How Did We Screw A Pandemic Up So Bad?
We’re still in the thick of things when it comes to the coronavirus pandemic. Countries are bracing themselves for a second wave. Scientists are still racing to find a vaccine. We wrote a whole e-book with resources to help you in the fight against COVID-19 while indoors. And we even had to tackle the conspiracy theories that captured way too many people’s imagination.
Thankfully, those conspiracy theories represented the thoughts and actions of an irrational minority. But even the slow and misguided actions of the rational majority further escalated and worsened the crisis. In our tech-aided, always-connected and i...
Source: The Medical Futurist - September 9, 2020 Category: Information Technology Authors: Prans Tags: Artificial Intelligence Future of Pharma Healthcare Policy Video china leadership Fauci Trump pandemic second wave covid-19 Bolsonaro U.S. vaccine new normal Source Type: blogs
Fight Aging! Newsletter, September 7th 2020
In conclusion, using a large cohort with rich health and DNA methylation data, we provide the first comparison of six major epigenetic measures of biological ageing with respect to their associations with leading causes of mortality and disease burden. DNAm GrimAge outperformed the other measures in its associations with disease data and associated clinical traits. This may suggest that predicting mortality, rather than age or homeostatic characteristics, may be more informative for common disease prediction. Thus, proteomic-based methods (as utilised by DNAm GrimAge) using large, physiologically diverse protein sets for p...
Source: Fight Aging! - September 6, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, August 31st 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - August 30, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Targeted Therapeutics for Critical Illnesses: Interview with Jason Springs, CEO of Endpoint Health
With the COVID-19 pandemic, critical illnesses, such as Acute Respiratory Distress Syndrome and sepsis are coming into the spotlight. Despite their severity and risk for patients, critical illnesses remain understudied and lack the number of treatment options of many other diseases with a similar level of mortality and morbidity.
Part of the challenge lies in the time sensitivity of such conditions, whereby clinicians have little time to make treatment decisions and typically can’t tailor the treatment for individual patient needs. The quest to develop more tailored treatments for such illnesses is what drives Endpoin...
Source: Medgadget - August 13, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Critical Care Exclusive Informatics Medicine Source Type: blogs
AI System Decides When to Help Diagnose X-Rays
Artificial intelligence is playing an ever larger role in modern clinical care. For example, there are already imaging processing systems that are able to automatically spot polyps during colonoscopies and help analyze head CT scans for hemorrhage and mass effect. A universal issue with such systems is that they do not take into account how experienced, busy, or in need of actual help a given clinician is. A team of MIT researchers has now developed a machine learning system that can adjust how it makes clinically relevant decisions, whether to let an expert decide something or to do so itself, and to do so while taking in...
Source: Medgadget - August 11, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Informatics Radiology Source Type: blogs
Fight Aging! Newsletter, July 13th 2020
In conclusion, sitting for prolonged periods of time without interruption is unfavorably associated with DBP and HDL cholesterol.
Exercise Slows Inappropriate Growth of Blood Vessels in a Mouse Model of Macular Degeneration
https://www.fightaging.org/archives/2020/07/exercise-slows-inappropriate-growth-of-blood-vessels-in-a-mouse-model-of-macular-degeneration/
Excessive growth of blood vessels beneath the retina is a proximate cause of blindness in conditions such as macular degeneration. Researchers here provide evidence for physical activity to be influential in the pace at which this process of tissu...
Source: Fight Aging! - July 12, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Digital Health Ventures That Flew Too Close To The Sun
1.5 billion: that’s the number, in dollars, Forbes put for Proteus’ valuation last year. Dubbed as a healthcare unicorn, the startup even raised over $500 million in venture capital. It made headlines for developing the first-ever FDA-approved digital pill, one equipped with an ingestible and trackable sensor to monitor treatment compliance.
Researchers even proved the technology’s worth. In 2019, an independent study investigated the Proteus’ digital pill. They found it to be accurate, and even improved adherence of tuberculosis patients using oral pills equipped with Proteus’ system.
https://ww...
Source: The Medical Futurist - July 7, 2020 Category: Information Technology Authors: Prans Tags: Artificial Intelligence Future of Medicine Future of Pharma Genomics AI cancer IBM google deepmind theranos Watson fail digital pill proteus deus ex machina tech giants finances otsuka Nightingale Source Type: blogs
Robotic Transcranial Doppler for Stroke Detection and Risk Assessment in COVID: Interview with Diane Bryant, Neural Analytics
Emerging evidence suggests that COVID-19 patients are at a higher risk of stroke and promptly diagnosing and treating such patients is a priority in hospitals across the world. Moreover, identifying which COVID-19 patients are at increased risk of developing a stroke is also important, and may help with preemptive treatment and monitoring.
The Lucid Robotic System, developed by LA-based Neural Analytics, is a transcranial doppler system that allows clinicians to identify clots and changes in blood flow in the brain in real time, without needing a specialized technician. The device is robotically assisted and automat...
Source: Medgadget - July 6, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Critical Care Emergency Medicine Exclusive Neurology Neurosurgery Source Type: blogs
Fight Aging! Newsletter, July 6th 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - July 5, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A Virtual Care Platform for Respiratory Illness: Interview with Stacie Ruth, CEO of AireHealth
AireHealth, a medtech company based in Orlando, Florida, currently offers a portable nebulizer and companion app for respiratory patients aged two and over. The small nebulizer can be charged using a micro USB charger and then placed in a bag or pocket for easy transport and use on the move. The companion app is geared toward increasing patient engagement and medication adherence, which is important in maximizing therapeutic outcomes among chronic respiratory patients.
Recently, AireHealth announced a merger with BreathResearch, a respiratory healthcare company based in Silicon Valley that specializes in detection and m...
Source: Medgadget - July 2, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Informatics Medicine Telemedicine AireHealth Source Type: blogs
Fight Aging! Newsletter, June 29th 2020
In conclusion, metabolomics is a promising approach for the assessment of biological age and appears complementary to established epigenetic clocks.
Sedentary Behavior Raises the Risk of Cancer Mortality
https://www.fightaging.org/archives/2020/06/sedentary-behavior-raises-the-risk-of-cancer-mortality/
Living a sedentary lifestyle is known to be harmful to long term health, raising the risk of age-related disease and mortality. Researchers here show that a sedentary life specifically increases cancer mortality, and does so independently of other factors. This is one of many, many reasons to maintain a r...
Source: Fight Aging! - June 28, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Autoimmune lung disease: Early recognition and treatment helps
A man who was diagnosed with rheumatoid arthritis (RA) five years ago sees his rheumatologist for a follow-up visit. Fortunately, his arthritis is well controlled through medication. He can walk and do all his daily activities without pain. But over the past six months, he’s been feeling short of breath when climbing stairs. He has an annoying dry cough, too. COVID-19? That’s ruled out quickly. But a CT scan of his chest reveals early fibrosis (scarring) of the lungs, most likely related to rheumatoid arthritis. “I can finally walk normally, and now I can’t breathe when I walk!” says the frustrated patient, whose...
Source: Harvard Health Blog - June 24, 2020 Category: Consumer Health News Authors: Paul F. Dellaripa, MD Tags: Arthritis Autoimmune diseases Health Inflammation Lung disease Source Type: blogs
Fight Aging! Newsletter, June 15th 2020
In this study, we used markers to monitor the formation of SGs in Caenorhabditis elegans. We found that, in addition to acute heat stress, SG formation could also be triggered by dietary changes, such as starvation and dietary restriction (DR). We found that HSF-1 is required for the SG formation in response to acute heat shock and starvation but not DR, whereas the AMPK-eEF2K signaling is required for starvation and DR-induced SG formation but not heat shock. Moreover, our data suggest that this AMPK-eEF2K pathway-mediated SG formation is required for lifespan extension by DR, but dispensable for the longevity by reduced ...
Source: Fight Aging! - June 14, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Network Medicine in the Fight Against COVID-19
COVID-19 forced stakeholders in the healthcare landscape to adopt a new perspective in this sphere. Telemedicine rose to fame as a ready-made solution; artificial intelligence’s contribution became more apparent from early outbreak predictions to resource management; and digital health technologies lent a helping hand early on.
Another promising area joining the fight is network medicine, a branch of network science. The latter field studies the interaction between actors within a network. Such analyses are applicable to virtually any sector, from the world wide web through social networks to how molecules interact wi...
Source: The Medical Futurist - May 21, 2020 Category: Information Technology Authors: Prans Tags: Network medicine Artificial Intelligence Biotechnology Telemedicine & Smartphones AI MIT coronavirus covid covid19 vaccine research pandemic network science Albert-László Barabási Source Type: blogs
Fight Aging! Newsletter, May 18th 2020
This study provides direct evidence for the contribution of gut microbiota to the cognitive decline during normal aging and suggests that restoring microbiota homeostasis in the elderly may improve cognitive function.
On Nutraceutical Senolytics
https://www.fightaging.org/archives/2020/05/on-nutraceutical-senolytics/
Nutraceuticals are compounds derived from foods, usually plants. In principle one can find useful therapies in the natural world, taking the approach of identifying interesting molecules and refining them to a greater potency than naturally occurs in order to produce a usefully large therap...
Source: Fight Aging! - May 17, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
