How can exercise prevent cardiovascular disease? Cardiology Basics
Dr. Paul Dudley White, the famous physician who has taught many a luminary in the field of cardiology once wrote that heart disease before eighty is our fault and not God’s will or nature’s will.
This means that he recognized long back, the role of life-style modification in preventing heart disease. Exercise in a regular pattern is one of the important life style modifications which everyone can adopt to prevent or delay cardiovascular disease. Exercise helps in various ways for prevention of cardiovascular disease. In those with established cardiovascular disease, graded exercise programs can promote the formation o...
Source: Cardiophile MD - October 15, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
Maccheroni alla bolognese
Before there was Stanley Tucci’s Searching for Italy, there was Regional Italian Cuisine, a cookbook tour of Italy’s regions through its foods and recipes. While Stanley’s show is a light aperitivo, this book is the ten course meal, with recipes for dishes that will make you feel like you’re one of the Famiglia.
Each chapter of Regional Italian Cuisine focuses on a different region of Italy, summarizing in sequential, gorgeous two-page spreads of perfectly balanced text and photos its climate, crops, food specialties, regional events and sights to see. It then follows with short, well-written ...
Source: The Blog That Ate Manhattan - October 13, 2022 Category: Primary Care Authors: Margaret Polaneczky, MD Tags: Pasta Rice & Potatoes Bolognese Bolognese sauce Emilia-Romagna italian Italy Italy regional cuisine Meat sauce Ragu recipe Regional Italian Cuisine Source Type: blogs
What is dobutamine stress echocardiography? Cardiology Basics
Usual stress test for the heart is exercise ECG in which serial ECG recordings are done during a graded exercise protocol, usually on a treadmill. There are certain conditions like left bundle branch block in which an exercise ECG becomes uninterpretable. Some persons are unable to exercise on a treadmill due to illness or disability. In such situations dobutamine infusion is given instead of exercise, to increase heart rate and myocardial contractility, thereby increasing the workload of myocardium. Echocardiograms are taken then to assess the response of the myocardium to stress. This is known as dobutamine stress echoc...
Source: Cardiophile MD - October 11, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
Important blood tests in relation to the heart – Cardiology Basics
Important blood tests in relation to the heart – Cardiology Basics
Here are some important blood tests in relation to the heart. Normal ranges of some of these tests may vary between labs.
Cholesterol is a type of fat found in the blood and has a role in the development of atherosclerosis in the coronary arteries as well as other arteries. Desirable value of total cholesterol in blood is less than 200 milligrams per decilitre.
Triglycerides is another type of fat found in the blood. Desirable value is less than 150 milligrams per decilitre. Very high levels of triglycerides carry a risk of pancreatitis. Calorie restr...
Source: Cardiophile MD - October 11, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
Here Is How Digital Health Devices Helped Me Recover From A Serious Infection
This article – like all our articles and technology reviews – was not sponsored by the company. However, having all these devices available allowed me to track a good amount of data on a single platform – which was comfortable, but by no means necessary, you could do the same with devices from a number of manufacturers)
Here is what I learned as the disease progressed
The sleep sensor showed my average heart rate (HR) was above 80 even during my sleep during the acute phase of the infection, while it is around 55 during my resting hours normally. I was able to track when the acute phase ended ...
Source: The Medical Futurist - October 6, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF E-Patients Health Sensors & Trackers digital health digital health sensors recovery Source Type: blogs
Conductive Cotton Thread for Wearable Sensors in Commercial Textiles
Imperial College London researchers created a conductive cotton thread that can undergo a computerized embroidery process for incorporation into commercially produced textiles, such as t-shirts and face masks. The thread, called PECOTEX, can be used to create wearable health sensors, such as heart rate monitors, breathing monitors and even gas sensors, including ammonia sensors for the breath, which can provide information on liver and kidney function.
The embroidered sensors are machine washable and are stronger and more conductive than previously developed conductive threads. The major benefit, though, is the thr...
Source: Medgadget - October 5, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Cardiology Materials Medicine Telemedicine imperialcollege Source Type: blogs
Fight Aging! Newsletter, October 3rd 2022
In conclusion, based on the analysis of proteomics and transcriptome, we identified four SRMs that may affect aging and speculated their possible mechanisms, which provides a new target for preventing aging, especially skin aging.
A Popular Science Article on the State of Epigenetic Clocks
https://www.fightaging.org/archives/2022/09/a-popular-science-article-on-the-state-of-epigenetic-clocks/
This popular science article is a good view of the present state of development and use of epigenetic clocks, covering the issues as well as the promise. Epigenetic age can be measured, with many different clocks...
Source: Fight Aging! - October 2, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Rapamycin in Early Life Delays Development and Modestly Extends Life Span in Mice
As a general rule, 10% life extension in mice via metabolic alteration is uninteresting. It depends on the fine details, of course, but most age-slowing interventions so far discovered are in some way upregulating cellular stress response mechanisms, or adjusting growth hormone signaling. Neither of these approaches works anywhere near as well in long-lived mammals, such as our own species, as it does in short-lived mammals, such as mice, and in lower animal species. Short-lived species have life spans that are very plastic in response to environmental cues, such as the lack of nutrients that provoke greater stress respons...
Source: Fight Aging! - September 30, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, September 26th 2022
This study examined the dose-response association between daily step count and intensity and incidence of all-cause dementia among adults in the UK. This was a UK Biobank prospective population-based cohort study (February 2013 to December 2015) with 6.9 years of follow-up (data analysis conducted May 2022). A total of 78,430 of 103,684 eligible adults aged 40 to 79 years with valid wrist accelerometer data were included. Registry-based dementia was ascertained through October 2021.
We found no minimal threshold for the beneficial association of step counts with incident dementia. Our findings suggest that approxima...
Source: Fight Aging! - September 25, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Immunotherapy Destroys Activated Fibroblasts to Reduce Fibrosis
Researchers here report on an approach to treating fibrosis via vaccination to target distinctive molecular features of activated fibroblasts, the cells that generate the scar-like deposits of excess collagen that are characteristic of fibrosis. This scarring disrupts tissue structure and function. At the present time, there are no truly effective treatments for fibrosis in the clinic, and it is a problem characteristic of old age that affects numerous vital organs, such as heart, lungs, liver, and kidneys. Approaches that can efficiently reverse the progression of fibrosis are very much needed.
Fibrosis is the fi...
Source: Fight Aging! - September 22, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, September 19th 2022
Conclusion
Use of the Khavinson peptides and melatonin in combination in this way, at this dose, negatively impacts the thymus, producing a reduction in active tissue and increase in atrophy to fatty tissue. The degree to which this atrophy occurred is greater than one would expect to take place over nine months of aging at this stage of life.
Why did this outcome occur, given the animal studies showing thymic regrowth, and the studies showing reduced later life mortality following use of thymogen? We can only speculate. Firstly, the dose makes the poison, and the dosing here may have been too high, too frequ...
Source: Fight Aging! - September 18, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
On Reverse Cholesterol Transport Solutions to Atherosclerosis
Atherosclerosis, the condition that kills upwards of a quarter of humanity at the present time, is a failure of cholesterol transport. Cholesterol is made in the liver and transported out into the body in the bloodstream, attached to LDL particles. All cells need cholesterol. Some of this LDL-cholesterol ends up stuck in blood vessel walls in too large an amount, or oxidized into toxic forms, aggravating the blood vessel tissues. Macrophage cells ingest this excess cholesterol and then attach it to HDL particles that return the cholesterol to the liver for excretion. The latter part of this complicated system is called rev...
Source: Fight Aging! - September 13, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
What I loved about radiology was the magic
An excerpt from Balance, Pedal, Breathe: A Journey Through Medical School. What I loved about radiology was the magic. Invisible beams revealed mysteries no one could see on the surface of a person. Each of us harbors a secret life. This might be a simple quirk of anatomy: a liver lobe that lies a bit
Read more…
What I loved about radiology was the magic originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - September 9, 2022 Category: General Medicine Authors: Claire Unis, MD Tags: Physician Radiology Source Type: blogs
Fight Aging! Newsletter, August 29th 2022
This study demonstrates that adoptive astrocytic Mt transfer enhances neuronal Mn-SOD-mediated anti-oxidative defense and neuroplasticity in the brain, which potentiate functional recovery following ICH.
First Generation Stem Cell Therapies Remain Comparatively Poorly Understood
https://www.fightaging.org/archives/2022/08/first-generation-stem-cell-therapies-remain-comparatively-poorly-understood/
We are something like thirty years into the increasingly widespread use of first generation stem cell therapies. Cells are derived from a variety of sources, processed, and transplanted into patients. Near all...
Source: Fight Aging! - August 28, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Idea that Epigenetic Clocks Will Point to Causes of Aging
This popular science article on the development and present use of epigenetic clocks mentions the view that the clocks will point the way to a better understanding of the causes of aging. I'm dubious that use of the clocks represents a better way forward to that goal than the approach of implementing the various rejuvenation therapies outlined in the SENS proposals. A potential rejuvenation therapy that affects just one potential root cause of aging in isolation will tell us a lot about the importance and validity of that cause; researchers are learning a great deal from the ability to selectively destroy senescent cells, ...
Source: Fight Aging! - August 25, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
