Fight Aging! Newsletter, December 9th 2019

Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/ Contents The Catalytic Antibody Approach to Amyloid Aggregation This Giving Tuesday, Support Rejuvenation Research at the SENS Research Foundation The Prospects for Restoring Neurogenesis in the Aging Brain Mesodermal Progenitor Cells Enable the Generation of Vascularized Organoids Tryptophan Metabolism and Inflammaging More Aggressive Control of Blood Pressure Modestly Extends Life in Older People Potentially Significant Gut Microbiome Changes Occur in Younger Adult Life IL-15 as an Exercise Mimetic that Improves Wound Healing in Old Mice Fibrosis as an Important Contributing Cause of Atrial Fibrillation A Demonstration of Small Molecule Inhibition of Tau Aggregation Discovering New Mechanisms of Action for Metformin On Making Philanthropy in Support of Rejuvenation Research Att...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs

Related Links:

Publication date: Available online 17 January 2020Source: Veterinary ParasitologyAuthor(s): Pengfei Zhao, Yuncan Li, Yanqin Zhou, Junlong Zhao, Rui FangAbstractEimeria tenella, belonging to protozoon, is the causative agent of cecal coccidiosis in chicken and causes enormous impacts for poultry industry. The surface antigens of apicomplexan parasites function as attachment and invasion in host-parasite interaction. Meanwhile, host immune response is triggered as a result of parasitic invasion. Immunogenicity and potency as a vaccinal candidate antigen of E. tenella surface antigen 4 (EtSAG4) have been unknown. Therefore, a...
Source: Veterinary Parasitology - Category: Veterinary Research Source Type: research
Publication date: Available online 17 January 2020Source: Radiation Physics and ChemistryAuthor(s): R. Rajaramakrishna, Y. Ruangtaweep, S. Sattayaporn, P. Kidkhunthod, S. Kothan, J. KaewkhaoAbstractCe3+: Dy3+- codoped calcium zinc gadolinium borate glasses were synthesized by traditional melt quenching technique. These glasses after synthesizing they were characterized through density, molar volume, refractive index, FTIR, absorption spectra, photoluminescence properties, structural studies using XANES/EXAFS and life time profile analysis. XANES spectra of Gd LIII-edge and Dy LIII-edge for 20CaCO3 - 20 ZnO - 10Gd2O3 - 49.5...
Source: Radiation Physics and Chemistry - Category: Physics Source Type: research
Publication date: Available online 18 January 2020Source: Biocatalysis and Agricultural BiotechnologyAuthor(s): Rich Milton R. Dulay, Esperanza C. Cabrera, Sofronio P. Kalaw, Renato G. Reyes, Ching T. HouAbstractLentinus (Family Polyporaceae) is one of the most common fungal groups of wild edible mushrooms found in the Philippines. In our intention to determine the nutritional requirements, this paper highlights the effect of different carbon sources, nitrogen sources, carbon to nitrogen ratios, mineral salts, organic acids, phytohormones, and vitamins on the mycelia growth of Lentinus swartzii, Lentinus strigosus, and Len...
Source: Biocatalysis and Agricultural Biotechnology - Category: Biotechnology Source Type: research
Publication date: Available online 17 January 2020Source: Molecular Aspects of MedicineAuthor(s): Rita Lampignano, Vera Kloten, Thomas Krahn, Thomas SchlangeAbstractLiquid biopsy holds great promise to complement traditional analysis on cancerous tissue during clinical management of cancer: screening of patients, (early) disease diagnosis, prognosis, therapy selection as well as early response to treatment and disease monitoring. Among emerging circulating biomarkers, cell-free miRNA (cfmiRNA) may have potential in detecting lung cancer and following the course of the disease. Furthermore, several studies highlighted the p...
Source: Molecular Aspects of Medicine - Category: Molecular Biology Source Type: research
Publication date: Available online 18 January 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Tomasz Kowalczyk, Michal Ciborowski, Joanna Kisluk, Adam Kretowski, Coral BarbasAbstractPrecision medicine (PM) means the customization of healthcare with decisions and practices adjusted to the individual patient. It includes personalized diagnostics, patients' sub-classification, individual treatment selection and the monitoring of its effectiveness. Currently, in oncology, PM is based on the molecular and cellular features of a tumor, its microenvironment and the patient's genetics and lif...
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - Category: Molecular Biology Source Type: research
Publication date: Available online 18 January 2020Source: Life SciencesAuthor(s): Khalil Hajiasgharzadeh, Mohammad Hossein Somi, Behzad Mansoori, Vahid Khaze Shahgoli, Afshin Derakhshani, Ahad Mokhtarzadeh, Dariush Shanehbandi, Behzad BaradaranAbstractAimsIt has been demonstrated that reduced expression of alpha7 nicotinic acetylcholine receptor (α7nAChR) led to reduced chemotherapeutic drugs resistance in various cancer cells. However, whether small interfering RNA (siRNA) mediated knockdown of α7nAChR can reduce sorafenib (SOR) resistance in HCC cells remains to be determined.Materials and methodsThe effects ...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: Available online 18 January 2020Source: Life SciencesAuthor(s): Zhipei Liu, Yuzhong Jia, Lv Song, Youjia Tian, Peipei Zhang, Peihua Zhang, Zhenzhen Cao, Jihua MaAbstractAimsDetect the antiarrhythmic effect of crotonoside (Cro).Main methodsWe used whole-cell patch-clamp techniques to detect the effects of Cro on action potentials (APs) and transmembrane ion currents in isolated rabbit left ventricular myocytes. We also verified the effect of Cro on ventricular arrhythmias caused by aconitine in vivo.Key findingsCro reduced the maximum depolarization velocity (Vmax) of APs and shortened the action potential...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: Available online 17 January 2020Source: Life SciencesAuthor(s): Bharati Bhattacharjee, Palash Kumar Pal, Aindrila Chattopadhyay, Debasish BandyopadhyayAbstractAimsThe aim of the present study was to evaluate the possible antioxidant role of oleic acid (OA) against Cd-induced injuries in the heart and liver tissues of male Wistar rats.Main methodsRats were treated with either vehicle (control), or OA (10 mg/kg b.w., fed orally), or Cd (0.44 mg/kg b.w., s.c.), or both (OA + Cd) for 15 days. Following completion of the treatment period, biomarkers of organ damage and oxidative stress including ROS,...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: Available online 17 January 2020Source: Process BiochemistryAuthor(s): Siti Marhaida Mustafa, Lee Suan Chua, Hesham Ali El- Enshasy, Fadzilah Adibah Abd Majid, Siti Zulaiha HanapiAbstractLactobacillus casei NRRL-B-1922 was used to ferment whole fruit juice of Punica granatum. P. granatum which is also known as pomegranate could support the growth of L. casei even without nutrient supplementation. This can be seen from the maximum specific growth rate of the strain in shake flasks (0.08 h−1) and stirred tank bioreactor (0.11 h−1). Quercetin-3-glucoside was detected as the most abu...
Source: Process Biochemistry - Category: Biochemistry Source Type: research
Publication date: Available online 18 January 2020Source: Biochimica et Biophysica Acta (BBA) - BiomembranesAuthor(s): Miranda L. Schmidt, James H. DavisAbstractLipid bilayers form the basis of cell membranes and the phase behaviour of the membrane has been linked to proper cell function. Model membranes composed of relatively simple mixtures of phospholipids and cholesterol can already exhibit complex phase behaviour. Specifically, liquid ordered–liquid disordered fluid phase coexistence occurs in mixtures which contain one saturated long chain phospholipid and one unsaturated long chain phospholipid and cholesterol...
Source: Biochimica et Biophysica Acta (BBA) Biomembranes - Category: Biochemistry Source Type: research
More News: Allergy & Immunology | Alzheimer's | Amyloidosis | Arrhythmia | Atrial Fibrillation | Autoimmune Disease | Biochemistry | Biotechnology | Brain | Brain Cancers | Calcium | Cancer | Cancer & Oncology | Cancer in Adolescents | Cancer in Young Adults | Cancer Vaccines | Cardiac Arrhythmia | Cardiology | Cardiovascular | Carpal Tunnel Syndrome | Chemistry | Child Development | Childhood Cancer | Cholesterol | Chronic Kidney Disease | Clinical Trials | Dementia | Diabetes | Diabetes Mellitus | Diabetes Type 1 | Diabetes Type 2 | Diets | Disability | Eating Disorders & Weight Management | Education | Endocrinology | Environmental Health | Epidemiology | Epithelial Cancer | Fortamet | Gastric (Stomach) Cancer | Gastroenterology | Gastroschisis Repair | Genetics | Geriatrics | Germany Health | Heart | Heart Attack | Heart Disease | Heart Failure | Heart Transplant | High Fat | Hypertension | Information Technology | Insulin | International Medicine & Public Health | Ischemic Stroke | Kidney Transplant | Kidney Transplantation | Laboratory Medicine | Learning | Lessons | Liver | Liver Transplant | Lumbar Spinal Stenosis | Lung Transplant | Medical Ethics | Metformin | Mitochondria | Mitochondrial Disease | Neurology | Neuroscience | Nutrition | Obesity | Pancreas | Pancreatic Cancer | Pathology | Psychology | Research | Science | Skin | Sports Medicine | Stem Cell Therapy | Stem Cells | Stroke | Study | Toxicology | Transplant Surgery | Transplants | Universities & Medical Training | Urology & Nephrology | Vaccines | Veterinary Vaccinations | WHO