Smart Stethoscope Helps Monitor and Diagnose Respiratory Conditions: Interview with Helena Binetskaya, CEO of Healthy Networks
LungPass, an AI-powered Bluetooth stethoscope has been developed by Healthy Networks, a company based in Talinn, Estonia. The device can analyze sounds from the lungs and help to diagnose or monitor a variety of respiratory conditions, with an initial focus on pneumonia and COPD.
The aim was to create a low-cost (the device costs as little as $45) technology that people could keep at home and use if they suspect to be were a respiratory illness or to monitor a pre-existing condition. With many respiratory illnesses, such as pneumonia, timely diagnosis and intervention is critical to avoid serious illness or death.
Ha...
Source: Medgadget - December 9, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Cardiology Diagnostics Exclusive Geriatrics Pediatrics Source Type: blogs
MissionGO and MediGO Complete Successful Organ Deliveries in Unmanned Flights
MissionGO, a provider of unmanned aviation solutions, and Nevada Donor Network, an organ procurement organization (OPO) serving the state of Nevada, have recently completed two successful test flights in Las Vegas carrying a human organ and human tissue via an Unmanned Aircraft System (UAS). MediGO provided the technological services needed for collection and communication of critical data about OPO resources and organs across the transplant ecosystem.
The first flight transported research corneas in an urban environment—from Southern Hills Hospital and Medical Center to Dignity Health-St. Rose Dominican, San Martín ...
Source: Medgadget - December 4, 2020 Category: Medical Devices Authors: Alice Ferng Tags: Cardiac Surgery Emergency Medicine Exclusive Pediatrics Thoracic Surgery Source Type: blogs
Delayed GI Symptoms and a Liver Transplant
A 16-year-old boy presented to an emergency department in rural Pennsylvania for nausea, vomiting, and diarrhea. He reported diffuse abdominal cramping that had started two hours earlier. Shortly prior to arrival, he had multiple episodes of nonbloody diarrhea and emesis. He had no significant past medical history, and was not currently taking any medications or supplements. Initially, the history he gave was limited due to a language barrier. His sister was also being evaluated for similar symptoms.The boy's vital signs were a heart rate of 130 bpm, a blood pressure of 100/50 mm Hg, a respiratory rate of 26 bpm, an oxy...
Source: The Tox Cave - November 30, 2020 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Fight Aging! Newsletter, November 16th 2020
This study conclusively demonstrates the long-speculated relationship between aging, gene regulation, and somatic damage. The results open up new avenues of research with practical implications. If the same level of coordination reduction between genes is indeed a leading cause for aging phenomena, there may be a need to change course in current efforts to develop aging treatments.
Using Oligodendrocyte Extracellular Vesicles to Induce Tolerance to Myelin as a Treatment for Multiple Sclerosis
https://www.fightaging.org/archives/2020/11/using-oligodendrocyte-extracellular-vesicles-to-induce-tolerance-to-myelin-...
Source: Fight Aging! - November 15, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Does lupus or arthritis affect your prognosis if you get COVID-19?
Soon after the coronavirus pandemic began, we learned that older adults and people with certain chronic conditions, such as high blood pressure or diabetes, are at increased risk for severe COVID-19. One condition on that list is an immunocompromised state (a weakened immune system). This can be due to a number of conditions, including having had an organ transplant, having HIV, or taking medications that suppress the immune system.
If you have an autoimmune condition such as rheumatoid arthritis or lupus (also called systemic lupus erythematosus), you may wonder how this affects your risk. It’s thought that these condit...
Source: Harvard Health Blog - November 9, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Autoimmune diseases Bones and joints Coronavirus and COVID-19 Source Type: blogs
Fight Aging! Newsletter, November 9th 2020
In this study, young adult mice were submitted to endurance exercise training and the function, differentiation, and metabolic characteristics of satellite cells were investigated in vivo and in vitro.
We found that injured muscles from endurance-exercised mice display improved regenerative capacity, demonstrated through higher densities of newly formed myofibres compared with controls (evidenced by an increase in embryonic myosin heavy chain expression), as well as lower inflammation (evidenced by quantifying CD68-marked macrophages), and reduced fibrosis. Enhanced myogenic function was accompanied by an increased ...
Source: Fight Aging! - November 8, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, October 26th 2020
In conclusion, all NAFLD histological stages were associated with significantly increased overall mortality, and this risk increased progressively with worsening NAFLD histology. Most of this excess mortality was from extrahepatic cancer and cirrhosis, while in contrast, the contributions of cardiovascular disease and HCC were modest.
BMP6 as a Target for Pro-Angiogenic Therapies
https://www.fightaging.org/archives/2020/10/bmp6-as-a-target-for-pro-angiogenic-therapies/
Today's research materials are focused on the fine details of angiogenesis, the formation of new blood vessels, and point to BMP6 as a p...
Source: Fight Aging! - October 25, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, October 19th 2020
In conclusion, we found that regardless of the presence of multimorbidity, engaging in a healthier lifestyle was associated with up to 6.3 years longer life for men and 7.6 years for women; however, not all lifestyle risk factors equally correlated with life expectancy, with smoking being significantly worse than others.
A Hydrogel Scaffold to Encourage Peripheral Nerve Regeneration
https://www.fightaging.org/archives/2020/10/a-hydrogel-scaffold-to-encourage-peripheral-nerve-regeneration/
The nervous system of mammals is poorly regenerative at best. The use of implantable scaffold materials is one of th...
Source: Fight Aging! - October 18, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Big Pharma Senolytics Programs are Getting Underway
Biotech startups working in a new and credible field of clinical development only have a few years before large pharmaceutical companies take notice and begin to enter the arena. This shift in the competitive landscape is a good thing for patients, as a great deal more funding will be deployed to expand the space of possible therapies. Further, small companies with viable approaches are more likely to be acquired, increasing the odds that specific programs will continue through to clinical trials. It doesn't solve the problem of the burdensome regulatory system that slows all progress, but it does improve the odds of pushi...
Source: Fight Aging! - October 15, 2020 Category: Research Authors: Reason Tags: Longevity Industry Source Type: blogs
To What Degree do Bodily Microbiomes Beyond the Gut Contribute to the Chronic Inflammation of Aging?
Most research on the microbial life of the body in the context of aging is focused on the gut microbiome, though a fair amount of investigation of oral microbial populations also takes place. In both cases, changes occur with age that allow harmful species of microbe to prosper, contributing to the chronic inflammation of aging. In the case of the gut microbiome, fecal microbiota transplantation from young individuals to old individuals has been shown in animal studies to reverse detrimental changes and improve health and life span. This has yet to be earnestly attempted for other microbial populations of the body that pla...
Source: Fight Aging! - October 12, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, October 12th 2020
We report that FMT from aged donors led to impaired spatial learning and memory in young adult recipients, whereas anxiety, explorative behaviour, and locomotor activity remained unaffected.
This was paralleled by altered expression of proteins involved in synaptic plasticity and neurotransmission in the hippocampus. Also, a strong reduction of bacteria associated with short-chain fatty acids (SCFAs) production (Lachnospiraceae, Faecalibaculum, and Ruminococcaceae) and disorders of the CNS (Prevotellaceae and Ruminococcaceae) was observed. Finally, the detrimental effect of FMT from aged donors on the CNS was confir...
Source: Fight Aging! - October 11, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, October 5th 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - October 4, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Using Artificial Classes To Settle Mass Litigation: What Ginsburg Knew
Walter OlsonLast week theSixth Circuit rejected a federal judge ’s novel certification of an unusual “negotiating class” aimed at promoting a global settlement between opiate manufacturers and cities and counties around the country that have sued them. The designated class would have included thousands of cities and counties around the country that have not filed suit, and the way in which it would have handled their legal interests was assailed from many directions as lacking in fairness. Last week ’s ruling triumphantly vindicates the prescience of the late Justice Ruth Bader Ginsburg, the modern C...
Source: Cato-at-liberty - September 28, 2020 Category: American Health Authors: Walter Olson Source Type: blogs
Fight Aging! Newsletter, September 28th 2020
In conclusion, it remains unclear if brain-specific regional and temporal changes occur in the expression of the different APP variants during AD progression. Since APP is also found in blood cells, assessing the changes in APP mRNA expression in peripheral blood cells from AD patients has been considering an alternative. However, again the quantification of APP mRNA in peripheral blood cells has generated controversial results.
Brain APP protein has been analyzed in only a few studies, probably as it is difficult to interpret the complex pattern of APP variants and fragments. We previously characterized the soluabl...
Source: Fight Aging! - September 27, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
EchoNous KOSMOS 3-in-1 Ultrasound, Electronic Stethoscope, and ECG Helps with COVID-19
EchoNous, a developer of novel ultrasounds, has found a way to leverage multiple critical clinical technologies within a single device. The result is KOSMOS, a handheld 3-in-1 device consisting of an ultrasound, electronic stethoscope, and an ECG, all linked via artificial technology.
When COVID-19 was hitting NYC earlier this year, EchoNous was able to use KOSMOS to help diagnose COVID patients and to inform on treatment strategies. We had a lovely chat with Dr. Richard Hoppmann, a key member of EchoNous, Clinical Professor of Internal Medicine at the University of South Carolina, and the Director of the Ultrasound I...
Source: Medgadget - September 21, 2020 Category: Medical Devices Authors: Alice Ferng Tags: Cardiology Critical Care Diagnostics Exclusive Informatics Medicine Public Health Source Type: blogs
