The Med List: ACE Inhibitors
Today I’m starting a new series called The Med List. Once or twice a month, I’d like take a closer look at a single class of home medications and explore the medical implications for our patients who take these meds.
The patient’s medications list holds a wealth of information. Prescribed medications tell us about the patient’s medical history. They also give us clues to the patient’s possible current condition and presentation. Some medicines can better explain the clinical picture in front of us and others can be red flags regarding treatment options and the patients likely response.
Let’s kic...
Source: The EMT Spot - November 9, 2022 Category: Emergency Medicine Authors: Steve Whitehead Tags: EMT Source Type: blogs
Treating Hypertension with Diuretics
This article will explore the types, uses and side effects of treating hypertension with diuretics as a supplement to other ways to lower blood pressure.
Quick Summary
Diuretics are prescribed to encourage kidney function and vascular health and regulate blood pressure.
There are several forms of diuretics with possible side effects and interactions with other drugs and supplements.
Doctors often prescribe them to complement medication or a combination for effective hypertension treatment.
Treating Hypertension and More with Diuretics
Diuretics are the most common medication to manage high b...
Source: The EMT Spot - November 8, 2022 Category: Emergency Medicine Authors: Michael Kutryk Tags: Guides Blood Pressure Source Type: blogs
What is Sepsis Anyway?
Don’t feel bad if you don’t have a really good answer. Most of us don’t. Before I started researching the question two years ago, I didn’t have much of an answer either. People get sick. Some get better. Some get worse. If they get really sick they transition into septic shock. End of story.
As an EMS educator, I didn’t go into too much more detail than that, so my own lack of knowledge was carried forward by my EMT students and the cycle continued. Sure, I could turn around and blame my instructor, but here’s a better idea, let’s end the cycle right now.
Here is your one stop shopping guide to the path...
Source: The EMT Spot - November 7, 2022 Category: Emergency Medicine Authors: Steve Whitehead Tags: EMT Source Type: blogs
Basic Functions of Abdominal Organs
Most EMT level providers are square on the primary function of the stomach. We can name several things our liver is doing for us and we get the whole kidney concept as well. But when we start drifting beyond the basics, the conversation can turn fuzzy.
OK … It’s been a little while since I studied this. What was the spleen doing again? Something about the immune system right? Oh, the Pancreas that produces Insulin doesn’t it? Or was that the gallbladder?
Fear not. I put together a handy reference for you. Here’s a list of all those abdominal organs for your review. Now you can sort your large...
Source: The EMT Spot - November 7, 2022 Category: Emergency Medicine Authors: Steve Whitehead Tags: EMT Source Type: blogs
In which situations are stress echocardiography useful?
Stress echocardiography is useful when exercise stress test is not feasible due to mobility issues. Stress echocardiography is usually done with dobutamine infusion to stress the myocardium. An important emerging role is in patients being prepared for liver transplantation. They are too sick for a treadmill exercise ECG. Invasive coronary angiography which is another alternative is not ideal due to the coagulation defect in such patients. Stress echocardiography is also useful when exercise ECG is not interpretable due to left bundle branch block. Another important role for stress echocardiography is when hibernating myoc...
Source: Cardiophile MD - November 3, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
Fight Aging! Newsletter, October 31st 2022
This study used mice to evaluate how their lifestyles - eating fatty foods vs. healthy and exercising vs. not - affected the metabolites of their offspring. Metabolites are substances made or used when the body breaks down food, drugs or chemicals, or its own fat or muscle tissue. "We have previously shown that maternal and paternal exercise improve health of offspring. Tissue and serum metabolites play a fundamental role in the health of an organism, but how parental exercise affects offspring tissue and serum metabolites has not yet been investigated."
Researchers used targeted metabolomics - the study of metaboli...
Source: Fight Aging! - October 30, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Enlightened Cream of Tomato Soup
Warning – The story behind this soup is a long one. A melodrama in three acts as it were.
Act I
It all started with a chicken that I purchased some weeks ago, in order to get a single chicken liver to use in a Bolognese ragu. After removing the liver from the little packet stuffed inside the chicken, I put the neck back in the cavity, put the chicken in the freezer and made the Bolognese.
Act II
Two weeks later, I took the chicken out of the freezer, put it in a pot with some veggies and water and cooked it, giving me a meat to make soft tacos for the a couple of dinners and lunches. And also a gorgeous...
Source: The Blog That Ate Manhattan - October 30, 2022 Category: Primary Care Authors: Margaret Polaneczky, MD Tags: Soups cream tomato soup Source Type: blogs
Epigenetic Inheritance of Benefits Resulting from Parental Physical Fitness
This study used mice to evaluate how their lifestyles - eating fatty foods vs. healthy and exercising vs. not - affected the metabolites of their offspring. Metabolites are substances made or used when the body breaks down food, drugs or chemicals, or its own fat or muscle tissue. "We have previously shown that maternal and paternal exercise improve health of offspring. Tissue and serum metabolites play a fundamental role in the health of an organism, but how parental exercise affects offspring tissue and serum metabolites has not yet been investigated."
Researchers used targeted metabolomics - the study of metaboli...
Source: Fight Aging! - October 28, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Implicating Cellular Senescence in the Fibrosis and Inflammation of NASH
Nonalcoholic steatohepatitis, NASH, is a condition characterized by chronic inflammation and fibrosis in the liver. Fibrosis is a malfunction of tissue maintenance, the deposition of excessive, scar-like collagen that disrupts tissue structure and function. Like all fibrotic diseases, means of effectively reversing the progression of NASH are presently lacking. NASH is a lifestyle condition, a consequence of fatty liver and obesity, but losing weight and otherwise changing lifestyle will not significantly reverse established fibrosis and loss of liver function. Where fibrosis and inflammation characterize a condition, we m...
Source: Fight Aging! - October 26, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
The Burden of Somatic Mutation with Age
Mutational damage occurs constantly to nuclear DNA throughout life. Little of that damage goes unrepaired, and little of the lasting breakage occurs in active parts of the genome. Where mutations go unrepaired in active parts of the genome, little of that occurs in important genes. Where it does occur in important genes, that only matters to the extent that (a) the mutation can spread, and (b) the mutation is potentially cancerous. Comparatively few cells in the body have the capacity to create many descendant cells through replication, as the Hayflick limit ensures that near all cells are limited in the number of times th...
Source: Fight Aging! - October 24, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Answer to Case 699
Answer:Clonorchis sinensis/Opisthorchiseggs. The location (South Korea) is consistent withC. sinensis.As noted by Sam, " Both eggs have an abopercular knob and an obvious operculum. So these could be eggs of eitherClonorchis sinensisorOpisthorchisspecies (both liver flukes). We can ' t differentiate based on morphology, but based on the patient being from/living in South Korea, we can likely narrow the identification down toClonorchis sinensis, as Korea is an endemic region for this parasite. WhereasOpisthorichis viverriniis endemic to South East Asia (i.e, Vietnam, Cambodia, Laos, Thailand). Biliary complications can aris...
Source: Creepy Dreadful Wonderful Parasites - October 23, 2022 Category: Parasitology Source Type: blogs
Fight Aging! Newsletter, October 24th 2022
This study shows the uncoupling of lifespan and healthspan parameters (aerobic fitness and spontaneous activity) and provides new insights into SIRT3 function in CR adaptation, fuel utilization, and aging.
HDL Level, Age, and Smoking are the Largest Determinants of Mortality Risk in Old People
https://www.fightaging.org/archives/2022/10/hdl-level-age-and-smoking-are-the-largest-determinants-of-mortality-risk-in-old-people/
An interesting epidemiological study here stratifies the contributions of various metrics to mortality in later life, age 70 and older. The authors find that the largest effects arise...
Source: Fight Aging! - October 23, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
What is the difference between dextrocardia and dextroposition? Cardiology Basics
Dextrocardia means heart is situated in the right hemithorax instead of the left, as a congenital anomaly. In dextroposition, the heart is either pushed to the right or pulled to the right by another abnormality, usually in the lungs. Heart can be pulled to the right when the right lung is collapsed due to some reason, leaving more space on the right side of the chest. Here we have two X-rays illustrating dextrocardia and dextroposition. First one is true dextrocardia while the second is dextroposition due to large pleural effusion on the left side.
In the first one, along with the heart, other viscera have also switched ...
Source: Cardiophile MD - October 20, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
Notes from the Rejuvenation Startup Summit, Held in Berlin in October 2022
We presented recent results showing reversal of liver inflammation and fibrosis in NASH model mice, and noted that we're raising funds to start our clinical development program leading to human trials. Therapies to reverse atherosclerosis progression will follow shortly on the heels of this work on NASH.
Robin Mansukhani of Deciduous Therapeutics discussed their approach to immune system modulation via small molecules, training invariant natural killer cells to attack senescent cells. The point was made that engaging the immune system may be a way to work around many of the present unknowns regarding senescent cell ...
Source: Fight Aging! - October 19, 2022 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
What is TAPVC? Cardiology Basics
TAPVC stands for total anomalous pulmonary venous connection. It is also known as TAPVD or total anomalous pulmonary venous drainage. Normally, pulmonary veins join the left atrium. When it drains to the right atrium through one of the blood vessels leading to the right atrium, it is known as TAPVC. If only some of the four pulmonary veins join the right side of the heart, then it is called PAPVC or partial anomalous pulmonary venous connection.
When all the pulmonary veins join the right side of the heart instead of the left side, an atrial septal defect (ASD) is needed to maintain life. Otherwise body will not get any o...
Source: Cardiophile MD - October 19, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
