Fight Aging! Newsletter, December 9th 2019

Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/ Contents The Catalytic Antibody Approach to Amyloid Aggregation This Giving Tuesday, Support Rejuvenation Research at the SENS Research Foundation The Prospects for Restoring Neurogenesis in the Aging Brain Mesodermal Progenitor Cells Enable the Generation of Vascularized Organoids Tryptophan Metabolism and Inflammaging More Aggressive Control of Blood Pressure Modestly Extends Life in Older People Potentially Significant Gut Microbiome Changes Occur in Younger Adult Life IL-15 as an Exercise Mimetic that Improves Wound Healing in Old Mice Fibrosis as an Important Contributing Cause of Atrial Fibrillation A Demonstration of Small Molecule Inhibition of Tau Aggregation Discovering New Mechanisms of Action for Metformin On Making Philanthropy in Support of Rejuvenation Research Att...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs

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Publication date: January 2021Source: Language Sciences, Volume 83Author(s): Hilde De Vaere, Ludovic De Cuypere, Klaas Willems
Source: Language Sciences - Category: Speech-Language Pathology Source Type: research
Background and Purpose: Accidents, both intentional and unintentional, are one of the leading causes of death and disability for children around the world and impose a heavy financial burden on the health care system of societies. The aim of the present st...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Road accidents are one of the causes of disability, injury and death. As per the latest road accident data released by the Ministry of Road Transport&Highways (MoRTH), the total number of accidents increased by 2.5 percent from 4,89,400 in 2014 to 5,01,4...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news
This study aims to address t...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
In this study, microarray analysis was used for gene expression profiling in rat prostate tissue after exposure to EDCs and sex hormones over multiple time points (prepubertal through adulthood). We used dorsolateral prostate tissues from Sprague-Dawley rats (male offspring) and postnatally administered estradiol benzoate (EB) on postnatal days (PNDs) 1, 3, and 5, followed by treatment with additional hormones [estradiol (E) and testosterone (T)] on PNDs 90-200, as described by Ho et al. Microarray analysis was performed for gene expression profiling in the dorsolateral prostate, and the results were validated via qRT-PCR....
Source: Journal of Toxicological Sciences - Category: Toxicology Tags: J Toxicol Sci Source Type: research
Authors: Zhao HW, Liu H, Liu LY, Liu Z, Dong XS Abstract Paraquat (PQ) as a non-selective heterocyclic herbicide, has been applied worldwide for over a few decades. But PQ is very harmful to humans and rodents. The lung is the main target organ of PQ poisoning. It is an important event that lung epithelial cells are injured during PQ-induced acute lung injury and pulmonary fibrosis. As a regulator of mRNA expression, microRNA (miRNA) may play an important role in the progress. Our study was to investigate the mechanisms of PQ-induced injury of pulmonary epithelial cells through analyzing the profiling of miRNAs and...
Source: Journal of Toxicological Sciences - Category: Toxicology Tags: J Toxicol Sci Source Type: research
Source: Risk Management and Healthcare Policy - Category: Health Management Tags: Risk Management and Healthcare Policy Source Type: research
CONCLUSION: A significant proportion of patients with LDL-C≥250 mg/dL were not taking lipid-lowering drugs. Similar with many other studies, diagnosis and treatment rates of FH patients were very low in our study. Further national studies are required to increase awareness of the disease in both physicians and patients. PMID: 32744105 [PubMed - as supplied by publisher]
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
Source: Patient Preference and Adherence - Category: International Medicine & Public Health Tags: Patient Preference and Adherence Source Type: research
CONCLUSIONS: Type 1 diabetes in both genders and all ages was associated with significantly elevated SMRs for all-cause and mostly for diabetes per se and renal disease. PMID: 32741854 [PubMed - as supplied by publisher]
Source: Journal of Epidemiology - Category: Epidemiology Tags: J Epidemiol Source Type: research
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