no heretics. So here we have an interview with a naysayer on the matter of senolytic treatments, who argues that the loss of senescent cells in aged tissues will cause more harm to long-term health than the damage they will do by remaining. To be clear, I think this to be a...
Source: Fight Aging! - November 24, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
House Lawmakers Decide Not to Tackle Respiratory Disease Outbreak: They Decide to Let More Kids Get Sick in Order to Protect a $2.5 Billion Illegal Industry
With more than 2,000 cases of severe respiratory failure--mostly among youth and young adults--and 42 deaths resulting from vaping-associated respiratory illness, one might expect that the House Energy and Commerce Committee would have donesomething to help curtail this outbreak when it voted yesterday on legislation to address the youth vaping crisis.While this week ' s newspaper headlines provided some information about the Committee ' s actions on the proposed youth vaping legislation--for example, that the bill, which bans e-cigarette flavors other than tobacco, passed by a 28-24 vote--those headlines only tell part of...
Source: The Rest of the Story: Tobacco News Analysis and Commentary - November 22, 2019 Category: Addiction Source Type: blogs
Fight Aging! Newsletter, November 11th 2019
In conclusion, high-dose NR induces the onset of WAT dysfunction, which may in part explain the deterioration of metabolic health.
Towards a Rigorous Definition of Cellular Senescence
https://www.fightaging.org/archives/2019/11/towards-a-rigorous-definition-of-cellular-senescence/
The accumulation of lingering senescent cells is a significant cause of aging, disrupting tissue function and generating chronic inflammation throughout the body. Even while the first senolytic drugs capable of selectively destroying these cells already exist, and while a number of biotech companies are working on the producti...
Source: Fight Aging! - November 10, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
3-D Printing of Skin with Embedded Vasculature
Researchers continue to take incremental steps towards the creation of engineered living tissues containing the vascular networks needed to support it. Absent blood vessels, numerous varieties of functional tissue can be generated from cell samples: lung, liver, kidney, and so forth. These organoids are limited in size to a few millimeters, however, the distance the nutrients and oxygen can perfuse. Generating blood vessel networks is a serious technical challenge, and the major obstacle to the production of entire organs for transplantation. Consider that natural capillary networks exhibit a density of hundreds of vessels...
Source: Fight Aging! - November 8, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
