EchoNous KOSMOS 3-in-1 Ultrasound, Electronic Stethoscope, and ECG Helps with COVID-19
EchoNous, a developer of novel ultrasounds, has found a way to leverage multiple critical clinical technologies within a single device. The result is KOSMOS, a handheld 3-in-1 device consisting of an ultrasound, electronic stethoscope, and an ECG, all linked via artificial technology. When COVID-19 was hitting NYC earlier this year, EchoNous was able to use KOSMOS to help diagnose COVID patients and to inform on treatment strategies. We had a lovely chat with Dr. Richard Hoppmann, a key member of EchoNous, Clinical Professor of Internal Medicine at the University of South Carolina, and the Director of the Ultrasou...
Source: Medgadget - September 21, 2020 Category: Medical Devices Authors: Alice Ferng Tags: Cardiology Critical Care Diagnostics Exclusive Informatics Medicine Public Health Source Type: blogs

How Did We Screw A Pandemic Up So Bad?
We’re still in the thick of things when it comes to the coronavirus pandemic. Countries are bracing themselves for a second wave. Scientists are still racing to find a vaccine. We wrote a whole e-book with resources to help you in the fight against COVID-19 while indoors. And we even had to tackle the conspiracy theories that captured way too many people’s imagination. Thankfully, those conspiracy theories represented the thoughts and actions of an irrational minority. But even the slow and misguided actions of the rational majority further escalated and worsened the crisis. In our tech-aided, always-connect...
Source: The Medical Futurist - September 9, 2020 Category: Information Technology Authors: Prans Tags: Artificial Intelligence Future of Pharma Healthcare Policy Video china leadership Fauci Trump pandemic second wave covid-19 Bolsonaro U.S. vaccine new normal Source Type: blogs

Fight Aging! Newsletter, September 7th 2020
In conclusion, using a large cohort with rich health and DNA methylation data, we provide the first comparison of six major epigenetic measures of biological ageing with respect to their associations with leading causes of mortality and disease burden. DNAm GrimAge outperformed the other measures in its associations with disease data and associated clinical traits. This may suggest that predicting mortality, rather than age or homeostatic characteristics, may be more informative for common disease prediction. Thus, proteomic-based methods (as utilised by DNAm GrimAge) using large, physiologically diverse protein sets for p...
Source: Fight Aging! - September 6, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, August 31st 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - August 30, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Targeted Therapeutics for Critical Illnesses: Interview with Jason Springs, CEO of Endpoint Health
With the COVID-19 pandemic, critical illnesses, such as Acute Respiratory Distress Syndrome and sepsis are coming into the spotlight. Despite their severity and risk for patients, critical illnesses remain understudied and lack the number of treatment options of many other diseases with a similar level of mortality and morbidity. Part of the challenge lies in the time sensitivity of such conditions, whereby clinicians have little time to make treatment decisions and typically can’t tailor the treatment for individual patient needs. The quest to develop more tailored treatments for such illnesses is what drives End...
Source: Medgadget - August 13, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Critical Care Exclusive Informatics Medicine Source Type: blogs

AI System Decides When to Help Diagnose X-Rays
Artificial intelligence is playing an ever larger role in modern clinical care. For example, there are already imaging processing systems that are able to automatically spot polyps during colonoscopies and help analyze head CT scans for hemorrhage and mass effect. A universal issue with such systems is that they do not take into account how experienced, busy, or in need of actual help a given clinician is. A team of MIT researchers has now developed a machine learning system that can adjust how it makes clinically relevant decisions, whether to let an expert decide something or to do so itself, and to do so while taking in...
Source: Medgadget - August 11, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Informatics Radiology Source Type: blogs

Fight Aging! Newsletter, July 13th 2020
In conclusion, sitting for prolonged periods of time without interruption is unfavorably associated with DBP and HDL cholesterol. Exercise Slows Inappropriate Growth of Blood Vessels in a Mouse Model of Macular Degeneration https://www.fightaging.org/archives/2020/07/exercise-slows-inappropriate-growth-of-blood-vessels-in-a-mouse-model-of-macular-degeneration/ Excessive growth of blood vessels beneath the retina is a proximate cause of blindness in conditions such as macular degeneration. Researchers here provide evidence for physical activity to be influential in the pace at which this process of tissue...
Source: Fight Aging! - July 12, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Digital Health Ventures That Flew Too Close To The Sun
1.5 billion: that’s the number, in dollars, Forbes put for Proteus’ valuation last year. Dubbed as a healthcare unicorn, the startup even raised over $500 million in venture capital. It made headlines for developing the first-ever FDA-approved digital pill, one equipped with an ingestible and trackable sensor to monitor treatment compliance.  Researchers even proved the technology’s worth. In 2019, an independent study investigated the Proteus’ digital pill. They found it to be accurate, and even improved adherence of tuberculosis patients using oral pills equipped with Proteus’ s...
Source: The Medical Futurist - July 7, 2020 Category: Information Technology Authors: Prans Tags: Artificial Intelligence Future of Medicine Future of Pharma Genomics AI cancer IBM google deepmind theranos Watson fail digital pill proteus deus ex machina tech giants finances otsuka Nightingale Source Type: blogs

Robotic Transcranial Doppler for Stroke Detection and Risk Assessment in COVID: Interview with Diane Bryant, Neural Analytics
Emerging evidence suggests that COVID-19 patients are at a higher risk of stroke and promptly diagnosing and treating such patients is a priority in hospitals across the world. Moreover, identifying which COVID-19 patients are at increased risk of developing a stroke is also important, and may help with preemptive treatment and monitoring. The Lucid Robotic System, developed by LA-based Neural Analytics, is a transcranial doppler system that allows clinicians to identify clots and changes in blood flow in the brain in real time, without needing a specialized technician. The device is robotically assisted and automat...
Source: Medgadget - July 6, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Critical Care Emergency Medicine Exclusive Neurology Neurosurgery Source Type: blogs

Fight Aging! Newsletter, July 6th 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - July 5, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Virtual Care Platform for Respiratory Illness: Interview with Stacie Ruth, CEO of AireHealth
AireHealth, a medtech company based in Orlando, Florida, currently offers a portable nebulizer and companion app for respiratory patients aged two and over. The small nebulizer can be charged using a micro USB charger and then placed in a bag or pocket for easy transport and use on the move. The companion app is geared toward increasing patient engagement and medication adherence, which is important in maximizing therapeutic outcomes among chronic respiratory patients. Recently, AireHealth announced a merger with BreathResearch, a respiratory healthcare company based in Silicon Valley that specializes in detection and m...
Source: Medgadget - July 2, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Informatics Medicine Telemedicine AireHealth Source Type: blogs

Fight Aging! Newsletter, June 29th 2020
In conclusion, metabolomics is a promising approach for the assessment of biological age and appears complementary to established epigenetic clocks. Sedentary Behavior Raises the Risk of Cancer Mortality https://www.fightaging.org/archives/2020/06/sedentary-behavior-raises-the-risk-of-cancer-mortality/ Living a sedentary lifestyle is known to be harmful to long term health, raising the risk of age-related disease and mortality. Researchers here show that a sedentary life specifically increases cancer mortality, and does so independently of other factors. This is one of many, many reasons to maintain a re...
Source: Fight Aging! - June 28, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Autoimmune lung disease: Early recognition and treatment helps
A man who was diagnosed with rheumatoid arthritis (RA) five years ago sees his rheumatologist for a follow-up visit. Fortunately, his arthritis is well controlled through medication. He can walk and do all his daily activities without pain. But over the past six months, he’s been feeling short of breath when climbing stairs. He has an annoying dry cough, too. COVID-19? That’s ruled out quickly. But a CT scan of his chest reveals early fibrosis (scarring) of the lungs, most likely related to rheumatoid arthritis. “I can finally walk normally, and now I can’t breathe when I walk!” says the frust...
Source: Harvard Health Blog - June 24, 2020 Category: Consumer Health News Authors: Paul F. Dellaripa, MD Tags: Arthritis Autoimmune diseases Health Inflammation Lung disease Source Type: blogs

Fight Aging! Newsletter, June 15th 2020
In this study, we used markers to monitor the formation of SGs in Caenorhabditis elegans. We found that, in addition to acute heat stress, SG formation could also be triggered by dietary changes, such as starvation and dietary restriction (DR). We found that HSF-1 is required for the SG formation in response to acute heat shock and starvation but not DR, whereas the AMPK-eEF2K signaling is required for starvation and DR-induced SG formation but not heat shock. Moreover, our data suggest that this AMPK-eEF2K pathway-mediated SG formation is required for lifespan extension by DR, but dispensable for the longevity by reduced ...
Source: Fight Aging! - June 14, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Network Medicine in the Fight Against COVID-19
COVID-19 forced stakeholders in the healthcare landscape to adopt a new perspective in this sphere. Telemedicine rose to fame as a ready-made solution; artificial intelligence’s contribution became more apparent from early outbreak predictions to resource management; and digital health technologies lent a helping hand early on. Another promising area joining the fight is network medicine, a branch of network science. The latter field studies the interaction between actors within a network. Such analyses are applicable to virtually any sector, from the world wide web through social networks to how molecules interac...
Source: The Medical Futurist - May 21, 2020 Category: Information Technology Authors: Prans Tags: Network medicine Artificial Intelligence Biotechnology Telemedicine & Smartphones AI MIT coronavirus covid covid19 vaccine research pandemic network science Albert-László Barabási Source Type: blogs

Fight Aging! Newsletter, May 18th 2020
This study provides direct evidence for the contribution of gut microbiota to the cognitive decline during normal aging and suggests that restoring microbiota homeostasis in the elderly may improve cognitive function. On Nutraceutical Senolytics https://www.fightaging.org/archives/2020/05/on-nutraceutical-senolytics/ Nutraceuticals are compounds derived from foods, usually plants. In principle one can find useful therapies in the natural world, taking the approach of identifying interesting molecules and refining them to a greater potency than naturally occurs in order to produce a usefully large therape...
Source: Fight Aging! - May 17, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, May 11th 2020
In this study, we found that older nematodes have higher ROS levels. Interestingly, after hydrogen treatment, the ROS levels were significantly decreased, and hydrogen could significantly extend the lifespans of the N2, sod-3 and sod-5 mutant strains, by approximately 22.7%, 9.5%, and 8.7%, respectively. In addition, aging is regulated by a variety of pathways, such as the insulin signaling pathway, the rapamycin target signaling pathway, and the caloric restriction pathway. However, our results showed that the lifespans of the daf-2 and daf-16 strains, in which these pathways are upregulated, were not affected afte...
Source: Fight Aging! - May 10, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Top 5 Practical Digital Health Technologies in the Fight Against COVID-19: An Infographic
We reported on how digital health came to the spotlight early on. As we learn more about the disease, we see digital health technologies increasingly getting adopted in this context. We created an infographic to summarize all the digital health tech efforts against this pandemic.  This will help caregivers and policymakers understand how we can rely on technologies in the fight against the novel coronavirus; and which sectors and phases of healthcare are aided by digital health. In our infographic, listed on the Y-axis are the technologies making a significant impact in the fight against the pandemic. Indicated ...
Source: The Medical Futurist - May 7, 2020 Category: Information Technology Authors: Prans Tags: Future of Medicine Telemedicine & Smartphones Virtual Reality digital health infographics covid covid19 Source Type: blogs

Fight Aging! Newsletter, May 4th 2020
The objective is to start treating chronic diseases from the root and not the symptoms of the disease. As we are starting to enroll patients in "senolytics-clinical trials," it will be imperative to assess if senolysis efficiently targets the primary cause of disease or if it works best in combination with other drugs. Additional basic science research is required to address the fundamental role of senescent cells, especially in the established contexts of disease. Notes on Self-Experimentation with Sex Steroid Ablation for Regrowth of the Thymus https://www.fightaging.org/archives/2020/04/notes-on-se...
Source: Fight Aging! - May 3, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

COVID-19: Physicians in Shackles
By ANISH KOKA, MD A number of politically tinged narratives have divided physicians during the pandemic. It would be unfortunate if politics obscured the major problem brought into stark relief by the pandemic: a system that marginalizes physicians and strips them of agency. In practices big and small, hospital-employed or private practice, nursing homes or hospitals, there are serious issues raising their heads for doctors and their patients. No masks for you When I walked into my office Thursday, March 12th, I assembled the office staff for the first time to talk about COVID.  The prior weekend had been...
Source: The Health Care Blog - May 2, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Medical Practice Physicians Anish Koka medical autonomy Pandemic Source Type: blogs

Adding Voice to Respiratory and Cardiovascular Disease Diagnosis: Interview with Prof. Elad Maor
The field of telehealth is growing thanks to the steady growth in supportive technology and the need for remote monitoring, assessment, diagnosis, and testing. Voice is unique to every individual due to people’s anatomical differences, which makes for a powerful tool when working remotely. Vocalis Health is a company that uses machine learning and artificial intelligence to identify biomarkers in voice recordings. The company’s technology has been successfully used to identify mortality and hospitalization among heart failure patients. Vocalis is now adapting their technology to understand the associati...
Source: Medgadget - April 29, 2020 Category: Medical Devices Authors: Rukmani Sridharan Tags: Cardiology Diagnostics Exclusive Public Health Source Type: blogs

Beware the COVID-tech Cowboys
This article originally appeared on the Hardian Health blog here. The post Beware the COVID-tech Cowboys appeared first on The Health Care Blog. (Source: The Health Care Blog)
Source: The Health Care Blog - April 22, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Uncategorized Source Type: blogs

Left ventricular assist device (LVAD)
Left ventricular assist device is used to support the failing left ventricle when it is refractory to guideline directed medical therapy. It can be either a bridge to cardiac transplantation or a destination therapy. In general, cardiac transplantation offers better long term surival compared to LVAD according data available from devices except the most recent. As per the The Registry of the International Society for Heart and Lung Transplantation: Thirty-fourth Adult Heart Transplantation Report-2017 [1], there were 126,753 pediatric and adult heart transplants between 1982 and June 2015. Median survival was 10.7 years i...
Source: Cardiophile MD - April 16, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiac Surgery LVAD Source Type: blogs

The (Sober) State of Artificial Intelligence in the Fight Against COVID-19
If you ask us at The Medical Futurist about the importance of artificial intelligence in healthcare, we will have a lot to talk about. We’ve seen how it could solve alarm fatigue in hospitals. We’ve analyzed the unusual associations the technology discovered in medicine. We believe it will usher the real era of the Art of Medicine. Dr. Meskó even embarked on a journey to better understand the language of A.I. So of course, with the COVID-19 pandemic, we had to explore the contribution of A.I. in this public health crisis. We came across promising endeavours involving such algorithms from mining for in...
Source: The Medical Futurist - April 14, 2020 Category: Information Technology Authors: Prans Tags: Artificial Intelligence Future of Medicine digital health coronavirus covid covid19 Source Type: blogs

Fight Aging! Newsletter, April 13th 2020
This study is par for the course, looking at Japanese Olympic participants. Interestingly, it hints at the upper end of the dose-response curve for physical activity, in that a longer career as a professional athlete may be detrimental in comparison to lesser degrees of exercise and training. From this large, retrospective cohort study targeting 3546 Japanese Olympic athletes, we observed significant lower mortality among Olympians compared with the Japanese general population. The overall standardised mortality ratio (SMR) was 0.29. The results were consistent with previous studies conducted in other non-Asian co...
Source: Fight Aging! - April 12, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

‘Sophie’s Choice’ in the time of coronavirus: Deciding who gets the ventilator
Three otherwise healthy patients go to the emergency department with severe acute respiratory failure. Only one ventilator, required to sustain life until the worst of the coronavirus infection has passed, is available. Who gets the vent? That’s what “A Framework for Rationing Ventilators and Critical Care Beds During the COVID-19 Pandemic,” a Viewpoint just published in the Journal of the American Medical Association (JAMA), addresses. Douglas White, MD, MAS, Endowed Chair for Ethics in Critical Care Medicine at the University of Pittsburgh School of Medicine ...
Source: blog.bioethics.net - April 6, 2020 Category: Medical Ethics Authors: Bioethics Today Tags: Health Care Author: Lewis syndicated Source Type: blogs

Fight Aging! Newsletter, April 6th 2020
This study delves into the mechanisms by which a short period of fasting can accelerate wound healing. Fasting triggers many of the same cellular stress responses, such as upregulated autophagy, as occur during the practice of calorie restriction. It isn't exactly the same, however, so it is always worth asking whether any specific biochemistry observed in either case does in fact occur in both situations. In particular, the period of refeeding following fasting appears to have beneficial effects that are distinct from those that occur while food is restricted. Multiple forms of therapeutic fasting have been repor...
Source: Fight Aging! - April 5, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Getting Ready to Confront the Unthinkable
by Arthur Caplan, Ph.D. Rationing  has always been present in the American health care system.  Some poor individuals have not had access to certain treatments due to a lack of health insurance or hospitals not willing to accept them if they cannot pay.  And those in the transplant field have had to contend for decades with a shortage of organs forcing organized rationing in which many more die than benefit from access to a life-saving liver, heart or lung.  Emergency medicine personnel in big hospitals drill frequently on how to triage after a terrorist attack, a huge chemical plant explosion, an earth...
Source: blog.bioethics.net - March 31, 2020 Category: Medical Ethics Authors: Arthur Caplan Tags: Ethics Featured Posts Public Health #diaryofaplagueyear COVID-19 rationing Rationing/ Resource Allocation Source Type: blogs

Can AI diagnose COVID-19 on CT scans? Can humans?
Vidur Mahajan Vasanth Venugopal By VASANTH VENUGOPAL MD and VIDUR MAHAJAN MBBS, MBA What can Artificial Intelligence (AI) do? AI can, simply put, do two things – one, it can do what humans can do. These are tasks like looking at CCTV cameras, detecting faces of people, or in this case, read CT scans and identify ‘findings’ of pneumonia that radiologists can otherwise also find – just that this happens automatically and fast. Two, AI can do things that humans can’t do – like telling you the exact time it would take you to go from point A to point B (i.e. Google maps), or like ...
Source: The Health Care Blog - March 23, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Artificial Intelligence COVID-19 Health Tech AI coronavirus CT scans Pandemic Radiology Vasanth Venugopal Vidur Mahajan Source Type: blogs

Fight Aging! Newsletter, March 23rd 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - March 22, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

I ’ve been on a ventilator before, so I’d like to sit this pandemic out
I have bled out during emergency surgery and been revived by the expert trauma and transplant team who raced into my operating room. I have had liter upon liter of donated blood transfused into my grey lifeless body. I survived months on a ventilator in an intensive care unit. I have had my lungs fill […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 19, 2020 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/lisa-goodman-helfand" rel="tag" > Lisa Goodman-Helfand < /a > < /span > Tags: Conditions COVID-19 coronavirus Infectious Disease Source Type: blogs

Digital Twins and the Promise of Personalized Medicine
Can you guess the percentage of patients with Alzheimer’s on whom medication is ineffective? What about those with arthritis? Or cardiac arrhythmia? In fact, you don’t have to guess as the US Food and Drug Administration (FDA) already has the answers: 70%, 50% and 40% respectively. The percentage of patients for whom medications are ineffective range from 38-75% for varying conditions from depression to osteoporosis.  The main cause is because of the very genetic makeup of every individual. The latter is so different and their interaction so unique that therapies for the “average patient” mi...
Source: The Medical Futurist - March 19, 2020 Category: Information Technology Authors: Prans Tags: Future of Medicine Personalized Medicine digital health technology healthcare data digital twin technology design Source Type: blogs

Why Peak Viral Load makes temperature screening alone insufficient for COVID-19
By TONY ESTRELLA And how South Korea and Taiwan’s approach to diagnosis and tracking is leading to positive results By now, the sight of people wearing surgical masks, flinching at the sights and sounds of someone coughing or sneezing, governments restricting large gatherings, and sports leagues suspending or cancelling matches is familiar across the world. Even though this newest coronavirus we now call COVID-19 is not the deadliest disease as measured by daily deaths, the concern over the outbreak is forcing urgent actions. Daily deaths from COVID-19 compared to other diseases. Source: informationisbeau...
Source: The Health Care Blog - March 16, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy Source Type: blogs

Fight Aging! Newsletter, March 9th 2020
In this study, we intravenously administrated the young mitochondria into aged mice to evaluate whether energy production increase in aged tissues or age-related behaviors improved after the mitochondrial transplantation. The results showed that heterozygous mitochondrial DNA of both aged and young mouse coexisted in tissues of aged mice after mitochondrial administration, and meanwhile, ATP content in tissues increased while reactive oxygen species (ROS) level reduced. Besides, the mitotherapy significantly improved cognitive and motor performance of aged mice. Our study, at the first report in aged animals, not only prov...
Source: Fight Aging! - March 8, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The 7 Must-Haves For The Doctor Of the 21st Century
While Doctor Who is embracing change, casting two female leads in a row as the titular character following the series’ tradition of having male leads, real life doctors should take some cues from the fictional doctor when it comes to change. For ages, physicians have been relying on traditional methods when it comes to consulting patients and follow a rote template akin to the following: patients see the doctor who auscultates them with manual techniques, without forgetting the stethoscope, and will prescribe them some medication or lifestyle change. In specific cases, they will recommend a more detailed diagnostic m...
Source: The Medical Futurist - March 5, 2020 Category: Information Technology Authors: Prans Tags: Future of Medicine Portable Diagnostics digital health smartphone healthcare systems digital stethoscope Source Type: blogs

Fight Aging! Newsletter, February 24th 2020
In conclusion, taller body height at the entry to adulthood, supposed to be a marker of early-life environment, is associated with lower risk of dementia diagnosis later in life. The association persisted when adjusted for educational level and intelligence test scores in young adulthood, suggesting that height is not just acting as an indicator of cognitive reserve. A Comparison of Biological Age Measurement Approaches https://www.fightaging.org/archives/2020/02/a-comparison-of-biological-age-measurement-approaches/ Researchers here assess the performance of a range of approaches to measuring biological...
Source: Fight Aging! - February 23, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, February 17th 2020
Discussion of the Evolutionary Genetics of Aging Thymic Involution Contributes to Immunosenescence and Inflammaging The Potential for Exosome Therapies to Treat Sarcopenia Correlations of Mitochondrial DNA Copy Number and Epigenetic Age Measures Evidence for PASK Deficiency to Reduce the Impact of Aging in Mice The Aging Retina, a Mirror of the Aging Brain Evidence for Loss of Capillary Density to be Important in Heart Disease Aspects of Immune System Aging Proceed More Rapidly in Men Deacetylation of the NLRP3 Inflammasome as a Way to Control Chronic Inflammation Transplantation of Senescent Cells is an ...
Source: Fight Aging! - February 16, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Notes on the 2020 Longevity Therapeutics Conference in San Francisco
I recently attended the 2020 Longevity Therapeutics conference in San Francisco. I presented on the work ongoing at Repair Biotechnologies, but as is usually the case the more important parts of the visit took place outside the bounds of the conference proper. Longevity Therapeutics is one of the four or five core conferences for the longevity industry, at which you'll meet many of the early participants - a mix of scientists, entrepreneurs, and investors, and patient advocates. As such, most of the conference goers have already seen my updates, or are otherwise aware of the Repair Biotechnologies programs aimed at thymic ...
Source: Fight Aging! - February 10, 2020 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs

New Membranes to Make Extracorporeal Oxygenation More Effective
When lungs fail because of acute respiratory distress and cannot be used to deliver oxygen to patients via conventional ventilation, extracorporeal membrane oxygenation (ECMO) has to be employed. ECMOs remove carbon dioxide from whole blood and replace it with oxygen thanks to a membrane oxygenator. While such artificial lungs are effective for short periods of time for many patients, for others this procedure is just too difficult. The gas exchange process performed by ECMOs is just too slow compared with what healthy lungs can achieve. Now, researchers at Fraunhofer Institute for Applied Polymer Research (IAP) in Germ...
Source: Medgadget - February 3, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Anesthesiology Critical Care Emergency Medicine Materials Thoracic Surgery Source Type: blogs

Fight Aging! Newsletter, February 3rd 2020
In conclusion, this study suggests that epigenetic age acceleration is significantly associated with lung function in women older than 50 years. We hypothesised that this could be due to menopause. However, we have observed that menopause has minimal effect and therefore there is possibility of other unknown physiological factors at older age in females mediating the epigenetic age acceleration effect on lung function. While, it is still unknown what exactly epigenetic aging from DNA methylation measures, this study suggests it can be utilised as one of the important factors to assess women's lung health in old age. DNA me...
Source: Fight Aging! - February 2, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, January 27th 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - January 26, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Artificial Intelligence vs. Tuberculosis – Part 2
By SAURABH JHA, MD Clever Hans Preetham Srinivas, the head of the chest radiograph project in Qure.ai, summoned Bhargava Reddy, Manoj Tadepalli, and Tarun Raj to the meeting room. “Get ready for an all-nighter, boys,” said Preetham. Qure’s scientists began investigating the algorithm’s mysteriously high performance on chest radiographs from a new hospital. To recap, the algorithm had an area under the receiver operating characteristic curve (AUC) of 1 – that’s 100 % on multiple-choice question test. “Someone leaked the paper to AI,” laughed Manoj. “I...
Source: The Health Care Blog - January 25, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Artificial Intelligence Health Tech Health Technology @roguerad AI Saurabh Jha TB tuberculosis Source Type: blogs

Top Artificial Intelligence Companies in Healthcare to Keep an Eye On
The field of medical AI is buzzing. More and more companies set the purpose to disrupt healthcare with the help of artificial intelligence. Given how fast these companies come and go, it can prove to be hard to stay up-to-date with the most promising ones. Here, I collected the biggest names currently on the market ranging from start-ups to tech giants to keep an eye on in the future. To further help you keep up with what A.I. brings to medicine, The Medical Futurist team made an easy-to-digest e-book about just that. I highly encourage you to read it and would love to hear about your thoughts! Artificial Intelligence has ...
Source: The Medical Futurist - January 21, 2020 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence Healthcare Design AI digital health genetics Innovation Personalized medicine pharma GC1 big data drug development healthcare companies medical imaging Source Type: blogs

Fight Aging! Newsletter, January 20th 2020
This study provides strong evidence that following a healthy lifestyle can substantially extend the years a person lives disease-free." Commentary on Recent Evidence for Cognitive Decline to Precede Amyloid Aggregation in Alzheimer's Disease https://www.fightaging.org/archives/2020/01/commentary-on-recent-evidence-for-cognitive-decline-to-precede-amyloid-aggregation-in-alzheimers-disease/ I can't say that I think the data presented in the research noted here merits quite the degree of the attention that it has been given in the popular science press. It is interesting, but not compelling if its role...
Source: Fight Aging! - January 19, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, January 13th 2020
In this study, we investigated the link between AF and senescence markers through the assessment of protein expression in the tissue lysates of human appendages from patients in AF, including paroxysmal (PAF) or permanent AF (PmAF), and in sinus rhythm (SR). The major findings of the study indicated that the progression of AF is strongly related to the human atrial senescence burden as determined by p53 and p16 expression. The stepwise increase of senescence (p53, p16), prothrombotic (TF), and proremodeling (MMP-9) markers observed in the right atrial appendages of patients in SR, PAF, and PmAF points toward multiple inter...
Source: Fight Aging! - January 12, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Easy-to-Remove Superhydrophobic Bandage Speeds Clotting of Wounds
Researchers at ETH Zurich and National University of Singapore have developed a new type of bandage that does not stick to the wound while helping blood to clot beneath it. This is the first time scientists have combined both properties in one material and the capability allows the bandage to promote healing and be easily removed or changed as necessary. While their quest initially began with developing a material for coating heart and lung assist devices and artificial hearts, these researchers came upon an unexpected discovery. They developed and tried various superhydrophobic materials and one of them repelled blood...
Source: Medgadget - January 10, 2020 Category: Medical Devices Authors: Siavash Parkhideh Tags: Materials Medicine Plastic Surgery Source Type: blogs

Awake ECMO
Extracorporeal membrane oxygenation (ECMO) is used for treatment of severe respiratory or cardiopulmonary failure. Usually these patients are sedated and mechanically ventilated, though at lower tidal volumes to reduce lung injury and permit lung recovery. The concept of Awake ECMO [1] is to do away with mechanical ventilation permitting the patient to eat, drink, sit up and even possibly walk. They can also participate in physiotherapy. This considered usually in those who are in bridge to transplant situation. One study documented 6 month survival after lung transplantation as 80% in the awake ECMO group while it w...
Source: Cardiophile MD - January 3, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology Source Type: blogs

Medgadget ’s Best Medical Technologies of 2019
Wrapping up this year and looking back on the particularly interesting developments in medical technology, we at Medgadget are impressed and very excited about the future. We’re lucky to cover one of the most innovative fields of research and one that improves and saves lives. Having a constant eye on what’s new in medtech, we present what we believe are the most novel, smart, and medically important technologies we encountered in this passing year. As in years past, a few trends have emerged. Opiod Overdose Treatment Opioid addiction, and accompanying overdoses, have become disturbingly common lately. A ...
Source: Medgadget - December 30, 2019 Category: Medical Devices Authors: Medgadget Editors Tags: Exclusive Source Type: blogs

Fight Aging! Newsletter, December 30th 2019
This study presents the effects of berberine (BBR) on the aging process resulting in a promising extension of lifespan in model organisms. BBR extended the replicative lifespan, improved the morphology, and boosted rejuvenation markers of replicative senescence in human fetal lung diploid fibroblasts. BBR also rescued senescent cells with late population doubling (PD). Furthermore, the senescence-associated β-galactosidase (SA-β-gal)-positive cell rates of late PD cells grown in the BBR-containing medium were ~72% lower than those of control cells, and its morphology resembled that of young cells. Mechanistically...
Source: Fight Aging! - December 29, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Digital Stethoscope For Your Kids – The StethoMe Review
Have you ever been confused and uncertain about a basic thing? Like you know you should know it, and it’s definitely a familiar concept, but you’re still not exactly sure? For instance, when you see the word Worcestershire sauce written on the menu. You may hope it’s not in the name of the dish you choose to order. Why would anyone name a dish after that condiment and is there anyone on this planet, apart from a few Brits, who are confident to pronounce it? Right. That’s what your average med student feels when trying to auscultate a patient’s heart and lungs for the first time in their ...
Source: The Medical Futurist - December 19, 2019 Category: Information Technology Authors: szandra Tags: Health Sensors & Trackers Portable Diagnostics AI artificial intelligence stethoscope review children digital health technologies pulmonology Source Type: blogs