Immunobiology of Xenotransplantation (U19 Clinical Trial Not Allowed)
Funding Opportunity RFA-AI-24-020 from the NIH Guide for Grants and Contracts. The purpose of this notice of funding opportunity (NOFO) is to solicit applications to participate in the Immunobiology of Xenotransplantation Cooperative Research Program (IXCRP), a multi-center program dedicated to resolving immunologic and physiologic barriers to safe and efficacious xenotransplantation using preclinical pig to nonhuman primate (NHP) or human decedent models of pancreatic islet, kidney, heart, lung, or liver xenotransplantation. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 1, 2024 Category: Research Source Type: funding

Immunobiology of Xenotransplantation (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-AI-24-019 from the NIH Guide for Grants and Contracts. The purpose of this notice of funding opportunity (NOFO) is to solicit applications to participate in the Immunobiology of Xenotransplantation Cooperative Research Program (IXCRP), a multi-center program dedicated to resolving immunologic and physiologic barriers to safe and efficacious xenotransplantation using preclinical pig to nonhuman primate (NHP) or human decedent models of pancreatic islet, kidney, heart, lung, or liver xenotransplantation. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 1, 2024 Category: Research Source Type: funding

Limited Competition: Alcohol-associated Hepatitis Clinical Network Integrated Treatment Clinical Trials Data Coordinating Center (U24 - Clinical Trial Required)
Funding Opportunity RFA-AA-24-005 from the NIH Guide for Grants and Contracts. he purpose of this limited competition Notice of Funding Opportunity (NOFO) is to support the Data Coordinating Center of the previously funded program on Late Phase Clinical Trials and Observational Studies in Alcoholic Hepatitis. The existing program of AH Clinical and Translational Network, hereafter termed Alcohol-associated Hepatitis Network, AlcHepNet, has been sponsored by the NIAAA since 2012 and was renewed in 2018. The purpose of this research program is to improve biomedical, psychosocial and quality of life outcomes for patients w...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 7, 2024 Category: Research Source Type: funding

Limited Competition: Alcohol-associated Hepatitis Clinical Network Integrated Treatment Clinical Trials Clinical Centers (U01-Clinical Trial required)
Funding Opportunity RFA-AA-24-004 from the NIH Guide for Grants and Contracts. The purpose of this limited competition Notice of Funding Opportunity (NOFO) is to leverage the established clinical infrastructure of the previously funded program on Late Phase Clinical Trials and Observational Studies in Alcoholic Hepatitis. The existing program of AH Clinical and Translational Network, hereafter termed AlcHepNet, has been sponsored by the NIAAA since 2012 and was renewed in 2018. In the next cycle the program will consist of up to six Clinical Study Sites and one Data Coordinating Center to conduct an integrated treatment...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 6, 2024 Category: Research Source Type: funding

Silvio O. Conte Digestive Diseases Research Core Centers (P30 Clinical Trial Optional)
Funding Opportunity RFA-DK-25-003 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) invites applications for Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs). The DDRCCs are part of an integrated program of digestive and liver diseases research support provided by the NIDDK. The purpose of this Centers program is to bring together basic and clinical investigators as a means to enhance communication, collaboration, and effectiveness of ongoing research related to digestive and/or liver diseases within the NIDDK's mission. DDRCCs are based on the core concept, whereby ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 19, 2023 Category: Research Source Type: funding

Continuation of the Childhood Liver Disease Research Network (ChiLDReN) Scientific and Data Coordinating Center (U24 Clinical Trial Optional)
Funding Opportunity RFA-DK-23-018 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to continue the support the Childhood Liver Disease Research Network (ChiLDReN) to conduct clinical and translational research on rare pediatric liver diseases. ChiLDReN will be composed of a Scientific and Data Coordination Center (DCC), Clinical Centers (CC) , and the NIDDK/NIH as the sponsor of the Network. ChiLDReN will continue clinical and translational research on pediatric liver diseases that include: Biliary Atresia; Alagille syndrome; alpha-1-antitrypsin deficiency; Progr...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 7, 2023 Category: Research Source Type: funding

Continuation of the Childhood Liver Disease Research Network (ChiLDReN) Clinical Centers (U01 Clinical Trial Required)
Funding Opportunity RFA-DK-23-017 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to continue the support the Childhood Liver Disease Research Network (ChiLDReN) to conduct clinical and translational research on rare pediatric liver diseases. ChiLDReN is composed of a Scientific and Data Coordination Center (SDCC) and Clinical Centers (CC). ChiLDReN will continue clinical and translational research on pediatric liver diseases that include: Biliary Atresia; Alagille syndrome; alpha-1-antitrypsin deficiency; Progressive Familial Intrahepatic Cholestasis syndromes;...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 7, 2023 Category: Research Source Type: funding

Limited Competition for the Continuation of the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) Clinical Centers (U01 Clinical Trial Required)
Funding Opportunity RFA-DK-23-515 from the NIH Guide for Grants and Contracts. The purpose of this limited competition notice of funding opportunity (NOFO) is to continue the support of the Clinical Sites of the NASH Clinical Research Network (NASH CRN) as they complete active clinical treatment trials and continue to longitudinally gather biospecimens and data of children and adults with nonalcoholic fatty liver disease (NAFLD), including steatosis, steatohepatitis, and cirrhosis (NAFLD database study). The NASH CRN has been sponsored by the NIDDK since 2002, and renewed in 2009 and 2014. Research in the NASH CRN has b...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 7, 2023 Category: Research Source Type: funding

Human Liver Tissue and Hepatocytes Resource-Related Research Project (R24 Clinical Trial Not Allowed)
Funding Opportunity RFA-DK-23-012 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to support a Human Liver Tissue and Hepatocytes Research Resource (HLTHRR) program to enable the continued availability of human liver tissue and hepatocytes to biomedical researchers. The research resource is expected to facilitate the procurement and preservation of human liver tissue and hepatocytesas well as the distribution of these materials to qualified biomedical researchers. Applications focused on animal liver and/or hepatocytes studies will not be considered responsive to ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 3, 2023 Category: Research Source Type: funding

Liver Cancer Collaborative Projects with the Liver Cirrhosis Network (U01 Clinical Trial Optional)
Funding Opportunity RFA-CA-23-023 from the NIH Guide for Grants and Contracts. Through this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) intends to establish collaborations between liver cancer investigators and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)-funded Liver Cirrhosis Network (LCN) members to advance our understanding of hepatocellular carcinoma (HCC) as the result of liver cirrhosis and its etiologic risks, development, progression, early diagnosis, and treatment. The funds available through this FOA will support new multidisciplinary liver cance...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 30, 2023 Category: Research Source Type: funding

Animal Models for Hepatitis B and C (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-AI-23-022 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages research focused on the development of convenient small animal models that will support infection and replication of HBV and/or HCV, ideally leading to the dichotomous outcomes of clearance and persistence. Alternatively, closely related surrogate virus-host systems or robust xenotransplantation models dually engrafted with human liver cells and human immune systems can be developed. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 28, 2023 Category: Research Source Type: funding

Request for Information (RFI): Priorities for Precision Cancer Prevention of Pancreatic and Liver Cancer Science at NCI
Notice NOT-CA-23-014 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 23, 2022 Category: Research Source Type: funding

Notice of Pre-Application Webinar for RFA-CA-22-031 and RFA-CA-22-032 for Consortium on Translational Research in Early Detection of Liver Cancer
Notice NOT-CA-22-121 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 24, 2022 Category: Research Source Type: funding

Drug Induced Liver Injury Network (DILIN) Clinical Centers (U01 - Clinical Trial Optional)
Funding Opportunity RFA-DK-22-013 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement is to invite applicationsfor for clinical centers for the continuation of the Drug-Induced Liver Injury Network (DILIN). The DILIN Clinical Centers are the components of the Network to identify, enroll and clinically characterize patients eligible for the DILIN. The companion RFA (RFA- DK-22-508) seeks to continue the Data Coordinating Center for DILIN. Drug-induced liver injury (DILI) is one of the more challenging forms of liver disease; both in diagnosis and management. Several hundred d...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 24, 2022 Category: Research Source Type: funding

Limited Competition for the Continuation of the Drug Induced Liver Injury Network Data Coordinating Center (DILIN) (U01 - Clinical Trial Not Allowed)
Funding Opportunity RFA-DK-22-508 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement is a limited competition for the continuation of the Data Coordinating Center of the Drug-induced Liver Injury Network (DILIN). The Data Coordinating Center will provide managerial, logistic, and analytic functions for the DILIN and build a collaboration with the National Center for Natural Products Research (NCNPR), University of Mississippi to attempt the identification of specific hepatotoxic ingredients in Herbal and Dietary Supplements (HDS) implicated in liver toxicity. This RFA and companion [RFA-D...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 24, 2022 Category: Research Source Type: funding